Efficacy of omega-3 in treatment of recurrent aphthous stomatitis and improvement of quality of life: a randomized, double-blind, placebo-controlled study

2014 ◽  
Vol 117 (2) ◽  
pp. 191-196 ◽  
Author(s):  
Amr M. El khouli ◽  
Enas Ahmed El-Gendy
Keyword(s):  
Quality Of Life ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Controlled Study ◽  
Omega 3 ◽  
Double Blind ◽  
Double Blind Placebo

scholarly journals Effect of Omega-3 on Recurrent Aphthous Stomatitis and Improvement Quality of Life

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Zahra Hadian ◽  
Ali Akbar Moghadamnia ◽  
Sohrab Kazemi ◽  
Atena Shirzad
Keyword(s):  
Quality Of Life ◽  
Inflammatory Diseases ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Omega 3 ◽  
Mucosal Disease ◽  
Related Quality ◽  
Health Related ◽  
Disease Questionnaire

Objective. Recurrent aphthous stomatitis is one of the most common chronic inflammatory diseases in oral mucosa. Beneficial effects of omega-3 supplements on some inflammatory diseases have been proved. The aim of present study was to evaluate the effect of omega-3 supplements in recurrent aphthous stomatitis management and improve oral health-related quality of life. Methods. In this double-blind clinical trial, 40 patients with minor recurrent aphthous stomatitis were randomly divided into case and control groups. The case group received 1000 mg capsules of omega-3, while the control group received placebo capsules for 6 months. The questionnaires of the ulcer severity score and the chronic oral mucosal disease questionnaire were filled by the patients in three steps, at the baseline session, after 3 months, and after 6 months. The data were analyzed by SPSS 22 software through ANOVA, Mann–Whitney, and chi-square tests. P < 0.05 was considered as significant. Results. In the omega-3 group, the ulcer severity score showed significant reduction by three-month and six-month follow-ups ( P < 0.0001 , P < 0.0001 , respectively). The mean score of the chronic oral mucosal disease questionnaire significantly improved by three-month and six-month follow-ups in the omega-3-receiving group. Conclusion. Use of omega-3 oral supplements decreased the severity of aphthous ulcer and improved oral health-related quality of life.

Effects of dehydroepiandrosterone sulphate (DHEAS) replacement on insulin action and quality of life in hypopituitary females: a double-blind, placebo-controlled study

2012 ◽  
Vol 77 (3) ◽  
pp. 423-429 ◽  
Author(s):  
Claire M. McHenry ◽  
Patrick M. Bell ◽  
Steven J. Hunter ◽  
Christopher J. Thompson ◽  
C. H. Courtney ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Insulin Action ◽  
Controlled Study ◽  
Dehydroepiandrosterone Sulphate ◽  
Double Blind ◽  
Double Blind Placebo
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