High-resolution MRI and micro-FE for the evaluation of changes in bone mechanical properties during longitudinal clinical trials: application to calcaneal bone in postmenopausal women after one year of idoxifene treatment

2002 ◽  
Vol 17 (2) ◽  
pp. 81-88 ◽  
Author(s):  
B van Rietbergen ◽  
S Majumdar ◽  
D Newitt ◽  
B MacDonald
Author(s):  
Alan P. Koretsky ◽  
Afonso Costa e Silva ◽  
Yi-Jen Lin

Magnetic resonance imaging (MRI) has become established as an important imaging modality for the clinical management of disease. This is primarily due to the great tissue contrast inherent in magnetic resonance images of normal and diseased organs. Due to the wide availability of high field magnets and the ability to generate large and rapidly switched magnetic field gradients there is growing interest in applying high resolution MRI to obtain microscopic information. This symposium on MRI microscopy highlights new developments that are leading to increased resolution. The application of high resolution MRI to significant problems in developmental biology and cancer biology will illustrate the potential of these techniques.In combination with a growing interest in obtaining high resolution MRI there is also a growing interest in obtaining functional information from MRI. The great success of MRI in clinical applications is due to the inherent contrast obtained from different tissues leading to anatomical information.


2006 ◽  
Vol 22 (06) ◽  
Author(s):  
Robert Spinner ◽  
Toshiki Endo ◽  
Eric Dozois ◽  
Kimberly Amarami

2021 ◽  
Author(s):  
Karl‐Heinz Herrmann ◽  
Franziska Hoffmann ◽  
Günther Ernst ◽  
David Pertzborn ◽  
Daniela Pelzel ◽  
...  

2020 ◽  
pp. neurintsurg-2020-017053
Author(s):  
Emanuele Orru' ◽  
Miklos Marosfoi ◽  
Neil V Patel ◽  
Alexander L Coon ◽  
Christoph Wald ◽  
...  

BackgroundExisting travel restrictions limit the mobility of proctors, significantly delaying clinical trials and the introduction of new neurointerventional devices. We aim to describe in detail technical and legal considerations regarding international teleproctoring, a tool that could waive the need for in-person supervision during procedures.MethodsInternational teleproctoring was chosen to provide remote supervision during the first three intracranial aneurysm treatments with a new flow diverter (currently subject of a clinical trial) in the US. Real-time, high-resolution transmission software streamed audiovisual data to a proctor located in Canada. The software allowed the transmission of images in a de-identified, HIPAA-compliant manner.ResultsAll three flow diverters were implanted as desired by operator and proctor and without complication. The proctor could swap between images from multiple sources and reported complete spatial and situational awareness, without any significant lag or delay in communication. Procedural times and radiologic dose were similar to those of uncomplicated, routine flow diversion cases at our institution.ConclusionsInternational teleproctoring was successfully implemented in our clinical practice. Its first use provided important insights for establishing this tool in our field. With no clear horizon for lifting the current travel restrictions, teleproctoring has the potential to remove the need for proctor presence in the angiography suite, thereby allowing the field to advance through the continuation of trials and the introduction of new devices in clinical practice. In order for this tool to be used safely and effectively, highly reliable connection and high-resolution equipment is necessary, and multiple legal nuances have to be considered.


2019 ◽  
Vol 11 (24) ◽  
pp. 2893 ◽  
Author(s):  
Yi-Chun Lin ◽  
Yi-Ting Cheng ◽  
Tian Zhou ◽  
Radhika Ravi ◽  
Seyyed Hasheminasab ◽  
...  

Unmanned Aerial Vehicle (UAV)-based remote sensing techniques have demonstrated great potential for monitoring rapid shoreline changes. With image-based approaches utilizing Structure from Motion (SfM), high-resolution Digital Surface Models (DSM), and orthophotos can be generated efficiently using UAV imagery. However, image-based mapping yields relatively poor results in low textured areas as compared to those from LiDAR. This study demonstrates the applicability of UAV LiDAR for mapping coastal environments. A custom-built UAV-based mobile mapping system is used to simultaneously collect LiDAR and imagery data. The quality of LiDAR, as well as image-based point clouds, are investigated and compared over different geomorphic environments in terms of their point density, relative and absolute accuracy, and area coverage. The results suggest that both UAV LiDAR and image-based techniques provide high-resolution and high-quality topographic data, and the point clouds generated by both techniques are compatible within a 5 to 10 cm range. UAV LiDAR has a clear advantage in terms of large and uniform ground coverage over different geomorphic environments, higher point density, and ability to penetrate through vegetation to capture points below the canopy. Furthermore, UAV LiDAR-based data acquisitions are assessed for their applicability in monitoring shoreline changes over two actively eroding sandy beaches along southern Lake Michigan, Dune Acres, and Beverly Shores, through repeated field surveys. The results indicate a considerable volume loss and ridge point retreat over an extended period of one year (May 2018 to May 2019) as well as a short storm-induced period of one month (November 2018 to December 2018). The foredune ridge recession ranges from 0 m to 9 m. The average volume loss at Dune Acres is 18.2 cubic meters per meter and 12.2 cubic meters per meter within the one-year period and storm-induced period, respectively, highlighting the importance of episodic events in coastline changes. The average volume loss at Beverly Shores is 2.8 cubic meters per meter and 2.6 cubic meters per meter within the survey period and storm-induced period, respectively.


2001 ◽  
Vol 16 (supp01c) ◽  
pp. 1019-1021
Author(s):  
JOHN BELZ

The High-Resolution Fly's Eye cosmic ray observatory has been operating in monocular (stereo) mode for about three years (one year), during which time we have observed extensive airshowers with an integrated aperture of ~ 1500 km2-sr-yr (~ 400 km-sr-yr) at 5×1019 eV. We describe the HiRes experiment and the nitrogen fluorescence technique, and present data taken in both monocular and stereo modes including preliminary energy spectra.


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