scholarly journals COVID-19 seroprevalence among healthcare workers in a low prevalence region

2020 ◽  
pp. 1-8
Author(s):  
Emily J. Godbout ◽  
Rachel Pryor ◽  
Mary Harmon ◽  
Alison Montpetit ◽  
Joan Greer ◽  
...  
Keyword(s):  
Healthcare Workers ◽  
Low Prevalence

scholarly journals Effect of school reopening on SARS-CoV-2 incidence in a low-prevalence region: Prospective SARS-CoV-2 testing in healthcare workers with primary school-attending children versus without children living at home

2021 ◽  
pp. 175717742110124
Author(s):  
Melvin Frie ◽  
Lisa M Havinga ◽  
Janneke Wiersema-Buist ◽  
Charlotte G Veldman ◽  
Marjan JT de Vries ◽  
...  
Keyword(s):  
Cohort Study ◽  
Population Density ◽  
Severe Acute Respiratory Syndrome ◽  
Primary School ◽  
Primary Schools ◽  
Healthcare Workers ◽  
Regional Strategies ◽  
Low Prevalence ◽  
At Home

Coronavirus disease 2019 (COVID-19) often presents asymptomatically or milder in children compared to adults. The role of young children in the transmission of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) remains largely unknown. In the Netherlands, the first action of loosening the partial lockdown that had been implemented to reduce SARS-CoV-2 transmission was the reopening of primary schools on 1 May 2020. We subsequently conducted a prospective cohort study among healthcare workers (HCWs) with primary school-attending children versus HCWs without children living at home. We tested each HCW three times for SARS-CoV-2 from May 20 to June 15 2020 at 1-week intervals. In total, 832 nasopharyngeal swabs were taken from 283 HCWs with primary school-attending children living at home and 864 nasopharyngeal swabs from 285 HCWs without children living at home. All nasopharyngeal swabs tested negative for SARS-CoV-2. In our region with a low population density and low SARS-CoV-2 prevalence, reopening of primary schools did not lead to an increase in infections. The results of this study may serve as an example for the implementation of regional strategies to reduce SARS-CoV-2 transmission in countries with large variations in both population density and SARS-CoV-2 prevalence.

Low prevalence of subclinical severe acute respiratory syndrome-associated coronavirus infection among hospital healthcare workers in Hong Kong

2005 ◽  
Vol 37 (6-7) ◽  
pp. 500-503 ◽  
Author(s):  
Thomas Sik To Lai ◽  
Tak Keung Ng ◽  
Wing Hong Seto ◽  
Loretta Yam ◽  
Kin Ip Law ◽  
...  
Keyword(s):  
Hong Kong ◽  
Severe Acute Respiratory Syndrome ◽  
Healthcare Workers ◽  
Coronavirus Infection ◽  
Low Prevalence

scholarly journals Assessment of SARS-CoV-2 Infection among Healthcare Workers of a German COVID-19 Treatment Center

2021 ◽  
Vol 18 (13) ◽  
pp. 7057
Author(s):  
Lionel Larribère ◽  
Jelizaveta Gordejeva ◽  
Lisa Kuhnhenn ◽  
Maximilian Kurscheidt ◽  
Monika Pobiruchin ◽  
...  
Keyword(s):  
Early Phase ◽  
Healthcare Workers ◽  
Treatment Center ◽  
Patient Exposure ◽  
Increased Risk ◽  
History Of ◽  
High Level ◽  
Low Prevalence

To date, more than 160 million people have been infected with COVID-19 worldwide. In the present study, we investigated the history of SARS-CoV-2 infection among 3067 healthcare workers (HCW) in a German COVID-19 treatment center during the early phase of the pandemic (July 2020) based on the seroprevalence of SARS-CoV-2 antibodies and self-reported previous PCR results. The results demonstrate a low prevalence of SARS-CoV-2 infection (n = 107 [3.5%]) with no increased risk for employees with a high level of patient exposure in general or working in COVID-19-confined areas in particular. This suggests that the local hygiene standards implemented in our hospital during the first wave of COVID-19 pandemic were effective in preventing patient-to-HCW transmission. No evidence for highly mobile staff serving as a vector for SARS-CoV-2 transmission could be found. In addition, impairment of smell and/or taste was strongly associated with SARS-CoV-2 history.

scholarly journals Prevalence of IgG antibodies against SARS-CoV-2 among healthcare workers in a tertiary pediatric hospital in Poland

