Epithelioid Sarcoma in the Hand

HAND ◽  
1983 ◽  
Vol os-15 (2) ◽  
pp. 228-230 ◽  
Author(s):  
Sorna Rajan ◽  
Tommy Skau
Keyword(s):  
Differential Diagnosis ◽  
Soft Tissue ◽  
Inflammatory Process ◽  
Benign Lesion ◽  
Initial Period ◽  
Epithelioid Sarcoma ◽  
Malignant Lesion ◽  
Malignant Tumour ◽  
Illustrative Case ◽  
The Third

An illustrative case of epithelioid sarcoma in the hand of a young man, causing considerable diagnostic problems, is presented. Epithelioid sarcoma is a malignant lesion, first described by Enzinger in 1970. Although epithelioid sarcoma is the third commonest soft tissue sarcoma in the upper extremity (Bryan, 1974) it still causes confusion in differential diagnosis, both to the surgeon and to the pathologist. Because of its deceptively harmless appearance during the initial period and its clinical and microscopical similarity to an inflammatory process, it is often mistaken for a benign lesion. The purpose of our paper is to draw attention to this rare malignant tumour. This case illustrates a course similar to those described previously. (Enzinger, 1970: Santiago, 1972).

Leiomyoma on the shaft of penis

Open Medicine ◽  
2010 ◽  
Vol 5 (5) ◽  
pp. 538-540
Author(s):  
R Siddharth ◽  
SN Mehra
Keyword(s):  
Differential Diagnosis ◽  
Soft Tissue ◽  
English Literature ◽  
Malignant Lesion ◽  
Surgical Excision ◽  
Effective Therapy ◽  
Histological Diagnosis ◽  
Pathologic Finding ◽  
Soft Tissue Tumours ◽  
Penile Neoplasm

AbstractPrimary soft tissue tumours of the penis, such as leiomyomas, are very rare. Most present as small and painless but gradually increasing swellings on the penis. To the best of our knowledge, only 9 cases have been reported in the literature so far. This rare pathologic finding, which usually mimics a malignant lesion, should be included in the differential diagnosis of penile neoplasm. Surgical excision of the lesion provides both the histological diagnosis and an effective therapy. We report a case of a large leiomyoma on the shaft of the penis measuring 8x5 cm, which possibly represents the largest reported leiomyoma of the penis in English literature till date.

scholarly journals A review of paediatric soft tissues masses referred to a tertiary musculoskeletal sarcoma centre

2021 ◽  
Vol 94 (1117) ◽  
pp. 20200790
Author(s):  
Catriona Reid ◽  
Asif Saifuddin
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Soft Tissues ◽  
Malignant Lesion ◽  
Malignant Tumour ◽  
Benign Tumour ◽  
Neoplastic Lesion ◽  
Soft Tissue Masses ◽  
Oncology Unit ◽  
Musculoskeletal Oncology

Objectives: To determine the differential diagnosis of musculoskeletal soft tissue masses in children referred to a specialist musculoskeletal oncology unit. Methods: All children (0–18 y) referred to a specialist musculoskeletal oncology unit over a 20-month period (September 2018–May 2020) were retrospectively reviewed. Demographic data and referral diagnoses were obtained from the electronic patient notes. MRI findings and histopathological results were recorded. The comparison of non-neoplastic, benign neoplastic and malignant diagnoses at the point of referral and final diagnosis was determined. Results: 116 patients were included, 60 (51.7%) males and 56 (48.3%) females with mean age of 10.6 years (3 months–18 years). 69 (59.5%) patients were referred with a suspected sarcoma, 29 (25.0%) with a suspected benign tumour and 18 (15.5%) with a non-neoplastic lesion. A diagnosis was achieved by histological assessment in 61 (52.6%) cases, microbiological assessment in 3 (2.6%) or clinical and imaging assessment in 52 (44.8%). 67 (57.8%) cases had non-neoplastic pathology, 39 (33.6%) a benign tumour, 4 (3.4%) an intermediate-grade tumour, 6 (5.2%) a malignant tumour. Conclusions: Although over half of children referred to a specialist musculoskeletal oncology unit were suspected of having a soft tissue sarcoma at referral, only 5.2% were diagnosed with a malignant tumour. Advances in knowledge: Approximately, 6 of 69 (8.7%) children referred to a specialist musculoskeletal oncology unit with a suspected soft tissue sarcoma will have a malignant lesion. Most paediatric soft tissue masses are non-neoplastic, the commonest diagnosis being a vascular malformation.

