Corrigendum to “Functions of nonsuicidal self-injury (NSSI): Cross-sectional associations with NSSI duration and longitudinal changes over time and following treatment” [Psychiatry Res. 241 (2016) 83-90]

2018 ◽  
Vol 270 ◽  
pp. 1185
Author(s):  
Sarah E. Victor ◽  
Denise Styer ◽  
Jason J. Washburn
Keyword(s):  
Cross Sectional ◽  
Longitudinal Changes ◽  
Self Injury ◽  
Changes Over Time ◽  
Over Time ◽  
Nonsuicidal Self Injury

Temporal Trends in the Severity and Mortality of Neonatal Hypoxic-Ischemic Encephalopathy in the Era of Hypothermia

Neonatology ◽  
2021 ◽  
pp. 1-8
Author(s):  
Cristina Vega-Del-Val ◽  
Juan Arnaez ◽  
Sonia Caserío ◽  
Elena Pilar Gutiérrez ◽  
Marta Benito ◽  
...  
Keyword(s):  
Temporal Trends ◽  
Cross Sectional Study ◽  
Annual Incidence ◽  
Hypoxic Ischemic Encephalopathy ◽  
Cross Sectional ◽  
Incidence And Mortality ◽  
Changes Over Time ◽  
Ischemic Encephalopathy ◽  
Annual Decline ◽  
Over Time

<b><i>Introduction:</i></b> There is a paucity of studies examining temporal trends in the incidence and mortality of moderate-to-severe hypoxic-ischemic encephalopathy (HIE) during the last decade of therapeutic hypothermia (TH). <b><i>Methods:</i></b> Multicenter cross-sectional study of all infants ≥35 weeks gestational age diagnosed with moderate-to-severe HIE within 6 h of birth in an extensive region of Spain between 2011 and 2019, in order to detect trend changes over time in the (1) annual incidence, (2) severity of neurological and systemic organ involvement, and (3) neonatal death from HIE. <b><i>Results:</i></b> Annual incidence rate of moderate-to-severe HIE was 0.84 (95% confidence interval [CI] 0.7–0.97) per 1,000 births, without trend changes over time (<i>p</i> = 0.8), although the proportion of severe HIE infants showed an average annual decline of 0.86 points (95% CI 0.75–0.98). There were 102 (70%) infants diagnosed with moderate HIE and 44 (30%) with severe HIE. TH was offered to 139/146 (95%) infants. Infants with clinical and/or electrical seizures showed a decreasing trend from 56 to 28% (<i>p</i> = 0.006). Mortality showed a nonstatistically significant decline (<i>p</i> = 0.4), and the severity of systemic damage showed no changes (<i>p</i> = 0.3). Obstetric characteristics remained unchanged, while higher perinatal pH values (<i>p</i> = 0.03) and Apgar scores (<i>p</i> = 0.05), and less need for resuscitation (<i>p</i> = 0.07), were found over time. <b><i>Conclusion:</i></b> The annual incidence of moderate-to-severe HIE has stabilized at around 1 per 1,000 births, with a temporal trend toward a decrease in severe HIE infants and a slight decline of mortality. No association was found between temporal trends and changes in perinatal/obstetric characteristics over time.

Social Support and Nonsuicidal Self-injury among Adolescent Psychiatric Inpatients

2021 ◽  
Author(s):  
John K. Kellerman ◽  
Alexander Millner ◽  
Victoria W. Joyce ◽  
Carol C. Nash ◽  
Ralph Buonopane ◽  
...  
Keyword(s):  
Social Support ◽  
High Risk ◽  
Clinical Sample ◽  
Family Members ◽  
Protective Effects ◽  
Multiple Sources ◽  
Cross Sectional ◽  
Self Injury ◽  
Sources Of Support ◽  
Nonsuicidal Self Injury

