Changes in hair arsenic concentration in a population exposed to heavy pollution: Follow-up investigation in Chenzhou City, Hunan Province, Southern China

2010 ◽  
Vol 22 (2) ◽  
pp. 283-289 ◽  
Author(s):  
Bin Wu ◽  
Tongbin Chen
Keyword(s):  
Southern China ◽  
Arsenic Concentration ◽  
Hunan Province ◽  
Heavy Pollution

scholarly journals Plasma Epstein-Barr virus DNA and risk of nasopharyngeal carcinoma in a prospective seropositive population

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Wen-Jie Chen ◽  
Wen-Na Xu ◽  
Hai-Yun Wang ◽  
Xiao-Xia Chen ◽  
Xue-Qi Li ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Epstein Barr Virus ◽  
Screening Program ◽  
Southern China ◽  
Incidence Rates ◽  
Cox Proportional Hazards ◽  
Barr Virus ◽  
Ebv Dna ◽  
Epstein Barr

Abstract Objective Plasma Epstein-Barr virus (EBV) DNA is considered a biomarker for nasopharyngeal carcinoma (NPC). However, its long-term role in NPC development is unclear. Materials and methods A total of 1363 participants seropositive for EBV VCA-IgA and EBNA1-IgA in a community-based NPC screening program in southern China were tested for plasma EBV DNA levels by real-time qPCR between 2008 and 2015. New NPC cases were confirmed by active follow-up approach and linkage to local cancer registry through the end of 2016. Cox proportional hazards regression analysis was performed to calculate the hazard ratios (HRs) for NPC risk with plasma EBV DNA. Results Thirty patients were newly diagnosed during a median 7.5 years follow-up. NPC incidence increased with the plasma EBV DNA load ranging from 281.46 to 10,074.47 per 100,000 person-years in participants with undetectable and ≥ 1000 copies/ml levels; the corresponding cumulative incidence rates were 1.73 and 50%. Furthermore, plasma EBV DNA loads conferred an independent risk for NPC development after adjustment for other risk factors, with HRs of 7.63 for > 3–999 copies/ml and 39.79 for ≥1000 copies/ml. However, the HRs decreased gradually after excluding NPC cases detected in the first 2 to 3 years and became statistically nonsignificant by excluding cases detected during the first 4 years. Conclusion Elevated plasma EBV DNA can predict NPC risk over 3 years. Monitoring plasma EBV DNA can be used as a complementary approach to EBV serological antibody-based screening for NPC.

scholarly journals Five-year changes in anterior segment parameters in an older population in urban southern China: the Liwan Eye Study

2019 ◽  
Vol 104 (4) ◽  
pp. 582-587 ◽  
Author(s):  
Yu Jiang ◽  
Decai Wang ◽  
Wei Wang ◽  
Feng Chen ◽  
Lanhua Wang ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Pupil Diameter ◽  
Southern China ◽  
Anterior Segment ◽  
Population Based ◽  
Light Conditions ◽  
Anterior Chamber Angle ◽  
The Mean ◽  
Angle Width

PurposeTo investigate the 5-year changes in static and dynamic anterior segment optical coherence tomography (AS-OCT) parameters and their predictors.MethodsThis was a prospective, population-based cohort study of people aged 50 years and older residing in the Liwan District, Guangzhou, China. Standardised AS-OCT scans were performed in November 2008 and November 2013 under dark and light conditions. Customised software was used to analyse horizontal AS-OCT images. Parameters in dark and measurements of light-to-dark changes were used for analyses.ResultsA total of 186 (71.8%) subjects underwent AS-OCT twice, 5 years apart and were included for analyses. The mean age in 2008 was 64.7±7.0 years, and 60.2% were women. The anterior chamber width (ACW) decreased from 11.74±0.44 mm in 2008 to 11.60±0.37 mm in 2013 (p=0.001). There was a trend towards a decrease in dynamic capacity (light-to-dark changes) in the anterior segment, with decreased iris thickness at 750 µm (ΔIT750), ΔACW, Δ anterior chamber area (ACA) and Δ pupil diameter at 5 years (all p<0.05). After adjusting for age and sex, the following baseline parameters were associated with a greater decrease rate in trabecular iris space area at 500 µm (TISA500) at 5 years: TISA500, IT750 and ACA in dark (p<0.001 for all).ConclusionsAnterior chamber angle width decreased and the amount of light-to-dark changes declined during 5-year follow-up. Subjects with greater height, wider angle width and thicker iris at baseline have greater angle narrowing at follow-up.

