Lipid biomarkers in Lake Wudalianchi record abrupt environmental changes from the volcanic eruption in 1776

2021 ◽  
pp. 104349
Author(s):  
Yuan Yao ◽  
Yongsong Huang ◽  
Jiaju Zhao ◽  
Li Wang ◽  
Hai Cheng
Keyword(s):  
Volcanic Eruption ◽  
Environmental Changes ◽  
Lipid Biomarkers

Tracking recent environmental changes in Lake Wanghu, China: a multivariate analysis of lipid biomarkers in sediments

Hydrobiologia ◽  
2018 ◽  
Vol 829 (1) ◽  
pp. 281-290 ◽  
Author(s):  
Beibei Shen ◽  
Jinglu Wu ◽  
Jianchao Zhou ◽  
Juanjuan Wang ◽  
Yanhong Yang ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Environmental Changes ◽  
Lipid Biomarkers

scholarly journals Lipokines and Thermogenesis

Endocrinology ◽  
2019 ◽  
Vol 160 (10) ◽  
pp. 2314-2325 ◽  
Author(s):  
Matthew D Lynes ◽  
Sean D Kodani ◽  
Yu-Hua Tseng
Keyword(s):  
Metabolic Disorders ◽  
Environmental Changes ◽  
Excess Energy ◽  
Lipid Biomarkers ◽  
Adaptive Thermogenesis ◽  
Endocrine Hormones ◽  
Beige Adipose Tissue ◽  
Biosynthesis Regulation ◽  
Shed Light ◽  
Catabolic Process

Abstract Adaptive thermogenesis is a catabolic process that consumes energy-storing molecules and expends that energy as heat in response to environmental changes. This process occurs primarily in brown and beige adipose tissue. Thermogenesis is regulated by many factors, including lipid derived paracrine and endocrine hormones called lipokines. Recently, technologic advances for identifying new lipid biomarkers of thermogenic activity have shed light on a diverse set of lipokines that act through different pathways to regulate energy expenditure. In this review, we highlight a few examples of lipokines that regulate thermogenesis. The biosynthesis, regulation, and effects of the thermogenic lipokines in several families are reviewed, including oloeylethanolamine, endocannabinoids, prostaglandin E2, and 12,13-diHOME. These thermogenic lipokines present potential therapeutic targets to combat states of excess energy storage, such as obesity and related metabolic disorders.

Linking transcription, RNA polymerase II elongation and alternative splicing

2020 ◽  
Vol 477 (16) ◽  
pp. 3091-3104 ◽  
Author(s):  
Luciana E. Giono ◽  
Alberto R. Kornblihtt
Keyword(s):  
Gene Expression ◽  
Alternative Splicing ◽  
Rna Polymerase Ii ◽  
Environmental Changes ◽  
Transcription Elongation ◽  
Single Gene ◽  
Regulation Of Gene Expression ◽  
Regulation Of Transcription ◽  
Stepping Stones ◽  
Eukaryotic Transcription

Gene expression is an intricately regulated process that is at the basis of cell differentiation, the maintenance of cell identity and the cellular responses to environmental changes. Alternative splicing, the process by which multiple functionally distinct transcripts are generated from a single gene, is one of the main mechanisms that contribute to expand the coding capacity of genomes and help explain the level of complexity achieved by higher organisms. Eukaryotic transcription is subject to multiple layers of regulation both intrinsic — such as promoter structure — and dynamic, allowing the cell to respond to internal and external signals. Similarly, alternative splicing choices are affected by all of these aspects, mainly through the regulation of transcription elongation, making it a regulatory knob on a par with the regulation of gene expression levels. This review aims to recapitulate some of the history and stepping-stones that led to the paradigms held today about transcription and splicing regulation, with major focus on transcription elongation and its effect on alternative splicing.

