Optimization of astaxanthin production by Phaffia rhodozyma through factorial design and response surface methodology

2001 ◽  
Vol 88 (3) ◽  
pp. 259-268 ◽  
Author(s):  
Jesús Ramı́rez ◽  
Humberto Gutierrez ◽  
Anne Gschaedler
2011 ◽  
Vol 366 ◽  
pp. 366-369
Author(s):  
Feng Gao ◽  
Rong Fu ◽  
Ming Yang Qian ◽  
Zhu Min Wang ◽  
Xiang Zhang

Response surface methodology was used to optimize the soaking Mg leaching ratio from the boron slurry screened by 25 fractional factorial design. Five effective factors such as H2SO4 concentrations, reaction time, reaction temperature and stir velocity were tested by using 25 fractional factorial design criterion and three effective factors H2SO4 concentrations, reaction time and reaction temperature showed significant effect(P2SO4 concentrations of 0.29mol/l, reaction time of 90 min and reaction temperature of 50°C. Three runs of additional confirmation experiments were conducted. The mixture magnesium leaching value was 58.20%.


2019 ◽  
Vol 281 ◽  
pp. 63-70 ◽  
Author(s):  
Tiago Linus Silva Coelho ◽  
Francislene Machado Silva Braga ◽  
Naise Mary Caldas Silva ◽  
Clecio Dantas ◽  
Cícero Alves Lopes Júnior ◽  
...  

2019 ◽  
Vol 31 (5) ◽  
pp. 1045-1048
Author(s):  
Quang Thuong Tran ◽  
Loan Thi Thanh Vu ◽  
Tram Huyen Le ◽  
Ly Thi Phuong Giang ◽  
Toyonobu Usuki

The objective of this study was to evaluate the effects of extraction parameters (ethanol concentration, extraction ratio of solvent to raw material and extraction time) on the yield of spinosin from the seeds of Ziziphus mauritiana Lam. Box-Behnken factorial design was used in association with response surface methodology. The optimal extraction conditions were an ethanol concentration of 61 %, 40 (v/w) liquid-to-solid ratio, and 2.6 h extraction time with reflux. Spinosin was purified using Diaion HP20SS as an adsorbent. The maximum spinosin yield was 1.18 mg/g raw material. Present findings can be applied to future approaches for maximizing the extraction of spinosin from Z. mauritiana Lam. seeds.


2014 ◽  
Vol 35 (4) ◽  
pp. 514-523 ◽  
Author(s):  
Tiago P. Braga ◽  
Regina C.R. Santos ◽  
Barbara M.C. Sales ◽  
Bruno R. da Silva ◽  
Antônio N. Pinheiro ◽  
...  

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