The Burden of Traumatic Brain Injury in Sub-Saharan Africa: A Scoping Review

Introduction Studies from Sub-Saharan Africa (SSA) countries have reported on the incidence and case fatality rate of children with Traumatic Brain Injury (TBI). However, there is lack of a general epidemiologic description of the phenomenon in this sub-region underpinning the need for an accurate and reliable estimate of incidence and outcome of children (0–18 years) with TBI. This study therefore, extensively reviewed data to reliably estimate incidence, case fatality rate of children with TBI and its mechanism of injury in SSA. Methods Electronic databases were systematically searched in English via Medline (PubMed), Google Scholar, and Africa Journal Online (AJOL). Two independent authors performed an initial screening of studies based on the details found in their titles and abstracts. Studies were assessed for quality/risk of bias using the modified Newcastle-Ottawa Scale (NOS). The pooled case fatality rate and incidence were estimated using DerSimonian and Laird random-effects model (REM). A sub-group and sensitivity analyses were performed. Publication bias was checked by the funnel plot and Egger’s test. Furthermore, trim and fill analysis was used to adjust for publication bias using Duval and Tweedie’s method. Results Thirteen (13) hospital-based articles involving a total of 40685 participants met the inclusion criteria. The pooled case fatality rate for all the included studies in SSA was 8.0%; [95% CI: 3.0%-13.0%], and the approximate case fatality rate was adjusted to 8.2%, [95% CI:3.4%-13.0%], after the trim-and-fill analysis was used to correct for publication bias. A sub-group analysis of sub-region revealed that case fatality rate was 8% [95% CI: 2.0%-13.0%] in East Africa, 1.0% [95% CI: 0.1% -3.0%] in Southern Africa and 18.0% [95% CI: 6.0%-29.0%] in west Africa. The pooled incidence proportion of TBI was 18% [95% CI: 2.0%-33.0%]. The current review showed that Road Traffic Accident (RTA) was the predominant cause of children’s TBI in SSA. It ranged from 19.1% in South Africa to 79.1% in Togo. Conclusion TBI affects 18% of children aged 0 to 18 years, with almost one-tenth dying in SSA. The most common causes of TBI among this population in SSA were RTA and falls. TBI incidence and case fatality rate of people aged 0–18 years could be significantly reduced if novel policies focusing on reducing RTA and falls are introduced and implemented in SSA.

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Epidemiology, Management, and Functional Outcomes of Traumatic Brain Injury in Sub-Saharan Africa

World Neurosurgery ◽

10.1016/j.wneu.2017.09.084 ◽

2017 ◽

Vol 108 ◽

pp. 650-655 ◽

Cited By ~ 12

Author(s):

Jessica Eaton ◽

Asma Bilal Hanif ◽

Joanna Grudziak ◽

Anthony Charles

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Functional Outcomes ◽

Sub Saharan Africa ◽

Sub Saharan

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P88 Paroxysmal sympathetic storm and the role of beta-blockers in traumatic brain injury: a scoping review protocol

BJS Open ◽

10.1093/bjsopen/zrab032.087 ◽

2021 ◽

Vol 5 (Supplement_1) ◽

Author(s):

Stéphane Nguembu ◽

Marco Meloni ◽

Geneviève Endalle ◽

Hugues Dokponou ◽

Olaoluwa Ezekiel Dada ◽

...

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Length Of Stay ◽

Glasgow Coma Scale ◽

Scoping Review ◽

Beta Blockers ◽

Clinical Signs ◽

Sympathetic Hyperactivity ◽

Paroxysmal Sympathetic Hyperactivity

Abstract Introduction Most cases of paroxysmal sympathetic hyperactivity (PSH) result from traumatic brain injury (TBI). Little is known about its pathophysiology and treatment, and several neuroprotective drugs are used including beta-blockers. The aim of our study is to collate existing evidence of the role of beta-blockers in the treatment of PSH. Method We will search MEDLINE, Web of Science, EMBASE, Cochrane, and Google Scholar. The search terms used will cover the following terms: “paroxysmal sympathetic hyperactivity”, “traumatic brain injury” and “beta-blockers.”: No language or geographical restrictions will be applied. Two independent co-authors will screen the titles and abstracts of each article following predefined inclusion and exclusion criteria. If there is a conflict the two reviewers will find a consensus and if they cannot a third co-author will decide. Using a pre-designed and pre-piloted data extraction form, data from each included citation will be collected (authors identification, study type, TBI severity, type of beta-blockers used, dosage of the drug, clinical signs of PSH, Glasgow Coma Scale, Glasgow Outcome Scale, mortality, morbidity and length of stay). Simple descriptive data analyses will be performed and the results will be presented both in a narrative and tabular form. Results The effectiveness of beta-blockers in post-TBI PHS will be evaluated through clinical signs of PHS(increased heart rate, respiratory rate, temperature, blood pressure, and sweating), Glasgow Coma Scale, and Glasgow Outcome Scale. mortality, morbidity and length of stay. Conclusion At the end of this scoping review we will design a systematic review with metaanalysis if there are a reasonable number of studies otherwise we will design a randomized controlled trial.