Epithelioid sarcoma of the neck: case report

2009 ◽  
Vol 123 (S31) ◽  
pp. 113-116 ◽  
Author(s):  
Y Ueda ◽  
H Chijiwa ◽  
T Nakashima
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Local Recurrence ◽  
Neck Dissection ◽  
Distant Metastasis ◽  
Epithelioid Sarcoma ◽  
Malignant Tumour ◽  
Final Diagnosis ◽  
History Of ◽  
Growing Mass

AbstractEpithelioid sarcoma is an aggressive, malignant tumour of the soft tissue which tends to arise in proximity to large tendons and aponeuroses. We report the case of a patient presenting with an epithelioid sarcoma arising in the neck. A 56-year-old man was referred with a three-year history of a sensory disorder as well as a slowly growing mass in his right neck. The patient underwent resection of the tumour by means of a conservative neck dissection. The final diagnosis, based on the histological and immunohistochemical findings, was epithelioid sarcoma. Radiotherapy was performed after the operation. The post-operative course was uneventful, and there was no local recurrence or distant metastasis.

Lesions of the Distal Phalanx: Imaging Overview

2019 ◽  
Vol 1 ◽  
pp. 47-56
Author(s):  
Ramanan Rajakulasingam ◽  
Christine Azzopardi ◽  
Jennifer Murphy ◽  
Mark Davies ◽  
Andoni Toms ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Wide Spectrum ◽  
Benign Lesion ◽  
Malignant Lesion ◽  
Soft Tissue Tumors ◽  
Distal Phalanx ◽  
Secondary Tumors ◽  
Lytic Lesions ◽  
Tumors Of The Hand ◽  
Radiological Changes

Lesions of the distal phalanx often pose a radiological dilemma as the differential diagnosis is potentially broad. Particularly for lytic lesions, there is a concern whether an underlying primary tumor or a metastatic deposit is present. Bone tumors of the hand are infrequent when compared to soft tissue tumors, and those involving the distal phalanx are very rare. Lesions of the distal phalanx may arise secondary to benign or malignant pathologies and may reflect primary or secondary tumors. The most common benign lesion is an enchondroma while the most frequent primary malignant lesion is chondrosarcoma. Inflammatory, metabolic, autoimmune, and traumatic pathologies may also present with a wide spectrum of radiological changes involving the distal phalanx. It is these tumor-like mimics which can further complicate diagnosis. We hope to highlight distinguishing features between these entities, allowing the radiologist to generate a clinically useful differential diagnosis. Even though most lesions are benign, it is crucial to differentiate them as some may be the first presentation of more a systemic condition.

scholarly journals Giant pelvic-perineal leiomyoma simulating a malignant lesion

2021 ◽  
Vol 4 (4) ◽  
pp. 01-04
Author(s):  
Papa Abdoulaye Bâ ◽  
Doudou Gueye ◽  
Thomas Marcel Mbar Wade ◽  
Jacques Noel Tendeng ◽  
Mohamed Lamine Diao ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Connective Tissue ◽  
Benign Lesion ◽  
Malignant Lesion ◽  
Soft Tissue Tumors ◽  
Surgical Approaches ◽  
Cytological Examination ◽  
Post Operative Period ◽  
Malignant Lesions

Introduction: Soft tissue tumors are benign or malignant lesions developing from connective tissue and its varieties. Case Report: A 35-year-old patient referred to us for management of a voluminous pelvic-perineal mass. The clinical and para clinical data were in favor of a malignant lesion. The treatment consisted of a wide excision of the tumor. The post-operative period was complicated by an anal incontinence needing a protective left iliac colostomy. A perinioraphy, sphincter refection, and re–establishment of the digestive continuity were performed later on. The cytological examination of the excised mass revealed a conclusive involute hyanilised leiomyoma. Conclusion: This contrast between the clinical, para clinical and histologic data in our patient confirm the diagnostic challenges of soft tissue tumors, hence the need for special technic to assure diagnostic certitude to avoid mutilating surgical approaches for a benign lesion.

scholarly journals Clinical analysis on the differential diagnosis of gastrointestinal neoplasms by real-time endoscopic ultrasonography

2020 ◽  
Vol 3 (3) ◽  
Author(s):  
Yumin Zhang
Keyword(s):  
Differential Diagnosis ◽  
Diagnostic Accuracy ◽  
Real Time ◽  
Endoscopic Ultrasonography ◽  
Elastic Strain ◽  
Digestive System ◽  
Benign Lesion ◽  
Malignant Lesion ◽  
Lesion Group ◽  
Tissue Elastography

Abstract: objective: to study and analyze the effect of real-time endoscopic ultrasonography in the differential diagnosis of gastrointestinal tumors.Selection methods: between January 2014 and January 2015 xinyang 53 cases of digestive system cancer patients admitted in hospital, a total of 79 substantial tumor of the digestive system lesions, all patients were diagnosed by endoscopic ultrasonography real-time tissue elastography, use elastic imaging score, for patients with lesions and their surrounding structures control the elastic strain rate ratio of measure and comparison analysis.Results: compared with the malignant lesion group, the difference between the benign lesion group and the benign lesion group was statistically significant (P<0.05).The ratio of elastic strain rate in benign lesion group was lower than that in malignant lesion group (P<0.05).The diagnostic accuracy, sensitivity and specificity were 91.14%, 94.74% and 81.82% respectively.Conclusion: endoscopic ultrasound real-time tissue elastography is effective in the differential diagnosis of digestive system tumors, and can effectively determine the benign and malignant tumors and improve the diagnostic accuracy.

