Dissimilar Effects of Thalidomide in Dizygotic Twins

1980 ◽  
Vol 29 (4) ◽  
pp. 295-297 ◽  
Author(s):  
Márcia Schmidt ◽  
Francisco M. Salzano
Keyword(s):  
In Utero ◽  
The Other ◽  
Dizygotic Twin ◽  
Duodenal Stenosis ◽  
Left Hand ◽  
Dizygotic Twins ◽  
The Right ◽  
Triphalangeal Thumb

Among 93 cases of thalidomide embryopathy ascertained in Brazil, one pair of female dizygotic twins was found. One of them presented complete paraxial hemimelia in the right arm while the other showed a triphalangeal thumb at the left hand and had duodenal stenosis. Of the eight dizygotic twin pairs exposed to thalidomide in utero described thus far, only four were concordant for the type of malformation.

scholarly journals Handedness in twins: meta-analyses

2022 ◽  
Vol 10 (1) ◽  
Author(s):  
Lena Sophie Pfeifer ◽  
Judith Schmitz ◽  
Marietta Papadatou-Pastou ◽  
Jutta Peterburs ◽  
Silvia Paracchini ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Odds Ratio ◽  
Meta Analysis ◽  
Dizygotic Twin ◽  
Odds Ratios ◽  
Moderating Variables ◽  
Left Hand ◽  
Dizygotic Twins ◽  
The Right ◽  
Meta Analyses

Abstract Background In the general population, 10.6% of people favor their left hand over the right for motor tasks. Previous research suggests higher prevalence of atypical (left-, mixed-, or non-right-) handedness in (i) twins compared to singletons, and in (ii) monozygotic compared to dizygotic twins. Moreover, (iii) studies have shown a higher rate of handedness concordance in monozygotic compared to dizygotic twins, in line with genetic factors playing a role for handedness. Methods By means of a systematic review, we identified 59 studies from previous literature and performed three sets of random effects meta-analyses on (i) twin-to-singleton Odds Ratios (21 studies, n = 189,422 individuals) and (ii) monozygotic-to-dizygotic twin Odds Ratios (48 studies, n = 63,295 individuals), both times for prevalence of left-, mixed-, and non-right-handedness. For monozygotic and dizygotic twin pairs we compared (iii) handedness concordance Odds Ratios (44 studies, n = 36,217 twin pairs). We also tested for potential effects of moderating variables, such as sex, age, the method used to assess handedness, and the twins’ zygosity. Results We found (i) evidence for higher prevalence of left- (Odds Ratio = 1.40, 95% Confidence Interval = [1.26, 1.57]) and non-right- (Odds Ratio = 1.36, 95% Confidence Interval = [1.22, 1.52]), but not mixed-handedness (Odds Ratio = 1.08, 95% Confidence Interval = [0.52, 2.27]) among twins compared to singletons. We further showed a decrease in Odds Ratios in more recent studies (post-1975: Odds Ratio = 1.30, 95% Confidence Interval = [1.17, 1.45]) compared to earlier studies (pre-1975: Odds Ratio = 1.90, 95% Confidence Interval = [1.59–2.27]). While there was (ii) no difference between monozygotic and dizygotic twins regarding prevalence of left- (Odds Ratio = 0.98, 95% Confidence Interval = [0.89, 1.07]), mixed- (Odds Ratio = 0.96, 95% Confidence Interval = [0.46, 1.99]), or non-right-handedness (Odds Ratio = 1.01, 95% Confidence Interval = [0.91, 1.12]), we found that (iii) handedness concordance was elevated among monozygotic compared to dizygotic twin pairs (Odds Ratio = 1.11, 95% Confidence Interval = [1.06, 1.18]). By means of moderator analyses, we did not find evidence for effects of potentially confounding variables. Conclusion We provide the largest and most comprehensive meta-analysis on handedness in twins. Although a raw, unadjusted analysis found a higher prevalence of left- and non-right-, but not mixed-handedness among twins compared to singletons, left-handedness was substantially more prevalent in earlier than in more recent studies. The single large, recent study which included birth weight, Apgar score and gestational age as covariates found no twin-singleton difference in handedness rate, but these covariates could not be included in the present meta-analysis. Together, the secular shift and the influence of covariates probably make it unsafe to conclude that twinning has a genuine relationship to handedness.

