Nasal craniopharyngioma: case report and literature review

2011 ◽  
Vol 125 (5) ◽  
pp. 517-519 ◽  
Author(s):  
J C Magill ◽  
M S Ferguson ◽  
A Sandison ◽  
P M Clarke
Keyword(s):  
Case Report ◽  
Adjuvant Radiotherapy ◽  
English Language ◽  
Middle Turbinate ◽  
Craniofacial Resection ◽  
Complete Excision ◽  
First Case ◽  
History Of ◽  
One Year ◽  
Midfacial Degloving

AbstractObjective:We report the first case in the English language literature of an adamantinomatous infrasellar craniopharyngioma, and we describe our management strategy.Case report:A 46-year-old woman presented with a six-month history of left-sided nasal obstruction and epistaxis. Rhinological examination revealed a left-sided, polypoidal lesion lying medial to the middle turbinate. An urgent examination under anaesthesia was organised; biopsies were considered characteristic of craniopharyngioma. Magnetic resonance imaging and computed tomography demonstrated a well defined, heterogeneous, infrasellar mass centred in the midline, extending anteriorly into the left nasal cavity and posteriorly encasing both internal carotid arteries. Craniofacial resection was performed via a midfacial degloving approach, with adjuvant radiotherapy. The patient was disease-free one year post-operatively.Conclusion:Craniopharyngiomas should be considered in the differential diagnosis of a unilateral nasal polyp. Although technically benign, they are locally aggressive. Therefore, we recommend complete excision with adjuvant radiotherapy if margins are involved or close.

Inflammatory myofibroblastic tumour of the tonsil: case report and literature review

2010 ◽  
Vol 124 (10) ◽  
pp. 1123-1125 ◽  
Author(s):  
J C Magill ◽  
M S Ferguson ◽  
C R Butler ◽  
A Sandison ◽  
W E Grant
Keyword(s):  
Case Report ◽  
Pregnant Woman ◽  
English Language ◽  
Spindle Cell Carcinoma ◽  
Inflammatory Myofibroblastic Tumour ◽  
Complete Excision ◽  
Recommended Treatment ◽  
History Of ◽  
High Grade Carcinoma ◽  
The Right

AbstractObjective:We present the first reported case in the English language literature of an inflammatory myofibroblastic tumour of the right tonsil in a young, pregnant woman, and we report a management strategy for this enigmatic entity.Case report:A 28-year-old, pregnant woman presented with a 10-day history of odynophagia despite a course of antibiotics. Examination revealed a grade II, erythematous right tonsil with ulceration on the upper pole. A biopsy was arranged, and initial evaluation was suggestive of spindle cell carcinoma. However, this diagnosis was reviewed after immunohistochemical staining confirmed an inflammatory myofibroblastic tumour. Subsequent complete excision was undertaken using CO2laser.Conclusion:Clinically, inflammatory myofibroblastic tumour of the tonsil is known to be locally aggressive and can present in a manner not dissimilar to a high grade carcinoma of the tonsil. As a result, the recommended treatment is complete local excision with careful follow up.

scholarly journals  Erythema multiforme minor in a dog following inappropriate intranasal Bordetella bronchiseptica vaccination: a case report

2011 ◽  
Vol 56 (No. 11) ◽  
pp. 568-572 ◽  
Author(s):  
MH Kang ◽  
HM Park
Keyword(s):  
Case Report ◽  
Erythema Multiforme ◽  
Clinical Signs ◽  
Skin Lesions ◽  
Bordetella Bronchiseptica ◽  
Hydropic Degeneration ◽  
First Case ◽  
History Of ◽  
One Year

