PTSD symptoms predict waking salivary cortisol levels in police officers

2005 ◽  
Vol 30 (4) ◽  
pp. 373-381 ◽  
Author(s):  
Thomas C. Neylan ◽  
Alain Brunet ◽  
Nnamdi Pole ◽  
Suzanne R. Best ◽  
Thomas J. Metzler ◽  
...  
Author(s):  
Juliana Petri Tavares ◽  
Liana Lautert ◽  
Tânia Solange Bosi de Souza Magnago ◽  
Angélica Rosat Consiglio ◽  
Daiane Dal Pai

Abstract Objective: to analyze the relationship between psychosocial stress dimensions and salivary cortisol in military police officers. Method: cross-sectional and analytical study with 134 military police officers. The Effort-Reward Imbalance (ERI) Model scale has been used to assess psychosocial stress. Salivary cortisol was collected in three samples. The following tests were used: Student's t-test, Mann-Whitney, ANOVA, Bonferroni, Kruskal-Wallis and Dunn. Pearson and Spearman correlation methods were used, as well as multiple linear regression. Cortisol at night showed an ascending statistical association with the psychosocial reward (p=0.004) and a descending association with the effort-impairment scores (p=0.017). Being part of the Special Tactical Operations Group (GATE) and the diastolic blood pressure explained 13.5% of the variation in cortisol levels on waking up. The sectors GATE, Special Patrol of the Elite Squad of the Military Police and Motorcyclists explained 21.9% of the variation in cortisol levels 30-minute after awakening. The variables GATE sector and Effort Dimension explained 27.7% of the variation in cortisol levels at night. Conclusion: it was evidenced that salivary cortisol variation was influenced by individual, labor and psychosocial variables.


2009 ◽  
Author(s):  
Jerald Gardner ◽  
Thomas Metzler ◽  
Clare Henn-Haase ◽  
Janie Jun ◽  
Charles Marmar

2009 ◽  
Author(s):  
Brigitte Apfel ◽  
Sabra S. Inslicht ◽  
Shannon McCaslin ◽  
Thomas Metzler ◽  
Thomas Neylan ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Levente Kovács ◽  
Fruzsina Luca Kézér ◽  
Szilárd Bodó ◽  
Ferenc Ruff ◽  
Rupert Palme ◽  
...  

AbstractThe intensity and the magnitude of saliva cortisol responses were investigated during the first 48 h following birth in newborn dairy calves which underwent normal (eutocic, EUT, n = 88) and difficult (dystocic, DYS, n = 70) calvings. The effects of parity and body condition of the dam, the duration of parturition, the time spent licking the calf, the sex and birth weight of the calf were also analyzed. Neonatal salivary cortisol concentrations were influenced neither by factors related to the dam (parity, body condition) nor the calf (sex, birth weight). The duration of parturition and the time spent licking the calf also had no effect on salivary cortisol levels. Salivary cortisol concentrations increased rapidly after delivery in both groups to reach their peak levels at 45 and 60 min after delivery in EUT and DYS calves, respectively supporting that the birth process means considerable stress for calves and the immediate postnatal period also appears to be stressful for newborn calves. DYS calves exhibited higher salivary cortisol concentrations compared to EUT ones for 0 (P = 0.022), 15 (P = 0.016), 30 (P = 0.007), 45 (P = 0.003), 60 (P = 0.001) and 120 min (P = 0.001), and for 24 h (P = 0.040), respectively. Peak levels of salivary cortisol and the cortisol release into saliva calculated as AUC were higher in DYS than in EUT calves for the 48-h of the sampling period (P = 0.009 and P = 0.003, respectively). The greater magnitude of saliva cortisol levels in DYS calves compared to EUT ones suggest that difficult parturition means severe stress for bovine neonates and salivary cortisol could be an opportunity for non-invasive assessment of stress during the early neonatal period in cattle.


Author(s):  
Elena Gonzalez Rodriguez ◽  
Pedro Marques-Vidal ◽  
Bérengère Aubry-Rozier ◽  
Georgios Papadakis ◽  
Martin Preisig ◽  
...  

