P27 Antiangiogenic activity of combining gefitinib and rapamycin in a panel of pancreas cancer cell lines

2007 ◽  
Vol 5 (8) ◽  
pp. 31
Author(s):  
L. Pocelli ◽  
A. Azzariti ◽  
G.M. Simone ◽  
G. Gatti ◽  
A. Nicolin ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Pancreas Cancer ◽  
Cancer Cell Lines ◽  
Antiangiogenic Activity

scholarly journals Myoferlin Is a Yet Unknown Interactor of the Mitochondrial Dynamics’ Machinery in Pancreas Cancer Cells

Cancers ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1643
Author(s):  
Sandy Anania ◽  
Raphaël Peiffer ◽  
Gilles Rademaker ◽  
Alexandre Hego ◽  
Marc Thiry ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Cell Lines ◽  
Cancer Cell ◽  
Pancreas Cancer ◽  
Mitochondrial Dynamics ◽  
Mitochondrial Fission ◽  
Cancer Cell Lines ◽  
Ductal Adenocarcinoma ◽  
Mitochondrial Dynamic ◽  
Pancreatic Cancer Cells

Pancreas ductal adenocarcinoma is one of the deadliest cancers where surgery remains the main survival factor. Mitochondria were described to be involved in tumor aggressiveness in several cancer types including pancreas cancer. We have previously reported that myoferlin controls mitochondrial structure and function, and demonstrated that myoferlin depletion disturbs the mitochondrial dynamics culminating in a mitochondrial fission. In order to unravel the mechanism underlying this observation, we explored the myoferlin localization in pancreatic cancer cells and showed a colocalization with the mitochondrial dynamic machinery element: mitofusin. This colocalization was confirmed in several pancreas cancer cell lines and in normal cell lines as well. Moreover, in pancreas cancer cell lines, it appeared that myoferlin interacted with mitofusin. These discoveries open-up new research avenues aiming at modulating mitofusin function in pancreas cancer.

Molecular cytogenetic characterization of pancreas cancer cell lines reveals high complexity chromosomal alterations

2007 ◽  
Vol 118 (2-4) ◽  
pp. 148-156 ◽  
Author(s):  
C.A. Griffin ◽  
L. Morsberger ◽  
A.L. Hawkins ◽  
M. Haddadin ◽  
A. Patel ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Pancreas Cancer ◽  
Cancer Cell Lines ◽  
High Complexity ◽  
Chromosomal Alterations ◽  
Molecular Cytogenetic ◽  
Cytogenetic Characterization

797: Noggin Blocks the Osteoinductive Properties of Human Prostate Cancer Cell Lines

2006 ◽  
Vol 175 (4S) ◽  
pp. 258-258
Author(s):  
Ruth Schwaninger ◽  
Cyrill A. Rentsch ◽  
Antoinette Wetterwald ◽  
Irena Klima ◽  
Gabri Van der Pluijm ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Prostate Cancer Cell ◽  
Cancer Cell Lines ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Human Prostate Cancer Cell ◽  
Prostate Cancer Cell Lines
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