Rhinogobius maculagenys, A new species of freshwater goby (Teleostei: Gobiidae) from Hunan, China

Zootaxa ◽  
2018 ◽  
Vol 4476 (1) ◽  
pp. 118
Author(s):  
QIANQIAN WU ◽  
XUEJIAN DENG ◽  
YANJIE WANG ◽  
YONG LIU
Keyword(s):  
New Species ◽  
Anterior Margin ◽  
Southern China ◽  
Hunan Province ◽  
Caudal Fin ◽  
Dorsal Fin ◽  
Freshwater Goby ◽  
Single Spine ◽  
A New Species ◽  
Bright Blue

A new freshwater goby, Rhinogobius maculagenys sp. nov., was collected from Hunan Province in Southern China. This species can be distinguished from all congeners by a combination of the following features: first dorsal fin with 6 spines; second dorsal fin with a single spine and 7–9 segmented rays; anal fin with a single spine and 6–8 segmented rays; pectoral fin with 16 segmented rays; 32–34 longitudinal scales; 9–13 transverse scales; 11+16=27 vertebrae; pore ω1 missing; head and body yellowish brown; cheek and opercle yellowish brown with over 30 small orange spots, branchiostegal membrane yellow with over 10 small orange spots in males and white and spotless in females; first dorsal fin trapezoidal in males and nearly semicircular in females, with large bright blue blotch in front of second spine; spines 4 and 5 longest, rear tip extending to base of second branched ray of second dorsal fin in males when adpressed, but just reaching or not reaching anterior margin of second dorsal fin in females; caudal fin with 5–6 vertical rows of brown spots; flank with several longitudinal rows of blackish-brown spots; and belly pale white.

Prevalence and incidence of presbyopia in urban Southern China

2018 ◽  
Vol 102 (11) ◽  
pp. 1538-1542 ◽  
Author(s):  
Xiaotong Han ◽  
Pei Ying Lee ◽  
Stuart Keel ◽  
Mingguang He
Keyword(s):  
Chinese Population ◽  
Southern China ◽  
Population Based ◽  
Urban China ◽  
Cluster Sampling ◽  
Current Analysis ◽  
Random Cluster ◽  
Urban Rural ◽  
Near Visual Acuity

AimsTo investigate the prevalence and incidence of presbyopia in an urban Chinese population.Methods1817 subjects aged ≥35 years were identified by random cluster sampling in Yuexiu District, Guangzhou, China, at baseline in 2008, and all were invited for the follow-up examination in 2014. Distance and near visual acuity (VA) tests, as well as non-cycloplegic automated refraction were performed at each examination as per standardised protocol. Participants with presenting near VA ≤20/40 were further tested with add power at a standard distance of 40 cm to obtain their best-corrected near VA. Functional presbyopia was defined as near VA under presenting distance refraction correction of <20/50 and could be improved by at least one line with add power.ResultsA total of 1191 (83.5% of the 2014 follow-up) participants were included in the current analysis with a mean (SD) age of 50.4 (9.7) years, and 52.9% were female. Prevalence of functional presbyopia at baseline was 25.2% (95% CI 21.5 to 28.9) and the 6-year incidence was 42.8% (95% CI 39.4 to 50.1). Older and more hyperopic subjects had both higher prevalence and incidence of presbyopia (P<0.001). Average presbyopic correction coverage (PCC) was 87.7% at baseline and was significantly lower in myopic participants (P=0.006).ConclusionsPrevalence of functional presbyopia in urban China is relatively lower along with a higher PCC compared with previous population-based rural cohorts. We identified a high presbyopia incidence, and further studies are needed to understand longitudinal presbyopia progression as well as the urban–rural gap in presbyopia to throw light on future strategic planning.

scholarly journals Emergence and Phylogenetic Analysis of a Getah Virus Isolated in Southern China

2020 ◽  
Vol 7 ◽  
Author(s):  
Tongwei Ren ◽  
Qingrong Mo ◽  
Yuxu Wang ◽  
Hao Wang ◽  
Zuorong Nong ◽  
...  
Keyword(s):  
Southern China ◽  
Molecular Genetic ◽  
Growth Curves ◽  
Microscopic Analysis ◽  
Molecular Genetic Analysis ◽  
Hunan Province ◽  
Clinical Samples ◽  
Guangxi Province ◽  
Electron Microscopic ◽  
Getah Virus

