FC25-05 - Revise the revised? the neuroanatomical hypothesis of panic disorder

2011 ◽  
Vol 26 (S2) ◽  
pp. 1957-1957
Author(s):  
T. Dresler
Keyword(s):  
Panic Disorder ◽  
Spectroscopic Data ◽  
Sensory Information ◽  
Panic Attacks ◽  
Brain Areas ◽  
Task Specificity ◽  
Therapeutic Consequences ◽  
Starting Point ◽  
Definition Of ◽  
Neuroendocrine Activation

Introduction/objectivesIn 2000 Gorman and colleagues published a widely cited revised version of their original neuroanatomical hypothesis of panic disorder from 1989. A “fear network” centered in the amygdala is supposed to be crucial in mediating fear-related responses. It is assumed that panic attacks result from a dysfunctional coordination of “upstream” (cortical) and “downstream” (brainstem) sensory information, resulting in heightened amygdalar activity with subsequent behavioral, autonomic, and neuroendocrine activation. The authors argue that many aspects of their revised neuroanatomical hypothesis are likely to prove incorrect, but hope it will stimulate research on anxiety disorders.MethodsWe reviewed neuroimaging studies on panic disorder to investigate in how far their results are in line with the neuroanatomical hypothesis and what inconsistencies emerge. Structural (CT, MRT), functional (PET, SPECT, fMRI, NIRS, EEG) and spectroscopic data (MRS) were considered.ResultsTo some extent studies investigating panic disorder found structurally and functionally altered brain areas that have been implicated in fear processing as supposed by the neuroanatomical hypothesis. However, inconsistencies regarding increased vs. decreased volume and increased vs. decreased activity in specific areas indicate aspects that cannot easily be explained by the hypothesis.ConclusionsThe neuroanatomical hypothesis is partially supported by empirical data that may have therapeutic consequences. However, inconsistencies should be a starting point to expand the hypothesis and modify some aspects. This may include the consideration of genetics, task-specificity and the definition of subgroups.

Sensory Substitution Devices as Advanced Sensory Tools

2018 ◽  
pp. 188-204
Author(s):  
Thomas D. Wright ◽  
Jamie Ward
Keyword(s):  
Nervous System ◽  
Sensory Information ◽  
Sensory Substitution ◽  
Considerable Effort ◽  
Conceptual Space ◽  
System P ◽  
Starting Point ◽  
Sensory Modalities ◽  
Magnetic Sense ◽  
Definition Of

There has been considerable effort devoted towards understanding sensory substitution devices in terms of their relationship to canonical sensory modalities. The approach taken in this essay is rather different, although complementary, in that we seek to define a broad conceptual space of ‘sensory tools’ in which sensory substitution devices can be situated. Such devices range from telescopes, to cochlear implants, to attempts to create a magnetic sense. One feature of these devices is that they operate at the level of ‘raw’ sensory information. As such, systems such as Braille which operate at a symbolic/conceptual level do not count as a sensory tool (or a sensory substitution device) and nor would a device such as CCTV which, although capturing raw sensory information, would not meet a conventional definition of a tool. With this approach, we hope to avoid the circularity inherent in previous attempts at defining sensory substitution and provide a better starting point to explore the effects of sensory tools, more generally, on the functioning of the nervous system.

Holism, Chinese Medicine and Systems Ideologies: Rewriting the Past to Imagine the Future

2018 ◽  
Author(s):  
Volker Scheid
Keyword(s):  
Eighteenth Century ◽  
Chinese Medicine ◽  
Medical Humanities ◽  
Science And Technology Studies ◽  
Human Beings ◽  
The Past ◽  
Starting Point ◽  
The Us ◽  
Shared Objective ◽  
Definition Of

This chapter explores the articulations that have emerged over the last half century between various types of holism, Chinese medicine and systems biology. Given the discipline’s historical attachments to a definition of ‘medicine’ that rather narrowly refers to biomedicine as developed in Europe and the US from the eighteenth century onwards, the medical humanities are not the most obvious starting point for such an inquiry. At the same time, they do offer one advantage over neighbouring disciplines like medical history, anthropology or science and technology studies for someone like myself, a clinician as well as a historian and anthropologist: their strong commitment to the objective of facilitating better medical practice. This promise furthermore links to the wider project of critique, which, in Max Horkheimer’s definition of the term, aims at change and emancipation in order ‘to liberate human beings from the circumstances that enslave them’. If we take the critical medical humanities as explicitly affirming this shared objective and responsibility, extending the discipline’s traditional gaze is not a burden but becomes, in fact, an obligation.

