Bone changes after maxillary sinus surgery: an experimental scanning electron microscopy study

2007 ◽  
Vol 122 (5) ◽  
pp. 470-475 ◽  
Author(s):  
P M Moreno ◽  
D H Meseguer

AbstractAims:The purpose of this study was to explore the pathogenic role of bone in sinus surgery, and to determine whether mucosal disease after sinus surgery may be induced by underlying disease within the bone.Material and methods:Twenty-five rabbits were divided into five groups. In group one, wide surgical removal of the maxillary sinus mucosa and creation of a nasoantral window were undertaken. In group two, only nasoantral window creation was undertaken. In group three, the mucosa of the anterior maxillary sinus was removed. In group four, a strip of mucosa around the ostium was removed. Group five was used as a control.Results:After three months, in the groups which had undergone wide surgical removal, the medial sinus walls were observed to be retracted and the inner curtain of the bone disturbed, with alteration of the haversian canal system and osteoclastic bone resorption.Conclusions:After radical sinus surgery, electron microscopic changes were observed in the bony walls, similar to those changes seen in osteomyelitis.

Author(s):  
A. Lupulescu ◽  
J.E. Habowsky ◽  
J. Milkintas ◽  
D. Birmingham

Recent light and electron microscopic studies showed that corticosteroids and testosterone induced changes in the structure of fibroblasts and collagen synthesis. Our previous investigations demonstrate that also calcitonin significantly interferes with collagen synthesis and fibroblast growth in wounded rabbits.Conflicting findings were reported by using biochemical and light microscopic studies following estrogens and thyroxine administration. This report concerns some investigations with regard to the role of estradiol and thyroxine on collagen synthesis in rats.Adult male rats were used in these experiments. They were divided in three groups of 10 rats each. A) Thyroxine-treated rats: each rat received intramuscularly (im) 100 μg thyroxine (Synthroid), every other day, for one month. B) Estrogen-treated rats: each rat received 500 μg estradiol dipropionate, every other day, for one month. C) Controls, received only the diluent.


Author(s):  
Gustav Ofosu

Platinum-thymine has been found to be a potent antitumor agent, which is quite soluble in water, and lack nephrotoxicity as the dose-limiting factor. The drug has been shown to interact with DNA and inhibits DNA, RNA and protein synthesis in mammalian cells in vitro. This investigation was undertaken to elucidate the cytotoxic effects of piatinum-thymine on sarcoma-180 cells in vitro ultrastructurally, Sarcoma-180 tumor bearing mice were treated with intraperitoneal injection of platinum-thymine 40mg/kg. A concentration of 60μg/ml dose of platinum-thymine was used in in vitro experiments. Treatments were at varying time intervals of 3, 7 and 21 days for in vivo experiments, and 30, 60 and 120 min., 6, 12, and 24th in vitro. Controls were not treated with platinum-thymine.Electron microscopic analyses of the treated cells in vivo and in vitro showed drastic cytotoxic effect.


1993 ◽  
Vol 311 ◽  
Author(s):  
D.D. Medlin ◽  
T.T. Friedmann ◽  
P.P. Mirkarimi ◽  
K.K. Mccarty ◽  
M.M. Mills

ABSTRACTWe present a microstructural study of boron nitride films grown by ion-assisted pulsed laser deposition. Fourier transform infra-red spectroscopy, electron energy loss spectroscopy, and electron diffraction measurements indicate that within the irradiated region of the substrate, the film consists of high fraction of cBN with a small amount of the turbostratic phase; outside of the irradiated region, only the turbostratic phase is detected. Conventional and high resolution electron microscopic observations of the boron nitride microstructure indicate that the cBN is in the form of twinned crystallites, up to 30 nm in diameter. We also observe particulates, formed by the laser pulse, that reduce the yield of cBN in the irradiated regions by shadowing local areas from the ion beam.


2015 ◽  
Vol 10 (3) ◽  
pp. e993264
Author(s):  
Archana Singh ◽  
Mohammad Wahid Ansari ◽  
C P Singh ◽  
Alok Shukla ◽  
Ramesh Chandra Pant ◽  
...  

2010 ◽  
Vol 16 (S2) ◽  
pp. 1270-1271
Author(s):  
H Yoshida ◽  
T Shimizu ◽  
T Uchiyama ◽  
H Kohno ◽  
S Takeda

Extended abstract of a paper presented at Microscopy and Microanalysis 2010 in Portland, Oregon, USA, August 1 – August 5, 2010.


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