Clinical profile of comorbid major depression and alcohol use disorders in an initial psychiatric evaluation

1995 ◽  
Vol 36 (4) ◽  
pp. 260-266 ◽  
Author(s):  
Ihsan M Salloum ◽  
Juan E Mezzich ◽  
Jack Cornelius ◽  
Nancy L Day ◽  
Dennis Daley ◽  
...  
Keyword(s):  
Major Depression ◽  
Alcohol Use ◽  
Alcohol Use Disorders ◽  
Clinical Profile ◽  
Psychiatric Evaluation

scholarly journals High Frequency and Intensity of Drinking may Attenuate Increased Inflammatory Cytokine Levels of Major Depression in Alcohol-use Disorders

2014 ◽  
Vol 20 (10) ◽  
pp. 898-904 ◽  
Author(s):  
Sudan P. Neupane ◽  
Lars Lien ◽  
Priscilla Martinez ◽  
Pål Aukrust ◽  
Thor Ueland ◽  
...  
Keyword(s):  
Major Depression ◽  
Alcohol Use ◽  
High Frequency ◽  
Inflammatory Cytokine ◽  
Alcohol Use Disorders ◽  
Cytokine Levels

scholarly journals Lifetime experience of multiple common mental disorders and 19-year mortality: results from a Canadian population-based cohort

2019 ◽  
Vol 29 ◽  
Author(s):  
M. Kingsbury ◽  
E. Sucha ◽  
N. J. Horton ◽  
H. Sampasa-Kanyinga ◽  
J. M. Murphy ◽  
...  
Keyword(s):  
Major Depression ◽  
Alcohol Use ◽  
Mental Disorders ◽  
Panic Disorder ◽  
Psychiatric Disorders ◽  
Alcohol Use Disorders ◽  
Risk Of Death ◽  
Risk Of Mortality ◽  
Increased Risk ◽  
The Impact

Abstract Aims To examine the impact of multiple psychiatric disorders over the lifetime on risk of mortality in the general population. Methods Data came from a random community-based sample of 1397 adults in Atlantic Canada, recruited in 1992. Major depression, dysthymia, panic disorder, generalised anxiety disorder and alcohol use disorders were assessed using the Diagnostic Interview Schedule (DIS). Vital status of participants through 2011 was determined using probabilistic linkages to the Canadian Mortality Database. Cox proportional hazard models with age at study entry as the time scale were used to investigate the relationship between DIS diagnoses and mortality, adjusted for participant education, smoking and obesity at baseline. Results Results suggested that mood and anxiety disorders rarely presented in isolation – the majority of participants experienced multiple psychiatric disorders over the lifetime. Elevated risk of death was found among men with both major depression and dysthymia (HR 2.56; 95% CI 1.12–5.89), depression and alcohol use disorders (HR 2.45; 95% CI 1.18–5.10) and among men and women who experienced both panic disorder and alcohol use disorders (HR 3.80; 95% CI 1.19–12.16). Conclusion The experience of multiple mental disorders over the lifetime is extremely common, and associated with increased risk of mortality, most notably among men. Clinicians should be aware of the importance of considering contemporaneous symptoms of multiple psychiatric conditions.

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