scholarly journals THE LOGICS OF DOUBLE PROOF IN PROOF OF CONCEPT: A DESIGN THEORY-BASED MODEL OF EXPERIMENTATION IN THE UNKNOWN

2021 ◽  
Vol 1 ◽  
pp. 3051-3060
Author(s):  
Caroline Jobin ◽  
Sophie Hooge ◽  
Pascal Le Masson
Keyword(s):  
Design Theory ◽  
Design Framework ◽  
Proof Of Concept ◽  
Design Logic

AbstractThe literature on design distinguishes between exploration-based experimentation and validation-based experimentation. This typology relies on an assumption that exploration and validation cannot and should not be performed simultaneously in the same experimentation. By contrast, some practitioners, such as les Sismo, propose that proof of concept might combine these two logics. This raises the question of what design logic might enable this type of combination of exploration and validation. We first use design theory to build an experimentation design framework. This framework highlights a typology of proof logics in experimentation related to proof of the known and proof of the unknown. Second, we show that these proof models are supported by les Sismo's cases and describe a diversity of arrangements of exploration and validation mechanisms: sequential, parallel, and combinational. Through the formalisation of proof of concept as a double proof (proof of the known and proof of the unknown), we show that proof of concept can be more than a tool for the go/no-go decision by gradually validating propositions, questioning the relevance of propositions, and discovering new propositions to be investigated and tested.

scholarly journals THE APPLICATION OF NORMAN’S THREE LEVELS DESIGN-THEORY FOR ARTEFACT ANALYSIS OF CULTURAL RELATED DESIGN PROCESS

2020 ◽  
Vol 3 (1) ◽  
pp. 21-30
Author(s):  
Wean Ting Cheng ◽  
Musdi Shanat
Keyword(s):  
Design Process ◽  
Design Theory ◽  
Online Survey ◽  
Global Market ◽  
Cultural Value ◽  
Proof Of Concept ◽  
Local Identity ◽  
Framework Model ◽  
Process Framework ◽  
Cultural Element

Culture always associate with human activity which could give an identity. Any culture that associate with materials and objects is an aid to the creation of lasting identities. The culture will suffer loss and extinction due to less attention and preservation. In reality, designers seem less to care in injecting the cultural value in their creation and facing hardship in translating a culture object into a product. Designing a product with a cultural element could emphasis its sentimental and commercial value in the global market. Therefore, this paper aims at proposing a design process framework on how culture can be employed to generate and create product. The proposed framework explains how a culture object can inspire designers to create a product with the intervention of Norman’s Three levels of Design theory. The Artefact Analysis and online survey are used to obtain the finding and creating a proof of concept that the proposed framework model capable to provide valuable references for designing a culture-inspired product. On the other hand, the local identity could be brought up globally through culture-inspired products.

Direct measurement of electron-diffraction-pattern intensities using an energy loss spectrometer

1989 ◽  
Vol 47 ◽  
pp. 668-669
Author(s):  
A. G. Jackson ◽  
M. Rowe
Keyword(s):  
Thermal Effects ◽  
Dynamic Range ◽  
Scattering Amplitude ◽  
Dynamical Theory ◽  
Site Symmetry ◽  
Proof Of Concept ◽  
Parallel Acquisition ◽  
Kinematic Approximation ◽  
Speed Up ◽  
Structure Calculations

Diffraction intensities from intermetallic compounds are, in the kinematic approximation, proportional to the scattering amplitude from the element doing the scattering. More detailed calculations have shown that site symmetry and occupation by various atom species also affects the intensity in a diffracted beam. [1] Hence, by measuring the intensities of beams, or their ratios, the occupancy can be estimated. Measurement of the intensity values also allows structure calculations to be made to determine the spatial distribution of the potentials doing the scattering. Thermal effects are also present as a background contribution. Inelastic effects such as loss or absorption/excitation complicate the intensity behavior, and dynamical theory is required to estimate the intensity value.The dynamic range of currents in diffracted beams can be 104or 105:1. Hence, detection of such information requires a means for collecting the intensity over a signal-to-noise range beyond that obtainable with a single film plate, which has a S/N of about 103:1. Although such a collection system is not available currently, a simple system consisting of instrumentation on an existing STEM can be used as a proof of concept which has a S/N of about 255:1, limited by the 8 bit pixel attributes used in the electronics. Use of 24 bit pixel attributes would easily allowthe desired noise range to be attained in the processing instrumentation. The S/N of the scintillator used by the photoelectron sensor is about 106 to 1, well beyond the S/N goal. The trade-off that must be made is the time for acquiring the signal, since the pattern can be obtained in seconds using film plates, compared to 10 to 20 minutes for a pattern to be acquired using the digital scan. Parallel acquisition would, of course, speed up this process immensely.

