scholarly journals More than 10 years after introduction of an acellular pertussis vaccine in infancy: a cross-sectional serosurvey of pertussis in the Netherlands

Author(s):  
Pauline Versteegen ◽  
Guy A.M. Berbers ◽  
Gaby Smits ◽  
Elisabeth A.M. Sanders ◽  
Fiona R.M. van der Klis ◽  
...  
Vaccine ◽  
2004 ◽  
Vol 22 (25-26) ◽  
pp. 3256-3257 ◽  
Author(s):  
Mandy G Keijzer-Veen ◽  
Lianne Holty-van der Wekken ◽  
Rikard E Juttmann ◽  
Ronald de Groot ◽  
Hans C Rümke

Antibiotics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 250
Author(s):  
Louise Witteman ◽  
Herman A. van Wietmarschen ◽  
Esther T. van der Werf

Due to the excessive use of antibiotic and antimycotic treatments, the risk of resistant microbes and fungi is rapidly emerging. Previous studies have demonstrated that many women with (recurrent) urinary tract infection (UTI) and/or vaginal infections (VIs) welcome alternative management approaches to reduce the use of antibiotics and antifungals and avoid short- and long-term adverse effects. This study aims to determine which complementary medicine (CM) and self-care strategies are being used by women suffering from (recurrent) UTI and VI in The Netherlands and how they perceive their effectiveness in order to define directions for future research on safety, cost-effectiveness, and implementation of best practices. A cross-sectional online survey was performed among women, ≥18 years old, with a history of UTIs; 162 respondents were included in the data analysis, with most participants aged between 50 and 64 years (36.4%). The women reported having consulted a CM practitioner for UTI-specific symptoms (23.5%) and VI-specific symptoms (13.6%). Consultations of homeopaths, acupuncturists, and herbal physicians are most often reported. Overall, 81.7% of the women suffering from UTI used complementary or self-care strategies besides regular treatment, and 68.7% reported using CM/self-care strategies to treat vaginal symptoms. UTI- related use of cranberries (51.9%), vitamin C (43.8%), and D-mannose (32.7%) were most reported. Perceived effectiveness was mostly reported for homeopathic remedies and D-mannose. The results showed a substantial burden of UTI and VI on daily and sexual activities. Besides the frequency of use, the indication of perceived effectiveness seems to be an important parameter for further and rigorously designed research to encourage nonantibiotic/antifungal treatment implementation into daily clinical practice.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ursula W. de Ruijter ◽  
Hester F. Lingsma ◽  
Willem A. Bax ◽  
Johan Legemaate

Abstract Background Healthcare rationing can be defined as withholding beneficial care for cost reasons. One form in particular, hidden bedside rationing, is problematic because it may result in conflicting loyalties for physicians, unfair inequality among patients and illegitimate distribution of resources. Our aim is to establish whether bedside rationing occurs in the Netherlands, whether it qualifies as hidden and what physician characteristics are associated with its practice. Methods Cross-sectional online questionnaire on knowledge of -, experience with -, and opinion on rationing among physicians in internal medicine within the Dutch healthcare system. Multivariable ordinal logistic regression was used to explore relations between hidden bedside rationing and physician characteristics. Results The survey was distributed among 1139 physicians across 11 hospitals with a response rate of 18% (n = 203). Most participants (n = 129; 64%) had experience prescribing a cheaper course of treatment while a more effective but more expensive alternative was available, suggesting bedside rationing. Subsequently, 32 (24%) participants never disclosed this decision to their patient, qualifying it as hidden. The majority of participants (n = 153; 75%) rarely discussed treatment cost. Employment at an academic hospital was independently associated with more bedside rationing (OR = 17 95%CI 6.1–48). Furthermore, residents were more likely to disclose rationing to their patients than internists (OR = 3.2, 95%CI 2.1–4.7), while salaried physicians were less likely to do so than physicians in private practice (OR = 0.5, 95%CI 0.4–0.8). Conclusion Hidden bedside rationing occurs in the Netherlands: patient choice is on occasion limited with costs as rationale and this is not always disclosed. To what extent distribution of healthcare should include bedside rationing in the Netherlands, or any other country, remains up for debate.


