Preparation of Hollow Mesoporous Prussian Blue Coated with Mesoporous Silica Shell Nanocubes for Photothermal Therapy and Drug Carrier

2022 ◽  
pp. 131697
Author(s):  
Xiao Mei ◽  
Yue Han ◽  
Jingjing Xi ◽  
Juan Liu ◽  
Lingyun Xu ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Prussian Blue ◽  
Photothermal Therapy ◽  
Drug Carrier ◽  
Silica Shell

scholarly journals Gold–silica quantum rattles for multimodal imaging and therapy

2015 ◽  
Vol 112 (7) ◽  
pp. 1959-1964 ◽  
Author(s):  
Mathew Hembury ◽  
Ciro Chiappini ◽  
Sergio Bertazzo ◽  
Tammy L. Kalber ◽  
Glenna L. Drisko ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Gold Nanoparticles ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Drug Carrier ◽  
Material Design ◽  
Tumor Burden ◽  
Silica Shell ◽  
Innovative Material

Gold quantum dots exhibit distinctive optical and magnetic behaviors compared with larger gold nanoparticles. However, their unfavorable interaction with living systems and lack of stability in aqueous solvents has so far prevented their adoption in biology and medicine. Here, a simple synthetic pathway integrates gold quantum dots within a mesoporous silica shell, alongside larger gold nanoparticles within the shell’s central cavity. This “quantum rattle” structure is stable in aqueous solutions, does not elicit cell toxicity, preserves the attractive near-infrared photonics and paramagnetism of gold quantum dots, and enhances the drug-carrier performance of the silica shell. In vivo, the quantum rattles reduced tumor burden in a single course of photothermal therapy while coupling three complementary imaging modalities: near-infrared fluorescence, photoacoustic, and magnetic resonance imaging. The incorporation of gold within the quantum rattles significantly enhanced the drug-carrier performance of the silica shell. This innovative material design based on the mutually beneficial interaction of gold and silica introduces the use of gold quantum dots for imaging and therapeutic applications.

pH-Sensitive Gold Nanorods with a Mesoporous Silica Shell for Drug Release and Photothermal Therapy

2015 ◽  
Vol 2015 (13) ◽  
pp. 2277-2284 ◽  
Author(s):  
Ting Zhang ◽  
Zeyang Ding ◽  
Huiming Lin ◽  
Liru Cui ◽  
Chunyu Yang ◽  
...  
Keyword(s):  
Drug Release ◽  
Mesoporous Silica ◽  
Gold Nanorods ◽  
Photothermal Therapy ◽  
Silica Shell ◽  
Ph Sensitive

Scalable Synthesis of Multicomponent Multifunctional Inorganic Core@Mesoporous Silica Shell Nanocomposites

2021 ◽  
pp. 112272
Author(s):  
Muling Zeng ◽  
Ying Shu ◽  
Marina Parra-Robert ◽  
Diti Desai ◽  
Hongzhi Zhou ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Shell ◽  
Scalable Synthesis

AIE luminogen-functionalised mesoporous silica nanoparticles as nanotheranostic agents for imaging guided synergetic chemo-/photothermal therapy

2017 ◽  
Vol 4 (5) ◽  
pp. 833-839 ◽  
Author(s):  
Zhiying Fan ◽  
Li Ren ◽  
Wenjing Zhang ◽  
Dongdong Li ◽  
Guoqing Zhao ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Photothermal Therapy ◽  
Cell Imaging ◽  
Mesoporous Silica Nanoparticles

A novel AIE luminogen-functionalised nanotheranostic platform for cell imaging and simultaneous chemo- and photothermal therapies.

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