Imaging Features of Primary Tumors of the Hand

2020 ◽  
Vol 16 ◽  
Author(s):  
Filippo Boriani ◽  
Edoardo Raposio ◽  
Costantino Errani
Keyword(s):  
Soft Tissue ◽  
Soft Tissues ◽  
Epithelioid Sarcoma ◽  
Case Series ◽  
Malignant Neoplasm ◽  
Benign Tumors ◽  
Imaging Features ◽  
Primary Tumors ◽  
Therapeutic Decisions ◽  
Tumors Of The Hand

: Musculoskeletal tumors of the hand are a rare entity and are divided into skeletal and soft tissue tumors. Either category comprises benign and malignant or even intermediate tumors. Basic radiology allows an optimal resolution of bone and related soft tissue areas, ultrasound and more sophisticated radiologic tools such as scintigraphy, CT and MRI allow a more accurate evaluation of tumor extent. Enchondroma is the most common benign tumor affecting bone, whereas chondrosarcoma is the most commonly represented malignant neoplasm localized to hand bones. In the soft tissues ganglions are the most common benign tumors and epithelioid sarcoma is the most frequently represented malignant tumor targeting hand soft tissues. The knowledge regarding diagnostic and therapeutic management of these tumors is often deriving from small case series, retrospective studies or even case reports. Evidences from prospective studies or controlled trials are limited and for this lack of clear and supported evidences data from the medical literature on the topic are controversial, in terms of demographics, clinical presentation, diagnosis prognosis and therapy.The correct recognition of the specific subtype and extension of the tumor through first line and second line radiology is essential for the surgeon, in order to effectively direct the therapeutic decisions.

scholarly journals Soft tissue masses: distribution of entities and rate of malignancy in small lesions

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Felix G. Gassert ◽  
Florian T. Gassert ◽  
Katja Specht ◽  
Carolin Knebel ◽  
Ulrich Lenze ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Benign Lesion ◽  
Maximum Diameter ◽  
Histopathological Diagnosis ◽  
Tumor Diameter ◽  
Mr Images ◽  
Tissue Mass ◽  
Malignancy Rate ◽  
Significant Difference ◽  
Soft Tissue Masses

Abstract Background Small soft tissue masses are often falsely assumed to be benign and resected with failure to achieve tumor-free margins. Therefore, this study retrospectively investigated the distribution of histopathologic diagnosis to be encountered in small soft tissue tumors (≤ 5 cm) in a large series of a tertiary referral center. Methods Patients with a soft tissue mass (STM) with a maximum diameter of 5 cm presenting at our institution over a period of 10 years, who had undergone preoperative Magnetic resonance imaging and consequent biopsy or/and surgical resection, were included in this study. A final histopathological diagnosis was available in all cases. The maximum tumor diameter was determined on MR images by one radiologist. Moreover, tumor localization (head/neck, trunk, upper extremity, lower extremity, hand, foot) and depth (superficial / deep to fascia) were assessed. Results In total, histopathologic results and MR images of 1753 patients were reviewed. Eight hundred seventy patients (49.63%) showed a STM ≤ 5 cm and were therefore included in this study (46.79 +/− 18.08 years, 464 women). Mean maximum diameter of the assessed STMs was 2.88 cm. Of 870 analyzed lesions ≤ 5 cm, 170 (19.54%) were classified as superficial and 700 (80.46%) as deep. The malignancy rate of all lesions ≤ 5 cm was at 22.41% (superficial: 23.53% / deep: 22.14%). The malignancy rate dropped to 16.49% (20.79% / 15.32%) when assessing lesions ≤ 3 cm (p = 0.007) and to 15.0% (18.18% / 13.79%) when assessing lesions ≤ 2 cm (p = 0.006). Overall, lipoma was the most common benign lesion of superficial STMs (29.41%) and tenosynovial giant cell tumor was the most common benign lesion of deep STMs (23.29%). Undifferentiated pleomorphic sarcoma was the most common malignant diagnosis among both, superficial (5.29%) and deep (3.57%) STMs. Conclusions The rate of malignancy decreased significantly with tumor size in both, superficial and deep STMs. The distribution of entities was different between superficial and deep STMs, yet there was no significant difference found in the malignancy rate.

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