2021 ◽  
Author(s):  
Mathijs de Haas ◽  
Maarten Kroesen ◽  
Caspar Chorus ◽  
Sascha Hoogendoorn-Lanser ◽  
Serge Hoogendoorn

AbstractIn recent years, the e-bike has become increasingly popular in many European countries. With higher speeds and less effort needed, the e-bike is a promising mode of transport to many, and it is considered a good alternative for certain car trips by policy-makers and planners. A major limitation of many studies that investigate such substitution effects of the e-bike, is their reliance on cross-sectional data which do not allow an assessment of within-person travel mode changes. As a consequence, there is currently no consensus about the e-bike’s potential to replace car trips. Furthermore, there has been little research focusing on heterogeneity among e-bike users. In this respect, it is likely that different groups exist that use the e-bike for different reasons (e.g. leisure vs commute travel), something which will also influence possible substitution patterns. This paper contributes to the literature in two ways: (1) it presents a statistical analysis to assess the extent to which e-bike trips are substituting trips by other travel modes based on longitudinal data; (2) it reveals different user groups among the e-bike population. A Random Intercept Cross-Lagged Panel Model is estimated using five waves of data from the Netherlands Mobility Panel. Furthermore, a Latent Class Analysis is performed using data from the Dutch national travel survey. Results show that, when using longitudinal data, the substitution effects between e-bike and the competing travel modes of car and public transport are not as significant as reported in earlier research. In general, e-bike trips only significantly reduce conventional bicycle trips in the Netherlands, which can be regarded an unwanted effect from a policy-viewpoint. For commuting, the e-bike also substitutes car trips. Furthermore, results show that there are five different user groups with their own distinct behaviour patterns and socio-demographic characteristics. They also show that groups that use the e-bike primarily for commuting or education are growing at a much higher rate than groups that mainly use the e-bike for leisure and shopping purposes.


Author(s):  
Sofia Bastoni ◽  
Christian Wrede ◽  
Achraf Ammar ◽  
Annemarie Braakman-Jansen ◽  
Robbert Sanderman ◽  
...  

(1) Background: The COVID-19 pandemic forced people from all around the globe to strongly modify their daily routines, putting a significant strain on the social aspects of daily lives. While the first wave of the pandemic was a very challenging time in all countries, it is still uncertain whether various lockdown intensities and infection rates differed regarding their psychosocial impact. This work therefore aimed to investigate (i) the psychosocial effects of home confinement in two European countries that underwent different lockdown intensities: Italy and the Netherlands and (ii) the role of communication technology in relation to feelings of loneliness. (2) Methods: A cross-sectional online survey inquiring about different psychosocial variables and the use of and satisfaction towards communication technology was circulated among the general public during the first wave of the COVID-19 pandemic. In total, 629 participants (66% female, 68% from the Netherlands) answered each question twice, referring to “before” and “during” the pandemic. (3) Results: We found significant negative effects of COVID-19 home confinement on depressive feelings (p < 0.001, %∆ = +54%), loneliness (p < 0.001, %∆ = +37.3%), life satisfaction (p < 0.001, %∆ = −19.8%) and mental wellbeing (p < 0.001, %∆ = −10.6%) which were accompanied with a significantly increased need for psychosocial support (p < 0.001, %∆ = +17.3%). However, the magnitude of psychosocial impact did not significantly differ between residents undergoing a more intense (Italy) versus a less intense (Netherlands) lockdown, although the decrease in social participation was found to be significantly different for both countries (z = −7.714, p < 0.001). Furthermore, our findings demonstrate that the increase in loneliness was associated with the adoption of new digital communication tools (r = 0.21, p < 0.001), and significantly higher for individuals who started to adopt at least one new digital communication tool during confinement than for those who did not (z = −4.252, p < 0.001). (4) Conclusions: This study highlights that, although COVID-19 home confinement significantly impacted psychosocial wellbeing during the first wave of the pandemic, this impact did not differ based on lockdown intensity. Recognizing the increasing adoption of digital communication technology in an attempt to reduce lockdown loneliness, future studies should investigate what is needed from the technology to achieve this effect.


Vaccine ◽  
1999 ◽  
Vol 18 (9-10) ◽  
pp. 931-940 ◽  
Author(s):  
Susan van den Hof ◽  
Guy A.M. Berbers ◽  
Hester E. de Melker ◽  
Marina A.E. Conyn-van Spaendonck

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