Genetic influences on eating attitudes in a normal female twin population

1993 ◽  
Vol 23 (2) ◽  
pp. 425-436 ◽  
Author(s):  
J. Rutherford ◽  
P. McGuffin ◽  
R. J. Katz ◽  
R. M. Murray

SynopsisThe Eating Attitudes Test (EAT) and the Eating Disorder Inventory (EDI) were administered to a female volunteer twin population aged 18 to 45 years. Both members of 147 monozygotic (MZ) and 99 dizygotic (DZ) twin pairs completed the questionnaires. Thirty-five subjects scored over the cut-off point of the EAT-26. Interviews of these high-scoring twins and their co-twins identified three subjects with a past history of anorexia nervosa, and three others with a history of a partial syndrome. A heritability value of 41% was obtained for the overall EAT scores, while factor analysis produced a ‘dieting’ factor with a heritability of 42%. The ‘body dissatisfaction’ and ‘drive for thinness’ subscales of the EDI had heritability values of 52 and 44% respectively. The genetic contribution to the variance in body mass index in the twin sample was estimated at 64%. For all the above phenotypes, an environmental model of transmission with heritability constrained to be zero, could be rejected. Conversely, we were unable to reject a purely additive genetic model with shared environmental variance constrained at zero, suggesting that family environment has little or no effect on the transmission of many of these traits.

1995 ◽  
Vol 25 (5) ◽  
pp. 1019-1025 ◽  
Author(s):  
I. F. Dancyger ◽  
P. E. Garfinkel

SYNOPSISA variety of sociocultural, familial and individual features associated with the eating disorders were examined in subjects with full syndrome (FS) and partial syndrome (PS) eating disorders and in normal high school students. The EAT-26 was administered to 995 high school students. This was followed by individual interviews with those who scored in the symptomatic range. Fifty-one students with PS eating disorders, 57 students without eating disorders (normal controls) and 30 hospital patients with FS, anorexia nervosa or bulimia nervosa were compared on subscales of the Eating Disorder Inventory, the Diagnostic Survey for Eating Disorders and the Beck Depression Inventory. The three groups displayed statistically significant differences on dimensions of EDI subscales Ineffectiveness and Interoceptive Awareness and also with respect to depression, history of being overweight and past history of emotional problems, as well as having mothers with medical illnesses. On these characteristics, the FS subjects displayed higher levels than the PS subjects, who in turn were higher than the NC subjects. The PS subjects displayed elevations on Body Dissatisfaction (EDI subscale), past medical illnesses, and mother's over-concern with eating and weight. These data support a continuum model of the eating disorders, but a continuum of multiple associated features rather than of dieting.


2019 ◽  
Vol 4 ◽  
pp. 2
Author(s):  
Shubhashree Venkatesh ◽  
Anita Nath ◽  
Sheeba Balan ◽  
Vindhya J ◽  
Chandra S. Metgud ◽  
...  

Background: Worldwide, the occurrence of obesity has markedly increased over the past decades with serious public health consequences. Obese pregnant women are more likely to develop hypertension, pre-eclampsia and gestational diabetes, resulting in obstetric complications which in turn may contribute to an increase in adverse child outcomes and maternal mortality. The present study was done to determine the prevalence of obesity and its association with socio-demographic variables, obstetric history and mental health. Methods: This study was nested within an ongoing cohort study, CASCADE, in a public hospital in Bangalore. The study participants comprised of 280 pregnant women who were 18 years of age and above, with a gestational age of less than 24 weeks, enrolled between a period of August 1st, 2017 until April 30th, 2018. Weight and height were measured using calibrated devices to calculate the body mass index. Results: The prevalence of obesity was observed to be 33.9% among the pregnant mothers. Obesity was found to be significantly associated with age, history of abortion, gravidity on multivariate logistic regression. No association was found with depression and anxiety. Conclusions: Obesity is an important health concern among urban pregnant women in the region of South India. The prevalence is much higher than that reported in other studies. Increasing age, multigravidity and past history of abortion were significantly associated with maternal obesity.


