scholarly journals Prevalence of hepatitis B infection markers in Lebanese children: the need for an expanded programme on immunization

2001 ◽  
Vol 126 (2) ◽  
pp. 285-289 ◽  
Author(s):  
M. M. NABULSI ◽  
G. F. ARAJ ◽  
I. NUWAYHID ◽  
M. RAMADAN ◽  
M. ARISS
Keyword(s):  
Hepatitis B ◽  
Hepatitis B Surface Antigen ◽  
Horizontal Transmission ◽  
Cross Sectional Study ◽  
Family Characteristics ◽  
Hepatitis B Infection ◽  
Childhood Immunization ◽  
Cross Sectional ◽  
South Lebanon ◽  
Infection Markers

This multi-centre, cross-sectional study was designed to reveal the present status of hepatitis B infection markers among Lebanese children, and provide recommendations regarding childhood immunization policies. A total of 841 children, aged between 6 months and 6·5 years, were enrolled from Lebanon's five districts. Their sera were tested for hepatitis B surface antigen and hepatitis B core IgG. The overall prevalence of hepatitis B virus infection markers was 0·8 % with increasing age-specific rates from 0 % at 6 months to 1·3 % at > 5 years. There was no statistically significant association between the presence of hepatitis B markers and family characteristics or risk factors for infection. The highest prevalence rates were among children from Beirut suburbs (2·9 %) and South Lebanon (1·6 %). The risk of horizontal transmission of hepatitis B to uninfected children increased substantially after the age of 2 years. An expanded programme on immunization that integrates hepatitis B vaccine during the first year of life is needed.

scholarly journals Liver Fibrosis and Hepatitis B Coinfection among ART Naïve HIV-Infected Patients at a Tertiary Level Hospital in Northwestern Tanzania: A Cross-Sectional Study

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Semvua B. Kilonzo ◽  
Daniel W. Gunda ◽  
Flora Kashasha ◽  
Bonaventura C. Mpondo
Keyword(s):  
Liver Fibrosis ◽  
Hepatitis B ◽  
Aspartate Aminotransferase ◽  
Hepatitis B Surface Antigen ◽  
Clinical Information ◽  
Cross Sectional Study ◽  
Hepatitis B Infection ◽  
Cross Sectional ◽  
Northwestern Tanzania ◽  
Increased Risk

Background. Liver fibrosis which is a common complication of chronic hepatitis B infection is rarely diagnosed in low-resource countries due to limited capacity to perform biopsy studies. Data on the utilization of noninvasive techniques which are feasible for diagnosis of liver fibrosis in these settings among HIV-infected patients is scarce. The objective of this study was to establish the magnitude of liver fibrosis by using both aspartate-aminotransferase-to-platelets ratio and fibrosis-4 scores with associated hepatitis B coinfection among antiretroviral therapy naïve HIV-infected patients. Methods. We reviewed data of 743 adult patients attending HIV clinic with available hepatitis B surface antigen test results. Baseline clinical information was recorded and aspartate-aminotransferase-to-platelet ratio and fibrosis-4 scores were calculated. The cut-off values of 1.5 and 3.25 were used for diagnosis of significant fibrosis by aspartate-aminotransferase-to-platelets ratio and fibrosis-4 scores, respectively. Results. The prevalence of liver fibrosis was 3.5% when aspartate-aminotransferase-to-platelet score was used and 4.6% with fibrosis-4 score and they were both significantly higher among patients with hepatitis B coinfection. Younger patients with HIV advanced disease and elevated liver transaminases had increased risk of having hepatitis B coinfection. Conclusion. A remarkable number of HIV-infected patients present with liver fibrosis, predominantly those with hepatitis B infection.

scholarly journals Risk perception and knowledge of hepatitis B infection among cleaners in a tertiary hospital in Nigeria: A cross-sectional study

2019 ◽  
Vol 7 (1) ◽  
pp. 11-16 ◽  
Author(s):  
Olumide Abiodun ◽  
Olusola Shobowale ◽  
Charles Elikwu ◽  
Daniel Ogbaro ◽  
Adebola Omotosho ◽  
...  
Keyword(s):  
Risk Perception ◽  
Hepatitis B ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Hepatitis B Infection ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Prevalence and risk factors of hepatitis B virus transmission among children in Enugu, Nigeria

1970 ◽  
Vol 42 (3) ◽  
pp. 199-203
Author(s):  
ND Uleanya ◽  
EO Obidike
Keyword(s):  
Risk Factors ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Surface Antigen ◽  
Hepatitis B Surface Antigen ◽  
Virus Transmission ◽  
Cross Sectional Study ◽  
Sub Saharan Africa ◽  
Cross Sectional ◽  
B Virus

