scholarly journals Association and diagnostic value of a novel uric acid index to cardiovascular risk

2021 ◽  
pp. e00247
Author(s):  
Ricardo Rojas-Humpire ◽  
Keila Jauregui-Rodriguez ◽  
Silvana Albornoz ◽  
Percy G. Ruiz Mamani ◽  
Rosmery Gutierrez-Ajalcriña ◽  
...  
2020 ◽  
pp. 5-11
Author(s):  
Yu. V. Zhernakova

A significant number of epidemiological studies have shown that hyperuricemia is highly associated with the risk of developing cardiovascular disease, chronic kidney disease, and diabetes. In this connection, increased attention is required to monitor serum uric acid levels in patients, not only from a rheumatological point of view, but also with regard to reducing cardiovascular and renal risks. This article is a review of studies on the association of hyperuricemia with cardiovascular risk and a new consensus for the management of patients with hyperuricemia and high cardiovascular risk, published in december 2019 by a group of experts of the Russian Medical Society for Arterial Hypertension, which, among other things, includes a management algorithm of this category of patients.


2013 ◽  
Vol 19 (13) ◽  
pp. 2432-2438 ◽  
Author(s):  
Davide Grassi ◽  
Livia Ferri ◽  
Giovambattista Desideri ◽  
Paolo Di Giosia ◽  
Paola Cheli ◽  
...  

2014 ◽  
Vol 81 (5) ◽  
pp. 392-397 ◽  
Author(s):  
Goël Fenech ◽  
Gérald Rajzbaum ◽  
Mikaël Mazighi ◽  
Jacques Blacher

Author(s):  
Gregorio Caimi ◽  
Caterina Urso ◽  
Salvatore Brucculeri ◽  
Corrado Amato ◽  
Rosalia Lo Presti ◽  
...  

BACKGROUND AND OBJECTIVE: we have examined the concentration of serum uric acid and the serum uric acid/creatinine ratio as well as their correlations with the main determinants of the hemorheological profile in a group of subjects with subclinical carotid atherosclerosis. METHODS: we evaluated the concentration of serum uric acid and the serum uric acid/creatine ratio in 43 men and 57 women [median age 66.00 (25)] with subclinical carotid atherosclerosis, subsequently divided according to the number of traditional cardiovascular risk factors and to the insulin resistance degree. RESULTS: serum uric acid, but not the serum uric acid/creatinine ratio, results strongly influenced by the number of cardiovascular risk factors and by the insulin resistance degree. In the whole group and in the subgroups of subclinical carotid atherosclerosis subjects, serum uric acid and serum uric acid/creatinine ratio show significant correlation, besides with whole blood viscosity, with plasma viscosity and erythrocyte aggregation. The influence of the serum uric acid on the erythrocyte aggregability that is a part of the erythrocyte aggregation is to ascribe to the action carried out by serum uric acid on the erythrocyte zeta potential. CONCLUSIONS: it is reasonable to think that the treatment of the asymptomatic or symptomatic hyperuricemia with the urate-lowering therapy that reduces the serum uric acid concentration may reflect on the hemorheological profile which role on the atherosclerotic cardiovascular disease is well known.


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