Author(s):  
Sandipan Barkakaty ◽  
Girish K.

Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are severe idiosyncratic reactions characterized by fever and mucocutaneous lesions leading to necrosis and sloughing of the epidermis. The usage of anticonvulsants like carbamazepine, phenytoin, lamotrigine, phenobarbital are associated with high risk for occurrence of TEN. We present a case of toxic epidermal necrolysis in a 30 year old female probably induced by phenytoin. A 30 year old female was admitted to the emergency medicine department of KIMS hospital, Bengaluru. Lesions over the lips and oral cavity, multiple fluid filled blisters were present diffusely all over the body. Patient had a past history of oral cavity lesions with injection phenytoin. Patient is a known epileptic of over 12 years and was on treatment. Patient had a seizure attack 3 days back and visited nearby hospital and did not inform the doctor of her allergy to phenytoin. Patient was given inj phenytoin after which she developed oral lesions and also presented with fluid filled bullae all over the body. A diagnosis of toxic epidermal necrolysis was made based on clinical history and Scoreten score and was treated with betadine wash, fluconazole and antibiotics .The lesions improved significantly with the above management and patient recovered enough to be discharged from the hospital after 5 days. Severe and serious reactions such as toxic epidermal necrolysis can be caused by commonly used drugs like phenytoin.


2021 ◽  
Vol 7 (3) ◽  
pp. 21
Author(s):  
Pınar Tatlıbal

Body dissatisfaction and disordered eating behavior in athletes may occur when sports and social pressures require an ideal body standard, if the athlete perceives that his or her body does not conform to this ideal. For this reason, the aim of this study is to investigate the relationship between artistic gymnasts’ (AG) physical profiles, body appreciation levels and eating attitudes. A total of 32 elite AG (Turkish National Team), 13 women and 19 men, participated in this study. Height and body analyzes of the participants were measured. Body appreciation levels were determined by the Body Appreciation Scale (BAS), and eating attitudes were determined by the Eating Attitudes Test (EAT-26). With the Training Information Form, information about training frequencies and durations was provided. Comparative analyzes of the BAS and EAT-26 results of elite female and male gymnasts were performed. The physical profiles, eating attitudes and body appreciation levels of female AG were evaluated and the relationship between them was determined. While no significant correlation was found between the BAS, EAT-26 and physical profiles of the elite male AG, a negative significant correlation was found between the BAS and body mass index (BMI) of female elite AG (p < 0.05). It was concluded that while BMI rates of elite female AG increased, their body appreciation levels decreased. The BAS results of elite AG’ were found to be significantly higher than those of elite female AGs (p < 0.05).


2021 ◽  
Vol 11 (6) ◽  
Author(s):  
Gabriel Pina ◽  
David Pereira ◽  
Nuno Borralho ◽  
Manuel Sousa

Introduction: Gossypiboma or textiloma is the technical term used to describe a surgical complication related to accidental retention of surgical material within the body, most often surgical swabs. Since it is rare in orthopedic surgery, its diagnostis is less common and often initially mistaken with soft-tissue tumors. The aim of this study is to point out the importance of this differential diagnosis in the event of clinical swelling or accidental intraoperative finding associated with previous surgery. Case Report: Female patient presenting with 3 weeks hip pain and inflammatory signs, with a past history of a total hip arthroplasty 15 years before. Analytically presented C-reactive protein CRP of 13.67 mg/dl. Ultrasound and computed tomography CT scan revealed a solid lesion in the anterior thigh root and a liquid lesion in the lateral region of the hip. Discussion: Gossypibomas can be classified into two types: The aseptic fibrous type, which produces adhesions and a fibrotic capsule, and the exudative type, which is characterized by abscess formation. This case report refers to an aseptic fibrous type, given an asymptomatic evolution over 15 years and histopathological findings. However, this diagnosis occurred following a periprosthetic hip infection. Keywords: Gossypiboma, muslinoma, textiloma, total hip arthroplasty. Gossypiboma, Textiloma, Muslinoma, Total hip arthroplasty