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Representation in rehabilitation research of adults with traumatic brain injury and depression: A scoping review

Brain Injury ◽

10.1080/02699052.2021.1894481 ◽

2021 ◽

pp. 1-10

Author(s):

Adora Chui ◽

Samantha Seaton ◽

Bonnie Kirsh ◽

Deirdre R. Dawson ◽

Heather Colquhoun

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Scoping Review ◽

Rehabilitation Research

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Protocol for a scoping review to identify and map in-service education and training materials for midwifery care in sub-Saharan Africa from 2000 to 2020

BMJ Open ◽

10.1136/bmjopen-2020-047118 ◽

2021 ◽

Vol 11 (3) ◽

pp. e047118

Author(s):

Joanne Welsh ◽

Mechthild M Gross ◽

Claudia Hanson ◽

Hashim Hounkpatin ◽

Ann-Beth Moller

Keyword(s):

Scoping Review ◽

Maternal Mortality Ratio ◽

Newborn Care ◽

Education And Training ◽

Sub Saharan Africa ◽

Midwifery Care ◽

Training Materials ◽

Service Training ◽

Sub Saharan ◽

And Training

IntroductionMaternal and neonatal mortality are disproportionally high in low-and middle-income countries. In 2017 the global maternal mortality ratio was estimated to be 211 per 100 000 live births. An estimated 66% of these deaths occurred in sub-Saharan Africa. Training programmes that aim to prepare providers of midwifery care vary considerably across sub-Saharan Africa in terms of length, content and quality. To overcome the shortfalls of pre-service training and support the provision of quality care, in-service training packages for providers of midwifery care have been developed and implemented in many countries in sub-Saharan Africa. We aim to identify what in-service education and training materials have been used for providers of midwifery care between 2000 and 2020 and map their content to the International Confederation of Midwives’ Essential Competencies for Midwifery Practice (ICM Competencies), and the Lancet Midwifery Series Quality Maternal and Newborn Care (QMNC) framework.Methods and analysisA search will be conducted for the years 2000–2020 in Cumulative Index of Nursing and Allied Health Literature, PubMed/MEDLINE, Social Sciences Citation Index, African Index Medicus and Google Scholar. A manual search of reference lists from identified studies and a hand search of literature from international partner organisations will be performed. Information retrieved will include study context, providers trained, focus of training and design of training. Original content of identified education and training materials will be obtained and mapped to the ICM Competencies and the Lancet Series QMNC.Ethics and disseminationA scoping review is a secondary analysis of published literature and does not require ethical approval. This scoping review will give an overview of the education and training materials used for in-service training for providers of midwifery care in sub-Saharan Africa. Mapping the content of these education and training materials to the ICM Competencies and The Lancet Series QMNC will allow us to assess their appropriateness. Findings from the review will be reflected to stakeholders involved in the design and implementation of such materials. Additionally, findings will be published in a peer-reviewed journal, and used to inform the design and content of an in-service training package for providers of midwifery care as part of the Action Leveraging Evidence to Reduce perinatal morTality and morbidity (ALERT) study, (https://alert.ki.se/) a multi-country study in Benin, Malawi, Tanzania and Uganda.Trial registration numberPACTR202006793783148; Post-results.

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Mapping evidence on the distribution of the costs associated with cancer of prostate, cervix, and female breast in the sub-Saharan Africa: protocol for a scoping review

Systematic Reviews ◽

10.1186/s13643-021-01672-y ◽

2021 ◽

Vol 10 (1) ◽

Author(s):

Cebisile Ngcamphalala ◽

Ellinor Ostensson ◽

Mbuzeleni Hlongwa ◽

Themba G. Ginindza

Keyword(s):

Systematic Reviews ◽

Scoping Review ◽

Economic Burden ◽

Indirect Costs ◽

Economic Consequences ◽

Sub Saharan Africa ◽

Breast Cancers ◽

Direct And Indirect Costs ◽

Female Breast ◽

Sub Saharan

Abstract Background Despite the well-documented information on cancer prevention and management, among noncommunicable diseases (NCDs), globally, cancer continues to be the second leading cause of morbidity and mortality with devastating economic consequences. The burden is disproportionately more among developing countries and the extent of evidence available on the economic consequences (direct and indirect costs) of cancer remains unknown in low-income countries particularly in the sub-Saharan region. Understanding the costs of illness is important to inform decision-making on setting up health care policies and informing economic evaluation of interventions. This study aims to map evidence on the distribution of the economic burden (direct and indirect costs) associated with prevention, diagnosis, and treatment of three predominant cancers: prostate, cervix, and female breast in the sub-Saharan Africa. Methods This scoping review will be reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews (PRISMA-ScR), and will be conducted following Arksey and O’Malley’s framework. We will search PubMed/MEDLINE, Web of Science, CINHAL (via EBSCOhost platform), Science Direct, Cochrane Database of Systematic Reviews, Africa-Wide Information, Google Scholar, and WHO Library. We will perform hand-searching of the reference lists of included studies and other relevant documents. Two reviewers will independently screen all citations, full-text articles, and abstract data. We will include primary studies from all study designs reporting costs associated with prevention, diagnosis and treatment of prostate, cervical, and breast cancers in the sub-Saharan region. Data analysis will involve quantitative (e.g., frequencies) and qualitative (e.g., thematic analysis) methods. A narrative summary of findings will be presented. Discussion This review will map the extent of information available on the economic burden (direct and indirect costs) of prostate, cervical, and breast cancers in the sub-Saharan region. Further guidance for future research in the subject area will be discussed. Systematic review registration Open Science Framework