Getah virus (GETV) has caused many outbreaks in animals in recent years. Monitoring of the virus and its related diseases is crucial to control the transmission of the virus. In the summer of 2018, we conducted routine tests on clinical samples from different pig farms in Guangxi province, South China, and isolated and characterized a GETV strain, named GX201808. Cytopathic effects were observed in BHK-21 cells inoculated with GX201808. The expression of E2 protein of GETV could be detected in virus-infected cells by indirect immunofluorescence assays. Electron microscopic analysis showed that the virus particles were spherical and ~70 nm in diameter with featured surface fibers. The multistep growth curves showed the virus propagated well in the BHK-21 cells. Molecular genetic analysis revealed that GX201808 belongs to Group 3, represented by Kochi-01-2005 isolated in Japan in 2005, and it clustered closely with the recently reported Chinese strains isolated from pigs, cattle, and foxes. A comparison of the identities of nucleotides and amino acids in the coding regions demonstrated that the GX201808 showed the highest amino acid identity (99.6%) with the HuN1 strain, a highly pathogenic isolate resulting in an outbreak of GETV infection in swine herds in Hunan province in 2017. In the present study, GETV was identified and isolated for the first time in Guangxi province of southern China, suggesting that future surveillance of this virus should be strengthened.

scholarly journals Parent Knowledge of Screening and Genetic Testing in Retinoblastoma

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Wei Xiao ◽  
Xian Ji ◽  
Huijing Ye ◽  
Huiqi Zeng ◽  
Yang Gao ◽  
...  
Keyword(s):  
Genetic Testing ◽  
Southern China ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Parent Knowledge ◽  
Face To Face ◽  
Related Information ◽  
Health Related ◽  
Oncology Unit

Purpose. To evaluate parent knowledge of screening and genetic testing for retinoblastoma and its potential correlation with demographics, clinical features, and socioeconomical factors. Methods. It was a cross-sectional study conducted at the ocular oncology unit of a tertiary ophthalmic center in Southern China. A face-to-face interview was administered to parents of retinoblastoma children during hospitalization. Parent knowledge was assessed using the sum score of a 7-item questionnaire. Demographics and socioeconomic status were collected from the interview, and clinical data were retrieved from the medical records. Results. A total of 126 parents of retinoblastoma children were included. Parents accurately answered 66.7% to 84.9% of each item in the questionnaire. Only 37 (29.4%) parents correctly answered all 7 questions. Parent knowledge was positively correlated with education, but it was not associated with patients’ laterality, sex, or household income. Physicians and the Internet were the major sources of parental health-related information. During the median follow-up of 492 days, 13 (61.9%) of 21 patients in the full-score group without genetic testing at baseline actually conducted testing during follow-up compared to 29 of 67 (43.3%) in the less-than-full-score group (P=0.136). Conclusion. Overall parent knowledge about retinoblastoma screening and genetic testing was moderate. Higher education was associated with greater parent knowledge. Future studies should validate our findings in other populations, especially in those with different cultural background and healthcare systems.

scholarly journals The precipitation chemistry and acidity over China during 2018

2019 ◽  
Vol 136 ◽  
pp. 06020 ◽  
Author(s):  
Xiaofang Jia ◽  
Jie Tang ◽  
Yong Zhang
Keyword(s):  
Acid Rain ◽  
Ph Value ◽  
Southern China ◽  
Eastern China ◽  
Precipitation Chemistry ◽  
Hunan Province ◽  
Observation Data ◽  
Rain Area ◽  
Chemistry Data ◽  
Precipitation Ph

This paper reports the acid rain observation data from 376 Acid Rain Monitoring stations and the precipitation chemistry data from 5 Global Atmosphere Watch stations of China Meteorological Administration(CMA) during 2018. The variation characteristics of acid rain in China and that of precipitation chemistry in Eastern China are discussed. The results show that the acid rain area in China is mainly distributed in the Southeast and South of China and dispersively in North and Southwest of China. Heavy acid rain area is only limited in Eastern part of Hunan province. The annual mean precipitation pH value of all stations in 2018 ranges from 3.73 to 8.07 and the national annual mean precipitation pH value is 5.94, which is higher than those of 2010-2017. The national annual mean precipitation conductivity is 47.7 μS·cm-1 with the higher conductivity in Northern China and lower in Southern China. Compared with 2010-2017, the acid rain pollution situation over China has been improving nationwide. The precipitation chemistry data shows that the concentration of sulfate is close to nitrate in precipitation and keeps decreasing in recent years.

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