Loss of muscle mass in elderly with hip fracture: importance of Body Mass Index and functional capacity. Prospective observational study: PREFISSARC study

Maturitas ◽  
2017 ◽  
Vol 100 ◽  
pp. 200-201
Author(s):  
Vincenzo Malafarina ◽  
Francisco Uriz-Otano ◽  
Concetta Malafarina ◽  
Itziar Abete Goñi ◽  
J. Alfredo Martinez ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Hip Fracture ◽  
Observational Study ◽  
Muscle Mass ◽  
Body Mass ◽  
Functional Capacity ◽  
Prospective Observational Study

scholarly journals Maternal body mass index and oxytocin in augmentation of labour in nulliparous women: a prospective observational study

BMJ Open ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. e044754
Author(s):  
Anna Ramö Isgren ◽  
Preben Kjölhede ◽  
Sara Carlhäll ◽  
Marie Blomberg
Keyword(s):  
Body Mass Index ◽  
Observational Study ◽  
Body Mass ◽  
Infusion Rate ◽  
Maximum Rate ◽  
Prospective Observational Study ◽  
Normal Weight ◽  
Nulliparous Women ◽  
Oxytocin Infusion ◽  
Labour Ward

ObjectiveTo evaluate oxytocin use for augmentation of labour in relation to body mass index (BMI) on admission to the labour ward, focusing on cumulative oxytocin dose and maximum rate of oxytocin infusion during the first stage of labour.DesignProspective observational study.SettingSeven hospitals in Sweden.Participants1097 nulliparous women with singleton cephalic presentation pregnancy, ≥37 weeks of gestation, spontaneous onset of labour and treatment with oxytocin infusion for labour augmentation. The study population was classified into three BMI subgroups on admission to the labour ward: normal weight (18.5–24.9), overweight (25.0–29.9) and obese (≥30.0). The cumulative oxytocin dose was measured from the start of oxytocin infusion until the neonate was born.Primary outcomeCumulative oxytocin dose.Secondary outcomeMaximum rate of oxytocin infusion during the active phase of first stage of labour.ResultsThe mean cumulative oxytocin dose increased in the BMI groups (normal weight 2278 mU, overweight 3108 mU and obese 4082 mU (p<0.0001)). However, when adjusted for the confounders (cervical dilatation when oxytocin infusion was started, fetal birth weight, epidural analgesia), the significant difference was no longer seen. The maximum oxytocin infusion rate during the first stage of labour differed significantly in the BMI groups when adjusted for the confounding factors individually but not when adjusted for all three factors simultaneously. In addition, the maximum oxytocin infusion rate was significantly higher in women with emergency caesarean section compared with women with vaginal delivery.ConclusionsWomen with increasing BMI with augmentation of labour received a higher cumulative oxytocin dose and had a higher maximum oxytocin infusion rate during first stage of labour, however, when adjusted for relevant confounders, the difference was no longer seen. In the future, the guidelines for augmentation of labour with oxytocin infusion might be reconsidered and include modifications related to BMI.

scholarly journals Feasibility of Anesthesiologist-Performed Preoperative Echocardiography for the Prediction of Postinduction Hypotension: A Prospective Observational Study

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Babar Fiza ◽  
Neal Duggal ◽  
Caitlin E. McMillan ◽  
Graciela Mentz ◽  
Michael D. Maile
Keyword(s):  
Body Mass Index ◽  
Observational Study ◽  
General Anesthesia ◽  
Body Mass ◽  
Prospective Observational Study ◽  
Medical Center ◽  
Academic Medical Center ◽  
Vena Cava ◽  
Left Ventricular ◽  
Point Of Care Ultrasound

Purpose. To determine if left ventricular or inferior vena cava (IVC) measurements are easier to obtain on point-of-care ultrasound by anesthesiologists in preoperative patients, and to assess the relationship between preoperative cardiac dimensions and hypotension with the induction of general anesthesia. Methods. This prospective observational study was conducted at a large academic medical center. Sixty-three patients undergoing noncardiac surgeries under general anesthesia were enrolled. Ultrasound examinations were performed by anesthesiologists in the preoperative area. To ensure that hypotension represented both a relative and absolute decrease in blood pressure, both a mean arterial pressure (MAP) < 65 mmHg and a MAP decrease of >30% from preoperative value defined this outcome. Results. Left ventricular measurements were more likely to be acquired than IVC measurements (97% vs. 79%). Subjects without adequate images to assess IVC collapsibility tended to have a higher body mass index (33.6 ± 5.5 vs. 28.5 ± 4.5, p = 0.001 ). While high left ventricular end-diastolic diameter values were associated with a decreased odds of MAP < 65 mmHg (OR: 0.24, 95% CI: 0.07–0.83, p = 0.023 ) or a MAP decrease of >30% from baseline alone (OR: 0.25, 95% CI: 0.07–0.83, p = 0.023 ), the primary endpoint of both relative and absolute hypotension was not associated with preoperative left ventricular dimensions. Conclusions. Preoperative cardiac ultrasound may be a more reliable way for anesthesiologists to assess patients’ volume status compared to ultrasound of the IVC, particularly for patients with a higher body mass index.