Seeking to uncover biology's chemical roots

2019 ◽  
Vol 3 (5) ◽  
pp. 435-443 ◽  
Author(s):  
Addy Pross
Keyword(s):  
Environmental Changes ◽  
Biological Systems ◽  
Significant Development ◽  
The Road ◽  
Physical Chemical ◽  
Systems Chemistry ◽  
Biological World ◽  
Inanimate Matter ◽  
The Origin Of Life ◽  
Opening Up

Despite the considerable advances in molecular biology over the past several decades, the nature of the physical–chemical process by which inanimate matter become transformed into simplest life remains elusive. In this review, we describe recent advances in a relatively new area of chemistry, systems chemistry, which attempts to uncover the physical–chemical principles underlying that remarkable transformation. A significant development has been the discovery that within the space of chemical potentiality there exists a largely unexplored kinetic domain which could be termed dynamic kinetic chemistry. Our analysis suggests that all biological systems and associated sub-systems belong to this distinct domain, thereby facilitating the placement of biological systems within a coherent physical/chemical framework. That discovery offers new insights into the origin of life process, as well as opening the door toward the preparation of active materials able to self-heal, adapt to environmental changes, even communicate, mimicking what transpires routinely in the biological world. The road to simplest proto-life appears to be opening up.

Hubungan Pengetahuan Tentang Manajemen Bencana Dengan Prevention Masyarakat Dalam Menghadapi Bencana Gunung Meletus Pada Kepala Keluarga Di Rt 06/Rw 01 Dusun Puncu Desa Puncu Kecamatan Puncu-Kediri

1970 ◽  
Vol 5 (2) ◽  
pp. 01
Author(s):  
Didit Damayanti ◽  
Pria Wahyu R.G ◽  
Muhanni’ah Muhanni’ah
Keyword(s):  
Disaster Management ◽  
Volcanic Eruption ◽  
Sampling Technique ◽  
P Value ◽  
Cross Sectional ◽  
Head Of Household ◽  
Correlational Research ◽  
Level Of Knowledge ◽  
Independent Variable ◽  
Negative Impacts

Introduction: Disaster management is a dynamic, continual, and integrated process as to increase the qualities of the actions which are relevant to the process of observation and analysis of disaster as well as minimalizing the negative impacts, mitigation, readiness, early warning, immediate emergency, rehabilitation and reconstruction. The aim of this research is to analyse theconnection between disaster management and the prevention of community breakdown in order to face a volcanic eruption for every head of household. Method: The design of this research is correlational research with a cross sectional approach. The demographic group that is used for this research is the head of households in Rt 06/Rw 01 dusun Puncu desa Puncu, by using the purposive sampling technique which has been collected from the sampling of the 33 heads of households. Independent variable is the knowledge of disaster management, and the dependent variable is the prevention of community breakdown in the handling of the disaster. The data has been received by using the questionnaire, and the results have been analysed by using spearman rho test. Result:  As according to the statistics test, it is found that p-value= 0,000 on the significant level (α) = 0,05 and r = 0,752. It is concluded that there is a connection between knowledge and the prevention of community breakdown in handling of the volcanic eruption in Rt 06/Rw 01. This research shows that the level of knowledge within the community about disaster management and prevention in handling volcanic eruption has been increasing. Conclution: This is shown by the capability of the community in mitigating the effects of the disaster. It is hoped that the community will further engage in training education and simulation to reduce the negative impacts of a disaster. The location where the participants resideis Kelud Volcano, and it is therefore hoped that the communities are willing to participate in better handling of any disaster by joining the education training and simulation; Kata kunci : Pengetahuan, Manajemen bencana, Prevention.

Holocene diatom assemblages from Dunderbukhta sediments, West Svalbard

2019 ◽  
pp. 242-245
Author(s):  
Ksenya V. Poleshchuk ◽  
Zinaida V. Pushina ◽  
Sergey R. Verkulich
Keyword(s):  
Environmental Changes ◽  
Ecological Groups ◽  
Diatom Assemblages ◽  
Diatom Analysis ◽  
Diatom Flora ◽  
Sediment Samples ◽  
Ecological Zones ◽  
Middle Holocene ◽  
Temperature Trends

The diatom analysis results of sediment samples from Dunderbukta area (Wedel Jarlsberg Land, West Svalbard) are presented in this paper. The diatom flora consists of four ecological groups, which ratio indicates three ecological zones. These zones show environmental changes of the area in early–middle Holocene that is demonstrating periods of regression and temperature trends.

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