2020 ◽  
Author(s):  
Beata Kasztelewicz ◽  
Katarzyna Janiszewska ◽  
Julia Burzyńska ◽  
Emilia Szydłowska ◽  
Marek Migdał ◽  
...  
Keyword(s):  
Healthcare Workers ◽  
Infection Prevention And Control ◽  
Serological Response ◽  
Igg Antibodies ◽  
Pediatric Hospital ◽  
Public Health Response ◽  
Health Response ◽  
Response Measures ◽  
Low Prevalence ◽  
And Control

AbstractData on prevalence of SARS-CoV-2 antibody in healthcare workers (HCWs) is scare, especially in pediatric settings. The purpose of this study was to evaluate the SARS-CoV-2 IgG-positivity among HCWs of a tertiary pediatric hospital. In addition, follow-up of serological response in the subgroup of seropositive HCWs was performed, to get some insight on persistence of IgG antibodies to SARS-CoV-2. Free, voluntary SARS-CoV-2 IgG testing was made available to HCWs of the Children’s Memorial Health Institute in Warsaw (Poland). Plasma samples were collected between July 1 and August 9, 2020 and tested using the Abbott SARS-CoV-2 IgG assay. Of 2282 eligible participants, 1879 (82.3%) HCWs volunteered to undergo testing. Sixteen HCWs tested positive for SARS-CoV-2 IgG, corresponding to the seroprevalence of 0.85%. Among seropositive HCWs, three had confirmed COVID-19. Of note, 8 (50%) seropositive HCWs reported neither symptoms nor unprotected contact with confirmed SARS-CoV-2 cases in the previous months. A decline in the IgG index was observed at median time of 86.5 days (range:84-128 days) after symptom onset or RT-PCR testing. The nationwide public health response measures together with infection prevention and control practices implemented at the hospital level, at the beginning of the COVID-19 pandemic, might explain a low seroprevalence. Further studies are warranted to elucidate the duration of anti-SARS-CoV-2 antibodies, as well as the correlation between seropositivity and protective immunity against reinfection. Regardless of the persistence of antibodies and their protective properties, such low prevalence indicates that this population is vulnerable to a second wave of the COVID-19 pandemic.

scholarly journals Seroprevalence of Antibodies against SARS COV- 2 among Health Care Workers at Tertiary Care Hospital, Uttarakhand: A Retrospective study

2021 ◽  
Author(s):  
Amit K Saini ◽  
Prasan Kumar Panda ◽  
Yogesh Arvind Bahurupi ◽  
Balram Omar ◽  
Akhil T ◽  
...  
Keyword(s):  
Health Care ◽  
Retrospective Study ◽  
Health Care Workers ◽  
Healthcare Workers ◽  
Tertiary Care ◽  
Care Hospital ◽  
Igg Antibodies ◽  
Care Institute ◽  
Care Workers ◽  
Low Prevalence

Abstract Background: The number of confirmed SARS-CoV-2 infections is vastly underestimated. In this context, Seroprevalence surveys are of utmost importance to assess the proportion of the population that has already developed antibodies against the virus and might potentially be protected against subsequent infection. Health care workers face greater risk of developing SARS-CoV-2. Therefore, present retrospective study was undertaken to estimate the prevalence of antibodies against SARS-CoV-2 among healthcare workers at tertiary care institute, Uttarakhand. Material and Methods : Data was gathered from Hospital records of 704 healthcare workers admitted at COVID 19 Unit and attended Covid-OPD of tertiary care institute, Uttarakhand in-between 15th July to 14th Aug 2020. Result: Out of the 704 recruited participants, 14 (1.99%) were seropositive for IgG antibodies against SARS-CoV-2. The cumulative prevalence of SARS-CoV-2 infection (presence of antibodies or past or current positive RT-PCR) was 4.40%. Conclusion: The present study shows a low prevalence of SARS-CoV-2 IgG antibodies among health care workers. In addition, posting in COVID-19-positive areas was not associated with increased seropositivity. More studies are warranted to assess IgG/IgM antibodies against SARS-CoV-2 among those HCW who are exposed to COVID-19 patients.

scholarly journals Seroprevalence of Antibodies to SARS-CoV-2 in Healthcare Workers in Non-epidemic Region: A Hospital Report in Iwate Prefecture, Japan

