scholarly journals Sex estimation in cranial remains: A comparison of machine learning and discriminant analysis in Italian populations

2020 ◽  
Author(s):  
A Pozzi ◽  
C Raffone ◽  
MG Belcastro ◽  
TL Camilleri-Carter
Keyword(s):  
Machine Learning ◽  
Discriminant Analysis ◽  
Linear Discriminant Analysis ◽  
Foramen Magnum ◽  
Sex Estimation ◽  
Learning Models ◽  
Linear Discriminant ◽  
Machine Learning Methods ◽  
Cranial Measurements ◽  
Machine Learning Models

ABSTRACTObjectivesUsing cranial measurements in two Italian populations, we compare machine learning methods to the more traditional method of linear discriminant analysis in estimating sex. We use crania in sex estimation because it is useful especially when remains are fragmented or displaced, and the cranium may be the only remains found.Materials and MethodsUsing the machine learning methods of decision tree learning, support-vector machines, k-nearest neighbor algorithm, and ensemble methods we estimate the sex of two populations: Samples from Bologna and samples from the island of Sardinia. We used two datasets, one containing 17 cranial measurements, and one measuring the foramen magnum.Results and DiscussionOur results indicate that machine learning models produce similar results to linear discriminant analysis, but in some cases machine learning produces more consistent accuracy between the sexes. Our study shows that sex can be accurately predicted (> 80%) in Italian populations using the cranial measurements we gathered, except for the foramen magnum, which shows a level of accuracy of ∼70% accurate which is on par with previous geometric morphometrics studies using crania in sex estimation. We also find that our trained machine learning models produce population-specific results; we see that Italian crania are sexually dimorphic, but the features that are important to this dimorphism differ between the populations.

Utilizing Blockchain Technology in Social Media Bot Identification

2020 ◽  
Author(s):  
Shreya Reddy ◽  
Lisa Ewen ◽  
Pankti Patel ◽  
Prerak Patel ◽  
Ankit Kundal ◽  
...  
Keyword(s):  
Machine Learning ◽  
Social Media ◽  
Gold Standard ◽  
The Internet ◽  
Learning Models ◽  
Current Time ◽  
Machine Learning Methods ◽  
Blockchain Technology ◽  
Modern Age ◽  
Machine Learning Models

<p>As bots become more prevalent and smarter in the modern age of the internet, it becomes ever more important that they be identified and removed. Recent research has dictated that machine learning methods are accurate and the gold standard of bot identification on social media. Unfortunately, machine learning models do not come without their negative aspects such as lengthy training times, difficult feature selection, and overwhelming pre-processing tasks. To overcome these difficulties, we are proposing a blockchain framework for bot identification. At the current time, it is unknown how this method will perform, but it serves to prove the existence of an overwhelming gap of research under this area.<i></i></p>

scholarly journals Application of Machine Learning Methods in the Task of Identifying User Accounts in Two Social Networks

2019 ◽  
pp. 29-43
Author(s):  
Anastasiya A. Korepanova ◽  
◽  
Valerii D. Oliseenko ◽  
Maxim V. Abramov ◽  
Alexander L. Tulupyev ◽  
...  
Keyword(s):  
Machine Learning ◽  
Social Networks ◽  
Information System ◽  
New Combination ◽  
Practical Significance ◽  
User Profiles ◽  
Learning Models ◽  
Machine Learning Methods ◽  
The Social ◽  
Machine Learning Models

The article describes the approach to solving the problem of comparing user profiles of different social networks and identifying those that belong to one person. An appropriate method is proposed based on a comparison of the social environment and the values of account profile attributes in two different social networks. The results of applying various machine learning models to solving this problem are compared. The novelty of the approach lies in the proposed new combination of various methods and application to new social networks. The practical significance of the study is to automate the process of determining the ownership of profiles in various social networks to one user. These results can be applied in the task of constructing a meta-profile of a user of an information system for the subsequent construction of a profile of his vulnerabilities, as well as in other studies devoted to social networks.

scholarly journals Automated Retraining of Machine Learning Models

2019 ◽  
Vol 8 (12) ◽  
pp. 445-452
Keyword(s):  
Machine Learning ◽  
Input Data ◽  
Research Work ◽  
Learning Models ◽  
Machine Learning Methods ◽  
Machine Learning Model ◽  
Crucial Component ◽  
Conventional Machine ◽  
Over Time ◽  
Machine Learning Models

