A Short Mental Status Questionnaire

Author(s):  
Duncan Robertson ◽  
Kenneth Rockwood ◽  
Paul Stolee

ABSTRACTA mental status questionnaire (MSQ) developed tor use in surveys of the non-institutionalized elderly has been validated against clinical assessment. The MSQ identities moderate and severe cognitive impairment in the elderly. However, using the suggested scoring subjects with mild impairment cannot be separated from normals.The test is short, acceptable and reproducible and rate for false-positives and false-negatives fall well within acceptable limits for use in estimating the prevalence of dementia in the non-institutionalized elderly population.

2017 ◽  
Vol 20 (2) ◽  
pp. 186-196 ◽  
Author(s):  
Fabienne Louise Juvêncio Paes de Andrade ◽  
Joelmma Maria Rebouça de Lima ◽  
Kalyne do Nascimento Moreira Fidelis ◽  
Javier Jerez-Roig ◽  
Kenio Costa de Lima

Abstract Objective: To identify the prevalence of cognitive impairment and associated factors among institutionalized elderly persons. Methods: A cross-sectional study was conducted from October to December 2013 in Long-Term Care Facilities for the elderly in Natal, Rio Grande do Norte, Brazil, featuring 326 elderly persons of both genders. The assessment of cognitive decline was classified using the Pfeiffer test. Information on sociodemographic conditions and health status was also recorded. Nutritional status was assessed by applying the Mini Nutritional Assessment tool and functional capacity with the Katz Index. To identify the factors associated with the presence of moderate or severe cognitive impairment multiple logistic regression analysis of variables with a p value >0.20 was performed, using the Stepwise Forward method. Results: It was observed that 83.6% (95% CI: 78.9 to 87.3%) of the elderly persons had cognitive impairment. The final model, adjusted for type of LTCF, showed that being 83 years old or older was considered a risk factor for moderate or severe cognitive impairment. However, having systemic arterial hypertension (SAH) and having been institutionalized through their own choice were considered protective factors for moderate or severe cognitive impairment. Conclusion: the variables age, having SAH and having been institutionalized through their own choice are directly associated, as risk or protection factors, with the presence of severe or moderate cognitive impairment of the elderly population. The early diagnosis of these factors can lead to greater focus in setting goals for prevention and health care, thus improving the quality of life of these individuals.


2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Longbing Ren ◽  
Yongtao Zheng ◽  
Lezhou Wu ◽  
Yijun Gu ◽  
Yusheng He ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-14
Author(s):  
Jing Yan ◽  
Ailin Luo ◽  
Rao Sun ◽  
Xiaole Tang ◽  
Yilin Zhao ◽  
...  

Postoperative cognitive dysfunction (POCD) is a sever postsurgical neurological complication in the elderly population. As the global acceleration of population ageing, POCD is proved to be a great challenge to the present labor market and healthcare system. In the present study, our findings showed that tau acetylation mediated by SIRT1 deficiency resulted in tau hyperphosphorylation in the hippocampus of the aged POCD model and consequently contributed to cognitive impairment. Interestingly, pretreatment with resveratrol almost restored the expression of SIRT1, reduced the levels of acetylated tau and hyperphosphorylated tau in the hippocampus, and improved the cognitive performance in the behavioral tests. What is more, we observed that microglia-derived neuroinflammation resulting from SIRT1 inhibition in microglia probably aggravated the tau acetylation in cultured neurons in vitro. Our findings supported the notion that activation SIRT1 provided dually beneficial effect in the aged POCD model. Taken together, our findings provided the initial evidence that tau acetylation was associated with cognitive impairment in the aged POCD model and paved a promising avenue to prevent POCD by inhibiting tau acetylation in a SIRT1-dependent manner.


2008 ◽  
Vol 66 (4) ◽  
pp. 809-813 ◽  
Author(s):  
Keithlen Cruz Moreira de Castro ◽  
Ricardo Oliveira Guerra

Functional incapacity and cognitive impairment are conditions related to the process of human aging. Cognitive impairment is considered an important predicitve factor for functional impairment in elderly populations. This cross-sectional study analyzes the association between cognitive performance and functional capacity in an elderly population sample in Natal, Brazil. A total of 213 elderly persons were assessed by the BOAS Multidimensional Questionnaire (Brazil Old Age Schedule) and the Mini-Mental State Examination (MMSE). The results of multivariate analysis and linear regression showed that age and schooling level are factors associated with cognitive performance in the elderly of this study. The final explicative model, elaborated by logistic regression, found that cognitive performance was the only predicitve variable of functional incapacity for the activities of daily living even when adjusted for sociodemographic variables.


2015 ◽  
Vol 45 (4) ◽  
pp. 257-263 ◽  
Author(s):  
Xiaoniu Liang ◽  
Xiantao Li ◽  
Ding Ding ◽  
Qianhua Zhao ◽  
Jianfeng Luo ◽  
...  

