Fabrication of micropores on titanium implants using femtosecond laser technology: Perpendicular attachment of connective tissues as a pilot study

2022 ◽  
Vol 148 ◽  
pp. 107624
Author(s):  
Abdalla Abdal-hay ◽  
Reuben Staples ◽  
Abdulaziz Alhazaa ◽  
Benjamin Fournier ◽  
Mahmoud Al-Gawati ◽  
...  
Keyword(s):  
Pilot Study ◽  
Femtosecond Laser ◽  
Titanium Implants ◽  
Connective Tissues ◽  
Laser Technology

Femtosecond laser-induced nanoporous layer for enhanced osteogenesis of titanium implants

2021 ◽  
pp. 112247
Author(s):  
Hao Yao ◽  
Xianrui Zou ◽  
Shijian Zheng ◽  
Yazhou Hu ◽  
Shiliang Zhang ◽  
...  
Keyword(s):  
Femtosecond Laser ◽  
Titanium Implants ◽  
Nanoporous Layer

Femtosecond laser structuring of permeable and resorbable biomaterial

2021 ◽  
Vol 7 (2) ◽  
pp. 713-716
Author(s):  
Swen Grossmann ◽  
Sabine Illner ◽  
Robert Ott ◽  
Grit Rhinow ◽  
Carsten Tautorat ◽  
...  
Keyword(s):  
Femtosecond Laser ◽  
Biomedical Applications ◽  
Mechanical Characteristics ◽  
Membrane Properties ◽  
Fiber Network ◽  
Laser Technology ◽  
Laser Structuring ◽  
Wide Range ◽  
Nanofiber Membranes ◽  
Post Production

Abstract Bioresorbable nanofiber nonwovens with their fascinating properties provide a wide range of potential biomedical applications. Modification of the material enables the adjustment of mechanical and biological characteristics depending on the desired application. Due to the nanosized fiber network, post-production structuring is very challenging. Within this study, we use femtosecond laser technology for structuring permeable and resorbable electrospun poly-L-lactide (PLLA) membranes. We show that this post-production process can be used without disturbing the fiber network near the structured areas. Furthermore, the modification of the water permeability and mechanical characteristics due to the laser structuring was investigated. The results prove femtosecond laser technology to be a promising method for the adjustment of the membrane properties and which in consequence can help to optimize cell adhesion, enable revascularization and open up applications of nanofiber membranes in personalized medicine.

scholarly journals Advances in femtosecond laser technology

2016 ◽  
pp. 697 ◽  
Author(s):  
Thais Maria Pinheiro Callou ◽  
Renato Garcia ◽  
Adriana Mukai ◽  
Samir Bechara ◽  
Natalia Giacomin ◽  
...  
Keyword(s):  
Femtosecond Laser ◽  
Laser Technology

scholarly journals Electrical Impedance of Surface Modified Porous Titanium Implants with Femtosecond Laser

Materials ◽  
2022 ◽  
Vol 15 (2) ◽  
pp. 461
Author(s):  
Paula Navarro ◽  
Alberto Olmo ◽  
Mercè Giner ◽  
Marleny Rodríguez-Albelo ◽  
Ángel Rodríguez ◽  
...  
Keyword(s):  
Cell Culture ◽  
Femtosecond Laser ◽  
Laser Treatment ◽  
Electrical Impedance ◽  
Porous Titanium ◽  
Titanium Implants ◽  
Electrical Impedance Spectroscopy ◽  
Wide Range ◽  
Titanium Surfaces ◽  
Surface Modified

The chemical composition and surface topography of titanium implants are essential to improve implant osseointegration. The present work studies a non-invasive alternative of electrical impedance spectroscopy for the characterization of the macroporosity inherent to the manufacturing process and the effect of the surface treatment with femtosecond laser of titanium discs. Osteoblasts cell culture growths on the titanium surfaces of the laser-treated discs were also studied with this method. The measurements obtained showed that the femtosecond laser treatment of the samples and cell culture produced a significant increase (around 50%) in the absolute value of the electrical impedance module, which could be characterized in a wide range of frequencies (being more relevant at 500 MHz). Results have revealed the potential of this measurement technique, in terms of advantages, in comparison to tiresome and expensive techniques, allowing semi-quantitatively relating impedance measurements to porosity content, as well as detecting the effect of surface modification, generated by laser treatment and cell culture.

