scholarly journals Potentially inappropriate prescription of antidepressants in old people: characteristics, associated factors, and impact on mortality

2017 ◽  
Vol 30 (5) ◽  
pp. 715-726 ◽  
Author(s):  
Anne Hiance-Delahaye ◽  
Florence Muller de Schongor ◽  
Laurent Lechowski ◽  
Laurent Teillet ◽  
Jean-Jacques Arvieu ◽  
...  
Keyword(s):  
Chronic Diseases ◽  
Associated Factors ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Cox Model ◽  
Inappropriate Prescribing ◽  
Multivariate Logistic Regression Model ◽  
Old People ◽  
Cross Sectional ◽  
Study Population

ABSTRACTBackground:The increasing use of antidepressants (ADs) has raised concerns about their inappropriate use in old people.Objective:To examine the prevalence of potentially inappropriate prescribing (PIP) of ADs, their associated factors, and their impact on mortality in a sample of old people in France.Methods:The analysis used data from the SIPAF study, a cross-sectional study consisting of 2,350 people aged ≥ 70 years. Trained nurses interviewed participants at home between 2008 and 2010. Information was collected concerning socio-demographic and health characteristics, including medication use. The study population consisted of the 318 AD users from the SIPAF study (13.5%). PIP of ADs was defined according to national and international criteria. Factors associated with PIP of ADs were assessed using a multivariate logistic regression model. The influence of PIP of ADs on mortality was assessed using a Cox model (median follow-up 2.8 years).Results:Among the SIPAF study, 71% of AD users were female and the mean age was 84 ± 7 years. Selective serotonin reuptake inhibitors (SSRIs) were the most prescribed ADs (19.8%). We found PIP of ADs in 36.8% of the study population, mainly the co-prescription of diuretics with SSRIs (17.6%) and the prescription of tricyclics (12.9%). PIP of ADs was associated with polypharmacy (aOR5-9 drugs 2. 61, 95% CI 1.11–6.16 and aOR≥10 drugs 2.69, 95% CI 1.06–6.87) and comorbidity (aOR3-4 chronic diseases 2.59, 95%CI 1.04–6.44 and aOR≥5 chronic diseases 2.33, 95%CI 0.94–5.79), and increased the risk of mortality during follow-up (aHR 2.30, 95%CI 1.28–4.12).Conclusions:This study shows that more than one third of AD prescriptions may be inappropriate in old people. PIP of ADs was related to polypharmacy and comorbidity and increased mortality among AD users.

scholarly journals Infertility and associated factors in three hospitals in Douala, Cameroon: a cross-sectional study

2020 ◽  
Vol 20 (4) ◽  
pp. 1985-95
Author(s):  
Thomas Obinchemti Egbe ◽  
Charmaine Ngo Mbaki ◽  
Nicholas Tendongfor ◽  
Elvis Temfack ◽  
Eugene Belley-Priso
Keyword(s):  
Associated Factors ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
Public Hospitals ◽  
Multivariate Logistic Regression Model ◽  
Toxic Substances ◽  
Sectional Study ◽  
Cross Sectional ◽  
Reproductive Tract Infection ◽  
History Of

Aim: We determined the prevalence and factors associated with couple infertility in three hospitals in Douala, Cameroon. Methods: We conducted a cross-sectional study from December 18th 2015 to March 18th 2016 in three public hospitals in Douala. Three hundred and sixty participants were studied prospectively for associated fac- tors using a multivariate logistic regression model and 4732 files were studied retrospectively for the prevalence of infertility. Statistical significance was set at p < 0.05. Results: The prevalence of couple infertility was 19.2%. In logistic models, the factors which independently increased the risk of couple infertility were a history of reproductive tract infection/STI, a history of uterine fibroids, a history of dys- menorrhea and abortion for the females while for males it was a history of mumps, erectile dysfunction and exposure to chemicals/toxic substances/pesticides. Conclusion: One in every five couples in this study was infertile. Several factors affect the risks associated with couple in- fertility. The identification of these factors could help detect subgroups of couples at high risk of infertility. Reproductive health education, screening programmes for STI’s that may lead to infertility should be offered to couples. Keywords: Couple infertility; prevalence; associated factors; Douala; Cameroon.

