Bioactive derivatives from oleuropein by a biotransformation on Olea europaea leaf extracts

Oleaster (wild olive tree) by-products represent a renewable and low-cost source of biopolyphenols. Leaf extracts (sylv.OLE) of Algerian oleaster, locally called a’hachad (Olea europaea subsp. europaea var. sylvestris), were applied at 1 and 5% (v/w) to raw Halal minced beef (HMB) in order to test its safety and shelf-life prolongation during retail/display. The total phenolic compound content in the extract was 198.7 ± 3.6 mg gallic acid equivalent. Ten compounds were identified in the sylv.OLE by High Performance Liquid Chromatography/Diode Array Detector (HPLC/DAD), of which oleuropein was the most abundant (43.25%). Samples treated with 5% sylv.OLE had significantly higher antimicrobial and antioxidant effects than those treated with 1% extract (p < 0.05). The addition of sylv.OLE reduced psychrotrophic counts as well as the level of pathogens (Salmonella enterica ser. Enteritidis and Shiga toxin-producing Escherichia coli O157:H7). A thiobarbituric acid reactive substance (TBARS) value of 2.42 ± 0.11 was reached throughout six days of retail/display in control samples, while the addition of 5% sylv.OLE reduced TBARS value by 58% (p < 0.05). The presence of sylv.OLE at the tested concentrations did not negatively influence the overall acceptability and bitterness of HMB.

Download Full-text

Influence of drying temperature and harvesting season on phenolic content and antioxidant activity of olive ( Olea europaea ) leaf extracts

Free Radical Biology and Medicine ◽

10.1016/j.freeradbiomed.2017.04.299 ◽

2017 ◽

Vol 108 ◽

pp. S91

Author(s):

María Losada-Echeberría ◽

Amani Taamalli ◽

Vicente Micol ◽

María Herranz-López ◽

David Arráez-Román ◽

...

Keyword(s):

Antioxidant Activity ◽

Olea Europaea ◽

Phenolic Content ◽

Leaf Extracts ◽

Drying Temperature ◽

Olea Europaéa

Download Full-text

Evaluation of phenolic compounds and protective effects of olive (Olea europaea L.) leaf extracts on endothelial cells against hydrogen peroxide-induced toxicity

Journal of Research in Pharmacy ◽

10.35333/jrp.2020.198 ◽

2020 ◽

Vol 24 (4) ◽

pp. 497-507

Author(s):

Hilal TORUL ◽

Nurgün KÜÇÜKBOYACI ◽

Uğur TAMER ◽

Çimen KARASU

Keyword(s):

Hydrogen Peroxide ◽

Endothelial Cells ◽

Phenolic Compounds ◽

Olea Europaea ◽

Protective Effects ◽

Leaf Extracts ◽

Olea Europaea L ◽

Olea Europaéa

Download Full-text

The Anti-inflammatory Effect of Polyphenolics Olive Leaf Extracts Olea europaea L.

Phytothérapie ◽

10.3166/phyto-2021-0251 ◽

2021 ◽

Author(s):

Y. Aissaoui ◽

Y. Boukhari ◽

M. A. Mahi

Keyword(s):

Olea Europaea ◽

Acute Inflammation ◽

Inflammatory Activity ◽

Olive Leaves ◽

Leaf Extracts ◽

Polyphenolic Extract ◽

Significant Difference ◽

Anti Inflammatory ◽

Inflammatory Effect ◽

Olea Europaéa

This study was to evaluate the anti-inflammatory effect of the polyphenolic extract of olive leaves Olea europaea L. In vivo experiments were performed on the model of acute inflammation edema of the paw of male Wistar rats following inflammation induced by the injection of carrageenan. The anti-inflammatory effect is carried out by the injection of the polyphenolic extracts of olive leaves Olea europaea L. at different doses 50 mg/kg, 100 mg/kg and 150 mg/kg, the injection was carried out 30 min before induction of acute inflammation with carrageenan at 1%. The results obtained were compared with those of Diclofenac and those of the physiological control. Injection of carrageenan resulted in a significant increase in the claw leg volume of 46.24 ± 23.8%, 66.78 ± 29.69% and 90.31 ± 46.51%, respectively at 1 h, 2 h, and 3 h. The results showed that the inflammatory activity of the polyphenolic extracts of olive leaves was dose dependent. The 150 mg/kg Olea europaea L. extract of polyphenolic has an anti-inflammatory activity which results in an 88% decrease in edema. This decrease is significantly similar to that of Diclofenac® 97% confirmed that the polyphenolic extracts of Olea europaea L. leaves have anti-inflammatory activities comparable to that of Diclofenac® with a non-significant difference (p < 0.05), this anti-inflammatory effect remains lower than that of Diclofenac®.