§ XI.—Hellenistic Mycenae

1923 ◽  
Vol 25 ◽  
pp. 408-428
Author(s):  
C. A. Boethius
Keyword(s):  
Common Type ◽  
The Other ◽  
The South ◽  
Left Hand ◽  
The Right

Among the ruins of the Hellenistic buildings at the south end of the Great Ramp, in the fourth or southern chamber (Pl. I. 34), three fragments of a stele (now in the Nauplia Museum) were found. The stele is of a simple and common type, and is made of the same white limestone as the other Mycenaean stele found by Tsountas, which it closely resembles even in its weathering. Except for the top left-hand corner and a gap on the right side the whole stele is preserved. It is ·969 m. in height, ·41–·436 m. in breadth (·41 m. at the ninth line of the inscription) and ·11–·125 m. thick. At the top there is a plain frieze, ·065 m. high : ·02 m. below the frieze begins an inscription which fills twenty lines and ends ·50 m. above the bottom of the stele. The letters are ·008–·01 m. high. The space between the lines is ·009–·011 m. The surface of the stone is very much worn, and it was consequently difficult to make out the letters and their accurate forms. The sketch (Fig. 93) shows the arrangement of the text.

scholarly journals Handedness results from complementary hemispheric dominance, not global hemispheric dominance: evidence from mechanically coupled bilateral movements

2018 ◽  
Vol 120 (2) ◽  
pp. 729-740 ◽  
Author(s):  
Elizabeth J. Woytowicz ◽  
Kelly P. Westlake ◽  
Jill Whitall ◽  
Robert L. Sainburg
Keyword(s):  
Motor Control ◽  
Dynamic Control ◽  
The Other ◽  
Hemispheric Dominance ◽  
Control Mechanisms ◽  
Left Hand ◽  
Right Hand ◽  
Other Hand ◽  
Task Component ◽  
The Right

Two contrasting views of handedness can be described as 1) complementary dominance, in which each hemisphere is specialized for different aspects of motor control, and 2) global dominance, in which the hemisphere contralateral to the dominant arm is specialized for all aspects of motor control. The present study sought to determine which motor lateralization hypothesis best predicts motor performance during common bilateral task of stabilizing an object (e.g., bread) with one hand while applying forces to the object (e.g., slicing) using the other hand. We designed an experimental equivalent of this task, performed in a virtual environment with the unseen arms supported by frictionless air-sleds. The hands were connected by a spring, and the task was to maintain the position of one hand while moving the other hand to a target. Thus the reaching hand was required to take account of the spring load to make smooth and accurate trajectories, while the stabilizer hand was required to impede the spring load to keep a constant position. Right-handed subjects performed two task sessions (right-hand reach and left-hand stabilize; left-hand reach and right-hand stabilize) with the order of the sessions counterbalanced between groups. Our results indicate a hand by task-component interaction such that the right hand showed straighter reaching performance whereas the left hand showed more stable holding performance. These findings provide support for the complementary dominance hypothesis and suggest that the specializations of each cerebral hemisphere for impedance and dynamic control mechanisms are expressed during bilateral interactive tasks. NEW & NOTEWORTHY We provide evidence for interlimb differences in bilateral coordination of reaching and stabilizing functions, demonstrating an advantage for the dominant and nondominant arms for distinct features of control. These results provide the first evidence for complementary specializations of each limb-hemisphere system for different aspects of control within the context of a complementary bilateral task.

Rediscovering Leon Theremin

Tempo ◽  
1991 ◽  
pp. 18-23 ◽  
Author(s):  
Stephen Montague
Keyword(s):  
Electromagnetic Field ◽  
The Other ◽  
Electronic Instrument ◽  
Left Hand ◽  
Vertical Antenna ◽  
Right Hand ◽  
Concert Halls ◽  
The Right

In the early 1920s and 30s a strange electronic instrument found its way from Russia into some of the more fashionable ballrooms, night clubs, and concert halls in Europe and America. This exotic new invention, called the ‘theremin’ or ‘thereminvox’, caused a considerable stir. Part of the interest was its unusual sound (like a musical saw mated with a light soprano), but its most dramatic feature was that the performer never actually touched the instrument. He or she simply waved graceful hands near the two antennae (one set vertically, the other looped horizontally) to coax out seamless, melifluous melodies. The proximity of the right hand to the vertical antenna changed the ultrasonic electromagnetic field, thus changing the pitch over about a six-octave range. The left hand (or sometimes a foot pedal) controlled the volume. By gently shaking the right hand at the antenna a vibrato could be achieved, giving performances a little more musical (not to mention choreographic) interest. Fashionable women dressed in long gowns seemed to be favourite photographic subjects of the period as performers, as well as the inventor himself, poised ‘playing the rods’ in full dress tails, arms outstretched like a great conductor–or perhaps sorcerer.

