Plasma Methylated Reprimo as a Non-Invasive Biomarker for Precancerous Gastric Lesions: A Cross Sectional Study in an Amerindian/Hispanic Population from an Endemic Region of Chile

2017 ◽  
Vol 152 (5) ◽  
pp. S1025
Author(s):  
James Leathers ◽  
Robinson G. Gonzalez ◽  
María J. Maturana ◽  
Juan C. Araya ◽  
Raúl Araya ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Hispanic Population ◽  
Gastric Lesions ◽  
Sectional Study ◽  
Endemic Region ◽  
Cross Sectional ◽  
Non Invasive ◽  
Precancerous Gastric Lesions

scholarly journals Serotype Distribution of Streptococcus pneumoniae Carriage ‎in Six-Month-Old Infants: A Cross-sectional Study During 2017-18, Tehran, ‎Iran

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Shirin Sayyahfar ◽  
Abdoulreza Esteghamati ◽  
Seyed Alireza Fahimzad ◽  
Safura Hajisadeghi Isfahani ◽  
Ali Nazari Alam ◽  
...  
Keyword(s):  
Streptococcus Pneumoniae ◽  
Multiplex Pcr ◽  
Positive Culture ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Serotype Distribution ◽  
Cross Sectional ◽  
Non Invasive ◽  
Healthy Infants ◽  
Invasive Infections

Background: Streptococcus pneumoniae is recognized as one of the main pathogens inducing several invasive and non-invasive infections in children. Objective: The present study aimed to evaluate the serotype distribution of S. pneumoniae in six–month–old carriers. Methods: This study encompassed 600 six-month-old healthy infants whose pharyngeal swap samples were collected and then cultured to isolate S. pneumoniae. Twenty- five different serotypes were defined on positive culture samples by multiplex PCR. Results: In this study, 13 cases (2.2%) were positive S. pneumonia. The most common isolated serotypes of S. pneumoniae were serotypes 23F (n = 6, 1%) and 3 (n = 3, 0.5%), respectively. Notably, the most frequent serotype in formula-fed infants (n = 300) was Serotype 23F (n = 5, 1.7%); however, Serotype 3 (n = 3, 1%) was the most frequent one in breastfed participants (n = 300). According to the findings, the overall coverage of PCV10, PCV13, and PPSV23 on the S. pneumoniae serotypes at the age of six months was 50%, 73%, and 85%, respectively. Conclusions: At this age, the type of feeding could not significantly affect the frequency rate of S. pneumoniae colonization, while the serotype distributions in the two breastfed and formula-fed groups were different.

scholarly journals Exhaled volatile substances in children suffering from type 1 diabetes mellitus: results from a cross-sectional study

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Phillip Trefz ◽  
Juliane Obermeier ◽  
Ruth Lehbrink ◽  
Jochen K. Schubert ◽  
Wolfram Miekisch ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Metabolic Control ◽  
Cross Sectional Study ◽  
Healthy Controls ◽  
Sectional Study ◽  
Cross Sectional ◽  
Non Invasive

Abstract Monitoring metabolic adaptation to type 1 diabetes mellitus in children is challenging. Analysis of volatile organic compounds (VOCs) in exhaled breath is non-invasive and appears as a promising tool. However, data on breath VOC profiles in pediatric patients are limited. We conducted a cross-sectional study and applied quantitative analysis of exhaled VOCs in children suffering from type 1 diabetes mellitus (T1DM) (n = 53) and healthy controls (n = 60). Both groups were matched for sex and age. For breath gas analysis, a very sensitive direct mass spectrometric technique (PTR-TOF) was applied. The duration of disease, the mode of insulin application (continuous subcutaneous insulin infusion vs. multiple daily insulin injection) and long-term metabolic control were considered as classifiers in patients. The concentration of exhaled VOCs differed between T1DM patients and healthy children. In particular, T1DM patients exhaled significantly higher amounts of ethanol, isopropanol, dimethylsulfid, isoprene and pentanal compared to healthy controls (171, 1223, 19.6, 112 and 13.5 ppbV vs. 82.4, 784, 11.3, 49.6, and 5.30 ppbV). The most remarkable differences in concentrations were found in patients with poor metabolic control, i.e. those with a mean HbA1c above 8%. In conclusion, non-invasive breath testing may support the discovery of basic metabolic mechanisms and adaptation early in the progress of T1DM.

