scholarly journals Online market research panel members as controls in case–control studies to investigate gastrointestinal disease outbreaks: early experiences and lessons learnt from the UK – ERRATUM

2018 ◽  
Vol 146 (12) ◽  
pp. 1611-1611
Author(s):  
P. Mook ◽  
J. McCormick ◽  
S. Kanagarajah ◽  
G. K. Adak ◽  
P. Cleary ◽  
...  
2018 ◽  
Vol 146 (4) ◽  
pp. 458-464 ◽  
Author(s):  
P. Mook ◽  
J. McCormick ◽  
S. Kanagarajah ◽  
G. K. Adak ◽  
P. Cleary ◽  
...  

AbstractEstablished methods of recruiting population controls for case–control studies to investigate gastrointestinal disease outbreaks can be time consuming, resulting in delays in identifying the source or vehicle of infection. After an initial evaluation of using online market research panel members as controls in a case–control study to investigate aSalmonellaoutbreak in 2013, this method was applied in four further studies in the UK between 2014 and 2016. We used data from all five studies and interviews with members of each outbreak control team and market research panel provider to review operational issues, evaluate risk of bias in this approach and consider methods to reduce confounding and bias. The investigators of each outbreak reported likely time and cost savings from using market research controls. There were systematic differences between case and control groups in some studies but no evidence that conclusions on the likely source or vehicle of infection were incorrect. Potential selection biases introduced by using this sampling frame and the low response rate are unclear. Methods that might reduce confounding and some bias should be balanced with concerns for overmatching. Further evaluation of this approach using comparisons with traditional methods and population-based exposure survey data is recommended.


2015 ◽  
Vol 144 (6) ◽  
pp. 1220-1230 ◽  
Author(s):  
P. MOOK ◽  
S. KANAGARAJAH ◽  
H. MAGUIRE ◽  
G. K. ADAK ◽  
G. DABRERA ◽  
...  

SUMMARYTimely recruitment of population controls in infectious disease outbreak investigations is challenging. We evaluated the timeliness and cost of using a market research panel as a sampling frame for recruiting controls in a case-control study during an outbreak of Salmonella Mikawasima in the UK in 2013. We deployed a web-survey by email to targeted members of a market research panel (panel controls) in parallel to the outbreak control team interviewing randomly selected public health staff by telephone and completing paper-based questionnaires (staff controls). Recruitment and completion of exposure history web-surveys for panel controls (n = 123) took 14 h compared to 15 days for staff controls (n = 82). The average staff-time cost per questionnaire for staff controls was £13·13 compared to an invoiced cost of £3·60 per panel control. Differences in the distribution of some exposures existed between these control groups but case-control studies using each group found that illness was associated with consumption of chicken outside of the home and chicken from local butchers. Recruiting market research panel controls offers time and resource savings. More rapid investigations would enable more prompt implementation of control measures. We recommend that this method of recruiting controls is considered in future investigations and assessed further to better understand strengths and limitations.


2015 ◽  
Vol 30 (6) ◽  
pp. 465-471 ◽  
Author(s):  
Alison Waldram ◽  
Caoimhe McKerr ◽  
Maya Gobin ◽  
Goutam Adak ◽  
James M. Stuart ◽  
...  

2016 ◽  
Vol 8 (1) ◽  
Author(s):  
Fernando Sánchez-Vizcaíno ◽  
Barry Rowlingson ◽  
Alan D Radford ◽  
Alison Hale ◽  
Emanuele Giorgi ◽  
...  

In human and animal health, conventional approaches to preventing and controlling gastrointestinal disease (GI) have not reduced the overall disease burden. In order to understand and mitigate shared GI aetiologies between humans and animals it is necessary to develop One Health Surveillance approaches that integrate data-sources contributed to by human and veterinary healthcare. Here we describe how a real-time surveillance system for early detection of GI outbreaks in small animal and human health is being developed by collecting electronic health records from veterinary practitioners and a telephone-based 24-hour medical triage service in the UK.


2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
Y.-R. Kim ◽  
J. Treasure

Objective:The aim of this study was to investigate the characteristics of the risk factors for anorexia nervosa (AN) in East Asian subjects.Method:Two sets of case-control comparisons were conducted, in which 33 women with lifetime AN from Seoul, S. Korea, were compared with 42 women with lifetime AN from the UK and also with 90 Korean healthy controls in terms of their childhood risk factors. A questionnaire designed to conduct retrospective assessments of the childhood risk factors was administered to all participants.Results:There were no overall differences in the childhood risk factors between the Korean and British women with AN. The Korean AN patients were more likely to report premorbid anxiety, perfectionism and emotional undereating and were less likely to report having supportive figures in their childhood than the healthy controls.Conclusion:Our findings support the theory that AN is not a culture-bound syndrome. Larger epidemiologically based studies would be needed to validate these preliminary findings.


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