Usability of a cognitive (Gradior) and physical training program based in new software technologies in patients with mild dementia, mild cognitive impairment and healthy elderly people: Long Lasting Memories preliminary findings

ABSTRACTBackground:The mobile screening test system for screening mild cognitive impairment (mSTS-MCI) was developed for clinical use. However, the clinical usefulness of mSTS-MCI to detect elderly with MCI from those who are cognitively healthy has yet to be validated. Moreover, the comparability between this system and traditional screening tests for MCI has not been evaluated.Objective:The purpose of this study was to examine the validity and reliability of the mSTS-MCI and confirm the cut-off scores to detect MCI.Method:The data were collected from 107 healthy elderly people and 74 elderly people with MCI. Concurrent validity was examined using the Korean version of Montreal Cognitive Assessment (MoCA-K) as a gold standard test, and test–retest reliability was investigated using 30 of the study participants at four-week intervals. The sensitivity, specificity, positive predictive value, and negative predictive value (NPV) were confirmed through Receiver Operating Characteristic (ROC) analysis, and the cut-off scores for elderly people with MCI were identified.Results:Concurrent validity showed statistically significant correlations between the mSTS-MCI and MoCA-K and test–rests reliability indicated high correlation. As a result of screening predictability, the mSTS-MCI had a higher NPV than the MoCA-K.Conclusions:The mSTS-MCI was identified as a system with a high degree of validity and reliability. In addition, the mSTS-MCI showed high screening predictability, indicating it can be used in the clinical field as a screening test system for mild cognitive impairment.

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P2-149: The Mini-Mental State Examination gradient in community healthy elderly subjects, mild cognitive impairment and mild dementia

Alzheimer s & Dementia ◽

10.1016/j.jalz.2010.05.1196 ◽

2010 ◽

Vol 6 ◽

pp. S357-S357

Author(s):

Lívia G. Rodrigues ◽

Ana Luiza Camozzato ◽

Renata Kochhann ◽

Claudia Godinho ◽

Maria Otilia Cerveira ◽

...

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Mental State ◽

Mini Mental State Examination ◽

Elderly Subjects ◽

Mild Dementia ◽

Healthy Elderly ◽

State Examination ◽

Healthy Elderly Subjects

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Effects of commonly prescribed drugs on cognition and mild cognitive impairment in healthy elderly people

Journal of Psychopharmacology ◽

10.1177/0269881119857206 ◽

2019 ◽

Vol 33 (8) ◽

pp. 965-974 ◽

Cited By ~ 1

Author(s):

Teodoro del Ser ◽

María-Ascensión Zea ◽

Meritxell Valentí ◽

Javier Olazarán ◽

Jorge López-Álvarez ◽

...

Keyword(s):

Vitamin D ◽

Cognitive Impairment ◽

Information Processing ◽

Mild Cognitive Impairment ◽

Elderly People ◽

Longitudinal Analyses ◽

Negative Effects ◽

Cross Sectional ◽

Positive Effects ◽

Healthy Elderly

Background:Chronic drug intake has been associated with negative and positive cognitive effects in elderly people, although subjacent conditions may be confounding factors.Aim:To study the effects on cognitive performance of commonly prescribed medications in a cohort of cognitively normal older adults.Methods:Medication intake was recorded during two years in 1087 individuals 70–85 years old, without neurological or psychiatric conditions. The influence of every drug, drug family and therapeutic group on six cognitive scores and on the conversion to mild cognitive impairment over two years was ascertained by cross-sectional and longitudinal analyses controlling for demographic and clinical variables.Results:Small effects of several drugs on information processing were found in cross-sectional analyses but only confirmed for a positive effect of vitamin D in case–control analyses. Longitudinal analyses showed no drug effects on the cognitive slopes. Several hypotensive drugs reduced, whereas bromazepam and glucose lowering drugs increased, the conversion rate to mild cognitive impairment with very small effects ( R2=0.3–1%).Conclusions:Cognitively healthy elderly individuals show minimal negative effects on information processing associated with chronic intake of some drugs probably related to the subjacent condition. Some drugs slightly affect the rate of conversion to mild cognitive impairment. Positive effects of vitamin D, chondroitin, atorvastatin and antihypertensive drugs, and negative effects of antidepressants and benzodiazepines, should be further explored in studies with longer follow-up.