A one-year-old, intact female, Yorkshire terrier dog was presented with a six-month history of multifocal, polycyclic erythematous lesions with epidermal collarette formation at the axillae, the trunk and ventral abdomen. The dog had a history of an inappropriate vaccine administration one day prior to the onset of clinical signs. The histopathology of the lesions revealed apoptosis of keratinocytes in the overlying epidermis, hydropic degeneration and lymphocytic exocytosis. The clinical signs and histopathology of the lesions were compatible with erythema multiforme. The skin lesions resolved after treatment with prednisolone combined with azathioprine for one month. No recurrence of clinical signs occurred during the follow-up period (four months). This is the first case report of erythema multiforme associated with an accidental subcutaneous injection of a Bordetella bronchiseptica vaccine.  

scholarly journals Post Traumatic Chronic Encapsulated Intracerebral Hematoma in a Child: Case Report and Brief Review of Literature

2017 ◽  
Vol 14 (3) ◽  
pp. 46-48
Author(s):  
Yam Bahadur Roka ◽  
Mohan Karki
Keyword(s):  
Case Report ◽  
Clinical Symptoms ◽  
Neurological Deficits ◽  
Intracerebral Hematoma ◽  
Diagnostic Modality ◽  
Ct Guided ◽  
Stereotactic Aspiration ◽  
First Case ◽  
History Of ◽  
One Year

Chronic encapsulated intracerebral hematoma (CE-ICH) is an uncommon pathology that presents with headache, seizure, focal neurological deficits, or as a tumor. Trauma as a cause for CE-ICH is even rare and we believe this is the first case report as “trauma causing chronic encapsulated intracerebral hematoma “search in PubMed did not reveal any results. Repeated micro-hemorrhages in the CM or AVM are supposed to cause this lesion which progress from an earlier encapsulated phase to a thick capsulated stage with edema and clinical symptoms. CT or MRI is the diagnostic modality and it mimics, tumor, AVM, CM, angiomableed, cerebral abscess, metastatic mass or neurocysticercosis. Burr hole, mini-craniotomy, craniotomy, CT guided stereotactic aspiration or endoscopic excision are some options with equally good results. The present case with history of trauma was managed successfully with craniotomy with no recurrence for past one year. Nepal Journal of Neuroscience, Volume 14, Number 3, 2017, page: 46-48

scholarly journals A Suspected Metastatic Liposarcoma of the Inferior Alveolar Nerve Canal: A Case Report and Literature Review

2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Sara Pourshahidi ◽  
Marzieh Yousefian ◽  
Soheila Manifar ◽  
Farzaneh Mosavat ◽  
Mohsen Esfandbod ◽  
...  
Keyword(s):  
Case Report ◽  
Head And Neck ◽  
English Language ◽  
Inferior Alveolar Nerve ◽  
Suspected Case ◽  
Lower Lip ◽  
Case Presentation ◽  
First Case ◽  
History Of ◽  
Inferior Alveolar Nerve Canal

Introduction: Liposarcoma is the most common soft tissue sarcoma, but it is relatively scarce in the head and neck. The metastatic liposarcoma is more infrequent than the primary one. Case Presentation: Here is presented a suspected case of metastatic liposarcoma in the inferior alveolar nerve canal in a 40-year-old female patient with a chief complaint of the chin and lower lip numbness and medical history of liposarcoma in the thigh. The present study was a case report for metastatic liposarcoma in the head and neck regions, according to the English language literature found in PubMed and Google Scholar. The search was performed using the keywords "Metastatic Liposarcoma" and "Head" and "Neck". Conclusions: According to the findings, the reported case may be the first case of the metastasis of liposarcoma in the inferior alveolar nerve canal. Ominous signs, such as numbness, should be considered in patients with a history of cancer, due to their warning for metastasis or recurrence of the tumor.

scholarly journals Intraparenchymal Supratentorial Neurenteric Cyst

2004 ◽  
Vol 31 (3) ◽  
pp. 412-416 ◽  
Author(s):  
Edward Kachur ◽  
Lee-Cyn Ang ◽  
Joseph F. Megyesi
Keyword(s):  
Cystic Lesion ◽  
Brain Parenchyma ◽  
Neurenteric Cyst ◽  
Complete Excision ◽  
First Case ◽  
History Of ◽  
The Central Nervous System ◽  
One Year ◽  
The Right ◽  
The Brain

