scholarly journals Associations between hair and salivary cortisol, salivary alpha-amylase, and temperament dimensions among 3–6-year-olds

2021 ◽  
Vol 135 ◽  
pp. 105042
Author(s):  
Katri Sääksjärvi ◽  
Elviira Lehto ◽  
Reetta Lehto ◽  
Eira Suhonen ◽  
Marja Leppänen ◽  
...  
Keyword(s):  
Salivary Cortisol ◽  
Alpha Amylase ◽  
Salivary Alpha Amylase

scholarly journals Study of Salivary Stress Factor Activity in Patients with Diabetes Mellitus During the Period of Adaptation to Complete Removable Laminar Dentures

2020 ◽  
Vol 27 (3) ◽  
pp. E202038
Author(s):  
Lyubov Leybyuk ◽  
Mykola Rozhko ◽  
Olena Rozhko
Keyword(s):  
Diabetes Mellitus ◽  
Salivary Cortisol ◽  
Acrylic Resin ◽  
Stress Factor ◽  
Alpha Amylase ◽  
Salivary Alpha Amylase ◽  
Group I ◽  
Patients With Diabetes ◽  
Cortisol Levels ◽  
Edentulous Patients

Diabetes mellitus is referred to as non-communicable epidemic of the 21st century and the fight against diabetes is one of medical and social challenges. One of its complications is damage to periodontal tissues that is accompanied by tooth loss. Any removable denture is a foreign body being a stress factor for the oral cavity. The objective of the research was to study dynamic changes in the activity of stress factor indicators, namely salivary cortisol, glucose and alpha-amylase levels in diabetic patients after prosthodontic treatment with complete removable laminar dentures. Materials and Methods. For this study, patients at the age of 45 to 74 years were divided into two groups: Group I included 52 edentulous patients with type 2 diabetes mellitus who were treated with acrylic resin complete removable laminar dentures; Group II comprised 52 edentulous patients without endocrine pathology who were treated with acrylic resin complete removable laminar dentures as well. Saliva served as the study material. The enzyme-linked immunosorbent assay was used to determine salivary cortisol levels. Glucose concentration in saliva was determined by a unified enzymatic method. Alpha-amylase activity was determined by the enzymatic colorimetric method. Results. According to the research results, before prosthodontic treatment, salivary cortisol levels of patients with diabetes mellitus were 2.4 times higher as compared to patients without somatic pathology. In phase I of adaptation to complete removable laminar dentures, in patients with diabetes mellitus, salivary cortisol concentration increased drastically by 1.4 times as compared to the indicator before prosthodontic treatment (5.61±0.83 ng/ml vs. 4.02±0.65 ng/ml, p<0.01), while in the group of patients without endocrine pathology, cortisol levels increased by 1.2 times; salivary glucose level of patients with diabetes mellitus increased by 1.3 times, while in patients without endocrine pathology, it increased by 1.1 times; in patients of Group I, salivary alpha-amylase levels increased by 1.2 times, while in patients of Group II, salivary alpha-amylase concentration increased by 1.05 times. Conclusions. In patients with diabetes mellitus, changes in saliva composition indicate a significant reduction in the adaptation mechanisms, that complicates and significantly prolongs the period of adaptation to complete removable laminar dentures.

scholarly journals Physiological responses to psychological stress: importance of adiposity in men aged 50–70 years

2014 ◽  
Vol 3 (3) ◽  
pp. 110-119 ◽  
Author(s):  
S U Jayasinghe ◽  
S J Torres ◽  
C A Nowson ◽  
A J Tilbrook ◽  
A I Turner
Keyword(s):  
Psychological Stress ◽  
Salivary Cortisol ◽  
Social Stress ◽  
Stress Test ◽  
Area Under The Curve ◽  
Peak Height ◽  
Trier Social Stress Test ◽  
Alpha Amylase ◽  
Percentage Body Fat ◽  
Salivary Alpha Amylase