Data is the most crucial component of a successful ML system. Once a machine learning model is developed, it gets obsolete over time due to presence of new input data being generated every second. In order to keep our predictions accurate we need to find a way to keep our models up to date. Our research work involves finding a mechanism which can retrain the model with new data automatically. This research also involves exploring the possibilities of automating machine learning processes. We started this project by training and testing our model using conventional machine learning methods. The outcome was then compared with the outcome of those experiments conducted using the AutoML methods like TPOT. This helped us in finding an efficient technique to retrain our models. These techniques can be used in areas where people do not deal with the actual working of a ML model but only require the outputs of ML processes

scholarly journals A pitfall for machine learning methods aiming to predict across cell types

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Jacob Schreiber ◽  
Ritambhara Singh ◽  
Jeffrey Bilmes ◽  
William Stafford Noble
Keyword(s):  
Gene Expression ◽  
Machine Learning ◽  
Cell Types ◽  
Chromatin Domain ◽  
Learning Models ◽  
Machine Learning Methods ◽  
Domain Boundaries ◽  
Average Activity ◽  
Test Sets ◽  
Machine Learning Models

AbstractMachine learning models that predict genomic activity are most useful when they make accurate predictions across cell types. Here, we show that when the training and test sets contain the same genomic loci, the resulting model may falsely appear to perform well by effectively memorizing the average activity associated with each locus across the training cell types. We demonstrate this phenomenon in the context of predicting gene expression and chromatin domain boundaries, and we suggest methods to diagnose and avoid the pitfall. We anticipate that, as more data becomes available, future projects will increasingly risk suffering from this issue.

scholarly journals Benchmarking machine learning models for the analysis of genetic data using FRESA.CAD Binary Classification Benchmarking

2019 ◽  
Author(s):  
Javier de Velasco Oriol ◽  
Antonio Martinez-Torteya ◽  
Victor Trevino ◽  
Israel Alanis ◽  
Edgar E. Vallejo ◽  
...  
Keyword(s):  
Machine Learning ◽  
Model Selection ◽  
Binary Classification ◽  
Genetic Data ◽  
R Package ◽  
Learning Models ◽  
Classification Problems ◽  
Machine Learning Methods ◽  
Computational Perspective ◽  
Machine Learning Models

AbstractBackgroundMachine learning models have proven to be useful tools for the analysis of genetic data. However, with the availability of a wide variety of such methods, model selection has become increasingly difficult, both from the human and computational perspective.ResultsWe present the R package FRESA.CAD Binary Classification Benchmarking that performs systematic comparisons between a collection of representative machine learning methods for solving binary classification problems on genetic datasets.ConclusionsFRESA.CAD Binary Benchmarking demonstrates to be a useful tool over a variety of binary classification problems comprising the analysis of genetic data showing both quantitative and qualitative advantages over similar packages.

scholarly journals Single Cell Raman Spectroscopy to Identify Different Stages of Proliferating Human Hepatocytes for Cell Therapy

2021 ◽  
Author(s):  
Chen Ma ◽  
Ludi Zhang ◽  
Ting He ◽  
Huiying Cao ◽  
Chenhui Ma ◽  
...  
Keyword(s):  
Machine Learning ◽  
Raman Spectroscopy ◽  
Discriminant Analysis ◽  
Cell Therapy ◽  
Linear Discriminant Analysis ◽  
Learning Model ◽  
Human Hepatocytes ◽  
Linear Discriminant ◽  
Analytical Technique ◽  
Machine Learning Model

Abstract Background: Cell therapy provides hope for treatment of advanced liver failure. Proliferating human hepatocytes (ProliHHs) were derived from primary human hepatocytes (PHH) and as potential alternative for cell therapy in liver diseases. Due to the continuous decline of mature hepatic genes and increase of progenitor like genes during ProliHHs expanding, it is challenge to monitor the critical changes of the whole process. Raman microspectroscopy is a noninvasive, label free analytical technique with high sensitivity capacity. In this study, we evaluated the potential and feasibility to identify ProliHHs from PHH with Raman spectroscopy.Methods: Raman spectra were collected at least 600 single spectrum for PHH and ProliHHs at different stages (Passage 1 to Passage 4). Linear discriminant analysis and a two-layer machine learning model were used to analyze the Raman spectroscopy data. Significant differences in Raman bands were validated by the associated conventional kits.Results: Linear discriminant analysis successfully classified ProliHHs at different stages and PHH. A two-layer machine learning model was established and the overall accuracy was at 84.6%. Significant differences in Raman bands have been found within different ProliHHs cell groups, especially changes at 1003 cm-1, 1206 cm-1 and 1300 cm-1. These changes were linked with reactive oxygen species, hydroxyproline and triglyceride levels in ProliHHs, and the hypothesis were consistent with the corresponding assay results. Conclusions: In brief, Raman spectroscopy was successfully employed to identify different stages of ProliHHs during dedifferentiation process. The approach can simultaneously trace multiple changes of cellular components from somatic cells to progenitor cells.