scholarly journals Rationale and design of GENEiUS: a prospective observational study on the genetic and environmental determinants of body mass index evolution in Canadian undergraduate students

BMJ Open ◽  
2017 ◽  
Vol 7 (12) ◽  
pp. e019365 ◽  
Author(s):  
Rita E Morassut ◽  
Christine Langlois ◽  
Akram Alyass ◽  
Adeola F Ishola ◽  
Fereshteh T Yazdi ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Observational Study ◽  
Body Mass ◽  
Undergraduate Students ◽  
Body Fat ◽  
Weight Change ◽  
Prospective Observational Study ◽  
Smoking Status ◽  
First Year ◽  
Study Results

IntroductionObesity is a global epidemic and is a risk factor for developing other comorbidities. Young adulthood is a critical period for body weight change and establishing healthy lifestyle behaviours. The ‘Freshman 15’ suggests that undergraduate students gain 15 lbs (6.8 kg) during their first year of university, although evidence estimates a more modest weight gain of approximately 3–5 lbs (1.4–2.3 kg). Previous studies have only investigated weight change in the first year and do not study potential risk factors. Genetic and EnviroNmental Effects on weight in University Students (GENEiUS) is a prospective observational study which will investigate the environmental and biological determinants of weight change in undergraduate students over 4 years.Methods and analysisThe GENEiUS study will recruit 2500 multiethnic undergraduates aged 17–25 years at McMaster University at the start of their first year and will follow them every 6 months for 4 years. Primary outcomes are obesity traits: body mass index, waist circumference, waist-to-hip ratio, body fat mass and body fat percentage. The contribution of well-established and novel genetic variants for obesity traits and heritability values will be derived from whole-genome single-nucleotide polymorphism genotyping arrays. Civil status, age, sex, ethnicity, length of residence in Canada, religiosity, energy intake, physical activity, exercise motivation, electronic screen time, sleep patterns, history of assault, smoking status, alcohol consumption, medication and drug use, stress, impulsivity, body image perception, self-esteem, anxiety, eating disorders and depression will be investigated for their effect on obesity traits. The findings of the GENEiUS study will be used to help design obesity prevention programme in North American universities with multiethnic populations.Ethics and disseminationEthical approval of the study protocol has been obtained from the Hamilton Integrated Research Ethics Board. Study results will be disseminated through scientific publications, scholarly meetings, and collaborative meetings with university administration and student groups.

scholarly journals Comparison of Two Sternal Closure Techniques Based on Risk Factors: A Prospective, Observational Study

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Ali Cemal Duzgun ◽  
Ekin Ilkeli ◽  
Fehmi Katircioglu
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Observational Study ◽  
Body Mass ◽  
Prospective Observational Study ◽  
Closure Technique ◽  
Cable System ◽  
Surgical Technology ◽  
Steel Wires ◽  
Risky Patients

Background. Stainless steel wires are still commonly used as a sternum closure technique. However, it can cause fatal complications due to rupture and dehiscence. It was anticipated that the sternal Cable System (Pioneer Surgical Technology Inc., Marquette, MI, USA) could provide a better sternal fixation and reduce the possible complications. Materials and Method. A total of 100 patients (57 male, 43 female) at high risk of dehiscence were included in this prospective observational study. Among those with EuroSCORE value of 4 and above, patients with chronic lung disease, chronic kidney disease, diabetes mellitus, obesity, smoking, body mass index, advanced age, and resurgery were operated in two separate centers. Standard steel wires ( n : 51) used for sternotomy were compared with the sternal cable ( n : 49). Early and late sternal dehiscence rates were compared in the study. The relationship between risk factors causing dehiscence and both methods was assessed statistically. Results. Early dehiscence rates were 6.4% in those closed with a sternal cable ( n : 3) and 11.8% in those closed with a sternal wire ( n : 6) ( p < 0.05 )). In risky patients, body mass index was the most determining parameter in terms of sternum dehiscence risk. Conclusion. In risky patients, we recommend the sternal cable system as a good and reliable closure technique to achieve a more stable and compact sternum.

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