We tested the hypothesis that overweight/obese men aged 50–70 years will have a greater salivary cortisol, salivary alpha amylase and heart rate (HR) responses to psychological stress compared with age matched lean men. Lean (BMI=20–25 kg/m2; n=19) and overweight/obese (BMI=27–35 kg/m2; n=17) men (50–70 years) were subjected to a well-characterised psychological stress (Trier Social Stress Test, TSST) at 1500 h. Concentrations of cortisol and alpha amylase were measured in saliva samples collected every 7–15 min from 1400 to 1700 h. HR was recorded using electrocardiogram. Body weight, BMI, percentage body fat, resting systolic and diastolic blood pressure and mean arterial pressure were significantly higher (P<0.05) in overweight/obese men compared with lean men. Both groups responded to the TSST with a substantial elevation in salivary cortisol (372%), salivary alpha amylase (123%) and HR (22%). These responses did not differ significantly between the groups (time×treatment interaction for salivary cortisol, salivary alpha amylase and HR; P=0.187, P=0.288, P=0.550, respectively). There were no significant differences between the groups for pretreatment values, peak height, difference between pretreatment values and peak height (reactivity) or area under the curve for salivary cortisol, salivary alpha amylase or HR (P>0.05 for all). The results showed that, for men with a moderate level of overweight/obesity who were otherwise healthy, the response of salivary cortisol, salivary alpha amylase and HR to acute psychological stress was not impaired.

scholarly journals Salivary Alpha Amylase Enzyme and Salivary Cortisol Level in Depression after Treatment with Fluoxetine

2021 ◽  
Vol 9 (T3) ◽  
pp. 144-149
Author(s):  
Andi Jayalangkara Tanra ◽  
Hawaidah Madeali ◽  
Mayamariska Sanusi ◽  
Saidah Syamsuddin ◽  
Sonny Teddy Lisal
Keyword(s):  
Salivary Cortisol ◽  
Depressive Disorders ◽  
Rating Scale ◽  
Antidepressant Drug ◽  
Alpha Amylase ◽  
Salivary Alpha Amylase ◽  
Potential Biomarker ◽  
Salivary Cortisol Level ◽  
Healthy Control ◽  
Cortisol Levels

BACKGROUND: Hypothalamic-pituitary-adrenal axis and its end product cortisol have been extensively investigated in patients with depressive disorders for many years. Recently, salivary alpha-amylase (sAA) had emerged as a new biomarker with non-invasive and more convenience protocol for measuring sympathetic activity which were also associated with depression. Selective Serotonin Reuptake Inhibitor is antidepressant drug extensively used to treat depression. AIM: The aim of this study was to determine whether decrease of sAA and salivary cortisol levels could be observed in subjects with depression who were treated by fluoxetine. METHODS: The total subjects were 25 depressed subjects and ten healthy controls. sAA was examined before therapy, and after 2, 4, and 6 weeks of fluoxetine administration using a portable cocorometer. Salivary cortisol was examined before therapy, after 4 and 6 weeks of fluoxetine administration with Elisa method. The therapeutic effect was assessed with Hamilton Depression Rating Scale (HDRS). RESULTS: sAA and cortisol levels were significantly decreased after fluoxetine administration (p < 0.001), followed by at least 50% reduction of HDRS scores after 6 weeks of fluoxetine administration. Levels of sAA and cortisol were higher in the depression group than in the healthy control. CONCLUSIONS: Measurement of sAA levels can be used as a potential biomarker of therapeutic response in depressed patients in addition to salivary cortisol.

scholarly journals Measurements of Salivary Alpha Amylase and Salivary Cortisol in Hominoid Primates Reveal Within-Species Consistency and Between-Species Differences

