Abdominal obesity is associated with arterial stiffness in middle-aged adults

Background and objectives: Several anthropometric and body composition parameters have been linked to arterial stiffness (AS) as a biomarker of cardiovascular disease. However, little is known about which of these closely related factors is more strongly associated with AS. The aim of the present study was to analyze the relationship of different anthropometric and body composition parameters with AS in middle-aged adults. Materials and Methods: This cross-sectional study included 186 middle-aged participants (85 women, 101 men; age = 42.8 ± 12.6 years) evaluated as part of the Healthy UAL study, a population study conducted at the University of Almería with the main purpose of analyzing the etiology and risk factors associated with cardio-metabolic diseases. Anthropometric measures included neck, waist, and hip circumferences, as well as the waist-to-height ratio (WHtr). Bioimpedance-derived parameters included fat-free mass index (FFMI), fat mass index (FMI), and percent of body fat (%BF). AS was measured by pulse wave velocity (PWV). The relationships of interest were examined through stepwise regression analyses in which age and sex were also introduced as potential confounders. Results: Neck circumference (in the anthropometric model; R 2: 0.889; β: age = 0.855, neck = 0.204) and FFMI (in the bio-impedance model; R2: 0.891; β: age = 0.906, FFMI = 0.199) emerged as significant cross-sectional predictors of AS. When all parameters were included together (both anthropometry and bio-impedance), both neck circumference and FFMI appeared again as being significantly associated with AS (R2: 0.894; β: age = 0.882, FFMI = 0.126, neck = 0.093). Conclusion: It was concluded that FFMI and neck circumference are correlated with AS regardless of potential confounders and other anthropometric and bioimpedance-derived parameters in middle-aged adults.

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Relations of Arterial Stiffness With Postural Change in Mean Arterial Pressure in Middle-Aged Adults

Hypertension ◽

10.1161/hypertensionaha.116.08116 ◽

2017 ◽

Vol 69 (4) ◽

pp. 685-690 ◽

Cited By ~ 12

Author(s):

Alyssa Torjesen ◽

Leroy L. Cooper ◽

Jian Rong ◽

Martin G. Larson ◽

Naomi M. Hamburg ◽

...

Keyword(s):

Mean Arterial Pressure ◽

Arterial Stiffness ◽

Arterial Pressure ◽

Postural Change ◽

Middle Aged ◽

Middle Aged Adults ◽

Change In Mean

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Dissociation Between Structural and Functional Changes in Arterial Stiffness After High Intensity Endurance Training in Sedentary Middle-Aged Adults

Medicine & Science in Sports & Exercise ◽

10.1249/01.mss.0000478774.97514.73 ◽

2015 ◽

Vol 47 ◽

pp. 747

Author(s):

Mitchel Samels ◽

Erin Howden ◽

Dean Palmer ◽

Braden Everding ◽

Kara Boyd ◽

...

Keyword(s):

Arterial Stiffness ◽

Endurance Training ◽

High Intensity ◽

Middle Aged ◽

Functional Changes ◽

Middle Aged Adults

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Evaluation of non-invasive arterial stiffness parameters and their relationship with physical activity, anthropometric indices and lipid profiles in healthy middle-aged adults: results of the PERSIAN cohort study

10.22541/au.160960295.57089074/v1 ◽

2021 ◽

Author(s):

Mohammad Nosrati-Oskouie ◽

Sajjad Arefinia ◽

Saeed Eslami Hasan Abadi ◽

Abdolreza Norouzy ◽

Hamed Khedmatgozar ◽

...

Keyword(s):

Physical Activity ◽

Arterial Stiffness ◽

Visceral Fat ◽

Augmentation Index ◽

Lipid Profiles ◽

Fat Free Mass ◽

Middle Aged ◽

Anthropometric Indices ◽

Visceral Fat Area ◽

Middle Aged Adults

Background: Arterial stiffness (AS) indicates the initial stage of cardiovascular disease (CVD), which associated with modifiable and lifestyle risk factors. We aimed to examine the association of AS with anthropometric indices, lipid profiles, and physical activity. Methods: 658 healthy middle-aged adults selected and anthropometric indices (body mass index (BMI), waist circumferences (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), neck circumferences (NC), a body shape index (ABSI), body roundness index (BRI), body-fat mass (BFM), visceral-fat, fat-free mass(FFM), lipid profiles, and PA were measured. Arterial Stiffness measured by carotid-femoral pulse wave velocity (cf-PWV) and central augmentation index (cAIx). Results: Our results show, cf-PWV positively associated with TGs (β = 0.10, p = 0.01) and in anthropometric indices corelated with, WC (β = 0.11, p = 0.02), WHR (β = 0.09, p = 0.03), WHtR (β = 0.1, p = 0.02), and BRI (β = 0.09, p = 0.04). cAIx was independently positive association with cholesterol (β = 0.08, p = 0.03), WC (β = 0.1, p = 0.03), WHR (β = 0.09, p = 0.02), ABSI (β = 0.09, p = 0.01), BRI (β = 0.08, p = 0.05), visceral-fat area (β = 0.09, p = 0.03) and BFM (β = 0.08, p = 0.04) and negatively associated with PA (β = -0.08, p = 0.03). Conclusions: WC, WHR, and BRI were associated with both cf-PWV and cAIx. TGs and WHtR associated with cf-PWV, while cAIx was associated with ABSI, so improving these indices may be helpful to prevent CVD.

