Relation between butyrylcholinesterase K variant, paraoxonase 1 (PON1) Q and R and apolipoprotein E ϵ4 genes in early-onset coronary artery disease

2002 ◽  
Vol 35 (3) ◽  
pp. 205-209 ◽  
Author(s):  
Bassam A Nassar ◽  
Sultan Darvesh ◽  
Lisa D Bevin ◽  
Kenneth Rockwood ◽  
Susan A Kirkland ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Apolipoprotein E ◽  
Early Onset ◽  
Paraoxonase 1 ◽  
Artery Disease ◽  
K Variant

Atheromatosis Extent in Coronary Artery Disease is not Correlated with Apolipoprotein-E Polymorphism and its Plasma Levels, but Associated with Cognitive Decline

2010 ◽  
Vol 999 (999) ◽  
pp. 1-8 ◽  
Author(s):  
Luciana Moreira Lima ◽  
Maria das Gracas Carvalho ◽  
Claudia Natalia Ferreira ◽  
Ana Paula Fernandes ◽  
Cirilo Pereira da Fonseca Neto ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Cognitive Decline ◽  
Apolipoprotein E ◽  
Plasma Levels ◽  
Apolipoprotein E Polymorphism ◽  
Artery Disease

PP-209: PARAOXONASE 1 ENZYME ACTIVITY IN METABOLIC SYNDROME PATIENTS WITHOUT CORONARY ARTERY DISEASE

2011 ◽  
Vol 147 ◽  
pp. S148
Author(s):  
E. Yucel ◽  
A. Aydinlar ◽  
A. Aydin Kaderli ◽  
T. Senturk ◽  
S. Gunay ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Metabolic Syndrome ◽  
Enzyme Activity ◽  
Coronary Artery ◽  
Paraoxonase 1 ◽  
Artery Disease

scholarly journals Relationship between rs854560PON1Gene Polymorphism and Tobacco Smoking with Coronary Artery Disease

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Joanna Iwanicka ◽  
Tomasz Iwanicki ◽  
Paweł Niemiec ◽  
Tomasz Nowak ◽  
Jolanta Krauze ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Cigarette Smoking ◽  
Relative Increase ◽  
Paraoxonase 1 ◽  
High Density Lipoproteins ◽  
Polish Population ◽  
Premature Cad ◽  
Traditional Risk Factors ◽  
Artery Disease

Paraoxonase-1 (PON1) is the antioxidant marker of high-density lipoproteins protecting against atherosclerosis and coronary artery disease (CAD) phenotype. The purpose of the present study was to determine whether thePON1gene rs854560 polymorphism (163T>A) is associated with CAD in Polish population. rs854560 was genotyped in 494 subjects: 248 patients with premature CAD and 246 blood donors as a control. We found that the risk of CAD was significantly higher in TT homozygotes than in A allele carriers (OR = 1.87,p=0.041). The synergistic effect between the TT genotype and cigarette smoking was observed (SIM = 9.81; SI = 14.70). The relative increase in risk from interaction between factors was over 37 (RERI = 36.13). ThePON1polymorphism did not modulate the risk of CAD in response to exposure to other traditional risk factors. In conclusion, the rs854560 polymorphism may modulate the risk of CAD in response to cigarette smoking in Polish population. Carriers of TT genotype seem to be particularly at risk of CAD, when exposed to cigarette smoking.

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