scholarly journals CORRELATION BETWEEN FRAILTY AND NON-INVASIVE CORONARY FLOW RESERVE: A CROSS SECTIONAL STUDY

2017 ◽  
Vol 69 (11) ◽  
pp. 2541
Author(s):  
Amjad M. Ahmed ◽  
Ihab Sulaiman ◽  
Mousa Alfaris ◽  
Dalia Ahmed ◽  
Ahmed Aljizeeri ◽  
...  
Keyword(s):  
Coronary Flow Reserve ◽  
Coronary Flow ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Non Invasive ◽  
Flow Reserve

scholarly journals Cross-Sectional Study to Assess Risk Factors for Leishmaniasis in an Endemic Region in Sri Lanka

2013 ◽  
Vol 89 (4) ◽  
pp. 742-749 ◽  
Author(s):  
Shalindra Ranasinghe ◽  
Hasini Wackwella ◽  
Rajitha Wickremasinghe ◽  
Samantha Bandara ◽  
Sundaramoorthy Sivanantharajah ◽  
...  
Keyword(s):  
Risk Factors ◽  
Sri Lanka ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Endemic Region ◽  
Cross Sectional

scholarly journals Neck circumference as an indicator of elevated central adiposity in children

2019 ◽  
Vol 22 (10) ◽  
pp. 1755-1761 ◽  
Author(s):  
Evelyn Valencia-Sosa ◽  
Clío Chávez-Palencia ◽  
Enrique Romero-Velarde ◽  
Alfredo Larrosa-Haro ◽  
Edgar Manuel Vásquez-Garibay ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Neck Circumference ◽  
Strong Positive Correlation ◽  
Central Adiposity ◽  
Sectional Study ◽  
Cross Sectional ◽  
Convenience Sample ◽  
Western Mexico ◽  
Non Invasive ◽  
Rural Settings

AbstractObjectiveWe aimed to study the correlation between neck circumference (NC) and anthropometric adiposity indicators, and to determine cut-off points of NC for both sexes to identify elevated central adiposity in schoolchildren in western Mexico.DesignCross-sectional study.SettingRural settings in western México.ParticipantsChildren from a convenience sample of six schools in Acatlán, Jalisco, Mexico (n 1802).ResultsNC showed a strong positive correlation with all anthropometric adiposity indicators in both sexes, which were notably higher in boys regardless of age. Noteworthy, waist circumference displayed the highest significant correlation when analysed by both age and sex. As age increased, NC cut-off points to identify elevated central adiposity ranged from 25·7 to 30·1 cm for girls and from 27·5 to 31·7 cm for boys.ConclusionsNC could be used as a simple, inexpensive and non-invasive indicator for central obesity assessment in Mexican schoolchildren.

scholarly journals Internal Lipid Profile and Body Lipid Profile in Relation to Cognition: A Cross-Sectional Study in Southern China

2020 ◽  
Vol 35 ◽  
pp. 153331752096266
Author(s):  
Lian Liu ◽  
Xiao Huang ◽  
Liang Feng ◽  
Yanqing Wu
Keyword(s):  
Cognitive Impairment ◽  
Lipid Profile ◽  
Southern China ◽  
Apoe Genotype ◽  
Cross Sectional Study ◽  
Lipid Profiles ◽  
Sectional Study ◽  
Body Lipid ◽  
Cross Sectional ◽  
Non Invasive

Aim: There are currently no established, clinically relevant, non-invasive markers of cognitive impairment, except for age and APOE genotype. Methods: A cross-sectional study of 1,296 participants from Nanchang, China, has been conducted. We collected data from Mini–Mental State Examination (MMSE) scores, internal lipid profiles and body lipid profiles, age and other factors that may have an effect on cognitive impairment. Results: Internal lipid profiles (OR = 1.03 [95%CI, 1.00-1.06], P = 0.024), body lipid profiles (OR = 1.05 [95%CI, 1.01-1.09], P = 0.014), and age (OR = 1.03 [95%CI, 1.01-1.05], P < 0.001) were all positively correlated with cognitive impairment. Conclusions: Cognitive impairment was more frequent in female patients with high internal lipid profiles or body lipid profiles, and these characteristics were related to age and education.

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