High-tough hydrogels formed via Schiff base reaction between PAMAM dendrimer and Tetra-PEG and their potential as dual-function delivery systems

Understanding the underlying mechanism of nanomedicine–biomembrane interactions is important for the design and optimization of payload delivery systems.

Download Full-text

All-atomistic molecular dynamics (AA-MD) studies and pharmacokinetic performance of PAMAM-dendrimer-furosemide delivery systems

International Journal of Pharmaceutics ◽

10.1016/j.ijpharm.2018.06.033 ◽

2018 ◽

Vol 547 (1-2) ◽

pp. 545-555 ◽

Cited By ~ 4

Author(s):

Daniel P. Otto ◽

Melgardt M. de Villiers

Keyword(s):

Molecular Dynamics ◽

Pamam Dendrimer ◽

Delivery Systems

Download Full-text

Synthesis and characterization of a PAMAM dendrimer nanocarrier functionalized by HA for targeted gene delivery systems and evaluation in vitro

Journal of Biomaterials Science Polymer Edition ◽

10.1080/09205063.2020.1827921 ◽

2020 ◽

pp. 1-24

Author(s):

Haimei Hu ◽

Han Wang ◽

Shuanghong Liang ◽

Xiaoling Li ◽

Dan Wang

Keyword(s):

Gene Delivery ◽

Pamam Dendrimer ◽

Delivery Systems ◽

Synthesis And Characterization ◽

Targeted Gene Delivery

Download Full-text

Techniques For The Preparation of Tissue Samples Containing Injectable Polymer Microcapsules

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100120242 ◽

1985 ◽

Vol 43 ◽

pp. 710-711

Author(s):

G.E. Visscher ◽

R. L. Robison ◽

G. J. Argentieri

Keyword(s):

Drug Delivery ◽

Drug Delivery Systems ◽

Gastrocnemius Muscle ◽

Degradation Process ◽

Delivery Systems ◽

Tissue Reaction ◽

Electron Microscopic ◽

Tissue Samples ◽

Injectable Polymer ◽

Microscopic Techniques

The use of various bioerodable polymers as drug delivery systems has gained considerable interest in recent years. Among some of the shapes used as delivery systems are films, rods and microcapsules. The work presented here will deal with the techniques we have utilized for the analysis of the tissue reaction to and actual biodegradation of injectable microcapsules. This work has utilized light microscopic (LM), transmission (TEM) and scanning (SEM) electron microscopic techniques. The design of our studies has utilized methodology that would; 1. best characterize the actual degradation process without artifacts introduced by fixation procedures and 2. allow for reproducible results.In our studies, the gastrocnemius muscle of the rat was chosen as the injection site. Prior to the injection of microcapsules the skin above the sites was shaved and tattooed for later recognition and recovery. 1.0 cc syringes were loaded with the desired quantity of microcapsules and the vehicle (0.5% hydroxypropylmethycellulose) drawn up. The syringes were agitated to suspend the microcapsules in the injection vehicle.

Download Full-text

Spin-crossover in an iron(iii) complex showing a broad thermal hysteresis

Dalton Transactions ◽

10.1039/d0dt03610b ◽

2021 ◽

Author(s):

Cyril Rajnák ◽

Romana Mičová ◽

Ján Moncoľ ◽

Ľubor Dlháň ◽

Christoph Krüger ◽

...

Keyword(s):

Schiff Base ◽

Schiff Base Ligand ◽

Spin Crossover ◽

Thermal Hysteresis ◽

Mononuclear Complex ◽

Hysteresis Width ◽

Thermally Induced

A pentadentate Schiff-base ligand 3,5Cl-L2− and NCSe− form a iron(iii) mononuclear complex [Fe(3,5Cl-L)(NCSe)], which shows a thermally induced spin crossover with a broad hysteresis width of 24 K between 123 K (warming) and 99 K (cooling).

Download Full-text