The role of Mediterranean type of diet on the development of cancer and cardiovascular disease, in the elderly: A systematic review

Maturitas ◽  
2010 ◽  
Vol 65 (2) ◽  
pp. 122-130 ◽  
Author(s):  
Stefanos Tyrovolas ◽  
Demosthenes B. Panagiotakos
2020 ◽  
pp. 219256822094803
Author(s):  
Barry Ting Sheen Kweh ◽  
Hui Qing Lee ◽  
Terence Tan ◽  
Joost Rutges ◽  
Travis Marion ◽  
...  

Study Design: Systematic review. Objective: Spinal orthoses have been generally used in the management of osteoporotic vertebral fractures in the elderly population with purported positive biomechanical and functional effects. To our knowledge, this is the first systematic review of the literature examining the role of spinal orthoses in osteoporotic elderly patients who sustain low energy trauma vertebral fractures. Methods: A systematic literature review adherent to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines was conducted. Methodical searches utilizing MEDLINE, EMBASE, Google Scholar, and Cochrane Databases was performed. Results: Of the 2019 articles initially retrieved, 7 published articles (4 randomized controlled trials and 3 prospective cohort studies) satisfied the inclusion criteria. Five studies reported improvement in quantitative measurements of spinal column stability when either a rigid or semirigid orthosis was used, while 1 study was equivocal. The studies also showed the translation of biomechanical benefit into significant functional improvement as manifested by improved postural stability and reduced body sway. Subjective improvement in pain scores and quality of life was also noted with bracing. Conclusion: The use of spinal orthoses in neurologically intact elderly patients aged 60 years and older with osteoporotic compression vertebral fractures results in improved biomechanical vertebral stability, reduced kyphotic deformity, enhanced postural stability, greater muscular strength and superior functional outcomes.


2017 ◽  
Vol 2 (1) ◽  
pp. 76-89
Author(s):  
A.A Norasteh ◽  
H Zarei ◽  
P Pour Mahmoodian ◽  
◽  
◽  
...  

2021 ◽  
Author(s):  
Aiman Hilmi Asaduddin ◽  
Shafira Yasmine Anshari ◽  
Agni Shalha Ali ◽  
Ardhia Fefrine Indarta ◽  
Muhammad Adrianes Bachnas ◽  
...  

Abstract Background There are two central dogmas between the pathophysiology of preeclampsia, the placental origin and the extra-placental origin. Recent findings found that women with a history of preeclampsia are at higher risk of cardiovascular disease and death because of cardiovascular disease. This finding leads to the extra-placental origin. During normal pregnancy, the maternal cardiovascular system undergoes modification. However, hemodynamic and vascular modification are disrupted in women who develop preeclampsia. NT-proBNP is a biomarker that indicates the disruption of the cardiovascular system and can predict the complication of preeclampsia. Based on that information, we would like to investigate the roles of NT-proBNP plasma levels in predicting maternal and fetal complications of preeclampsia women. Besides, we also investigate the roles of NT-proBNP plasma levels in predicting the severity and onset of preeclampsia women and the sensitivity and specificity of NT-proBNP plasma levels in preeclamptic women.MethodsWe designed and registered a study protocol for a systematic review. This study aims to investigate the roles of NT-proBNP plasma levels in predicting maternal and fetal complications of preeclampsia women. The Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy was used to structure our methodological approach and the Preferred Reporting Items for a Systematic Review and Meta-Analysis Protocols guidelines in reporting the findings of this review. We will search literature in Hinari, Cochrane Library, ScienceDirect, and Scopus database. Then, we will search the grey literature in OCLC’s OAISTER. Randomized controlled trials and observational studies will be included in the analysis. Three reviewers will independently screen articles, extract data, and evaluate for quality and bias using Newcastle-Ottawa Scale. Studies were included according to the following procedures: (1) Identification, Duplication of articles and non-original research articles will be excluded; (2) Title and Abstract Screening, RCT and observational studies and focused on NT-proBNP levels in preeclampsia; (3) Full-text availability; and (4) Full-text screening based on PICO criteria. Each outcome is synthesized by a qualitative or narrative approach. The results will be divided into certain points, namely (a) Selection of the studies, (b) Characteristics of the Eligible Studies, (c) Data Extraction of the Eligible Studies, and (d) Risk of Bias Analysis Results.Discussion A systematic review of the role of NT-proBNP as predicting biomarkers for preeclampsia complications will be conducted. This study can help predict the severity, onset, and complication of a pregnant woman with preeclampsia.


