scholarly journals Genetic and environmental risk factors for sexual distress and its association with female sexual dysfunction

2011 ◽  
Vol 41 (11) ◽  
pp. 2435-2445 ◽  
Author(s):  
A. Burri ◽  
Q. Rahman ◽  
T. Spector
Keyword(s):  
Risk Factors ◽  
Sexual Dysfunction ◽  
Environmental Risk ◽  
Female Sexual Dysfunction ◽  
Environmental Risk Factors ◽  
Bivariate Analysis ◽  
Obsessive Compulsive ◽  
General Anxiety ◽  
Sexual Distress ◽  
Potential Risk Factors

BackgroundThe DSM-V Working Group is currently re-evaluating distress as a primary diagnostic criterion for female sexual dysfunction (FSD). Here, for the first time, we explored the epidemiology of sexual distress and its putative aetiological relationship to FSD by estimating the influence of genetic and environmental risk factors.MethodQuestionnaire data on a representative sample of 930 British female twins using validated scales of FSD and sexual distress were subject to variance components analyses to quantify latent genetic and environmental factors influencing phenotypic variation and covariation. Multiple regression analyses were used to identify other potential risk factors of sexual distress.ResultsOf 319 women with any sexual problems, only 36.5% reported distress. Of women classified as functional, 16.5% felt sexual distress. Sexual distress had a heritability of 44% [95% confidence interval (CI) 0.33–0.54]. Bivariate analysis suggested that the majority (91% CI 86–99%) of the covariance between sexual distress and FSD was due to unique environmental effects common to both traits. Associations were found between sexual distress and other risk variables, including relationship dissatisfaction [odds ratio (OR) 1.6, p<0.001], anxiety sensitivity and obsessive–compulsive symptomatology (OR 1.2, p<0.01, for both).ConclusionsThere seems to be a weak phenotypic and genetic basis for including sexual distress as a diagnostic indicator of FSD. Instead, the data indicate that unrelated psychological factors play an important role in sexual distress and tentatively suggest that sexual distress is less a consequence of FSD and more related to general anxiety among women.

The Prevalence of Female Sexual Dysfunction and Potential Risk Factors That May Impair Sexual Function in Turkish Women

2004 ◽  
Vol 72 (1) ◽  
pp. 52-57 ◽  
Author(s):  
Selahittin Çayan ◽  
Erdem Akbay ◽  
Murat Bozlu ◽  
Bülent Canpolat ◽  
Deniz Acar ◽  
...  
Keyword(s):  
Risk Factors ◽  
Sexual Dysfunction ◽  
Sexual Function ◽  
Potential Risk ◽  
Female Sexual Dysfunction ◽  
Turkish Women ◽  
Potential Risk Factors

scholarly journals Study of clinical profile of acute lower respiratory tract infection in children aged 2 months to 5 years

2018 ◽  
Vol 5 (4) ◽  
pp. 1322
Author(s):  
Dhivyanarayani M. ◽  
Raju V. ◽  
Jeyachandran P.
Keyword(s):  
Risk Factors ◽  
Respiratory Tract ◽  
Environmental Risk ◽  
Potential Risk ◽  
Lower Respiratory Tract ◽  
Environmental Risk Factors ◽  
Clinical Profile ◽  
Nutritional Risk ◽  
Potential Risk Factors ◽  
Tract Infections

Background: Acute respiratory infections are a leading cause of morbidity and mortality in under-five chil-dren in developing countries. Hence, the present study was undertaken to study the various risk factors, clinical profile and outcome of acute lower respiratory tract infections (ALRI) in children aged 2 months to 5 years. To study the risk factors associated with ALRI in these children. To ascertain the association of the various cultural practices prevalent in this area with ALRI.Methods: 100 ALRI cases fulfilling WHO criteria for pneumonia, in the age group of 2 months to 5 years were evaluated for potential risk factors, clinical profile and outcome as per a predesigned proforma in a rural medical college.Results: Socio-demographic risk factors like parental illiteracy, overcrowding, partial immunization and low socioeconomic status were potential risk factors; similarly, nutritional risk factors like early and late weaning, anemia, and malnutrition were associated with ALRI. Significant environmental risk factors were the use of biomass fuels, inadequate ventilation at home, and lack of separate kitchen.Conclusions: The present study has identified various socio-demographic, nutritional and environmental risk factors for ALRI which can be tackled by effective health education of the community and effective training of peripheral health personnel.