Background: Hepatitis B Virus (HBV) infection has reached pandemic proportions all over the world with areas of highest prevalence being the sub- Saharan Africa and Southeast Asia. Most deaths related to HBV are due to complications from chronic infection. Acquisition of infection at a younger age is the most important predictor of chronicity. Eradication of HBV is an important but difficult tasks facing public health. HB immunization is the single most important factor in hepatitis B control and was commenced in 2004 in Nigeria.Objectives: To determine the prevalence of Hepatitis B surface antigen (HBsAg) among children in the era of HB immunization, the risk factors of transmission and knowledge of mothers about their HB status.Methods: A cross sectional study carried out on one hundred and forty children aged 18 months to 15 years at the children outpatient clinic (CHOP) of the University of Nigeria Teaching Hospital, Ituku. Hepatitis B surface antigen (HBsAg) was determined using Determine Test Kits and a structured interviewer administered questionnaire administered.Results: Six were positive for HBsAg, giving a prevalence rate of 4.3%. HBsAg was least prevalent among children 1-5 years (2%). None of the children ≤ 5 years who received HB vaccination was positive for HBsAg though one child > 5 years who received the vaccine was positive. Sharing of toothbrushes among siblings was found to be a significantly associated risk factor. Only 6.4% of mothers knew their hepatitis B status.Conclusion: There is a gradual fall in the prevalence of HBsAg in our environment due to HB immunization. Sharing of toothbrushes may be a potent means of transmission of HBV infection.Keywords: HBV, Prevalence, Children, Transmission, HB immunization

scholarly journals Hepatitis B co-infection in HIV-infected patients receiving antiretroviral therapy at the TC Newman Anti Retroviral Treatment Clinic in Paarl, Western Cape

2016 ◽  
Vol 17 (1) ◽  
Author(s):  
Jeanmari King ◽  
Dirk T. Hagemeister
Keyword(s):  
Hepatitis B ◽  
Surface Antigen ◽  
Antiretroviral Treatment ◽  
Hepatitis B Surface Antigen ◽  
Routine Data ◽  
Cross Sectional Study ◽  
Cd4 Count ◽  
Western Cape ◽  
Cross Sectional ◽  
Treatment Clinic

Background: Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) co-infection in South Africa is estimated to be between 5% and 23%; however, only limited evidence is available. Co-infection increases the risk of chronification of HBV, liver cirrhosis and death.Objective: To assess the HBV and/or HIV co-infection rate amongst the adult antiretroviral treatment cohort at the TC Newman ART Clinic in Paarl, Western Cape.Methods: In a retrospective, cross-sectional study, the routine hepatitis B surface antigen screening results for all adult HIV patients who were started on antiretroviral treatment over a period of 19 months were collected and analysed for gender, CD4 count and age.Results: Amongst the 498 participants (60% female participants), the Hepatitis B surface Antigen positivity rate was 7.6%. Male gender, age between 50 and 59 years and a low CD4 count were correlated with higher rates.Conclusion: Useful insight could be obtained by analysing routine data. The prevalence of almost 8% confirms the need for testing of HIV-positive patients for hepatitis B.Keywords: hepatitis B; prevalence; HIV-infected; adults; co-infection

scholarly journals Perception and Practices relating to Hepatitis B Infection among In-school Adolescents in Ogun State, Nigeria

2021 ◽  
Vol 4 (1) ◽  
pp. 14-22
Author(s):  
Titilayo Olaoye ◽  
Catherine Agbede ◽  
Fredrick Oshiname
Keyword(s):  
Hepatitis B ◽  
Cross Sectional Study ◽  
Hepatitis B Infection ◽  
Unsafe Sex ◽  
Chi Square ◽  
Cross Sectional ◽  
Significance Level ◽  
Multiple Sexual Partners ◽  
Ogun State ◽  
Multi Stage

Objective: This study examined the perception and practices relating to Hepatitis B infection among In-school adolescents in Ogun State, Nigeria. Methods:  A cross-sectional study of 300 in-school adolescents selected by a multi-stage sampling method. Data were elicited using a pretested self-administered questionnaire which included questions relating to respondents' risky practices, and a 35-point Hepatitis B perception scale. Descriptive statistics, as well as Chi-square statistics, were generated using IBM SPSS Version 23, and the significance level was set at 0.05. Results: The mean age of the respondents was 14.31 ± 1.73years and slightly over half (51.7%) were females. Less than half (45%) of the adolescents perceived themselves to be susceptible to Hepatitis B infection, while 31% perceived Hepatitis B infection to be a serious disease. Almost half (49%) of the adolescents had unfavorable perceptions. The most common risky practices among the respondents were sharing skin-piercing instruments with their family members (79%) and friends (68.7%). There are significant associations between sex (gender) and risky practices such as the practices of unsafe sex (X2= 9.11; p=0.10); having multiple sexual partners (X2= 12.08; p =0.02); and sharing skin-piercing instruments (X2= 5.52; p=0.01) with more males reporting the above practices than females. Conclusion/Recommendation: To minimize the identified risky practices and unfavorable perception, educational intervention programs aimed at promoting Hepatitis B virus preventive behaviors and increasing the level of perception of vulnerability and seriousness of HBV infection among in-school adolescents should be conducted.

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