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Low-to-Moderate-Intensity Resistance Exercise Effectively Improves Arterial Stiffness in Adults: Evidence From Systematic Review, Meta-Analysis, and Meta-Regression Analysis

Frontiers in Cardiovascular Medicine ◽

10.3389/fcvm.2021.738489 ◽

2021 ◽

Vol 8 ◽

Author(s):

Yong Zhang ◽

Ya-Jun Zhang ◽

Weibing Ye ◽

Mallikarjuna Korivi

Keyword(s):

Systematic Review ◽

Arterial Stiffness ◽

Resistance Exercise ◽

High Intensity ◽

Meta Analysis ◽

Moderate Intensity ◽

Cochrane Library ◽

Middle Aged ◽

Meta Regression ◽

Middle Aged Adults

Background/Purpose: Resistance exercise (RE) is known to improve cardiovascular health, but the role of RE variables on arterial stiffness is inconclusive. In this systematic review and meta-analysis, we investigated the influence of RE and its intensities on arterial stiffness measured as pulse wave velocity (PWV) in young and middle-aged adults.Methods: Web of Science, PubMed/MEDLINE, Scopus, EMBASE, Cochrane Library, ScienceDirect, CINAHL, Wiley Online Library, and Google Scholar were searched for relevant studies. RE trials that reported PWV data, and compared with respective controls were included. The Cochrane Collaboration tool was used to assess the risk of bias.Results: Data were synthesized from a total of 20 studies, involving 981 participants from control (n = 462) and exercise (n = 519) trials. The test for overall effect (pooled outcome) showed RE intervention had no effect on arterial stiffness (SMD = −0.09; 95% CI: −0.32, 0.13; P = 0.42), but risk of heterogeneity (I2) was 64%. Meta-regression results revealed a significant correlation (P = 0.042) between RE intensity and PWV changes. Consequently, the trials were subgrouped into high-intensity and low-to-moderate-intensity to identify the effective RE intensity. Subgroup analysis showed that low-to-moderate-intensity significantly decreased PWV (SMD = −0.34; 95% CI: −0.51, −0.17; P < 0.0001), while high-intensity had no effect (SMD = 0.24; 95% CI: −0.18, 0.67; P = 0.26). When trials separated into young and middle-aged, low-to-moderate-intensity notably decreased PWV in young (SMD = −0.41; 95% CI: −0.77, −0.04; P = 0.03) and middle-aged adults (SMD = −0.32; 95% CI: −0.51, −0.14; P = 0.0007), whereas high-intensity had no effect in both age groups.Conclusions: Our findings demonstrated that RE intensity is the key variable in improving arterial stiffness. Low-to-moderate-intensity can prescribe as an effective non-pharmacological strategy to treat cardiovascular complications in young and middle-aged adults.

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Relationship between abdominal obesity and alcohol drinking pattern in normal-weight, middle-aged adults: the Korea National Health and Nutrition Examination Survey 2008–2013

Public Health Nutrition ◽

10.1017/s1368980017001045 ◽

2017 ◽

Vol 20 (12) ◽

pp. 2192-2200 ◽

Cited By ~ 3

Author(s):

Kye-Yeung Park ◽

Hoon-Ki Park ◽

Hwan-sik Hwang

Keyword(s):

Abdominal Obesity ◽

Health Risks ◽

National Health ◽

Alcohol Drinking ◽

Normal Weight ◽

Drinking Pattern ◽

Nutrition Examination Survey ◽

Middle Aged ◽

Health And Nutrition ◽

Middle Aged Adults

AbstractObjectiveAbdominal obesity is associated with obesity-related health risks regardless of body weight. The present study aimed to determine whether alcohol drinking pattern is associated with abdominal obesity in normal-weight, middle-aged adults.DesignCross-sectional study using complex sampling design analyses.SettingThe Korea National Health and Nutrition Examination Survey, which was conducted from 2008 to 2013.SubjectsNormal-weight participants aged 40–69 years with BMI of 18·5–25·0 kg/m2 (n 11 289, 4491 men and 6798 women) were included. Abdominal obesity was defined as waist circumference ≥90 cm for men or ≥85 cm for women. Alcohol drinking pattern was assessed by self-report on questionnaires.ResultsAmong 11 289 normal-weight participants, 7·9 % (n 379) of men and 7·6 % (n 609) of women had abdominal obesity. Both men and women who consumed a higher quantity of alcohol per drinking occasion had higher odds (OR; 95 % CI) for abdominal obesity compared with individuals who consumed fewer than 2 drinks (1·86; 1·04, 3·32 for ≥10 drinks/typical occasion in men; and 3·28; 1·13, 9·46 in women). Men who binge drink every day had higher odds for abdominal obesity (2·10; 1·21, 3·63). In both sexes, frequency of alcohol drinking was not associated with normal-weight abdominal obesity.ConclusionsOur study showed that the amount of alcohol drinking per occasion influenced abdominal obesity in normal-weight, middle-aged individuals that may have impacted obesity-related health risks. Healthy alcohol drinking habits need to be controlled for prevention of abdominal obesity even among persons with normal weight.

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