scholarly journals A hybrid recommendation model for successful R&D collaboration: Mixing machine learning and discriminant analysis

2021 ◽  
Vol 170 ◽  
pp. 120871
Author(s):  
Seung-Pyo Jun ◽  
Hyoung Sun Yoo ◽  
Jeena Hwang
Keyword(s):  
Machine Learning ◽  
Discriminant Analysis ◽  
Hybrid Recommendation

scholarly journals Dimension Reduction for Objects Composed of Vector Sets

2017 ◽  
Vol 27 (1) ◽  
pp. 169-180 ◽  
Author(s):  
Marton Szemenyei ◽  
Ferenc Vajda
Keyword(s):  
Machine Learning ◽  
Data Mining ◽  
Feature Selection ◽  
Discriminant Analysis ◽  
Probability Distribution ◽  
Dimension Reduction ◽  
Pose Estimation ◽  
Real World ◽  
Single Object ◽  
Real World Datasets

Abstract Dimension reduction and feature selection are fundamental tools for machine learning and data mining. Most existing methods, however, assume that objects are represented by a single vectorial descriptor. In reality, some description methods assign unordered sets or graphs of vectors to a single object, where each vector is assumed to have the same number of dimensions, but is drawn from a different probability distribution. Moreover, some applications (such as pose estimation) may require the recognition of individual vectors (nodes) of an object. In such cases it is essential that the nodes within a single object remain distinguishable after dimension reduction. In this paper we propose new discriminant analysis methods that are able to satisfy two criteria at the same time: separating between classes and between the nodes of an object instance. We analyze and evaluate our methods on several different synthetic and real-world datasets.

Tremor Identification Using Machine Learning in Parkinson's Disease

2019 ◽  
pp. 128-151
Author(s):  
Angana Saikia ◽  
Vinayak Majhi ◽  
Masaraf Hussain ◽  
Sudip Paul ◽  
Amitava Datta
Keyword(s):  
Machine Learning ◽  
Parkinson’S Disease ◽  
Support Vector Machine ◽  
Parkinson's Disease ◽  
Discriminant Analysis ◽  
Learning Algorithms ◽  
The Body ◽  
Machine Learning Algorithms ◽  
Support Vector

Tremor is an involuntary quivering movement or shake. Characteristically occurring at rest, the classic slow, rhythmic tremor of Parkinson's disease (PD) typically starts in one hand, foot, or leg and can eventually affect both sides of the body. The resting tremor of PD can also occur in the jaw, chin, mouth, or tongue. Loss of dopamine leads to the symptoms of Parkinson's disease and may include a tremor. For some people, a tremor might be the first symptom of PD. Various studies have proposed measurable technologies and the analysis of the characteristics of Parkinsonian tremors using different techniques. Various machine-learning algorithms such as a support vector machine (SVM) with three kernels, a discriminant analysis, a random forest, and a kNN algorithm are also used to classify and identify various kinds of tremors. This chapter focuses on an in-depth review on identification and classification of various Parkinsonian tremors using machine learning algorithms.

Introduction and Implementation of Machine Learning Algorithms in R

2019 ◽  
pp. 126-147
Author(s):  
S. R. Mani Sekhar ◽  
G. M. Siddesh
Keyword(s):  
Machine Learning ◽  
Neural Networks ◽  
Support Vector Machine ◽  
Discriminant Analysis ◽  
Computer Science ◽  
Learning Algorithms ◽  
Machine Learning Algorithms ◽  
Support Vector ◽  
Linear Discriminant ◽  
The Given

Machine learning is one of the important areas in the field of computer science. It helps to provide an optimized solution for the real-world problems by using past knowledge or previous experience data. There are different types of machine learning algorithms present in computer science. This chapter provides the overview of some selected machine learning algorithms such as linear regression, linear discriminant analysis, support vector machine, naive Bayes classifier, neural networks, and decision trees. Each of these methods is illustrated in detail with an example and R code, which in turn assists the reader to generate their own solutions for the given problems.

Classification of Encryption Algorithms using Fisher’s Discriminant Analysis

2016 ◽  
Vol 67 (1) ◽  
pp. 59 ◽  
Author(s):  
Prabhat Kumar Ray ◽  
Shrikant Ojha ◽  
Bimal Kumar Roy ◽  
Ayanendranath Basu
Keyword(s):  
Machine Learning ◽  
Discriminant Analysis ◽  
Block Cipher ◽  
Good Classification ◽  
Finite Set ◽  
Encryption Algorithms ◽  
Fisher’S Discriminant Analysis

<p>Fisher’s Discriminant Analysis (FDA) is a method used in statistics and machine learning which can often lead to good classification between several populations by maximizing the separation between the populations. We will present some applications of FDA that discriminate between cipher texts in terms of a finite set of encryption algorithms. Specifically, we use ten algorithms, five each of stream and block cipher types. Our results display good classification with some of the features. In the present case we have little in terms of an existing standard; however, our limited study clearly shows that further exploration of this issue could be worthwhile.</p>

scholarly journals Sex estimation in cranial remains: A comparison of machine learning and discriminant analysis in Italian populations

2020 ◽  
Author(s):  
A Pozzi ◽  
C Raffone ◽  
MG Belcastro ◽  
TL Camilleri-Carter
Keyword(s):  
Machine Learning ◽  
Discriminant Analysis ◽  
Linear Discriminant Analysis ◽  
Foramen Magnum ◽  
Sex Estimation ◽  
Learning Models ◽  
Linear Discriminant ◽  
Machine Learning Methods ◽  
Cranial Measurements ◽  
Machine Learning Models