PLoS ONE ◽  
2013 ◽  
Vol 8 (4) ◽  
pp. e60773 ◽  
Author(s):  
Verena Behringer ◽  
Claudia Borchers ◽  
Tobias Deschner ◽  
Erich Möstl ◽  
Dieter Selzer ◽  
...  
Keyword(s):  
Salivary Cortisol ◽  
Species Differences ◽  
Alpha Amylase ◽  
Salivary Alpha Amylase

scholarly journals Salivary Cortisol, Salivary Alpha Amylase, and the Dental Anxiety Scale

2013 ◽  
Vol 60 (2) ◽  
pp. 46-53 ◽  
Author(s):  
Hana Sadi ◽  
Matthew Finkelman ◽  
Morton Rosenberg
Keyword(s):  
Salivary Cortisol ◽  
Dental Anxiety ◽  
Saliva Sample ◽  
Anxiety Scale ◽  
Alpha Amylase ◽  
Cross Sectional ◽  
Convenience Sample ◽  
Salivary Alpha Amylase ◽  
History Of ◽  
Cross Sectional Design

AbstractThe aim of this study was to investigate the correlation between dental anxiety, salivary cortisol, and salivary alpha amylase (sAA) levels. Furthermore, the aim was to look into individual differences such as age, race, gender, any existing pain, or traumatic dental experience and their effect on dental anxiety. This study followed a cross-sectional design and included a convenience sample of 46. Every patient was asked to complete the Dental Anxiety Scale (DAS) and a basic demographic/dental history questionnaire. A saliva sample, utilizing the method of passive drooling, was then collected in 2-mL cryovials. Samples were analyzed for salivary cortisol and sAA levels by Salimetrics. Significant associations were observed between DAS scores and presence of pain and history of traumatic dental experience. However, no significant correlations were observed between DAS, cortisol, and sAA levels. Our study reconfirms that dental anxiety is associated with presence of pain and a history of traumatic dental experience. On the other hand, our study was the first to our knowledge to test the correlation between the DAS and sAA; nevertheless, our results failed to show any significant correlation between dental anxiety, cortisol, and sAA levels.

scholarly journals Salivary Alpha-amylase Enzyme and Salivary Cortisol Level in Depression after Treatment with Fluoxetine

2021 ◽  
Vol 9 (T3) ◽  
pp. 305-310
Author(s):  
Andi Jayalangkara Tanra ◽  
Hawaidah Madeali ◽  
Mayamariska Sanusi ◽  
Saidah Syamsuddin ◽  
Sonny Teddy Lisal
Keyword(s):  
Cortisol Level ◽  
Salivary Cortisol ◽  
Depressive Disorders ◽  
Rating Scale ◽  
Antidepressant Drug ◽  
Alpha Amylase ◽  
Salivary Alpha Amylase ◽  
Potential Biomarker ◽  
Salivary Cortisol Level ◽  
Healthy Control

Hypothalamic-Pituitary-Adrenal (HPA) axis and its end product cortisol have been extensively investigated in patients with depressive disorders for many years. Recently, salivary alpha-amylase (sAA) had emerged as a new biomarker with non-invasive and more convenience protocol for measuring sympathetic activity which were also associated with depression. Selective Serotonin Reuptake Inhibitor (SSRI) is antidepressant drug extensively used to treat depression. The aim of this study was to determine whether decrease of sAA and salivary cortisol levels could be observed in subjects with depression who were treated by fluoxetine. The total subjects were 25 depressed subjects and 10 healthy controls. sAA was examined before therapy, and after 2, 4 and 6 weeks of fluoxetine administration using a portable cocorometer. Salivary cortisol was examined before therapy, after 4 and 6 weeks of fluoxetine administration with Elisa method. The therapeutic effect was assessed with Hamilton Depression Rating Scale (HDRS). Results: sAA and cortisol level were significantly decreased after fluoxetine administration (p<0.001) followed by at least 50% reduction of HDRS scores after 6 weeks of fluoxetine administration. Levels of sAA and cortisol were higher in the depression group than in the healthy control. Conclusions: Measurement of sAA levels can be used as a potential biomarker of therapeutic response in depressed patients in addition to salivary cortisol.

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