Objective: Cross-sectional studies and prospective studies with long follow-up periods (e.g., years) have shown that lower levels of social support are associated with nonsuicidal self-injury (NSSI) among adolescents. This study examined how short-term changes in social support may contribute to NSSI behavior and whether different sources of support (e.g., friends, family members) provide differential protective effects against NSSI. Methods: We examined fluctuations in NSSI and social support perceived from multiple sources among a sample of 118 high-risk adolescents hospitalized for serious self-harm risk. Participants provided daily reports of social support and any self-injurious behavior for the duration of their inpatient treatment (721 total observations, average observations per participant = 6.11). Multi-level models were used to assess variability in social support and how these fluctuations relate to whether or not an individual engages in NSSI. Results: Over one-third of participants reported engaging in NSSI at least once during inpatient hospitalization and self-reported social support varied considerably within-person across sources of support. Support perceived from family members and inpatient unit staff was inversely associated with NSSI, but no relationship was found between NSSI and support from other patients on the unit or friends outside of the unit. Conclusions: These findings suggest that the protective effects of social support for NSSI vary over short periods of time and that support perceived from adults is particularly relevant among this high-risk clinical sample. This study represents an important step in identifying risk factors to improve the detection and prevention of NSSI among adolescent inpatients.

scholarly journals Cross-sectional and prospective associations between sleep regularity and metabolic health in the Hispanic Community Health Study/Study of Latinos

SLEEP ◽  
2020 ◽  
Author(s):  
Josef Fritz ◽  
Andrew J K Phillips ◽  
Larissa C Hunt ◽  
Akram Imam ◽  
Kathryn J Reid ◽  
...  
Keyword(s):  
Community Health ◽  
Cell Function ◽  
Diabetes Risk ◽  
Health Study ◽  
Diabetes Incidence ◽  
Antidiabetic Medication ◽  
Cross Sectional ◽  
Hispanic Community ◽  
Changes Over Time ◽  
Over Time

Abstract Study Objectives Sleep is an emergent, multi-dimensional risk factor for diabetes. Sleep duration, timing, quality, and insomnia have been associated with diabetes risk and glycemic biomarkers, but the role of sleep regularity in the development of metabolic disorders is less clear. Methods We analyzed data from 2107 adults, aged 19–64 years, from the Sueño ancillary study of the Hispanic Community Health Study/Study of Latinos, followed over a mean of 5.7 years. Multivariable-adjusted complex survey regression methods were used to model cross-sectional and prospective associations between the sleep regularity index (SRI) in quartiles (Q1-least regular, Q4-most regular) and diabetes (either laboratory-confirmed or self-reported antidiabetic medication use), baseline levels of insulin resistance (HOMA-IR), beta-cell function (HOMA-β), hemoglobin A1c (HbA1c), and their changes over time. Results Cross-sectionally, lower SRI was associated with higher odds of diabetes (odds ratio [OR]Q1 vs. Q4 = 1.64, 95% CI: 0.98–2.74, ORQ2 vs. Q4 = 1.12, 95% CI: 0.70–1.81, ORQ3 vs. Q4 = 1.00, 95% CI: 0.62–1.62, ptrend = 0.023). The SRI effect was more pronounced in older (aged ≥ 45 years) adults (ORQ1 vs. Q4 = 1.88, 95% CI: 1.14–3.12, pinteraction = 0.060) compared to younger ones. No statistically significant associations were found between SRI and diabetes incidence, as well as baseline HOMA-IR, HOMA-β, and HbA1c values, or their changes over time among adults not taking antidiabetic medication. Conclusions Our results suggest that sleep regularity represents another sleep dimension relevant for diabetes risk. Further research is needed to elucidate the relative contribution of sleep regularity to metabolic dysregulation and pathophysiology.