scholarly journals Are punitive parenting and stressful life events environmental risk factors for obsessive-compulsive symptoms in youth? A longitudinal twin study

2018 ◽  
Vol 56 (1) ◽  
pp. 35-42 ◽  
Author(s):  
G.C. Krebs ◽  
L.J. Hannigan ◽  
A.M. Gregory ◽  
F.V. Rijsdijk ◽  
B. Maughan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Life Events ◽  
Environmental Risk ◽  
Stressful Life Events ◽  
Environmental Risk Factors ◽  
Genetic Models ◽  
Self Report ◽  
Stressful Life ◽  
Obsessive Compulsive ◽  
Obsessive Compulsive Symptoms

AbstractBackground:Punitive parenting and stressful life events are associated with obsessive-compulsive symptoms (OCS). However, the lack of longitudinal, genetically-informative studies means it remains unclear whether these factors represent environmentally-mediated risks for the development of OCS.Methods:Twins and siblings from the Genesis1219 study completed self-report questionnaires two years apart (Time 1: N = 2616, mean age = 15.0; Time 2: N = 1579, mean age = 17.0 years) assessing OCS, maternal and paternal punitive parenting, and dependent stressful life events. Multiple regression models tested cross-sectional and longitudinal associations between the putative environmental risk factors and obsessive-compulsive symptoms using: (a) individual scores; and (b) monozygotic twin difference scores. The aetiologies of significant phenotypic associations between putative risk factors and OCS were further examined using multivariate genetic models.Results:At a phenotypic level, maternal and paternal punitive parenting and stressful life events were all associated with OCS both cross-sectionally and longitudinally. However, only stressful life events predicted the subsequent development of OCS, after controlling for earlier symptoms. Genetic models indicated that the association between life events and change in OCS symptoms was due to both genetic (48%) and environmental (52%) influences. Overall, life events associated with change in OCS accounted for 1.2% of variation in OCS at Time 2.Conclusions:Stressful life events, but not punitive parenting, predict OCS change during adolescence at a phenotypic level. This association exists above and beyond genetic confounding, consistent with the hypothesis that stressful life events play a causal role in the development of obsessive-compulsive symptoms.

Risk Factors for Female Sexual Dysfunction in the General Population: Exploring Factors Associated with Low Sexual Function and Sexual Distress

2008 ◽  
Vol 5 (7) ◽  
pp. 1681-1693 ◽  
Author(s):  
Richard D. Hayes ◽  
Lorraine Dennerstein ◽  
Catherine M. Bennett ◽  
Mohsin Sidat ◽  
Lyle C. Gurrin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Sexual Dysfunction ◽  
General Population ◽  
Sexual Function ◽  
Female Sexual Dysfunction ◽  
Factors Associated ◽  
Sexual Distress

scholarly journals Epidemiology and risk factors for bipolar disorder

2018 ◽  
Vol 8 (9) ◽  
pp. 251-269 ◽  
Author(s):  
Tobias A. Rowland ◽  
Steven Marwaha
Keyword(s):  
Risk Factors ◽  
Bipolar Disorder ◽  
Environmental Risk ◽  
Population Level ◽  
Environmental Risk Factors ◽  
Mental Illnesses ◽  
Sufficient Evidence ◽  
Specific Gene ◽  
Potential Risk Factors ◽  
Genetic And Environmental Factors

Bipolar disorder is a multifactorial illness with uncertain aetiology. Knowledge of potential risk factors enables clinicians to identify patients who are more likely to develop bipolar disorder, which directs further investigation, follow up and caution when prescribing. Ideally, identifying directly causative factors for bipolar disorder would enable intervention on an individual or population level to prevent the development of the illness, and improve outcomes through earlier treatment. This article reviews the epidemiology of bipolar disorder, along with putative demographic, genetic and environmental risk factors, while assessing the strength of these associations and to what extent they might be said to be ‘causative’. While numerous genetic and environmental risk factors have been identified, the attributable risk of individual factors is often small, and most are not specific to bipolar disorder but are associated with several mental illnesses. Therefore, while some genetic and environmental factors have strong evidence supporting their association with bipolar disorder, fewer have sufficient evidence to establish causality. There is increasing interest in the role of specific gene–environment interactions, as well as the mechanisms by which risk factors interact to lead to bipolar disorder.