ABSTRACTObjectivesUsing cranial measurements in two Italian populations, we compare machine learning methods to the more traditional method of linear discriminant analysis in estimating sex. We use crania in sex estimation because it is useful especially when remains are fragmented or displaced, and the cranium may be the only remains found.Materials and MethodsUsing the machine learning methods of decision tree learning, support-vector machines, k-nearest neighbor algorithm, and ensemble methods we estimate the sex of two populations: Samples from Bologna and samples from the island of Sardinia. We used two datasets, one containing 17 cranial measurements, and one measuring the foramen magnum.Results and DiscussionOur results indicate that machine learning models produce similar results to linear discriminant analysis, but in some cases machine learning produces more consistent accuracy between the sexes. Our study shows that sex can be accurately predicted (> 80%) in Italian populations using the cranial measurements we gathered, except for the foramen magnum, which shows a level of accuracy of ∼70% accurate which is on par with previous geometric morphometrics studies using crania in sex estimation. We also find that our trained machine learning models produce population-specific results; we see that Italian crania are sexually dimorphic, but the features that are important to this dimorphism differ between the populations.

scholarly journals Single Cell Raman Spectroscopy to Identify Different Stages of Proliferating Human Hepatocytes for Cell Therapy

2021 ◽  
Author(s):  
Chen Ma ◽  
Ludi Zhang ◽  
Ting He ◽  
Huiying Cao ◽  
Chenhui Ma ◽  
...  
Keyword(s):  
Machine Learning ◽  
Raman Spectroscopy ◽  
Discriminant Analysis ◽  
Cell Therapy ◽  
Linear Discriminant Analysis ◽  
Learning Model ◽  
Human Hepatocytes ◽  
Linear Discriminant ◽  
Analytical Technique ◽  
Machine Learning Model

Abstract Background: Cell therapy provides hope for treatment of advanced liver failure. Proliferating human hepatocytes (ProliHHs) were derived from primary human hepatocytes (PHH) and as potential alternative for cell therapy in liver diseases. Due to the continuous decline of mature hepatic genes and increase of progenitor like genes during ProliHHs expanding, it is challenge to monitor the critical changes of the whole process. Raman microspectroscopy is a noninvasive, label free analytical technique with high sensitivity capacity. In this study, we evaluated the potential and feasibility to identify ProliHHs from PHH with Raman spectroscopy.Methods: Raman spectra were collected at least 600 single spectrum for PHH and ProliHHs at different stages (Passage 1 to Passage 4). Linear discriminant analysis and a two-layer machine learning model were used to analyze the Raman spectroscopy data. Significant differences in Raman bands were validated by the associated conventional kits.Results: Linear discriminant analysis successfully classified ProliHHs at different stages and PHH. A two-layer machine learning model was established and the overall accuracy was at 84.6%. Significant differences in Raman bands have been found within different ProliHHs cell groups, especially changes at 1003 cm-1, 1206 cm-1 and 1300 cm-1. These changes were linked with reactive oxygen species, hydroxyproline and triglyceride levels in ProliHHs, and the hypothesis were consistent with the corresponding assay results. Conclusions: In brief, Raman spectroscopy was successfully employed to identify different stages of ProliHHs during dedifferentiation process. The approach can simultaneously trace multiple changes of cellular components from somatic cells to progenitor cells.

scholarly journals Oral Cancer Discrimination and Novel Oral Epithelial Dysplasia Stratification Using FTIR Imaging and Machine Learning

Diagnostics ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 2133
Author(s):  
Rong Wang ◽  
Aparna Naidu ◽  
Yong Wang
Keyword(s):  
Machine Learning ◽  
Cluster Analysis ◽  
Discriminant Analysis ◽  
Oral Cancer ◽  
Epithelial Dysplasia ◽  
Support Vector ◽  
Epithelial Tissue ◽  
Ftir Imaging ◽  
Oral Epithelial Dysplasia ◽  
Oral Epithelial

The Fourier transform infrared (FTIR) imaging technique was used in a transmission model for the evaluation of twelve oral hyperkeratosis (HK), eleven oral epithelial dysplasia (OED), and eleven oral squamous cell carcinoma (OSCC) biopsy samples in the fingerprint region of 1800–950 cm−1. A series of 100 µm × 100 µm FTIR imaging areas were defined in each sample section in reference to the hematoxylin and eosin staining image of an adjacent section of the same sample. After outlier removal, signal preprocessing, and cluster analysis, a representative spectrum was generated for only the epithelial tissue in each area. Two representative spectra were selected from each sample to reflect intra-sample heterogeneity, which resulted in a total of 68 representative spectra from 34 samples for further analysis. Exploratory analyses using Principal component analysis and hierarchical cluster analysis showed good separation between the HK and OSCC spectra and overlaps of OED spectra with either HK or OSCC spectra. Three machine learning discriminant models based on partial least squares discriminant analysis (PLSDA), support vector machines discriminant analysis (SVMDA), and extreme gradient boosting discriminant analysis (XGBDA) were trained using 46 representative spectra from 12 HK and 11 OSCC samples. The PLSDA model achieved 100% sensitivity and 100% specificity, while both SVM and XGBDA models generated 95% sensitivity and 96% specificity, respectively. The PLSDA discriminant model was further used to classify the 11 OED samples into HK-grade (6), OSCC-grade (4), or borderline case (1) based on their FTIR spectral similarity to either HK or OSCC cases, providing a potential risk stratification strategy for the precancerous OED samples. The results of the current study support the application of the FTIR-machine learning technique in early oral cancer detection.

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