Trajectories of major depression disorders: A systematic review of longitudinal neuroimaging findings

2016 ◽  
Vol 51 (5) ◽  
pp. 441-454 ◽  
Author(s):  
Katharina Dohm ◽  
Ronny Redlich ◽  
Pienie Zwitserlood ◽  
Udo Dannlowski
Keyword(s):  
Systematic Review ◽  
Major Depression ◽  
Longitudinal Studies ◽  
Time Window ◽  
Mood State ◽  
Sample Sizes ◽  
Cross Sectional ◽  
Changes Over Time ◽  
Over Time ◽  
Course Of Depression

Objective: Structural and functional brain alterations in major depression disorder (MDD) are well studied in cross-sectional designs, but little is known about the causality between onset and course of depression on the one hand, and neurobiological changes over time on the other. To explore the direction of causality, longitudinal studies with a long time window (preferably years) are needed, but only few have been undertaken so far. This article reviews all prospective neuroimaging studies in MDD patients currently available and provides a critical discussion of methodological challenges involved in the investigation of the causal relationship between brain alterations and the course of MDD. Method: We conducted a systematic review of studies published before September 2015, to identify structural magnetic resonance imaging (MRI) studies that assess the relation between neuronal alterations and MDD in longitudinal (⩾1 year) designs. Results: Only 15 studies meeting minimal standards were identified. An analysis of these longitudinal data showed a large heterogeneity between studies regarding design, samples, imaging methods, spatial restrictions and, consequently, results. There was a strong relationship between brain-volume outcomes and the current mood state, whereas longitudinal studies failed to clarify the influence of pre-existing brain changes on depressive outcome. Conclusion: So far, available longitudinal studies cannot resolve the causality between the course of depression and neurobiological changes over time. Future studies should combine high methodological standards with large sample sizes. Cooperation in multi-center studies is indispensable to attain sufficient sample sizes, and should allow careful assessment of possible confounders.

scholarly journals Death Anxiety and Pain Catastrophizing Among Male Inmates With Nonsuicidal Self-Injury Behavior: A Comparative Study

2015 ◽  
Vol 11 (4) ◽  
pp. 1174-1181 ◽  
Author(s):  
Violeta Enea ◽  
Ion Dafinoiu ◽  
Georgiana Bogdan ◽  
Carmen Matei
Keyword(s):  
Comparative Study ◽  
Behavior Management ◽  
Death Anxiety ◽  
Pain Catastrophizing ◽  
Cross Sectional ◽  
Dissociative Experiences ◽  
Self Injury ◽  
Management Plans ◽  
Male Inmates ◽  
Nonsuicidal Self Injury

Most of the studies concerning nonsuicidal self-injury behaviors of persons deprived of liberty were on female participants. This cross-sectional comparative study compared the levels of death anxiety, pain catastrophizing, dissociative experiences, and state-trait anger among male inmates with nonsuicidal self-injury behaviors and noninjuring controls. The results indicated high levels of death anxiety, dissociation, and pain catastrophizing in both groups of participants and the absence of significant differences between the groups. The implications of the results suggest the need of taking into consideration these variables in the behavior management plans used with inmates who engage in self-injurious behavior.

scholarly journals Institutional logic and scholars' reactions to performance measurement in universities

2021 ◽  
Vol 34 (9) ◽  
pp. 104-130
Author(s):  
Kirsi-Mari Kallio ◽  
Tomi J. Kallio ◽  
Giuseppe Grossi ◽  
Janne Engblom
Keyword(s):  
Performance Measurement ◽  
Organizational Level ◽  
Institutional Logic ◽  
Institutional Work ◽  
Cross Sectional ◽  
Content Type ◽  
Measurement Systems ◽  
Performance Measurement Systems ◽  
Changes Over Time ◽  
Over Time

PurposeEmploying institutional logic and institutional work as its theoretical framework, this study analyzes scholars' reactions to performance measurement systems in academia.Design/methodology/approachLarge datasets were collected over time, combining both quantitative and qualitative elements. The data were gathered from a two-wave survey in 2010 (966 respondents) and 2015 (672 respondents), conducted among scholars performing teaching- and research-oriented tasks in three Finnish universities.FindingsThe analysis showed statistically significant changes over time in the ways that the respondents were positioned in three major groups influenced by different institutional logics. This study contributes to the international debate on institutional change in universities by showing that in Finnish universities, emerging business logics and existing professional logics can co-exist and be blended among a growing group of academics. The analysis of qualitative open-ended answers suggests that performance measurement systems have led to changes in institutional logic, which have influenced the scholars participating in institutional work at the microlevel in academia.Social implicationsWhile most scholars remain critical of performance measurement systems in universities, the fact that many academics are adapting to performance measurement systems highlights significant changes that are generally occurring in academia.Originality/valueWhile most extant studies have focused on field- and organizational-level analyses, this study focuses on understanding how the adoption of performance measurement systems affects institutional logic and institutional work at the microlevel. Moreover, the study's cross-sectional research setting increases society's understanding of institutional evolution in academia.