2020 ◽  
Author(s):  
Akihiro Nakamura ◽  
Ryoichi Sato ◽  
Sanae Ando ◽  
Natsuko Oana ◽  
Eiji Nozaki ◽  
...  
Keyword(s):  
Healthcare Workers ◽  
Social Issues ◽  
Point Of Care ◽  
Serum Samples ◽  
Lower Specificity ◽  
Epidemic Area ◽  
Prefectural Central Hospital ◽  
Qualitative Test ◽  
Low Prevalence ◽  
Iwate Prefecture

AbstractBackgroundAs of June 18, 2020, Iwate is the only one of 47 prefectures in Japan with no confirmed coronavirus disease 2019 (COVID-19) cases. Serological survey for COVID-19 antibodies is crucial in area with low prevalence as well as epidemic area when addressing health and social issues caused by COVID-19.MethodsSerum samples from healthcare workers (n = 1,000, mean 40 ± 11 years) of Iwate Prefectural Central Hospital, Iwate, Japan were tested for the prevalence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies. Two laboratory-based quantitative tests (Abbott’s and Roche’s immunoassays) and one point-of-care (POC) qualitative test performed simultaneously. Sensitivity and specificity were 100%, 99.6% in Abbott’s immunoassay; 100%, 99.8% in Roche’s immunoassay; 97.8%, 94.6% in Alfa POC test, respectively.ResultsThe laboratory-based quantitative tests showed positive in 4 of 1,000 samples (0.4%) (95% CI: 0.01 to 0.79): 4/1,000 (0.4%) (95% CI: 0.01 to 0.79) in Abbott; 0/1,000 (0%) in Roche. Positive samples were not detected for both Abbott’s and Roche’s immunoassays. The POC qualitative test showed positive in 33 of 1,000 samples (3.3%) (95% CI: 2.19 to 4.41). There were no samples with simultaneous positive reaction for two quantitative tests and a POC test.ConclusionsInfected COVID-2 cases were not confirmed by a retrospective serological study in healthcare workers of our hospital. The POC qualitative tests with lower specificity have the potential for higher false positive reactions than the laboratory-based quantitative tests in areas with very low prevalence of COVID-19.

Very low prevalence of active HCV infection among healthcare workers in a regional reference hospital of Tuscany, Italy

2019 ◽  
Vol 51 ◽  
pp. e63
Author(s):  
P. Colombatto ◽  
G. Guglielmi ◽  
F. Oliveri ◽  
B. Coco ◽  
F. Caldi ◽  
...  
Keyword(s):  
Healthcare Workers ◽  
Hcv Infection ◽  
Reference Hospital ◽  
Low Prevalence ◽  
Regional Reference

scholarly journals Sero-Prevalence of SARS-CoV-2 Antibodies in High-Risk Populations in Vietnam

2021 ◽  
Vol 18 (12) ◽  
pp. 6353
Author(s):  
Tasnim Hasan ◽  
Thach Ngoc Pham ◽  
Thu Anh Nguyen ◽  
Hien Thi Thu Le ◽  
Duyet Van Le ◽  
...  
Keyword(s):  
High Risk ◽  
Healthcare Workers ◽  
Close Contact ◽  
Contact Tracing ◽  
Community Members ◽  
Prevalence Survey ◽  
Household Contacts ◽  
Antibody Positivity ◽  
High Risk Populations ◽  
Low Prevalence

As a response to the coronavirus disease 2019 (COVID-19) pandemic, Vietnam enforced strict quarantine, contact tracing and physical distancing policies resulting in one of the lowest numbers of individuals infected with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) globally. This study aimed to determine the prevalence of SARS-CoV-2 antibody positivity among high-risk populations in Vietnam. A prevalence survey was undertaken within four communities in Vietnam, where at least two COVID-19 cases had been confirmed. Participants were classified according to the location of exposure: household contacts, close contacts, community members, and healthcare workers (HCWs) responsible for treating COVID-19 cases. Participants completed a baseline questionnaire and SARS-CoV-2 IgG antibodies were quantified using a commercial assay. A total of 3049 community members and 149 health care workers consented to the study. Among 13 individuals who were seropositive (0.4%), five household contacts (5/27, 18.5%), one close contact (1/53, 1.9%), and seven community members (7/2954, 0.2%) had detectable SARS-CoV-2 antibodies. All HCWs were negative for SARS-CoV-2 antibodies. Participants were tested a median of 15.1 (interquartile range from 14.9 to 15.2) weeks after exposure. Our study found a low prevalence of SARS-CoV-2 antibodies in high-risk communities and healthcare workers in communities in Vietnam with known COVID-19 cases.

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