Femtosecond Laser Technology in Corneal Refractive Surgery: A Review

2012 ◽  
Vol 28 (12) ◽  
pp. 912-920 ◽  
Author(s):  
George D. Kymionis ◽  
Vardhaman P. Kankariya ◽  
Argyro D. Plaka ◽  
Dan Z. Reinstein
Keyword(s):  
Femtosecond Laser ◽  
Refractive Surgery ◽  
Laser Technology ◽  
Corneal Refractive Surgery

Electrochemical Deposition of Fluoridated Calcium Phosphate Thin Film on Titanium Substrates

2008 ◽  
Vol 47-50 ◽  
pp. 1387-1390 ◽  
Author(s):  
Xiang Ge ◽  
Fu Zeng Ren ◽  
Yang Leng
Keyword(s):  
Thin Film ◽  
Calcium Phosphate ◽  
Dental Implants ◽  
Titanium Substrate ◽  
Titanium Implants ◽  
Connective Tissues ◽  
Percutaneous Device ◽  
Fluorine Ions ◽  
Film Synthesis ◽  
Titanium Substrates

Percutaneous type of orthopedic and dental implants requires not only a good adhesion with bone, but also the ability to form good attachment and seal with connective tissues and skins. Currently, the skin-seal of such implants still remains as a problem to be resolved. Electrochemical processing was used to modify the surface of titanium implants in order to improve the ability of anti-bacteria infection and skin seal around the implants by synthesizing a fluoridated calcium phosphate thin film on titanium substrate. The surface of titanium was cathodically treated in an electrochemical cell. A thin film of about 80 nm thickness was deposited on the titanium surface by controlling the treatment parameters. The dense and gel-like film was composed of calcium phosphate and fluorine ions. Fluorine ion has the anti-bacteria property and could help to improve the skin seal around the percutaneous device. The electrochemical method of fluoridated calcium phosphate thin film synthesis will provide an alternative method for surface treatment of orthopedic and dental implants.

Effect of the variability in implantation depth of intracorneal ring segments using the femtosecond laser technology in corneal ectasia

2019 ◽  
Vol 30 (4) ◽  
pp. 668-675
Author(s):  
Cristina Peris-Martínez ◽  
Cristina Dualde-Beltrán ◽  
Ester Fernández-López ◽  
Maria José Roig-Revert ◽  
Mikhail Hernández-Díaz ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Femtosecond Laser ◽  
Clinical Outcomes ◽  
Relative Depth ◽  
Laser Technology ◽  
Corneal Ectasia ◽  
Implantation Depth ◽  
Prospective Longitudinal ◽  
The Impact

Purpose: To analyze the impact of the depth of implantation of intracorneal ring segments on morphological, biomechanical, and clinical outcomes in ectatic corneas. Methods: This prospective longitudinal study enrolled 40 eyes of 29 patients (age 20–51 years) with corneal ectasia that underwent intracorneal ring segments implantation (KeraRing, Mediphacos). Changes in visual acuity, refraction, corneal tomography, and corneal biomechanics (Ocular Response Analyzer, Reichert) were evaluated during a 6 month follow-up. Likewise, changes in ring segment implantation depth measured by optical coherence tomography (Visante OCT, Carl Zeiss Meditec) were also evaluated. Results: Mean relative depth of implantation was 71.6 ± 5.8%, 71.5 ± 6.5%, and 71.9 ± 6.3% at 1, 3, and 6 months after surgery, respectively (p = 0.827). The difference between the real relative depth of implantation and the theoretical attempted value of 70% was not statistically significant (p = 0.072). Differences in spherical equivalent during the follow-up changed significantly depending on the level of relative depth of implantation (p = 0.036), with an increase of 0.114 D per each 1% increase in relative depth of implantation. Likewise, a decrease of –0.194 D in the steepest keratometric reading was found per each decrease of 1% in relative depth of implantation (p = 0.026). Changes in corneal thickness (p = 0.092) and biomechanics (p = 0.080) were not related to relative depth of implantation. Conclusion: The effect on visual acuity and refraction of intracorneal ring segments when implanted in corneal ectasia is less clinically relevant when the implantation is done at a very deep plane. The variability of the depth of intracorneal ring segments implantation when using femtosecond laser technology is minimal and with no clinically significant effect on clinical outcomes.

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