scholarly journals Detection of Online Fake News Using Blending Ensemble Learning

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Arvin Hansrajh ◽  
Timothy T. Adeliyi ◽  
Jeanette Wing
Keyword(s):  
Machine Learning ◽  
Performance Metrics ◽  
Machine Learning Algorithms ◽  
Stochastic Gradient Descent ◽  
Support Vector ◽  
Fake News ◽  
Learning Models ◽  
Linear Discriminant ◽  
Proposed Model ◽  
Machine Learning Models

The exponential growth in fake news and its inherent threat to democracy, public trust, and justice has escalated the necessity for fake news detection and mitigation. Detecting fake news is a complex challenge as it is intentionally written to mislead and hoodwink. Humans are not good at identifying fake news. The detection of fake news by humans is reported to be at a rate of 54% and an additional 4% is reported in the literature as being speculative. The significance of fighting fake news is exemplified during the present pandemic. Consequently, social networks are ramping up the usage of detection tools and educating the public in recognising fake news. In the literature, it was observed that several machine learning algorithms have been applied to the detection of fake news with limited and mixed success. However, several advanced machine learning models are not being applied, although recent studies are demonstrating the efficacy of the ensemble machine learning approach; hence, the purpose of this study is to assist in the automated detection of fake news. An ensemble approach is adopted to help resolve the identified gap. This study proposed a blended machine learning ensemble model developed from logistic regression, support vector machine, linear discriminant analysis, stochastic gradient descent, and ridge regression, which is then used on a publicly available dataset to predict if a news report is true or not. The proposed model will be appraised with the popular classical machine learning models, while performance metrics such as AUC, ROC, recall, accuracy, precision, and f1-score will be used to measure the performance of the proposed model. Results presented showed that the proposed model outperformed other popular classical machine learning models.

Improved Interpretability of Machine Learning Model Using Unsupervised Clustering: Predicting Time to First Treatment in Chronic Lymphocytic Leukemia

2019 ◽  
pp. 1-11 ◽  
Author(s):  
David Chen ◽  
Gaurav Goyal ◽  
Ronald S. Go ◽  
Sameer A. Parikh ◽  
Che G. Ngufor
Keyword(s):  
Machine Learning ◽  
Risk Stratification ◽  
Unsupervised Clustering ◽  
Support Vector ◽  
Learning Models ◽  
Learning Methods ◽  
Machine Learning Methods ◽  
Continuous Output ◽  
Time To First Treatment ◽  
Machine Learning Models

PURPOSE Time to event is an important aspect of clinical decision making. This is particularly true when diseases have highly heterogeneous presentations and prognoses, as in chronic lymphocytic lymphoma (CLL). Although machine learning methods can readily learn complex nonlinear relationships, many methods are criticized as inadequate because of limited interpretability. We propose using unsupervised clustering of the continuous output of machine learning models to provide discrete risk stratification for predicting time to first treatment in a cohort of patients with CLL. PATIENTS AND METHODS A total of 737 treatment-naïve patients with CLL diagnosed at Mayo Clinic were included in this study. We compared predictive abilities for two survival models (Cox proportional hazards and random survival forest) and four classification methods (logistic regression, support vector machines, random forest, and gradient boosting machine). Probability of treatment was then stratified. RESULTS Machine learning methods did not yield significantly more accurate predictions of time to first treatment. However, automated risk stratification provided by clustering was able to better differentiate patients who were at risk for treatment within 1 year than models developed using standard survival analysis techniques. CONCLUSION Clustering the posterior probabilities of machine learning models provides a way to better interpret machine learning models.

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