AbstractSarcopenia, similar to hypercortisolism, is characterized by loss of muscle mass and strength. Cortisol circadian rhythm changes with aging (blunted late-day nadir values) were suggested to contribute to this decline. We aimed to explore the relationship between diurnal salivary cortisol values and sarcopenia diagnosis and its components in postmenopausal women. This is a cross-sectional study within the OsteoLaus population-based cohort in Lausanne (Switzerland). Participants had a body composition assessment by dual X-ray absorptiometry (DXA), a grip strength (GS) measure, and salivary cortisol measures (at awakening, 30 min thereafter, 11 AM (sc-11AM) and 8 PM (sc-8PM)). Associations between salivary cortisol and sarcopenia diagnosed by six different criteria (based on appendicular lean mass (ALM) assessed by DXA, and muscle strength by GS), and its components, were analyzed. 471 women aged > 50 years (63.0 ± 7.5) were included. Various definitions identified different participants as sarcopenic, who consistently presented higher salivary cortisol at 11 AM and/or 8 PM. There were no associations between salivary cortisol levels and ALM measures, either absolute or after correction to height squared (ALM index) or body mass index. GS was inversely correlated to sc-11AM (r = − 0.153, p < 0.001) and sc-8PM (r = − 0.118, p = 0.002). Each 10 nmol/l increase of sc-11AM, respectively sc-8PM, was associated with a GS decrease of 1.758 (SE 0.472) kg, respectively 2.929 (SE 1.115) kg. In postmenopausal women, sarcopenia is associated with higher salivary cortisol levels at 11 AM and 8 PM. An increase of daily free cortisol levels in the physiological range could participate to sarcopenia development by decreasing muscle function in postmenopausal women.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Eleonora Iob ◽  
Jessie R. Baldwin ◽  
Robert Plomin ◽  
Andrew Steptoe

AbstractDysregulated hypothalamic–pituitary–adrenal (HPA)-axis function might underlie the relationship between adverse childhood experiences (ACEs) and depression. However, limited research has examined the possible mediating role of the HPA-axis among young people using longitudinal data. Moreover, it remains unclear whether genetic influences could contribute to these associations. Participants were 290 children from the Twins Early Development Study. ACEs were assessed from age 3–11 years. We calculated a cumulative risk score and also derived different ACEs clusters using factor analysis and latent class analysis. HPA-axis activity was indexed by daytime salivary cortisol at age 11. Depressive symptoms were ascertained at age 21. Genetic liability to altered cortisol levels and elevated depressive symptoms was measured using a twin-based method. We performed causal mediation analysis with mixed-effects regression models. The results showed that ACEs cumulative exposure (b = −0.20, p = 0.03), bullying (b = −0.61, p = 0.01), and emotional abuse (b = −0.84, p = 0.02) were associated with lower cortisol levels at age 11. Among participants exposed to multiple ACEs, lower cortisol was related to higher depressive symptoms at age 21 (b = −0.56, p = 0.05). Lower cortisol levels mediated around 10–20% of the total associations of ACEs cumulative exposure, bullying, and dysfunctional parenting/emotional abuse with higher depressive symptoms. Genetic factors contributed to these associations, but the mediation effects of cortisol in the associations of ACEs cumulative exposure (b = 0.16 [0.02–0.34]) and bullying (b = 0.18 [0.01–0.43]) remained when genetic confounding was accounted for. In conclusion, ACEs were linked to elevated depressive symptoms in early adulthood partly through lower cortisol levels in early adolescence, and these relationships were independent of genetic confounding.


2021 ◽  
Vol 148 ◽  
pp. 104404
Author(s):  
Dulce E. Alarcón-Yaquetto ◽  
Jean P. Tincopa ◽  
Daniel Guillén-Pinto ◽  
Nataly Bailon ◽  
César P. Cárcamo

2007 ◽  
Vol 164 (4) ◽  
pp. 617-621 ◽  
Author(s):  
Zola N. Mannie ◽  
Catherine J. Harmer ◽  
Philip J. Cowen

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Genevieve Arsenault-Lapierre ◽  
Victor Whitehead ◽  
Sonia Lupien ◽  
Howard Chertkow

Anosognosia, or unawareness of one’s own cognitive deficits, may cause issues when measuring perceived stress and cortisol levels in Alzheimer’s disease (AD) and Mild Cognitive Impairment (MCI). The goal of this study was to examine the effects of anosognosia on perceived stress and salivary cortisol levels in normal elderly (NE) adults, MCI individuals, newly diagnosed AD patients, and long-lasting AD patients, suspected to show more anosognosia. An anosognosia index for perceived stress was computed by subtracting the score on the Perceived Stress Scale measured in the participants and their relative. Cortisol levels were measured four times a day over two nonconsecutive days. Greater anosognosia for dementia correlated with greater anosognosia for perceived stress in the group as a whole. However, no correlation between cortisol levels and either anosognosia for dementia or perceived stress was observed. Our results suggest that measuring perceived stress in AD patients may be influenced by anosognosia.


Sign in / Sign up

Export Citation Format

Share Document