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Feature Extraction of Mild Cognitive Impairment Using a Dual-Task of Drawing and Counting Test

Journal of Advanced Computational Intelligence and Intelligent Informatics ◽

10.20965/jaciii.2019.p0874 ◽

2019 ◽

Vol 23 (5) ◽

pp. 874-882 ◽

Cited By ~ 1

Author(s):

Katsuya Fujiwara ◽

◽

Hidenori Kano ◽

Kazutaka Mitobe

Keyword(s):

Feature Extraction ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Elderly People ◽

Dual Task ◽

Color Change ◽

Information And Communications Technology ◽

Healthy Elderly ◽

Significant Difference ◽

Time Required

From the perspective of preventive care, a monitoring function that detects a decline in cognitive function would be useful as an information and communications technology (ICT) based service for watching over elderly people. We developed a system that evaluates cognitive functioning by simultaneously measuring dual tasks using a tablet computer. The tasks comprised a spiral drawing task and a color change counting task. The objective of this research is feature extraction of mild cognitive impairment (MCI) using this system. To do so, we compared the results of dual task tests for three participant groups: elderly people with suspected MCI, healthy elderly people, and healthy young people. The analyses were based on the amount of time required for drawing each section and the drawing velocity. The results indicate a significant difference between the MCI elders and the other two groups regarding the amount of time required for drawing the section close to the center of the spiral if the difficulty of the test’s sub-task is adjusted.

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Factors Affecting the Instrumental Activities of Daily Living of Elderly People with Mild Cognitive Impairment and Mild Dementia

The Korean Journal of Rehabilitation Nursing ◽

10.7587/kjrehn.2020.140 ◽

2020 ◽

Vol 23 (2) ◽

pp. 140-148

Author(s):

Mee Kyung Shin

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Activities Of Daily Living ◽

Elderly People ◽

Daily Living ◽

Factors Affecting ◽

Mild Dementia ◽

Instrumental Activities

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Faculty Opinions recommendation of Dehydroepiandrosterone (DHEA) supplementation for cognitive function in healthy elderly people.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1046843.496867 ◽

2006 ◽

Author(s):

Argye Hillis

Keyword(s):

Cognitive Function ◽

Elderly People ◽

Healthy Elderly ◽

Healthy Elderly People

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Effects of Balance Shoes on Balance and Postural Stability in the Elderly: A Crossover, Controlled, Randomized Single-Blind Study

Healthcare ◽

10.3390/healthcare9020179 ◽

2021 ◽

Vol 9 (2) ◽

pp. 179

Author(s):

Nicolas Amiez ◽

Carole Cometti ◽

Éric Mouillon ◽

Marie José Teisseire ◽

Pascal Chenut ◽

...

Keyword(s):

Elderly People ◽

Postural Stability ◽

The Elderly ◽

Risk Of Falling ◽

Limits Of Stability ◽

Healthy Elderly ◽

Falling Risk ◽

Familiarization Period ◽

Healthy Elderly People ◽

Single Blind

The risk of falling increases with age. Individuals wearing unadapted shoes present an aggravating risk factor. The objective of this study was to determine the effectiveness of specifically designed balance shoes on balance and postural stability in healthy elderly people compared to that of their usual shoes. In total, 21 healthy individuals aged 65–84 years (76.0 ± 8.0 years) performed balance tests (bipedal with open or closed eyes, unipedal with open eyes, limits of stability, and step cadence) while wearing their (i) personal shoes or (ii) balance shoes (Axis Comfort Development©). Three test sessions were conducted with personal and balance shoes. The first served as the baseline, and the other two were performed after a familiarization period of several days with the personal or balance shoes. The perception of balance shoe efficiency was documented using a questionnaire. The balance shoes significantly improved bipedal balance with closed eyes. Moreover, the familiarization period significantly improved unipedal balance with open eyes. Most subjects felt safer and stabler using balance shoes. The investigated specifically designed balance shoes were effective in elderly individuals in improving postural balance compared to personal shoes. The balance shoes could, therefore, reduce the falling risk in healthy elderly people.

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