Download Full-text

Evaluation of Phytochemical and Antioxidant Properties of 15 Italian Olea europaea L. Cultivar Leaves

Molecules ◽

10.3390/molecules24101998 ◽

2019 ◽

Vol 24 (10) ◽

pp. 1998 ◽

Cited By ~ 11

Author(s):

Francesca Nicolì ◽

Carmine Negro ◽

Marzia Vergine ◽

Alessio Aprile ◽

Eliana Nutricati ◽

...

Keyword(s):

Superoxide Anion ◽

Olea Europaea ◽

Antioxidant Activities ◽

Antioxidant Properties ◽

Dry Weight ◽

Total Phenolic ◽

Therapeutic Effects ◽

Leaf Extracts ◽

Olea Europaea L ◽

Olea Europaéa

Olive leaf extracts are of special interest due to their proven therapeutic effects. However, they are still considered a by-product of the table olive and the oil industries. In order to learn possible ways of exploiting this waste for health purposes, we investigated the phytochemical profiles and antioxidant activities in the leaves of 15 Italian Olea europaea L. cultivars grown in the same pedoclimatic conditions. The phenolic profiles and amounts of their seven representative compounds were analyzed using HPLC ESI/MS-TOF. The antioxidant activities were determined using three different antioxidant assays (DPPH, ORAC, and superoxide anion scavenging assay). Wide ranges of total phenolic content (11.39–48.62 g GAE kg−1 dry weight) and antioxidant activities (DPPH values: 8.67–29.89 µmol TE mg−1 dry weight, ORAC values: 0.81–4.25 µmol TE mg−1 dry weight, superoxide anion scavenging activity values: 27.66–48.92 µmol TE mg−1 dry weight) were found in the cultivars. In particular, the cultivars Itrana, Apollo, and Maurino, showed a high amount of total phenols and antioxidant activity, and therefore represent a suitable natural source of biological compounds for use in terms of health benefits.

Download Full-text

Stability effects of methyl β-cyclodextrin on Olea europaea leaf extracts in a natural deep eutectic solvent

European Food Research and Technology ◽

10.1007/s00217-018-3090-8 ◽

2018 ◽

Vol 244 (10) ◽

pp. 1783-1792 ◽

Cited By ~ 5

Author(s):

Vassilis Athanasiadis ◽

Spyros Grigorakis ◽

Stavros Lalas ◽

Dimitris P. Makris

Keyword(s):

Olea Europaea ◽

Deep Eutectic Solvent ◽

Leaf Extracts ◽

Natural Deep Eutectic Solvent ◽

Olea Europaéa

Download Full-text

The effect of olive (Olea europaea L.) phenolics and sugar on Drosophila melanogaster’s development

Animal Biology ◽

10.1163/15707563-17000162 ◽

2018 ◽

Vol 68 (4) ◽

pp. 367-385 ◽

Cited By ~ 1

Author(s):

Eda Güneş ◽

Derya Arslan Danacıoğlu

Keyword(s):

Sex Ratio ◽

Olea Europaea ◽

Negative Impact ◽

Model Organism ◽

Free Radical Scavengers ◽

Adult Longevity ◽

Glutathione S Transferase ◽

Leaf Extracts ◽

Third Stage ◽

Olea Europaéa

Abstract Olive leaves (Olea europaea L.) contain phenolics that are used for various aims and can also be utilized as free radical scavengers and as a powerful antioxidant source. In this study, our aim was to observe the effects of olive phenolics on the survival rate, development, sex ratio, and adult longevity of Drosophila melanogaster Meigen (Diptera: Drosophilidae) fed with sugar and with a sugar-free diet. The amount of malondialdehyde and the activity of glutathione S-transferase were examined with UV-VIS spectrophotometry in third-stage larvae, pupae and adults. For this purpose, dried olive fruit and leaf extracts were added at different concentrations to the insect’s sugary diets. The results reveal that 12 mg/L phenolic fruit extract and 4 M sucrose had a negative impact on the development and survival of these insects. It was also found that phenolic leaf extract and low sugar concentrations changed the sex ratio, leading to fewer females and more males. The use of phenolic fruit and phenolic leaf extracts with increased sugar-based diets raised the amount of oxidation as well as the detoxification activity in this model organism. These results demonstrate that low amounts of sugar and olive phenolics may be used as an adjunct to adult nutrients to improve the insect’s adult characteristics.

Download Full-text