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Autism spectrum disorder in sub-saharan africa: A comprehensive scoping review

Autism Research ◽

10.1002/aur.1766 ◽

2017 ◽

Vol 10 (5) ◽

pp. 723-749 ◽

Cited By ~ 28

Author(s):

Lauren Franz ◽

Nola Chambers ◽

Megan von Isenburg ◽

Petrus J. de Vries

Keyword(s):

Autism Spectrum Disorder ◽

Scoping Review ◽

Autism Spectrum ◽

Spectrum Disorder ◽

Sub Saharan Africa ◽

Sub Saharan

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Barriers to the practice of exclusive breastfeeding among HIV-positive mothers in sub-Saharan Africa: A Scoping Review of counselling, socioeconomic and cultural factors

Journal of AIDS and HIV Research ◽

10.5897/jahr2015.0353 ◽

2016 ◽

Vol 8 (6) ◽

pp. 70-79 ◽

Cited By ~ 9

Author(s):

AL Mujtaba Maryam ◽

Sam Agudu Nadia ◽

Khatri Rosemary

Keyword(s):

Scoping Review ◽

Exclusive Breastfeeding ◽

Cultural Factors ◽

Sub Saharan Africa ◽

Hiv Positive ◽

Hiv Positive Mothers ◽

Sub Saharan

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Synthesizing evidence on nutrition challenges among people living with HIV/AIDS in sub- Saharan Africa: a protocol for a scoping review

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20192871 ◽

2019 ◽

Vol 6 (7) ◽

pp. 3173 ◽

Cited By ~ 1

Author(s):

Tafadzwa Dzinamarira ◽

Moreblessing Chipo Mashora

Keyword(s):

Health Outcomes ◽

Scoping Review ◽

Sub Saharan Africa ◽

Future Research ◽

People Living With Hiv ◽

Nutritional Management ◽

Sub Saharan ◽

Living With Hiv ◽

Improve Health ◽

Hiv Aids

Background: Good nutritional status is highly significant for individuals who are infected with HIV. However, they still face a number of nutritional challenges. The proposed scoping review will map literature on the nutritional challenges facing people living with HIV/AIDS (PLWH) and guide future research in nutritional management to improve health outcomes for PLWH. Here we outline a scoping review protocol designed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols (PRISMA-P 2015 Guidelines).Methods: The Arksey and O’Malley’s 2005 scoping methodological framework further improved by Levac et al. 2010 will guide the search and reporting. Searches will be conducted for eligible articles from MEDLINE (PubMed), MEDLINE, CINAHL, Academic Search Complete and ISI Web of Science (Science Citation Index) electronic databases. Two independent reviewers will conduct the search guided by an inclusion and exclusion criteria. Quality appraisal of the included articles will be conducted guided by the mixed methods appraisal tool 2018 version. We will employ NVivo version 12 for thematic content analysis.Conclusions: The findings of this review will guide future research in nutritional management to improve health outcomes for PLWH in sub-Saharan African. This review will be disseminated electronically in a published peer reviewed article and in print.

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Features of Rural Communities in Latin America and Sub-Saharan Africa That Influence Well-Being of Older Persons

Innovation in Aging ◽

10.1093/geroni/igab046.1622 ◽

2021 ◽

Vol 5 (Supplement_1) ◽

pp. 420-421

Author(s):

Andrew Banda ◽

Norah Keating ◽

Jaco Hoffman ◽

Jose Parodi ◽

Nereide Curreri

Keyword(s):

Older Adults ◽

Latin America ◽

Rural Communities ◽

Older People ◽

Scoping Review ◽

Older Persons ◽

Subjective Wellbeing ◽

Well Being ◽

Sub Saharan Africa ◽

Sub Saharan

Abstract In their recent volume, Critical Rural Gerontology, Skinner et al (2021) challenge us to set aside unidimensional notions of rural communities as bypassed vs very supportive; and to identify the elements of rurality that empower or exclude older people and how these differ across cultures and settings. Covid-19 has highlighted the need for safe and inclusive communities. Given that LMIC will be home to the majority of older adults (Gonzales et al. 2015), we undertook a scoping review of features of rural communities that influence wellbeing of older people in countries across Latin America and Sub-Saharan Africa. The review included literature in English, French, Spanish and Portuguese, using search engines MEDLINE, CINAHL Complete, PsycInfo, SocINDEX, SciELO, AJOL (Africa Journals Online), LILACS, Redalyc, LatinIndex and Clacso. Findings illustrate diversity in how community features including remoteness, infrastructure and belonging influence material, social and subjective wellbeing of older residents.

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