Digital competences of the workforce – a research topic?

2017 ◽  
Vol 23 (3) ◽  
pp. 721-734 ◽  
Author(s):  
Matthias Murawski ◽  
Markus Bick
Keyword(s):  
Research Topic ◽  
Future Research ◽  
Digital Competence ◽  
Content Type ◽  
Research Activities ◽  
Starting Point ◽  
Pros And Cons ◽  
Definition Of ◽  
The Individual ◽  
Practical Implications

Purpose Considering working in the digital age, questions on the consequences for the individual workers are, so far, often neglected. The purpose of this paper is to deal with the question of whether the digital competences of the workforce is a research topic. The authors argue for the thesis that it is indeed a research topic. Design/methodology/approach In addition to a literature analysis of the top IS, HR, and learning publications, non-scientific sources, as well as the opinions of the authors, are included. The authors’ thesis is challenged through a debate of corresponding pros and cons. Findings The definition of digital competences lacks scientific depth. Focussing on the workforce is valid, as a “lifelong” perspective is not mandatory for research. Digital competence research is a multidisciplinary task to which the IS field can make a valuable contribution. Research limitations/implications Although relevant references are included, some aspects are mainly driven by the opinions of the authors. The theoretical implications encompass a call for a scientific definition of digital competences. Furthermore, scholars should focus on the competences of the workforce, including occupations, roles, or industries. The authors conclude by providing a first proposal of a research agenda. Practical implications The practical implications include the alignment of multiple stakeholders for the design of “digital” curricula and the integration by HR departments of the construct of digital competences, e.g. for compensation matters and job requirements. Originality/value This paper is one of very few contributions in the area of the digital competences of the workforce, and it presents a starting point for future research activities.

On the Description and Definition of Human Factors/Ergonomics

1998 ◽  
Vol 42 (10) ◽  
pp. 671-674 ◽  
Author(s):  
Michael S. Wogalter ◽  
Peter A. Hancock ◽  
Patrick G. Dempsey
Keyword(s):  
Human Factors ◽  
Engineering Science ◽  
Human Factors Engineering ◽  
Lay Persons ◽  
Starting Point ◽  
Technical Report ◽  
Definition Of ◽  
Engineering Psychology

This work examines the terms most frequently used to describe our field, which has variously been named Ergonomics, Human Factors, Human Factors Engineering, and Engineering Psychology. A large number of definitions were collected, including those assembled in an earlier technical report by Licht, Polzella, and Boff (1990). First, the definitions were stripped of connector words. Second, the prefix root terms that had the same meaning were combined and third, the words were tabulated and sorted to reveal the content terms most frequently employed. These data may be used to develop core, concise definitions or longer more expository descriptions of the field. The list of terms could also be used as a starting point for the development of definitions oriented for different target audiences (e.g., lay persons vs. other engineering/science experts) as a method of disseminating information concerning what we do.

MMPI correlates of panic disorder and panic attacks

1989 ◽  
Vol 3 (2) ◽  
pp. 107-115 ◽  
Author(s):  
Janet Woodruff Borden ◽  
George A. Clum ◽  
Susan E. Broyles
Keyword(s):  
Panic Disorder ◽  
Panic Attacks

Smoking and panic attacks, panic disorder, and agoraphobia: A review of the empirical literature

2005 ◽  
Vol 25 (6) ◽  
pp. 761-789 ◽  
Author(s):  
Michael J. Zvolensky ◽  
Matthew T. Feldner ◽  
Ellen W. Leen-Feldner ◽  
Alison C. McLeish
Keyword(s):  
Panic Disorder ◽  
Panic Attacks ◽  
Empirical Literature

scholarly journals A History of Fluid Management—From “One Size Fits All” to an Individualized Fluid Therapy in Burn Resuscitation

Medicina ◽  
2021 ◽  
Vol 57 (2) ◽  
pp. 187
Author(s):  
Dorothee Boehm ◽  
Henrik Menke
Keyword(s):  
Fluid Therapy ◽  
Point Of Care ◽  
Fluid Management ◽  
Point Of Care Ultrasound ◽  
Burn Patients ◽  
Starting Point ◽  
History Of ◽  
Definition Of ◽  
Historical Developments ◽  
Burn Resuscitation