Design Theory

1985 ◽  
Author(s):  
D. R. Hughes ◽  
F. Piper
Keyword(s):  
Design Theory

Remote Echocardiography: Proof of Concept for Support of National Disasters, Combat and Humanitarian Mission

2002 ◽  
Author(s):  
Sheri Yvonne Nottestad Boyd ◽  
Linda L. Huffer ◽  
Terry D. Bauch ◽  
James L. Furgerson
Keyword(s):  
Proof Of Concept ◽  
Humanitarian Mission

Model, simulation and experiments for a Buoyancy Organic Rankine Cycle

2020 ◽  
Vol 92 (1) ◽  
pp. 10906
Author(s):  
Jeroen Schoenmaker ◽  
Pâmella Gonçalves Martins ◽  
Guilherme Corsi Miranda da Silva ◽  
Julio Carlos Teixeira
Keyword(s):  
Model Simulation ◽  
Organic Rankine Cycle ◽  
Thermodynamic Cycle ◽  
Rankine Cycle ◽  
Test Body ◽  
Working Fluid ◽  
Proof Of Concept ◽  
Energy Scenario ◽  
New Type ◽  
Fluid Reservoir

Organic Rankine Cycle (ORC) systems are increasingly gaining relevance in the renewable and sustainable energy scenario. Recently our research group published a manuscript identifying a new type of thermodynamic cycle entitled Buoyancy Organic Rankine Cycle (BORC) [J. Schoenmaker, J.F.Q. Rey, K.R. Pirota, Renew. Energy 36, 999 (2011)]. In this work we present two main contributions. First, we propose a refined thermodynamic model for BORC systems accounting for the specific heat of the working fluid. Considering the refined model, the efficiencies for Pentane and Dichloromethane at temperatures up to 100 °C were estimated to be 17.2%. Second, we show a proof of concept BORC system using a 3 m tall, 0.062 m diameter polycarbonate tube as a column-fluid reservoir. We used water as a column fluid. The thermal stability and uniformity throughout the tube has been carefully simulated and verified experimentally. After the thermal parameters of the water column have been fully characterized, we developed a test body to allow an adequate assessment of the BORC-system's efficiency. We obtained 0.84% efficiency for 43.8 °C working temperature. This corresponds to 35% of the Carnot efficiency calculated for the same temperature difference. Limitations of the model and the apparatus are put into perspective, pointing directions for further developments of BORC systems.

Indocyanine green-augmented diode laser therapy of telangiectatic and reticular leg veins: a clinical proof-of-concept trial

2012 ◽  
Vol 25 (01) ◽  
Author(s):  
A Klein ◽  
G Shafirstein ◽  
E Kohl ◽  
W Bäumler ◽  
M Landthaler ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Laser Therapy ◽  
Diode Laser ◽  
Proof Of Concept

Evaluation einer als Proof-of-Concept entwickelten MRT-kompatiblen und röntgentransparenten Knochenbohrmaschine

2012 ◽  
Vol 184 (S 01) ◽  
Author(s):  
FV Güttler ◽  
K Winterwerber ◽  
C Gross ◽  
A Heinrich ◽  
M de Bucourt ◽  
...  
Keyword(s):  
Proof Of Concept

Besser als Genexpressionstests?

2018 ◽  
Vol 09 (02) ◽  
pp. 65-66
Author(s):  
Alexander Kretzschmar
Keyword(s):  
New York ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Proof Of Concept ◽  
Zirkulierende Tumorzellen

Zirkulierende Tumorzellen (Circulating Tumor Cells; CTC) sind Prädiktoren von Spät-rezidiven bei Frauen mit einem Hormonrezeptor-positiven (HR-positiv), HER2-negativen frühen Mammakarzinom. Dies ergab eine Proof-of-Concept-Studie, die von Dr. Joseph Sparano, New York, auf dem SABCS 2017 vorgestellt wurde. Spätrezidive machen etwa die Hälfte aller Östrogenrezeptor-positiven Rezidive aus. Genexpressionstests können zwar das Risiko eines Rezidivs insgesamt quantifizieren. Sparanos Arbeitsgruppe glaubt aber, dass CTC bessere Biomarker für Spätrezidive sind.

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