scholarly journals XIV.—Ancient Gold Ornaments: described by John Yonge Akerman, Esq. Secretary

Archaeologia ◽  
1853 ◽  
Vol 35 (1) ◽  
pp. 190-193
Author(s):  
John Yonge Akerman
Keyword(s):  
Light Chain ◽  
The Body ◽  
The Other ◽  
Asia Minor ◽  
Plate Viii ◽  
Left Hand ◽  
Small Loop ◽  
The Individual ◽  
The Right ◽  
Of Greece

With the exception of Figs. 1, 2, 3, the Gold Ornaments engraved in Plate VIII. have no reference whatever to each other. The first three were obtained by Viscount Strangford, Director of the Society, from a Greek priest at Milo, in the year 1820. Figs. 1 and 3 appear to have formed the ends of a light chain, and the other (fig. 2) to have been pendent by a small loop on the top of the head. The figure has unfortunately lost the feet and the left hand, but the other parts are perfect. The right hand is raised in an admonitory attitude. The forehead appears as if encircled with a wreath, while the body is crossed by what would seem to be intended for the tendril of a vine. The necklace was formerly in the collection of the late Mr. H. P. Borrell, of Smyrna, but I am informed by his brother, Mr. Maximilian Borrell, who now possesses it, that no record exists of its discovery, and that he cannot learn the name of the individual from whom it was purchased. It was well known that Mr. H. P. Borrell was in the habit of purchasing ancient coins, which were sent to him from all parts of Greece and Asia-Minor, and that many rare and unique specimens fell into his hands, of which he contributed descriptions in various volumes of the Numismatic Chronicle. The necklace may, therefore, have been included in one of these numerous consignments, and we can scarcely indulge the hope that the place of its discovery will ever be made known. As an example of ancient art, it may vie with the most elaborate and beautiful specimens of goldsmiths' work of any age or period. The details are wonderfully minute and delicate, even the backs of the button-like objects at the ends of the pendent cords being elaborately finished.

Failure to Sing the Left-Hand Part of the Score during Piano Performance: Loss of the Pitch and Stroop Vocalizations

1989 ◽  
Vol 6 (3) ◽  
pp. 299-314 ◽  
Author(s):  
Yves Guiard
Keyword(s):  
The Other ◽  
Vocal Response ◽  
Left Hand ◽  
Performance Loss ◽  
Clear Cut ◽  
Right Hand ◽  
Hand Part ◽  
Continuous Regime ◽  
And Performance ◽  
The Right

An experiment compared the ability of classical pianists to sing, during keyboard performance, the right- and the left-hand part of the score being played. Upon instructions requiring them to "sing" one or the other voice of the score, the subjects spontaneously chose to sing and name the notes simultaneously, in keeping with the French traditional way of reading music, thus producing a two- dimensional tonal and verbal vocal act in response to each visual stimulus. Singing the right-hand part of the music, whether in unison with or in place of the right hand, while concurrently playing the left-hand part was judged easy by all subjects, and performance, typically, was correct in all respects. The other task, consisting of singing the left-hand part of the music, was judged more difficult by all subjects, and performance, more often than not, was poor. Careful inspection of the many errors that were recorded in the latter task revealed a few clear-cut regularities. Failures were vocal, but not manual. More specifically, vocal failures took place on the tonal dimension of the vocal response, but not on its verbal dimension: The song, but not the naming of the notes, was prone to fail, with either a loss of the pitch, or a systematic trend toward singing unduly—albeit accurately—the notes of the right-hand part. A number of subjects were found to display this intriguing tonal/verbal dissociation—naming a note at a pitch corresponding to another note—in a continuous regime. It is emphasized that this phenomenon amounts to the spontaneous production of musical events that belong to the Stroop category.

On a New Type of Vibrating Lift

1980 ◽  
Vol 102 (2) ◽  
pp. 264-269
Author(s):  
J. Inoue ◽  
Y. Araki ◽  
S. Kubo
Keyword(s):  
The Self ◽  
The Other ◽  
Vertical Position ◽  
Horizontal Position ◽  
Linear Vibration ◽  
Left Hand ◽  
Asynchronous Motors ◽  
Rotational Vibration ◽  
New Type ◽  
The Right

