Life expectancy, comorbidity and quality of life: the treatment equation in the older cancer patients

2001 ◽  
Vol 37 (2) ◽  
pp. 147-152 ◽  
Author(s):  
L. Repetto ◽  
D. Comandini ◽  
S. Mammoliti
2009 ◽  
Vol 45 (1) ◽  
pp. 19-32 ◽  
Author(s):  
Deborah Fitzsimmons ◽  
Jacqueline Gilbert ◽  
Frances Howse ◽  
Teresa Young ◽  
Juan-Ignacio Arrarras ◽  
...  

2018 ◽  
Vol 36 (15_suppl) ◽  
pp. e22017-e22017 ◽  
Author(s):  
Jurema Telles O Lima ◽  
Luiz Claudio Santos Thuler ◽  
Anke Bergmann ◽  
Barbara laffayette viana da Luz ◽  
Maria Julia Gonçalves Mello

2021 ◽  
Author(s):  
Josiane C. Vettori ◽  
Luanda G. da-Silva ◽  
Karina Pfrimer ◽  
Jordão-Junior Alceu A ◽  
Paulo Louzada-Junior ◽  
...  

Abstract Background Older advanced stage cancer patients, with changes in metabolic and nutritional status, represent an important demand for palliative care. The objective of the present study was to determine the effects of 4 weeks of chocolate consumption on the nutritional status, quality of life, body composition, oxidative stress and inflammaory activity of older cancer patients in palliative care. Methods Older cancer patients in palliative care with ambulatory monitoring were randomized to the following groups: control (CG, n = 15), intervention with 55% cocoa chocolate (IG1, n = 16) and intervention with white chocolate (IG2, n = 15) groups and evaluated before and after 4 weeks of treatment for nutritional status, food consumption, anthropometry, body composition, and laboratory parameters, and quality of life using the instrument of the European Organization for the Research and Treatment of Cancer. Results IG1 progressed with increased screening (p < 0.01) and nutritional (p = 0.04) scores on the Mini Nutritional Assessment tool. Anthropometry and body composition did not change. Regarding antioxidant capacity, reduced glutathione levels increased in IG2 (p = 0.04) and were higher than in IG1 (p < 0.01). Malondealdehyde levels were reduced in IG2 (p = 0.02) at the end of the study. Regarding quality of life, functionality improved in IG1, with a higher score in the functional domain (p = 0.03), and in the role functioning (p < 0.01) and in the social (p < 0.01) subdomains. Conclusions The consumption of chocolate with a greater cocoa content may contribute to the improvement of nutritional status and functionality among older cancer patients in palliative care. The consumption of white chocolate was associated with improved oxidative stress. Trial registration: ClinicalTrials.gov NCT04367493 - April 29, 2020. Retrospectively registered.


2015 ◽  
Vol 33 (15_suppl) ◽  
pp. e20524-e20524 ◽  
Author(s):  
Allison Magnuson ◽  
Chintan Pandya ◽  
William Dale ◽  
Lisa Lowenstein ◽  
Chunkit Fung ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Bohdan Kadlec ◽  
Jana Skrickova ◽  
Zdenek Merta ◽  
Ladislav Dusek ◽  
Jiri Jarkovsky

Patients with lung cancer experience elevated risk of venous thromboembolism. Cancer patients with thrombosis have a shorter life expectancy and the occurrence of VTE worsens the quality of life and may delay, interrupt, or completely halt the cancer therapy. In a large cohort of lung cancer patients we monitored the incidence of venous thromboembolism and we identified groups of patients with the highest risk of venous thromboembolism suitable for antithrombotic prophylaxis, which could favourably affect their morbidity and mortality.


2014 ◽  
Vol 32 (31_suppl) ◽  
pp. 184-184
Author(s):  
Marie Anne Flannery ◽  
Chintan Pandya ◽  
Mohamedtaki Abdulaziz Tejani ◽  
Charles Stewart Kamen ◽  
Allison Magnuson ◽  
...  

184 Background: Although extensive descriptive work has been conducted on the symptom experience in cancer, relatively little is known about the specific palliative care needs for geriatric oncology populations. When all age groups are studied older individuals report less symptoms and the symptom experience of older cancer patients is minimized. Utilizing data collected from two geriatric oncology referral clinics the primary aim of this study was to identify geriatric oncology patients’ symptom reports, the number of symptoms experienced, and interference reported from symptoms. Methods: Patients referred to a geriatric oncology consult clinic were asked to complete the MD Anderson Symptom Inventory (MDASI) total of 13 items. In addition all patients underwent comprehensive geriatric assessment with a battery of tests. Results: 192 patients completed the symptom inventory with a median age of 81 years (range 65-95). 94% of patients reported at least one symptom, >45% reported experiencing 10 of the 13 symptoms (mean number of symptoms =5.7, SD= 3.7). Most frequently reported symptoms were in order: drowsiness, trouble remembering, dry mouth, disturbed sleep, pain, distress, decreased appetitive, dyspnea, and sadness. Severity ratings for individual symptoms M’s= 0.3-2.5, although the complete range of 0-10 was reported. 67% of patients reported that symptoms were interfering with their quality of life, general activity level and walking ability. Conclusions: In contrast to the myth that older cancer patients have minimal symptoms, at time of referral to a geriatric oncology consultation patients report on average experiencing six symptoms which interfere with their quality of life. There is an intersection between geriatric oncology and palliative care and these descriptive findings highlight the importance of systematic symptom assessment for older individuals with cancer to identify needed symptom relief strategies.


2019 ◽  
Vol 10 (6) ◽  
pp. S76-S77
Author(s):  
I.M. Røyset ◽  
I. Saltvedt ◽  
B.H. Grønberg ◽  
T. Røsstad ◽  
S. Bergh ◽  
...  

2019 ◽  
Vol 48 (4) ◽  
pp. 030006051988810
Author(s):  
Yu Chen ◽  
Yayi He ◽  
Chao Zhao ◽  
Xuefei Li ◽  
Caicun Zhou ◽  
...  

As a consequence of the improvements in diagnostic technology along with gains in life expectancy of cancer patients, the incidence of spine metastases has increased. Spine metastases can affect the patient’s quality of life and negatively impact on their prognosis. Multidisciplinary treatments involve surgery, chemotherapy, radiosurgery and radiotherapy. Spine metastases should be treated using a multidisciplinary and integrated approach that involves spinal surgeons, medical oncologists and radiologists. More research is required to elucidate the pathological mechanisms involved in the aetiology of spine metastasis. This review describes the current situation regarding the diagnosis of spine metastasis, what is understood about the pathological development of spine metastasis and the evolution of the multidisciplinary treatments that are available for patients with spine metastases.


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