Fluid management is a cornerstone in the treatment of burns and, thus, many different formulas were tested for their ability to match the fluid requirements for an adequate resuscitation. Thereof, the Parkland-Baxter formula, first introduced in 1968, is still widely used since then. Though using nearly the same formula to start off, the definition of normovolemia and how to determine the volume status of burn patients has changed dramatically over years. In first instance, the invention of the transpulmonary thermodilution (TTD) enabled an early goal directed fluid therapy with acceptable invasiveness. Furthermore, the introduction of point of care ultrasound (POCUS) has triggered more individualized schemes of fluid therapy. This article explores the historical developments in the field of burn resuscitation, presenting different options to determine the fluid requirements without missing the red flags for hyper- or hypovolemia. Furthermore, the increasing rate of co-morbidities in burn patients calls for a more sophisticated fluid management adjusting the fluid therapy to the actual necessities very closely. Therefore, formulas might be used as a starting point, but further fluid therapy should be adjusted to the actual need of every single patient. Taking the developments in the field of individualized therapies in intensive care in general into account, fluid management in burn resuscitation will also be individualized in the near future.

The 3 C's of the Circular Economy for Food. A conceptual framework for circular design in the food system

2021 ◽  
Author(s):  
Franco Fassio
Keyword(s):  
Sustainable Development ◽  
Conceptual Framework ◽  
Circular Economy ◽  
Food System ◽  
Raw Material ◽  
Starting Point ◽  
Development Goals ◽  
Definition Of ◽  
Open Question ◽  
Circular Design

Food, the basic connecting unit of all the UN's Sustainable Development Goals, plays a crucial role in the ecological transition towards a circular economic paradigm. This paper takes scientific considerations as a starting point in order to contribute to the definition of a theoretical-operational framework in which to grow the Circular Economy for Food. This is a still-open question in a sector of the circular economy that is emerging as vital to sustainable development. The 3 C's of Capital, Cyclicality and Co-evolution offer a systemic, holistic vision of the food system's role. Within this conceptual framework, the designers can find the main boundaries of the system, within which to express their creativity. The aim must be to avoid damaging relationships with the best supplier of raw material known to humanity (Nature), respecting planetary boundaries and at the same time offering a fair space to civil society.

On the Very Idea of Civilisation

2021 ◽  
Vol 31 (2) ◽  
pp. 307-321
Author(s):  
Luke O’Sullivan ◽  
Keyword(s):  
Technological Development ◽  
Thomas Hobbes ◽  
Alternative Definition ◽  
Starting Point ◽  
Western Imperialism ◽  
Clash Of Civilisations ◽  
Definition Of ◽  
Contemporary Liberalism ◽  
Relationship Of ◽  
The Relationship

The concept of civilisation is a controversial one because it is unavoidably normative in its implications. Its historical associations with the effort of Western imperialism to impose substantive conditions of life have made it difficult for contemporary liberalism to find a definition of “civilization” that can be reconciled with progressive discourse that seeks to avoid exclusions of various kinds. But because we lack a way of identifying what is peculiar to the relationship of civilisation that avoids the problem of domination, it has tended to be conflated with other ideas. Taking Samuel Huntington's idea of a “Clash of Civilisations” as a starting point, this article argues that we suffer from a widespread confusion of civilisation with “culture,” and that we also confuse it with other ideas including modernity and technological development. Drawing on Thomas Hobbes, the essay proposes an alternative definition of civilisation as the existence of limits on how we may treat others.

The Intercity Origins of Diplomacy: Consuls, Empires, and the Sea

Diplomatica ◽  
2021 ◽  
Vol 3 (1) ◽  
pp. 147-156
Author(s):  
Halvard Leira ◽  
Benjamin de Carvalho
Keyword(s):  
Starting Point ◽  
Definition Of ◽  
Specific Definition

Abstract City diplomacy is a fairly new topic in the study of diplomacy, and, many would argue, a fairly recent empirical phenomenon. A counterpoint to this could be to reference how the alleged origin of diplomacy in Greek antiquity was city-centered, as were the earliest forms of Renaissance diplomacy in Italy. In this essay we want to probe the connections between cities and diplomacy through problematizing what has counted as diplomacy. Our starting point is that cities have always mattered to what we could analytically refer to as diplomatic practice. Being conscious of the conceptual ambiguities, we are thus not starting from a specific definition of “city diplomacy,” but from a conviction that cities have mattered and continue to matter to the practice of diplomacy.

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