This paper investigates in detail the new vibrating lift made by utilizing the principle of the self-synchronization of mechanical vibrators. In a general way products ride up inclined way of the spiral trough of a vibrating lift, propelled by forces generated by two unbalanced rotors connected by the gear and driven by a motor, which are mounted on top of the structure in a horizontal position. This machine is a new type of vibrating lift. The axes of two unbalanced rotors are nonparallel and each driven by two asynchronous motors. One motor is positioned on the right hand side and the other is situated on the left hand side of the structure in a vertical position. In spite of the absence of any connection between two rotors, they rotate at the same speed and have the definite phase angle between them as the result of the phenomena of the self-synchronization under a certain condition. This phenomenon is also called entrainment. Accordingly, by the linear vibration in the direction of the axis of the structure and rotational vibration about the axis of the structure by two unbalanced rotors, products ride up inclined way of the spiral trough.

scholarly journals Synchronization Error of Drum Kit Playing with a Metronome at Different Tempi by Professional Drummers

2011 ◽  
Vol 28 (5) ◽  
pp. 491-503 ◽  
Author(s):  
Shinya Fujii ◽  
Masaya Hirashima ◽  
Kazutoshi Kudo ◽  
Tatsuyuki Ohtsuki ◽  
Yoshihiko Nakamura ◽  
...  
Keyword(s):  
Time Series ◽  
The Other ◽  
Synchronization Error ◽  
Left Hand ◽  
Snare Drum ◽  
Right Hand ◽  
The Absolute ◽  
The Right

the present study examined the synchronization error (SE) of drum kit playing by professional drummers with an auditory metronome, focusing on the effects of motor effectors and tempi. Fifteen professional drummers attempted to synchronize a basic drumming pattern with a metronome as precisely as possible at tempi of 60, 120, and 200 beats per minute (bpm). In the 60 and 120 bpm conditions, the right hand (high-hat cymbals) showed small mean SE (∼2 ms), whereas the left hand (snare drum) and right foot (bass drum) preceded the metronome by about 10 ms. In the 200 bpm condition, the right hand was delayed by about 10 ms relative to the metronome, whereas the left hand and right foot showed small SE (∼1 ms). The absolute values of SE were smaller than those reported in previous tapping studies. In addition, the time series of SE were significantly correlated across the motor effectors, suggesting that each limb synchronized in relation to the other limbs rather than independently with the metronome.

Greek Vases in the Otago Museum

1936 ◽  
Vol 56 (2) ◽  
pp. 235-236
Author(s):  
A. D. Trendall
Keyword(s):  
New Zealand ◽  
Fifth Century ◽  
The Other ◽  
Left Hand ◽  
Right Hand ◽  
Greek Vases ◽  
The Right

Of the recent acquisitions to the Classical Collection of the Otago Museum (Dunedin, New Zealand) the most noteworthy is a particularly fine Attic white ground lekythos of about the middle of the fifth century (Plate XIV). It stands 38 cm. high and is in an excellent state of preservation, having been most carefully repaired with a minimum of repainting, which has affected only the breast of the woman, the right hand of the warrior, and some details of the small figure on top of the stele.The design represents a stele scene of the sort so popular with lekythos artists of this period. To the left stands a woman wearing a sleeved chiton, so thin that it clearly allows her bowed legs to be seen through it; with her left hand she points downward to the base of the stele, which is adorned with a fillet and a wreath. On the other side stands a hoplite with his shield and spear;

The Growth of Sparta

1913 ◽  
Vol 33 ◽  
pp. 246-275 ◽  
Author(s):  
Arnold J. Toynbee
Keyword(s):  
Acute Angle ◽  
The Other ◽  
Left Hand ◽  
Narrow Ridge ◽  
The Right

If you walk out of modern Sparta by the Tripolis road, and take the first branch road to the right after crossing Eurotas, you find yourself moving parallel to the river, with a line of red bluffs on your left hand. The bluffs grow higher and steeper as you go south, and the river edges closer to their foot, till opposite the junction of the Magoula river there is barely room for the cart-track between hillside and Eurotas-bed: but here the line of the bluffs is suddenly broken by a dry ravine converging on the course of the Eurotas at an acute angle from the N.E. The flanks of this ravine are at first as steep as the western face of the bluffs: but after about ten minutes' walk up it, several bays open on the left, affording an ascent to the bluff's summit by an easier gradient. When you reach the top you find yourself on a narrow ridge crowned by a chapel of the prophet Elias, and clearly marked off from the other summits to N. and S. Just N. of the chapel is the shrine of Menelaos, where the citizens of ‘historical’ Sparta used to offer lead figurines. But under the ‘historical’ stratum are the vestiges of a ‘Mycenaean’ city.

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