Comment on “Visceral fat area and cardiometabolic risk: The Kardiovize study”

Abstract Background Visceral fat obesity can be defined quantitatively by abdominal computed tomography, however, the usefulness of measuring visceral fat area to assess the etiology of gastrointestinal reflux disease has not been fully elucidated. Methods A total of 433 healthy subjects aged 40–69 years (234 men, 199 women) were included in the study. The relationship between obesity-related factors (total fat area, visceral fat area, subcutaneous fat area, waist circumference, and body mass index) and the incidence of reflux erosive esophagitis was investigated. Lifestyle factors and stomach conditions relevant to the onset of erosive esophagitis were also analyzed. Results The prevalence of reflux erosive esophagitis was 27.2% (118/433; 106 men, 12 women). Visceral fat area was higher in subjects with erosive esophagitis than in those without (116.6 cm2 vs. 64.9 cm2, respectively). The incidence of erosive esophagitis was higher in subjects with visceral fat obesity (visceral fat area ≥ 100 cm2) than in those without (61.2% vs. 12.8%, respectively). Visceral fat obesity had the highest odds ratio (OR) among obesity-related factors. Multivariate analysis showed that visceral fat area was associated with the incidence of erosive esophagitis (OR = 2.18), indicating that it is an independent risk factor for erosive esophagitis. In addition, daily alcohol intake (OR = 1.54), gastric atrophy open type (OR = 0.29), and never-smoking history (OR = 0.49) were also independently associated with the development of erosive esophagitis. Conclusions Visceral fat obesity is the key risk factor for the development of reflux erosive esophagitis in subjects aged 40–69 years.

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Cut-Off Points of Visceral Fat Area Associated with the Risk of Insulin Resistance in Pediatric Practice

Metabolism ◽

10.1016/j.metabol.2020.154613 ◽

2021 ◽

Vol 116 ◽

pp. 154613

Author(s):

Daria Podchinenova ◽

Julia Samoilova ◽

Oxana Oleynik ◽

Maria Matveeva

Keyword(s):

Insulin Resistance ◽

Visceral Fat ◽

Pediatric Practice ◽

Visceral Fat Area

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Visceral fat area is a better indicator of surgical outcomes after laparoscopic gastrectomy for cancer than the body mass index: a propensity score-matched analysis

Surgical Endoscopy ◽

10.1007/s00464-021-08642-4 ◽

2021 ◽

Author(s):

Yoshiro Imai ◽

Sang-Woong Lee ◽

Masaru Kawai ◽

Keitaro Tashiro ◽

Satoshi Kawashima ◽

...

Keyword(s):

Body Mass Index ◽

Propensity Score ◽

Body Mass ◽

Visceral Fat ◽

Laparoscopic Gastrectomy ◽

Surgical Outcomes ◽

The Body ◽

Visceral Fat Area

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Association between Serum Concentration of Carotenoid and Visceral Fat

Nutrients ◽

10.3390/nu13030912 ◽

2021 ◽

Vol 13 (3) ◽

pp. 912

Author(s):

Mai Matsumoto ◽

Hiroyuki Suganuma ◽

Naoki Ozato ◽

Sunao Shimizu ◽

Mitsuhiro Katashima ◽

...

Keyword(s):

Cardiovascular Diseases ◽

Visceral Fat ◽

Fruits And Vegetables ◽

Beta Carotene ◽

The Body ◽

Healthy Individuals ◽

Health Checkup ◽

Visceral Fat Area ◽

The Relationship ◽

Aomori Prefecture

Consumption of fruits and vegetables rich in carotenoids has been widely reported to prevent cardiovascular diseases. However, the relationship between serum carotenoid concentrations and visceral fat area (VFA), which is considered a better predictor of cardiovascular diseases than the body-mass index (BMI) and waist circumference, remains unclear. Therefore, we examined the relationship in healthy individuals in their 20s or older, stratified by sex and age, to compare the relationship between serum carotenoid concentrations and VFA and BMI. The study was conducted on 805 people, the residents in Hirosaki city, Aomori prefecture, who underwent a health checkup. An inverse relationship between serum carotenoid concentrations and VFA and BMI was observed only in women. In addition, the results were independent of the intake of dietary fiber, which is mainly supplied from vegetables as well as carotenoids. This suggests that consumption of a diet rich in carotenoids (especially lutein and beta-carotene) is associated with lower VFA, which is a good predictor of cardiovascular disease, especially in women. This study is the first to comprehensively evaluate the association between serum carotenoid levels and VFA in healthy individuals.

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Hepatic steatosis in Cushing's syndrome: a radiological assessment using computed tomography

Acta Endocrinologica ◽

10.1530/eje.0.1490543 ◽

2003 ◽

Vol 149 (6) ◽

pp. 543-548 ◽

Cited By ~ 91

Author(s):

AG Rockall ◽

SA Sohaib ◽

D Evans ◽

G Kaltsas ◽

AM Isidori ◽

...

Keyword(s):

Computed Tomography ◽

Hepatic Steatosis ◽

Cushing’S Syndrome ◽

Negative Correlation ◽

Visceral Fat ◽

Subcutaneous Fat ◽

Significant Negative Correlation ◽

Cushing's Syndrome ◽

Abdominal Fat ◽

Visceral Fat Area

OBJECTIVE: Hepatic steatosis may occur in association with insulin resistance and obesity, two features commonly seen in Cushing's syndrome (CS). The aim of this report is to assess the prevalence of hepatic steatosis in patients with active CS using computed tomography (CT) and to identify any associations between hepatic steatosis, endocrine and biochemical variables and body fat distribution. PATIENTS AND MEASUREMENTS: We identified 50 patients with active CS in whom appropriate CT was available to allow measurement of liver and spleen attenuation. In 26 patients, abdominal fat measurements were also available. Serum markers of CS and liver function tests were recorded. RESULTS: Ten of 50 patients had a liver-to-spleen CT attenuation ratio (L/S) of less than 1, indicating hepatic steatosis. There was a significant negative correlation between both liver attenuation and L/S ratio with total abdominal fat area, visceral fat area, the percentage of visceral fat and the visceral to subcutaneous fat ratio; the strongest negative correlation was found between visceral fat area and L/S ratio (r=-0.638, P<0.001, n=26). L/S ratio positively correlated with alkaline phosphatase levels (r=+0.423, P=0.044, n=23) but with no other serum marker of CS activity or liver enzyme. CONCLUSIONS: We have demonstrated hepatic steatosis on CT in 20% of patients with active CS. The presence of hepatic steatosis was significantly correlated with total abdominal fat area and visceral fat area.

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