scholarly journals Cognitive reserve as a moderator of the negative association between mood and cognition: evidence from a population-representative cohort

2017 ◽  
Vol 48 (1) ◽  
pp. 61-71 ◽  
Author(s):  
C. Opdebeeck ◽  
F. E. Matthews ◽  
Y-T. Wu ◽  
R. T. Woods ◽  
C. Brayne ◽  
...  

BackgroundCognitive reserve (CR) has been associated with better cognitive function and lower risk of depression in older people, yet it remains unclear whether CR moderates the association between mood and cognition. This study aimed to investigate whether a comprehensive indicator of CR, including education, occupation and engagement in cognitive and social activities, acts as a moderator of this association.MethodsThis was a cross-sectional study utilising baseline data from the Cognitive Function and Ageing Study II (CFAS II), a large population-based cohort of people aged 65+ in England. Complete data on the measures of CR, mood and cognition were available for 6565 dementia-free individuals. Linear regression models were used to investigate the potential modifying effect of CR on the association between cognition and mood with adjustment for age, sex and missing data.ResultsLevels of CR did moderate the negative association between mood and cognition; the difference in cognition between those with and without a clinical level mood disorder was significantly smaller in the middle (−2.28; 95% confidence interval (CI) −3.65 to −0.90) and higher (−1.30; 95% CI −2.46 to −0.15) CR groups compared with the lower CR group (−4.01; 95% CI −5.53 to −2.49). The individual components of CR did not significantly moderate the negative association between mood and cognition.ConclusionThese results demonstrate that CR, indexed by a composite score based on multiple indicators, can moderate the negative association between lowered mood and cognition, emphasising the importance of continuing to build CR across the lifespan in order to maintain cognitive health.

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1639
Author(s):  
Zhongyao Li ◽  
Dongqing Wang ◽  
Edward A. Ruiz-Narváez ◽  
Karen E. Peterson ◽  
Hannia Campos ◽  
...  

Only a few studies primarily examined the associations between starchy vegetables (other than potatoes) and metabolic syndrome (MetS). We aimed to evaluate the association between starchy vegetables consumption and MetS in a population-based sample of Costa Rican adults. We hypothesized that a higher overall intake of starchy vegetables would not be associated with higher MetS prevalence. In this cross-sectional study, log-binomial regression models were used to estimate prevalence ratios (PRs) of MetS across quintiles of total, unhealthy, healthy starchy vegetables, and individual starchy vegetables (potatoes, purple sweet potatoes, etc.), among 1881 Costa Rican adults. Least square means and 95% confidence intervals (CIs) from linear regression models were estimated for each MetS component by categories of starchy vegetable variables. Higher intakes of starchy vegetables were associated with a higher prevalence of MetS in crude models, but no significant trends were observed after adjusting for confounders. A significant inverse association was observed between total starchy and healthy starchy vegetables consumption and fasting blood glucose. In this population, starchy vegetables might be part of a healthy dietary pattern.


2018 ◽  
Vol 95 (5) ◽  
pp. 682-690 ◽  
Author(s):  
M. Asadi-Lari ◽  
Y. Salimi ◽  
M. R. Vaez-Mahdavi ◽  
S. Faghihzadeh ◽  
A. A. Haeri Mehrizi ◽  
...  

BMJ Open ◽  
2017 ◽  
Vol 7 (5) ◽  
pp. e013548 ◽  
Author(s):  
Masoomeh Alimohammadian ◽  
Azam Majidi ◽  
Mehdi Yaseri ◽  
Batoul Ahmadi ◽  
Farhad Islami ◽  
...  

SLEEP ◽  
2021 ◽  
Author(s):  
Xin Liu ◽  
Guowei Wang ◽  
Xiaoyan Wang ◽  
Yueye Wang ◽  
Yan Min ◽  
...  

Abstract Study Objectives To investigate the association between daytime napping and retinal microcirculation. Methods This is a cross-sectional study from a prospective population-based cohort. 2,662 participants were recruited after quota sampling. Information on napping was collected through face-to-face interviews. Retinal vascular calibers (RVCs), including central retinal arteriolar equivalent (CRAE), central retinal venular equivalent (CRVE), and arterio-to-venous ratio (AVR), were obtained from fundus photography. Multivariate regression and restricted cubic spline curve were performed to determine the association between RVCs and daytime napping duration. Results 56.4% participants reported daytime napping regularly. Compared to no nap, daytime nap was related to higher CRAE, with nap duration of 0.5–1 h showing the most significant association. 0.5–1 h daytime nappers displayed an average of 4.18 µm (95% confidence interval [CI] 2.45–5.91, p < 0.001) wider CRAE than non-nappers after adjustment. No significant association was found between CRVE and daytime napping. Moreover, individuals with 0.5–1 h daytime napping had a lower risk for AVR reduction (odds ratio [OR] 0.70, 95% confidence interval [CI] 0.56–0.86, p = 0.001) than non-nappers. Similar association persisted in non-hypertensive population. Restricted cubic spline indicated a J-shaped relationship between AVR reduction and nap duration. Conclusion Retinal microcirculation was positively associated with self-reported 0.5–1 h daytime napping. Better indicators of retinal microcirculation were probably related to nap duration in a J-shaped manner. Also, the possibly beneficial role of 0.5–1 h daytime napping on retinal microcirculation might be independent of clinically diagnosed vascular diseases.


2020 ◽  
Vol 16 (S6) ◽  
Author(s):  
Shama D. Karanth ◽  
Yuriko Katsumata ◽  
Peter T. Nelson ◽  
Richard J. Kryscio ◽  
Frederick A Schmitt ◽  
...  

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