scholarly journals Multimodal assessment of sustained threat in adolescents with nonsuicidal self-injury

2021 ◽  
pp. 1-19
Author(s):  
Zeynep Başgöze ◽  
Salahudeen A. Mirza ◽  
Thanharat Silamongkol ◽  
Dawson Hill ◽  
Conner Falke ◽  
...  
Keyword(s):  
Suicide Attempt ◽  
Social Stress ◽  
Stress Test ◽  
Trier Social Stress Test ◽  
Resting State Functional Connectivity ◽  
Cross Sectional ◽  
Amygdala Activation ◽  
Self Injury ◽  
Cross Sectional Design ◽  
Nonsuicidal Self Injury

Abstract Nonsuicidal self-injury (NSSI) is a common but poorly understood phenomenon in adolescents. This study examined the Sustained Threat domain in female adolescents with a continuum of NSSI severity (N = 142). Across NSSI lifetime frequency and NSSI severity groups (No + Mild NSSI, Moderate NSSI, Severe NSSI), we examined physiological, self-reported and observed stress during the Trier Social Stress Test; amygdala volume; amygdala responses to threat stimuli; and resting-state functional connectivity (RSFC) between amygdala and medial prefrontal cortex (mPFC). Severe NSSI showed a blunted pattern of cortisol response, despite elevated reported and observed stress during TSST. Severe NSSI showed lower amygdala–mPFC RSFC; follow-up analyses suggested that this was more pronounced in those with a history of suicide attempt for both moderate and severe NSSI. Moderate NSSI showed elevated right amygdala activation to threat; multiple regressions showed that, when considered together with low amygdala–mPFC RSFC, higher right but lower left amygdala activation predicted NSSI severity. Patterns of interrelationships among Sustained Threat measures varied substantially across NSSI severity groups, and further by suicide attempt history. Study limitations include the cross-sectional design, missing data, and sampling biases. Our findings highlight the value of multilevel approaches in understanding the complexity of neurobiological mechanisms in adolescent NSSI.

apoE4 allele and the natural history of cardiovascular risk factors

2005 ◽  
Vol 289 (2) ◽  
pp. E322-E327 ◽  
Author(s):  
Angelo Scuteri ◽  
Samer S. Najjar ◽  
Denis Muller ◽  
Reubin Andres ◽  
Christopher H. Morrell ◽  
...  
Keyword(s):  
Risk Factors ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Hdl Cholesterol ◽  
Repeated Measurements ◽  
Longitudinal Changes ◽  
Apoe4 Allele ◽  
Fasting Plasma ◽  
Changes Over Time ◽  
Over Time

The aims of the present study were to compare the longitudinal changes in traditional cardiovascular (CV) risk factors (blood pressure, BMI, total and HDL-cholesterol, triglycerides, and blood glucose) in men with and without the apolipoprotein (apo)E4 allele. Three hundred six men from the Baltimore Longitudinal Study of Aging, ranging in age from 20 to 92 yr, were studied. Repeated measurements of CV risk factors were performed over a median follow-up time of 7 yr (maximum 14.3 yr) for men. Longitudinal changes in these CV risk factors were analyzed by linear mixed-effects models. The prevalence of the apoE4 allele was 25.5%. apoE4 was independently associated with accelerated changes over time in fasting plasma glucose (+9.5% vs. no change in those without apoE4 in the 6th age-decade over 10 yr). No significant effect of apoE4 on longitudinal changes in total or HDL-cholesterol, triglycerides, or blood pressures was observed. In conclusion, apoE4 influences fasting plasma glucose and its changes over time. This could explain, in part, the increased CV risk associated with the apoE4 genotype observed in men.

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