2018 ◽  
Vol 4 (1) ◽  
pp. 43
Author(s):  
Armando Afonso Jr ◽  
Thales Ferro ◽  
Luis Anunciação ◽  
J. Landeira-Fernandez

The discrepancy between one’s actual body and the ideal body, especially among young adults, can lead to body dissatisfaction in both men and women, which is commonly accepted to be central to eating disorders. We explored aspects of body image and eating disorders in healthy Brazilian students (n = 219) using two standardized measures (Body Shape Questionnaire [BSQ-34] and Eating Attitudes Test [EAT-26]) and assessing height, weight, Body Mass Index (BMI), and the history of physical activity. We also analyzed the ability of one measure to predict another. Linear multiple regression was used to verify which variables best predicted the scale outcomes. The Least Absolute Shrinkage and Selection Operator (LASSO) was used for variable selection. The results suggested that women have a greater risk of body dissatisfaction and eating disorders. Both instruments had variables that significantly predicted each other’s results, whereas BMI was only associated with BSQ-34 scores. These findings broaden our understanding of eating disorders and body image.


2021 ◽  
Vol 9 ◽  
pp. 2050313X2110537
Author(s):  
Yingying Xu ◽  
Zongkui Duan ◽  
Wenqing Hu ◽  
Kaixuan Zhu ◽  
Peng Cui ◽  
...  

Melanomas most commonly localized in the skin can arise anywhere in the body, and approximately 5% of all melanomas appear in other sites of mucosal surfaces out of skin. Primary melanoma from nasal mucosa is quite rare. We present this case: a 46-year-old man had complained a pain in the left upper abdomen for 2 months when he was admitted to the Northern Jiangsu People’s Hospital. The pain was paroxysmal and enhanced when eating. There was no nausea, vomiting, or anorexia. There had been no change in weight in previous months. This patient had a past history of surgery for nasal mucosal malignant melanoma 2 years ago. Abdominal enhanced computed tomography (CT) indicated that a mass originated from small bowel and occupied the left upper abdomen. The patient underwent a laparotomy during which a black lesion measuring about 5 cm × 5 cm × 4 cm was found at the jejunum and resected totally together with partial jejunum. The patient was eventually diagnosed as secondary jejunal malignant melanoma from nasal mucosal melanoma. For patients with a history of melanoma, gastrointestinal metastasis should be considered when patients develop gastrointestinal symptoms. In addition, we recommend positive anti-tumor therapy after surgery.


2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Ruty Eulália de Medeiros Eufrásio ◽  
Rannapaula Lawrynhuk Urbano Ferreira ◽  
Leilane Lílian Araújo Leal ◽  
Erikarla Baracho Avelino ◽  
Rafaela Nayara da Costa Pelonha ◽  
...  

Abstract Background Ballet dancers are a risk group for body image (BI) distortion, dissatisfaction and eating disorders (ED), but few studies have investigated these aspects in amateur adult practitioners. This study aimed to evaluate if amateur female adult classical ballet dancers presented different BI and behaviors for ED than gym users and sedentary women. Methods This is a cross-sectional study where classical ballet dancers (n = 19) were compared to gym users (n = 19) and sedentary women (n = 19). Body mass index (BMI) was assessed, and a figure rating scale was applied to assess BI distortion/dissatisfaction. The body shape questionnaire (BSQ) was used to measure BI concern. The eating attitudes test (EAT-26) and the bulimic investigatory test, Edinburgh (BITE) were used for behaviors toward anorexia and bulimia. Results BMI was significantly lower in ballet dancers than gym users and sedentary women (F, p = .04). BI distortion did not differ among the studied groups. BI dissatisfaction was lower (X2, p = .041) in ballet dancers (75.0%) and gym users (70.6%) compared to sedentary women (100%). Correspondence analysis showed ballet dancers were mostly not concerned with BI, which was not observed among the other groups. The EAT-26 did not differ between the studied groups. The BITE score was lower (Tukey’s post hoc test, p = .005) in the ballet dancers [mean 5.3 (5.6)] compared to the sedentary women [mean 10.9 (4.8)]. Conclusions Data suggest that amateur classical ballet practicing is associated to better BI and fewer behaviors for ED in the studied population. The lower BMI in ballet dancers might explain these findings, and further studies should explore these associations.