scholarly journals Environmental factors associated with childhood norovirus diarrhoea in León, Nicaragua

2017 ◽  
Vol 145 (8) ◽  
pp. 1597-1605 ◽  
Author(s):  
S. BECKER-DREPS ◽  
C. C. CUTHBERTSON ◽  
F. BUCARDO ◽  
J. VINJE ◽  
M. PANIAGUA ◽  
...  
Keyword(s):  
Risk Factors ◽  
Environmental Factors ◽  
Environmental Risk ◽  
Low Income ◽  
Population Based ◽  
Environmental Risk Factors ◽  
Bivariate Analysis ◽  
Buffer Zones ◽  
Factors Associated ◽  
Spatial Locations

SUMMARYNorovirus is detected in one in five diarrhoea episodes in children, yet little is known about environmental risk factors associated with this disease, especially in low-income settings. The objective of this study was to examine environmental risk factors, and spatial and seasonal patterns of norovirus diarrhoea episodes in children in León, Nicaragua. We followed a population-based cohort of children under age 5 years for norovirus diarrhoea over a 1-year period. At baseline, characteristics of each household were recorded. Households were geocoded and spatial locations of garbage dumps, rivers, and markets were collected. In bivariate analysis we observed younger children and those with animals in their households were more likely to have experienced norovirus episodes. In adjusted models, younger children remained at higher risk for norovirus episodes, but only modest associations were observed with family and environmental characteristics. We next identified symptomatic children living in the same household and within 500 m buffer zones around the household of another child infected with the same genotype. Norovirus diarrhoea episodes peaked early in the rainy season. These findings contribute to our understanding of environmental factors and norovirus infection.

scholarly journals Risk factors associated with female sexual dysfunction among married women in Upper Egypt; a cross sectional study

2018 ◽  
Vol 5 (2) ◽  
pp. 449
Author(s):  
Ahmed E. Arafa ◽  
Rasha S. Elbahrawe ◽  
Sherwet M. Shawky ◽  
Alshimaa M. Mostafa ◽  
Safaa S. Ahmed ◽  
...  
Keyword(s):  
Risk Factors ◽  
Sexual Dysfunction ◽  
Potential Risk ◽  
Female Sexual Dysfunction ◽  
Cross Sectional Study ◽  
Negative Consequences ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Potential Risk Factors

Background: Female sexual dysfunction (FSD) has many psychological and social negative consequences. The aim of this study is to detect the potential risk factors associated with FSD among sexually active women in Beni-Suef, Egypt. Methods: A multi-stage random sampling methodology was used to include 490 premenopausal women, residing in Beni-Suef, in this cross-sectional study. FSD was measured using the Arabic version of the female sexual function index (ArFSFI), throughout an interview. It includes 6 domains; desire, arousal, lubrication, orgasm, satisfaction and pain. The questions in each domain have five to six choices with a score ranging between zero and five. Results: Age, years of marriage and number of pregnancies correlated negatively with ArFSFI total score (p<0.05). Higher body mass index was associated with lower scores of desire, arousal and lubrication (p<0.05). Compared to those with constant job, unemployed women had lower scores of desire and arousal (p<0.05). No statistically significant associations have been detected between circumcision and any of the studied ArFSFI domains (p>0.05). Conclusions: There are many potential risk factors suggested to be associated with FSD. Further studies should focus on understanding the adaptive strategies used by women to get over their FSD problems. Barriers preventing women with FSD from seeking treatment should also be investigated. 

The prevalence of female sexual dysfunction and potential risk factors that may impair sexual function

2002 ◽  
Vol 1 (1) ◽  
pp. 150
Author(s):  
Selahittin Cayan ◽  
Erdem Akbay ◽  
Bülent Campolat ◽  
Deniz Acar ◽  
Murat Bozlu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Sexual Dysfunction ◽  
Sexual Function ◽  
Potential Risk ◽  
Female Sexual Dysfunction ◽  
Potential Risk Factors
Sign in / Sign up

Export Citation Format

Share Document