Periodontal disease, tooth loss, and cancer risk in male health professionals: a prospective cohort study

IntroductionThe cancer risk of radiation exposure in the moderate-to-high dose range has been well established. However, the risk remains unclear at low-dose ranges with protracted low-dose rate exposure, which is typical of occupational exposure. Several epidemiological studies of Korean radiation workers have been conducted, but the data were analysed retrospectively in most cases. Moreover, groups with relatively high exposure, such as industrial radiographers, have been neglected. Therefore, we have launched a prospective cohort study of all Korean radiation workers to assess the health effects associated with occupational radiation exposure.Methods and analysisApproximately 42 000 Korean radiation workers registered with the Nuclear Safety and Security Commission from 2016 to 2017 are the initial target population of this study. Cohort participants are to be enrolled through a nationwide self-administered questionnaire survey between 24 May 2016 and 30 June 2017. As of 31 March 2017, 22 982 workers are enrolled in the study corresponding to a response rate of 75%. This enrolment will be continued at 5-year intervals to update information on existing study participants and recruit newly hired workers. Survey data will be linked with the national dose registry, the national cancer registry, the national vital statistics registry and national health insurance data via personal identification numbers. Age-specific and sex-specific standardised incidence and mortality ratios will be calculated for overall comparisons of cancer risk. For dose–response assessment, excess relative risk (per Gy) and excess absolute risk (per Gy) will be estimated with adjustments for birth year and potential confounders, such as lifestyle factors and socioeconomic status.Ethics and disseminationThis study has received ethical approval from the institutional review board of the Korea Institute of Radiological and Medical Sciences (IRB No. K-1603-002-034). All participants provided written informed consent prior to enrolment. The findings of the study will be disseminated through scientific peer-reviewed journals and be provided to the public, including radiation workers, via the study website (http://www.rhs.kr/) and onsite radiation safety education.

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The association between recreational screen time and cancer risk: findings from the UK Biobank, a large prospective cohort study

International Journal of Behavioral Nutrition and Physical Activity ◽

10.1186/s12966-020-00997-6 ◽

2020 ◽

Vol 17 (1) ◽

Author(s):

Ruth F. Hunter ◽

Jennifer M. Murray ◽

Helen G. Coleman

Keyword(s):

Cohort Study ◽

Cancer Risk ◽

Prospective Cohort Study ◽

Screen Time ◽

Prospective Cohort ◽

Uk Biobank ◽

Large Prospective Cohort Study ◽

The Uk ◽

Large Prospective Cohort

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Red meat consumption is associated with an increased overall cancer risk: a prospective cohort study in Korea

British Journal Of Nutrition ◽

10.1017/s0007114514000683 ◽

2014 ◽

Vol 112 (2) ◽

pp. 238-247 ◽

Cited By ~ 26

Author(s):

Gyung-Ah Wie ◽

Yeong-Ah Cho ◽

Hyun-hee Kang ◽

Kyoung-A Ryu ◽

Min-Kyoung Yoo ◽

...

Keyword(s):

Risk Factors ◽

Cancer Research ◽

Cohort Study ◽

Cancer Risk ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Meat Consumption ◽

Red Meat ◽

Dietary Factors ◽

Risk Of Cancer

Cancer is a leading cause of death, and the dietary pattern in Korea is changing rapidly from a traditional Korean diet to a Westernised diet. In the present study, we investigated the effects of dietary factors on cancer risk with a prospective cohort study. Among 26 815 individuals who participated in cancer screening examinations from September 2004 to December 2008, 8024 subjects who completed a self-administered questionnaire concerning demographic and lifestyle factors, and a 3 d food record were selected. As of September 2013, 387 cancer cases were identified from the National Cancer Registry System, and the remaining individuals were included in the control group. The hazard ratio (HR) of cancer for the subjects older than or equal to 50 years of age was higher (HR 1·80, 95 % CI 1·41, 2·31; P< 0·0001) than that for the other subjects. Red meat consumption, Na intake and obesity (BMI ≥ 25 kg/m2) were positively associated with overall cancer incidence in men (HR 1·41, 95 % CI 1·02, 1·94; P= 0·0382), gastric cancer (HR 2·34, 95 % CI 1·06, 5·19; P= 0·0365) and thyroid cancer (HR 1·56, 95 % CI 1·05, 2·31; P= 0·0270), respectively. Participants who had at least three dietary risk factors among the high intakes of red meat and Na, low intakes of vegetables and fruits, and obesity suggested by the World Cancer Research Fund/American Institute for Cancer Research at baseline tended to have a higher risk of cancer than the others (HR 1·26, 95 % CI 0·99, 1·60; P= 0·0653). In summary, high intakes of red meat and Na were significant risk factors of cancer among Koreans.

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