2021 ◽  
Vol 4 (2) ◽  
pp. 01-19
Author(s):  
Anthony Kodzo-Grey Venyo

Hydatid cyst of the breast is a rare infection of the breast that tends to be reported sporadically in Echinococcus infection endemic areas; nevertheless, because of increasing global travel hydatid cyst of the breast may be encountered in a non-endemic area of the world where clinicians may not be familiar with the manifestation and biological behaviour of the disease. Hydatid cyst of the breast has been reported sporadically in females whose ages have ranged between 16 years and 87 years and these cases only represent 0.27% of all cases of hydatid cyst encountered globally. Hydatid cyst of the breast does present as a lump/mass in the breast which quite often tends to be painless but it could be associated with pain/discomfort. Hydatid cyst of the breast tends to present insidiously and the lump tends to be present for a long time before attention is sought by the patient because it had behaved innocuously and had either been growing slowly with a recent noticeable increase in size over a few months. A history of previous contact with dogs and sheep as well as present or previous residence in an echinococcus endemic area tends to be helpful in alerting the clinician to the possibility of the diagnosis of hydatid cyst. A past history of treatment for echinococcal infection elsewhere in the body would also be helpful in alerting the clinician to the diagnosis of the disease. There tends to be no family history of breast cancer, and no history of previous hormone replacement therapy. The general and systematic examinations of most of the patients tend to be normal unless they have other non-related medical conditions. Clinical examination usually tends to reveal a swelling that tends to be well-circumscribed with clear margin that may be non-tender but at times there may be tenderness associated with the lump. The clinical examination findings tend to be non-specific and would usually mimic fibroadenoma, phyllodes tumour, or intra-cystic carcinoma of the breast. Usually the results of routine haematology and haematology blood tests would tend to be normal unless there is a non-related disease but there could be eosinophilia. Echinococcus hemagglutination test and Elisa test for Echinococcal IgE test would tend to be positive in cases of hydatid cyst of the breast. Various radiology imaging modalities tend to be utilized to assess hydatid cyst of the breast including mammogram, ultrasound scan of the breast, computed tomography (CT) scan of the breast, thorax, and abdomen, magnetic resonance imaging (MRI) scan of breast, thorax, and abdomen. Diagnosis of hydatid cyst of the breast tends to be diagnosed by undertaking fine needle aspiration biopsy of the breast lesion for cytology/histopathology examination or histopathology examination of excised hydatid cysts of the breast. Successful treatment of hydatid cyst of the breast requires complete excision without spillage of the hydatid cyst and additionally to minimise recurrence of disease Albendazole medication tends to be given. When there is spillage of the hydatid cyst or rupture of the hydatid cyst during the process of the excision, a thorough lavage of the operating field and excision of the surrounding tissue to ensure any possible residual daughter cysts are completely removed and utilization of Albendazole medicament would help to minimize or avoid development of recurrence. Because of the possibility of recurrence of disease a period of follow-up assessment with clinical examination and radiology imaging assessment as well as echinococcus hemagglutination tests would be recommended.


2011 ◽  
Vol 19 (1) ◽  
pp. 31-33 ◽  
Author(s):  
Md Moniruzzaman Sarker ◽  
AKM Golam Kibria ◽  
Md Manzurul Haque

Rhinosporidiosis is a chronic granulomatous infection that frequently involves the nose and nasopharynx, and occasionally affects the other areas of the body. We report a 40-year-old patient who had disseminated subcutaneous rhinosporidiosis. The patient presented with multiple subcutaneous lesions over the different parts of the body during last five years. He had a past history of a lesion in his right nostril with nasal blockage and haemorrhage ten years back. In our surgical unit the patient had been subjected to elective operation with excision of subcutaneous lesions. The histopathology report of excised subcutaneous lesions was rhinosporidiosis. The patient is being followed up postoperatively.   doi: 10.3329/taj.v19i1.3166 TAJ 2006; 19(1): 31-33


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