This work demonstrates that 5wt% gold catalysts supported on Al2O3 and TiO2 nanopowders as well as on TiO2 nanofibers are active in the 1,2-propanediol (1,2-PDO) oxidation to lactic acid. The influence of catalysts different parameters and reaction conditions on 1,2-PDO conversion and oxidation process selectivity was studied. The best result was achieved using 5wt%Au/TiO2 catalyst over the following oxidation parameters: c0(1,2-PDO) = 0.3 mol/L, n (1,2-PDO)/n (Au) = 4000 mol/mol, p (O2) = 6 bar, c0(NaOH) = 2 mol/L, t = 60 °C: 1,2-propanediol conversion was 98 % and lactic acid selectivity 89 %.