Background:Neurenteric cysts are congenital cysts of the central nervous system that are believed to be of endodermal origin. In this report we present the unique case of a supratentorial neurenteric cyst that is contained entirely within the brain parenchyma.Methods:Apatient presented with an intraparenchymal cystic lesion that was subsequently identified as a neurenteric cyst. This lesion is reviewed in light of the available literature.Case report:A 35-year-old female presented with a one year history of progressive headaches and seizure-like episodes. Her examination revealed no deficits. Magnetic resonance imaging showed a 4 cm x 4 cm x 4 cm cystic lesion within the parenchyma of the right frontal lobe. A right frontal craniotomy and complete excision of the cystic lesion was performed. Pathologic examination confirmed that it was a neurenteric cyst. Postoperatively the patient's symptoms improved.Conclusion:Review of the literature revealed this to be the first case of a surgically excised, pathologically confirmed supratentorial neurenteric cyst, contained entirely within the brain parenchyma.

Case Report: Management of a Patient with mTBI and Vestibular Hypofunction with the Binasal Occlusion Technique

2018 ◽  
pp. 87-90
Keyword(s):  
Case Report ◽  
Visual Motion ◽  
Hand Movement ◽  
Motion Sensitivity ◽  
Vestibular Hypofunction ◽  
First Case ◽  
Neurological Exam ◽  
History Of ◽  
Occlusion Technique ◽  
Visual Vertigo

Background: Binasal Occlusion (BNO) is a clinical technique used by many neurorehabilitative optometrists in patients with mild traumatic brain injury (mTBI) and increased visual motion sensitivity (VMS) or visual vertigo. BNO is a technique in which partial occluders are added to the spectacle lenses to suppress the abnormal peripheral visual motion information. This technique helps in reducing VMS symptoms (i.e., nausea, dizziness, balance difficulty, visual confusion). Case Report: A 44-year-old AA female presented for a routine eye exam with a history of mTBI approximately 33 years ago. She was suffering from severe dizziness for the last two years that was adversely impacting her ADLs. The dizziness occurred in all body positions and all environments throughout the day. She was diagnosed with vestibular hypofunction and had undergone vestibular therapy but reported little improvement. Neurological exam revealed dizziness with both OKN drum and hand movement, especially in the left visual field. BNO technique resulted in immediate relief of her dizziness symptoms. Conclusion: To our knowledge, this is the first case that illustrates how the BNO technique in isolation can be beneficial for patients with mTBI and vestibular hypofunction. It demonstrates the success that BNO has in filtering abnormal peripheral visual motion in these patients.

CONGENITAL MICROGASTRIA, A CASE REPORT WITH A 26-YEAR FOLLOW-UP

PEDIATRICS ◽  
1973 ◽  
Vol 51 (6) ◽  
pp. 1037-1041
Author(s):  
Eugene Blank ◽  
Alvin Chisolm
Keyword(s):  
Case Report ◽  
English Language ◽  
Normal Adult ◽  
Healthy Children ◽  
Adult Size ◽  
Persistent Vomiting ◽  
First Case ◽  
English Language Journal ◽  
Roentgenographic Examination

A 27-year-old woman had congenital microgastria, which was apparent in roentgenographic examination when she was 1 year of age. Despite inability to eat anything but pureed foods for the first 13 years and despite persistent vomiting during that time, she has reached normal adult size and has three healthy children. This report represents two firsts: the first case of congenital microgastria in an English language journal of pediatrics and the first with a long follow-up.

scholarly journals Rhino-orbital COVID-19 associated mucormycosis- A case report

2021 ◽  
Vol 7 (4) ◽  
pp. 304-307
Author(s):  
Shanmuga Vadivoo Natarajan ◽  
B Usha
Keyword(s):  
Diabetes Mellitus ◽  
Infectious Disease ◽  
Case Report ◽  
Tertiary Care ◽  
Notifiable Disease ◽  
Health Ministry ◽  
First Case ◽  
Uncontrolled Diabetes ◽  
History Of ◽  
Second Wave

