scholarly journals The analysis of heart rate variability properties and body mass index in representing health quality information

2022 ◽  
Vol 197 ◽  
pp. 135-142
Author(s):  
Izza Alifa Hassya ◽  
Alvin Sahroni ◽  
Aisha Widi Rahayu ◽  
Eki Dipo Laksono
2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Daizhi Yang ◽  
Jinhua Yan ◽  
Hongrong Deng ◽  
Xubin Yang ◽  
Sihui Luo ◽  
...  

Background. To comprehensively assess the effects of metformin added to insulin on metabolic control, insulin sensitivity, and cardiovascular autonomic function in adolescents with type 1 diabetes. Materials and Methods. This was an exploratory, crossover, randomized trial conducted in adolescents with type 1 diabetes aged 12-18 years old. Participants were randomly received metformin (≤1000 mg/d) added to insulin for 24 weeks followed by insulin monotherapy for a subsequent 24 weeks or vice versa. Blood pressure, body mass index, insulin dose, estimated insulin sensitivity, glycated hemoglobin A1c (HbA1c), and lipid profiles were measured, with a 72-hour continuous glucose monitoring and 24-hour Holter monitoring performed at baseline, 24, and 50 weeks for the assessments of glucose variability and heart rate variability. Results. Seventeen patients with mean ± SD age 14.4 ± 2.3   years , body mass index 18.17 ± 1.81   kg / m 2 , median (IQR) diabetes duration 4.50 (3.58, 6.92) years, and HbA1c 9.0% (8.5%, 9.4%) were enrolled. The between-group difference in HbA1c of 0.28% (95% CI -0.39 to 0.95%) was not significant ( P = 0.40 ). Changes in body mass index, insulin dose, blood pressure, lipid profiles, and estimated insulin sensitivity were similar for metformin add-on vs. insulin monotherapy. Glucose variability also did not differ. Compared with insulin monotherapy, metformin add-on significantly increased multiple heart rate variability parameters. Conclusions. Metformin added to insulin did not improve metabolic control or glucose variability in lean/normal-weight adolescents with type 1 diabetes. However, metformin added to insulin significantly increased heart rate variability, suggesting that metformin might improve cardiovascular autonomic function in this population.


2018 ◽  
Vol 33 (1) ◽  
pp. 39-46 ◽  
Author(s):  
M.G. Queiroz ◽  
G. Arsa ◽  
D.A. Rezende ◽  
L.C.J.L. Sousa ◽  
F.R. Oliveira ◽  
...  

2021 ◽  
pp. 101638
Author(s):  
Kathryn E Speer ◽  
Julian Koenig ◽  
Rohan M Telford ◽  
Lisa S Olive ◽  
Jocelyn K Mara ◽  
...  

2017 ◽  
Vol 2 (1) ◽  
Author(s):  
Jamie Michael O'Driscoll ◽  
Adrian Slee ◽  
Rajan Sharma

Background: Chronic kidney disease (CKD) is a silent clinical condition associated with adverse comorbidity and high cardiovascular disease (CVD) risk. An inverse relationship with body mass index (BMI) and mortality has been demonstrated in hemodialysis patients. However, it is unclear if this risk-factor paradox is evident in non-dialysis CKD patients. The aims of this study were to explore the relationship between, nutritional status, markers of inflammation, autonomic and cardiac function with BMI. Longitudinal follow-up explored the relationship between BMI and all-cause mortality. Methods: 211-consecutive CKD patients referred for dobutamine stress echocardiography to detect or exclude myocardial ischemia were recruited. BMI, albumin, C-reactive protein (CRP) and haemoglobin (Hb) were recorded as markers of nutritional and inflammatory status. Left ventricular ejection fraction (LVEF) and heart rate variability (HRV) as an indicator of cardiac function was recorded. All subjects were followed prospectively until November 2014 and study end-point was all-cause mortality. Results: BMI was inversely associated with CKD status. After covariate adjustment, this association remained. During a mean follow-up period of 3.3±0.9 years there were 35 deaths (17%). BMI was inversely associated with all-cause mortality (HR 0.81, 95% CI 0.71-0.9). Other important independent predictors of mortality were heart rate variability (HR 0.98, 95% CI 0.97-0.99), myocardial ischemia (HR 1.37, 95% CI 1.17-1.81), and albumin (HR 0.86, 95% CI 0.81-0.92). Conclusions: The presence of a body mass index paradox exists in non-dialysis CKD patients. This risk-factor paradox was an independent predictor of all-cause mortality and may have significant clinical implications relevant to screening, assessment and treatment and requires further study.


2021 ◽  
Author(s):  
Alejandro Javaloyes ◽  
Daniele Marinazzo ◽  
Daniel Sanabria ◽  
Manuel Moya-Ramón ◽  
José Ramón Lillo-Bevia ◽  
...  

PURPOSE: The COVID-19 crisis also affected elite sport severely, as elite athletes either stopped or drastically reduced their training regimen due to the lack of competitions and the mandatory lockdown. The aim of this study was to test whether heart rate variability was a reliable index of training load, which was dramatically altered due to the mandatory lockdown that occurred as a consequence of the COVID-19. METHODS: Training (volume and intensity) and heart rate variability of sixteen professional male (n = 8; body mass index = 22.2 ± 2.0) and female cyclists (n = 8; body mass index = 20.3 ± 1.1) before (4 weeks), during (7 weeks), and after (4 weeks) the mandatory lockdown in Spain were monitored. RESULTS: Individual analyses showed that the mandatory lockdown caused reliable reductions in training volume in 13 subjects (-96 to -7 % reductions in minutes), that were followed by an increase after the lockdown in all subjects (5 to 270%). In contrast, changes in training load were not homogenous across individuals. Moreover, such changes were not matched by comparable variations in heart rate variability. A mixed model of the heart rate variability as a function of training volume and intensity revealed no significant modulation by these two variables, and subject specific effects on the slope. CONCLUSIONS: In this study, we did not find evidence of association between heart rate variability and training load and/or intensity as many previous reports have suggested, even if training conditions changed dramatically overnight.


Sign in / Sign up

Export Citation Format

Share Document