Author(s):  
Mara Caroline ◽  
Ryan Bradley ◽  
Mimi Guarneri

The older population is challenging to treat for numerous reasons, including comorbid conditions and increased susceptibility to adverse drug reactions, limiting medical therapy. They are at increased risk for loneliness and depression, which strongly impacts their cardiovascular outcomes, and they also have different values, usually prioritizing quality of life over mortality objectives. Finally, the elderly are underrepresented in cardiovascular clinical trials, thus limiting the applicability of guideline recommendations. This chapter emphasizes the importance of a comprehensive assessment of individual circumstances when assessing cardiovascular health in the elderly population. The chapter focuses on the role of nutrition, resiliency, and exercise for the prevention and treatment of cardiovascular disease. Nutrient deficiencies commonly seen with cardiovascular drugs are also discussed, as well as specific integrative strategies for optimizing dyslipidemia, atrial fibrillation, and heart failure in this population.


2008 ◽  
Vol 4 (2) ◽  
pp. 133-135 ◽  
Author(s):  
Iasmina M Craici ◽  
Steven J Wagner ◽  
Suzanne R Hayman ◽  
Vesna D Garovic

Evaluation of: Bellamy L, Casas JP, Hingorani AD, Williams DJ: Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. Br. Med. J. 335(7627), 974 (2007). Evidence has emerged over the years suggesting that women who develop hypertensive pregnancy disorders, most notably pre-eclampsia, are at an increased risk for cardiovascular disease later in life. In this study, a systematic review and meta-analysis were performed, assessing the future risks of cardiovascular disease, cancer and all-cause mortality in women with a history of pre-eclampsia and eclampsia. Women with a history of pre-eclampsia or eclampsia, compared with women without such a history, had an increased risk for cardiovascular disease, including a fourfold increased risk for hypertension, a twofold increased risk for ischemic heart disease, stroke and deep venous thrombosis, and a 1.5-times higher all-cause mortality. The study suggests that affected women may be eligible for preventive therapies at an earlier age, especially if future studies establish the role of pre-eclampsia as an independent cardiovascular risk factor.


2019 ◽  
Vol 100 ◽  
pp. 103415 ◽  
Author(s):  
Emeline Han ◽  
Rina Yu Chin Quek ◽  
See Mieng Tan ◽  
Shweta R Singh ◽  
Farah Shiraz ◽  
...  

2016 ◽  
Vol 2 (4) ◽  
pp. 237-244 ◽  
Author(s):  
Yousuf Gandapur ◽  
Sina Kianoush ◽  
Heval M. Kelli ◽  
Satish Misra ◽  
Bruno Urrea ◽  
...  

2020 ◽  
Author(s):  
Yuri Henrique da Silva1 ◽  
José Gildo de Moura Monteiro Júnior ◽  
Rosângela Ferreira Frade de Araújo

Abstract Coronavirus disease 2019 (COVID-19) presents as the main cause of death, respiratory and heart failures, especially in the elderly, immunosuppressed, and those with cardiovascular comorbidities. Therefore, a better understanding of these findings is needed. A systematic review was carried out looking for articles published between December 2019 and May 2020 on the MEDLINE / PubMed search platform using the following descriptors: ((((((((("cardiovascular disease") OR ("acute myocardial infarction")) OR ("coronary artery disease")) OR ("acute coronary syndrome")) OR ("atherosclerosis")) OR ("cardiac insufficiency")) OR ("pericarditis")) OR ("myocarditis")) AND ("COVID-19")) OR ("SARS-CoV-2")and considering inclusion and exclusion criteria.40% of patients infected with SARS-CoV-2 had hypertension or other cardiovascular comorbidities, while 27% presented cardiovascular complications, mainly acute cardiac injury, arrhythmia and heart failure. The hypotheses of involvement of an intense inflammatory response, decreased immunity and greater expression of ACE2 in the heart, associated with more severe heart conditions, were discussed in this study. The increase in cardiac and inflammatory markers was associated with worse clinical outcomes and risk of death, confirming the need to evaluate them since admission to the hospital. The 10 articles analyzed presented as a limitation the small number of patients inserted, to the detriment of the pandemic state. We warned about the need for better clinical management of patients with cardiovascular comorbidities, and the importance of including this group among the first to be immunized, aiming at reducing the number of fatal cases due to infection. Studies with greater coverage are needed for a better comprehension of the topics discussed here.


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