scholarly journals PIN40 ASSESSMENT OF THE CROSS-CULTURAL VALIDITY OF AN HIV SYMPTOM DISTRESS MODULE IN AN INTERNATIONAL HIV CLINICAL TRIAL

2008 ◽  
Vol 11 (3) ◽  
pp. A104-A105
Author(s):  
A Regnault ◽  
S Marfatia ◽  
M Louie ◽  
M Viala
2020 ◽  
Vol 54 (6) ◽  
pp. 1522-1533
Author(s):  
Alison Greene ◽  
Mary Elmer ◽  
Sean Ludlam ◽  
Kathyjo Shay ◽  
Sarah Bentley ◽  
...  

Abstract Objectives The Study Participant Feedback Questionnaire (SPFQ) is a patient-completed tool designed to assess patient experiences and satisfaction with aspects associated with being involved in a clinical trial. Originally developed in oncology and among English-speaking participants, the aim of the current study was to evaluate the content and cross-cultural validity of the SPFQ in other indications and non-English-speaking countries. Methods Semi-structured qualitative telephone interviews were conducted with 80 participants across eight non-English-speaking countries (in Europe, South America and Asia) who had received an investigational medicinal product as part of a clinical trial in the past three years. Interviews comprised concept elicitation to identify concepts of importance to participants’ trial experiences, and cognitive debriefing to assess understanding and perceived importance of SPFQ instructions, items and response options. Results Concept elicitation findings supported the content validity of the SPFQ. During cognitive debriefing, SPFQ instructions and the majority of items were well understood by participants. Participants generally considered the SPFQ items important to their clinical trial experience, albeit a handful of items assessed concepts that had not been experienced by trial participants or were redundant with other SPFQ items. The instructions, response options and recall period of the SPFQ were generally well understood. No country-level differences in understanding or importance were apparent. Conclusion Study findings provide evidence for the content and cross-cultural validity of the SPFQ and support implementation of the SPFQ as a means of obtaining participant feedback across global development programmes in a variety of indications.


2009 ◽  
Vol 19 (1) ◽  
pp. 9-17 ◽  
Author(s):  
Steven J. Collings ◽  
Lotten Lindblom ◽  
Sylvester N. Madu ◽  
Myung Sook Park

2020 ◽  
Vol 41 (3) ◽  
pp. 640-646
Author(s):  
Keri J S Brady ◽  
Pengsheng Ni ◽  
Gabrielle G Grant ◽  
Catherine R Thorpe ◽  
Deborah Nadler ◽  
...  

Abstract The Young Adult Burn Outcome Questionnaire (YABOQ) is a validated, English-language patient-reported outcome assessment of young adults’ recovery from burn injury across 15 scale domains. We evaluated the cross-cultural validity of a newly developed Spanish version of the YABOQ. Secondary data from English- and Spanish-speaking burn survivors (17 to 30 years of age) were obtained from the Multicenter Benchmarking Study. We conducted classic psychometric analyses and evaluated the measurement equivalence of the English and Spanish YABOQs in logistic and ordinal logistic regression differential item functioning analyses. All multi-item scales in the Spanish YABOQ demonstrated adequate reliability except the Pain and Itch scales. One item in the Perceived Appearance scale showed differential item functioning across English- and Spanish-speaking burn survivors, but the observed differential item functioning had no clinically significant impact on scale-level Perceived Appearance scores. Our findings support the cross-cultural validity of the YABOQ Physical Function, Perceived Appearance, Sexual Function, Emotion, Family Function, Family Concern, Satisfaction with Symptom Relief, Satisfaction with Role, Work Reintegration and Religion scales among English- and Spanish-speaking young adult burn survivors. This work supports the use of these English and Spanish YABOQ scales to assess the effect of therapeutic interventions on young adults’ burn outcomes in pooled analyses and to assess disparities in young adults’ burn outcomes across language groups.


Lung Cancer ◽  
2009 ◽  
Vol 64 ◽  
pp. S70
Author(s):  
F. Ataman ◽  
N. Songur ◽  
S. Kaya ◽  
C. Ozdilekcan ◽  
U. Turay ◽  
...  

1968 ◽  
Vol 23 (3_suppl) ◽  
pp. 1236-1238 ◽  
Author(s):  
E. Terry Prothro ◽  
Lutfy N. Diab

The purpose of the present study was to test the cross-cultural validity of the relationship found in Western samples between birth order and age at marriage. Data on birth order and actual age at marriage were obtained through individual interviews with 84 Arab Moslem wives in Damascus, while data on birth order and ideal best-marriage-ages were obtained from a sample of 142 undergraduate Arab students at the American University of Beirut, consisting of 74 Christians and 68 Moslems. In general, the results showed no significant differences in mean actual ages at marriage between firstborn and later born wives or husbands. Furthermore, regardless of sex, no significant differences were found between firstborn and later born ideal best-marriage-ages. These findings throw doubt on the relationship found previously between birth order and age at marriage.


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