COVID-19 Associated Mucormycosis (CAM) is an emerging infectious disease that has caused increased mortality & morbidity in India during this second wave of the pandemic. The country has reported more than 30,000 cases and over 2,000 deaths by Mucormycosis so far, according to sources from Union Health Ministry. CAM is now a notifiable disease. At our Tertiary care teaching hospital, which caters for COVID 19 management, we are reporting the first case of Rhino orbital CAM, which was caused by Rhizopus spp. Our patient had a history of contact with a suspected COVID 19 patient and was recently diagnosed with uncontrolled diabetes mellitus. A direct KOH microscopic examination of purulent material aspirated from the sinonasal polyp of the patient revealed fungal elements, and Rhizopus spp was isolated. Due to a shortage of Amphotericin B, the patient was referred to a government higher speciality centre for further management. The patient was followed up & was noted that he was treated with antifungal and discharged following recovery.

scholarly journals Adrenal Ganglioneuroma with Multifocal Retroperitoneal Extension: A Challenging Diagnosis

2011 ◽  
Vol 11 ◽  
pp. 1548-1553 ◽  
Author(s):  
Marco Oderda ◽  
Elena Cattaneo ◽  
Francesco Soria ◽  
Antonella Barreca ◽  
Luigi Chiusa ◽  
...  
Keyword(s):  
Case Report ◽  
Nervous Tissue ◽  
Rare Case ◽  
Histological Evaluation ◽  
Adrenal Incidentalomas ◽  
Complete Excision ◽  
First Case ◽  
Neuroblastic Tumors ◽  
Sympathetic Nervous ◽  
Adrenal Ganglioneuroma

A ganglioneuroma (GN) is the rarest and most benign of the neuroblastic tumors and originates from neural crest cells wherever sympathetic nervous tissue exists, such as in the retroperitoneum and adrenal gland. The diagnosis can be very challenging, given the rarity and asymptomatic presentation of this neoplasia, and can be achieved only by means of histological evaluation. Although benign, a few cases of metastatic GNs have been reported in the literature. The prognosis, however, seems to be excellent after surgical resection. We describe a rare case of multifocal retroperitoneal GN, diagnosed incidentally in a 46-year-old woman, with para-aortic and adrenal localizations. After intraoperative pathological diagnosis was made, complete excision of all the visible masses was performed. The postoperative period was uneventful and she was recurrence free 3 months after surgery. To our knowledge, this is the first case report of a multifocal retroperitoneal GN. Among the broad differential diagnoses of adrenal incidentalomas, an adrenal location of neuroblastic tumors should not be forgotten.

scholarly journals Metastatic Pancreatic Cancer with BRAF and P53 Mutations: Case Report of Therapeutic Response to Doublet Targeted Therapy

2020 ◽  
Vol 13 (3) ◽  
pp. 1239-1243
Author(s):  
Shenthol Sasankan ◽  
Lorraine Rebuck ◽  
Gloria Darrah ◽  
Moises Harari Turquie ◽  
Ian Rabinowitz
Keyword(s):  
Pancreatic Cancer ◽  
Case Report ◽  
Targeted Therapy ◽  
Therapeutic Response ◽  
Case Reports ◽  
Clinical History ◽  
P53 Mutation ◽  
Metastatic Pancreatic Cancer ◽  
First Case ◽  
History Of

We report on the clinical history of a 49-year-old female with metastatic pancreatic cancer. She was initially treated with standard chemotherapy as per current guidelines. She was found to have both a BRAF and P53 mutation, and received dabrafenib and trametinib with deep responses, both radiographically and biochemically (CA19-9). Her response has been more clinically relevant than responses in previous case reports of patients with BRAF-positive pancreatic cancer treated with targeted therapy. To the best of our knowledge, this is the first case report showing a dramatic therapeutic response to combination therapy with dabrafenib and trametinib in metastatic pancreatic cancer.

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