Background: Anthropometric indexes are powerful indicators of the environment and the plasticity of the human body. This study aimed at exploring the anthropometric indexes that are associated with late-life cognition impairment among the elderly Chinese in the Shanghai Aging Study. Methods: The height, weight, and sitting height of 3,741 participants were measured. Participants were diagnosed with ‘dementia', ‘mild cognitive impairment', or ‘cognitive normal' by neurologists using DSM-IV and Petersen criteria. Logistic regression was used to evaluate the association between height, sitting height, leg length or relative sitting height and cognitive function. Results: Participants with dementia had the shortest body height (mean 157.2 cm, SD 9.1), the shortest sitting height (mean 81.8 cm, SD 5.6), and the lowest relative sitting height (mean 52.0 cm, SD 1.9). After adjustment for age, gender, education, lifestyles, medical history, apolipoprotein genotype and weight, shorter sitting height (OR 1.08, 95% CI 1.01-1.16 per cm), longer leg length (OR 0.93, 95% CI 0.88-0.99 per cm), and lower relative sitting height (OR 1.17, 95% CI 1.04-1.31 per 1%) were found to be significantly associated with dementia in older women. Conclusions: The potential risks for late-life severe cognitive impairment may be related to health problems in childhood and slow growth during puberty in women.


2021 ◽  
Author(s):  
Gea Pandhita ◽  
Prasila Darwin ◽  
Bety Lakhsmi

Abstract Background: The increase in the elderly population in a developing country like Indonesia will increase people with cognitive impairment. Mild Cognitive Impairment (MCI) is the most common cognitive impairment among the elderly. However, some health workers are not satisfied with the current tools for detecting MCI in the community.Objective: This study intends to develop a novel, easy, and accurate method for early detection of MCI of the elderly population in the community in Indonesia.Methods: This study analyzed the database of 110 elderly population in East Jakarta, Indonesia. We explored several brief neuropsychiatric battery and developed a neuropsychiatric score to detect MCI.Results: The abnormal verbal semantic fluency test (p = 0.000), the existence of subjective memory complaints (p = 0.007), and low education level (p = 0.049) were found to be good predictors to detect MCI. The neuropsychiatric score, a combination of those variables, with a cut-off point of 2, has good accuracy to detect MCI (Sensitivity = 91.20%; Specificity = 78.9%).Conclusion: The neuropsychiatric score is a novel, easy, and accurate method for early detection of MCI of the elderly population in the community in Indonesia.


2018 ◽  
Vol 2 (1) ◽  

Aims: Alcohol is consumed excessively by almost a quarter of the population. A report by highlighted underdiagnosis of alcohol misuse in the elderly [1]. There is a lack of research focusing on assessment of alcohol use and its impact in older people. This study aimed to assess the validity of the Alcohol-Use-Disorder-Identification-Test (AUDIT) in an elderly population with cognitive impairment and to establish the validity of a novel adaption of the AUDIT used as a proxy measure. Methods: Opportunistic observational study examining the assessment of alcohol consumption in an elderly population with mild cognitive impairment or mild dementia. The study aimed to evaluate the self-report AUDIT versus a “proxy” AUDIT compared to a plasma Carbohydrate-deficientTransferrin (CDT) level. Findings: Scores were comparable between the “proxy” AUDIT and the AUDIT. Neither measure of alcohol intake correlated significantly with CDT levels. There was no association between alcohol intake and cognition or quality of life ratings. Conclusions: We suggest the AUDIT could be a useful screening tool in detecting alcohol misuse in the elderly with cognitive impairment. The “proxy” AUDIT was also found to be a valid screening tool, however further work is needed to confirm these findings.


2020 ◽  
Author(s):  
Francesco Iodice ◽  
Valeria Cassano ◽  
Paolo Maria Rossini

Abstract This article reviews the main articles that have been published so far about the direct and indirect effects of the COVID-19 pandemic on a particularly fragile population represented by the healthy elderly people as well as those with Mild Cognitive Impairment and Alzheimer's disease. Such populations have been among the most affected in the early stages of the pandemic due to the direct effects of the virus and numerous indirect effects now emerge and will have to be carefully assessed over time. The pandemic associated to COVID-19 has shifted most of the health resources to the emergency area and has consequently left the three main medical areas that dealing with the elderly population (oncology, time-dependent diseases and degenerative disease) temporarily “uncovered”. In the phase following the emergency, it will be crucial to guarantee to each area the economic and organizational resources to quickly return to the level of support of the pre-pandemic state. The emergency phase represented an important moment of discussion on the possibilities of telemedicine which will inevitably become increasingly important but all the limits of its use in the elderly population have to be considered. In the post-lockdown recovery phase, alongside the classic medical evaluation, the psychological evaluation must become even more important for doctors caring about people with cognitive decline.


2017 ◽  
Vol 70 (16) ◽  
pp. C71-C72
Author(s):  
Longbing Ren ◽  
Yongtao Zheng ◽  
Yijun Gu ◽  
Yusheng He ◽  
Bo Jiang ◽  
...  

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