Attaching folic acid on gold nanoparticles using noncovalent interaction via different polyethylene glycol backbones and targeting of cancer cells

2007 ◽  
Vol 3 (3) ◽  
pp. 224-238 ◽  
Author(s):  
Resham Bhattacharya ◽  
Chitta Ranjan Patra ◽  
Alexis Earl ◽  
Shanfeng Wang ◽  
Aaron Katarya ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Folic Acid ◽  
Polyethylene Glycol ◽  
Cancer Cells ◽  
Noncovalent Interaction

Study of the Interaction of Folic Acid-modified Gold Nanorods and Fibrinogen through Microfluidics: Implications on Protein Adsorption, Incorporation and Viability of Cancer Cells

Nanoscale ◽  
2021 ◽  
Author(s):  
Nacaroha Orellana ◽  
Sujey Palma-Florez ◽  
Estefania Torres ◽  
Maria Luisa Cordero ◽  
Valentina Vio ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Folic Acid ◽  
Cancer Cells ◽  
Protein Adsorption ◽  
Gold Nanorods ◽  
Potential Applications

Gold nanoparticles (GNPs) are an attractive nanomaterial for potential applications in therapy and diagnostic due to their capability to direct toward specific sites in the organism. However, when exposed to...

Folic acid-modified methotrexate-conjugated gold nanoparticles as nano-sized trojans for drug delivery to folate receptor-positive cancer cells

2020 ◽  
Vol 31 (35) ◽  
pp. 355101
Author(s):  
Oğuz Yücel ◽  
Aslıhan Şengelen ◽  
Serkan Emik ◽  
Evren Önay-Uçar ◽  
Nazlı Arda ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Folic Acid ◽  
Cancer Cells ◽  
Folate Receptor

scholarly journals Use in vitro of Gold Nanoparticles Functionalized with Folic Acid as a Photothermal Agent on Treatment of HeLa Cells

2018 ◽  
Vol 62 (1) ◽  
Author(s):  
Linda Bertel Garay ◽  
Fernando Martínez Ortega ◽  
Stelia Carolina Méndez-Sanchez
Keyword(s):  
Gold Nanoparticles ◽  
Folic Acid ◽  
Cancer Cells ◽  
Hela Cells ◽  
Near Infrared ◽  
Infrared Light ◽  
Molar Ratio ◽  
Functionalized Gold Nanoparticles ◽  
Dose Dependent

<p>Folic acid (FA) is used as a recognition molecule to achieve selective internalization in cancer cells. Here functionalized gold nanoparticles with folic acid (AuNP-FA) are proposed as suitable therapeutic agents for cervix cancer cells by photothermal damage. The functionalized gold nanoparticles with folic acid were synthesized by mixing hydrogen tetrachloroaurate with folic acid in a molar ratio of 0.56/1 under radiation of mercury lamp (λ<sub>max</sub>=254 nm). HeLa cells were incubated with AuNP-FA during 48 h, then were irradiated and the cytotoxicity was analyzed 12 h after irradiation. The AuNP-FA were dose-dependent cytotoxic under irradiation and not cytotoxic in the absence of radiation. The viability of cancer cells treated with functionalized and non-functionalized gold nanoparticles (AuNPs), with and without near infrared light at 808 nm, was measured by MTT assays. This work provides useful guidance toward the synthesis of biocompatible nanomaterials for biological applications.</p>

Conjugating folic acid to gold nanoparticles through glutathione for targeting and detecting cancer cells

2010 ◽  
Vol 18 (15) ◽  
pp. 5528-5534 ◽  
Author(s):  
Zhaowu Zhang ◽  
Jing Jia ◽  
Youqun Lai ◽  
Yanyan Ma ◽  
Jian Weng ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Folic Acid ◽  
Cancer Cells
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