scholarly journals Person-Centered Maternity Care During Childbirth and Associated Factors at Selected Public Hospitals in Addis Ababa, Ethiopia, 2021: A Cross-Sectional Study

2021 ◽  
Author(s):  
Azezew Ambachew Tarekegne ◽  
Berhanu Wordofa Giru ◽  
Bazie Mekonnen
Keyword(s):  
Health Care Providers ◽  
Maternity Care ◽  
Associated Factors ◽  
Addis Ababa ◽  
Cross Sectional Study ◽  
Public Hospitals ◽  
Care Providers ◽  
Sectional Study ◽  
Cross Sectional

Abstract Background: Person-centered maternity care is respectful and responsive care to individual women’s preferences, needs, and values and ensuring that their values guide all clinical decisions during childbirth. It is recognized as a key dimension of the quality of maternity care that increases client satisfaction and institutional delivery. However, little research has been conducted about person-centered maternity care in Ethiopia. Objective: The aim of this study was to assess the status of person-centered maternity care and associated factors among mothers who gave birth at selected public hospitals in Addis Ababa city, Addis Ababa, Ethiopia, 2021.Method: A facility-based cross-sectional study was conducted at selected public hospitals in Addis Ababa city. A semi-structured questionnaire was used to collect data from post-natal mothers selected by systematic random sampling. The data was coded and entered using Epi-data version 4.6 and analyzed using SPSS version 25. Bivariate and multivariable linear regression analysis was used to identify factors associated with person-centered maternity care. The strength of association between independent and dependent variables was reported by using unstandardized β at 95% CI and p-value < 0.05 were considered statistically significant.Results: In this study 384 mothers were participated with a response rate of 99.2%. The overall prevalence of person-centered maternity care was 65.8%. Respondents who had no ANC follow-up (β= -5.39, 95% CI: -10.52, -0.26), <4 ANC follow up (β= -3.99, 95% CI: -6.63, -1.36), night time delivery (β= -3.95, 95% CI: -5.91, -1.98) and complications during delivery (β= -3.18, 95% CI: -6.01, -0.35) were factors significantly associated with person-centered maternity care.Conclusion and Recommendations: The finding of this study showed that the proportion of person-centered maternity care among mothers who gave birth in public hospitals of Addis Ababa was high as compared to previous studies. The factors affecting person-centered maternity care are manageable to interventions. Therefore, Health care providers need to provide person-centered maternity care for all mothers.

Management Outcome of Uterine Rupture and Associated Factors in Yirgalem General and Teaching Hospital, Southern Ethiopia: A Cross-Sectional Study

2019 ◽  
Author(s):  
Achamyelesh Tekle ◽  
Hailemichael Hagos ◽  
Kebede Tefera
Keyword(s):  
Teaching Hospital ◽  
Uterine Rupture ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Southern Ethiopia ◽  
Sectional Study ◽  
Cross Sectional ◽  
Prolonged Duration ◽  
Poor Management

Abstract Background Uterine rupture is dropped significantly in the developed world. However, it is still a major public health problem in developing countries including Ethiopia. The aim of this study was to assess management outcome of uterine rupture and its associated factors in Yirgalem General and teaching Hospital of southern Ethiopia. Methods An institution based cross-sectional study was conducted. All records of uterine rupture managed in Yirgalem general and teaching hospital between January 1, 2012, and December 30, 2017, were reviewed. Data were collected using a checklist. Descriptive statistics and logistic regression analyses were done. Results A total of 331 cases of mothers who managed for uterine rupture were included in the study. 235 (71%) of them had a poor management outcome. Wound site infection 131 (39.6%) and anemia 129 (39%) where the common post-operative complications. There were 13 (4%) maternal death and 320 (96.7%) neonatal death. Lack of antenatal care follow up (adjusted odds ratio (AOR) =2.2, 95% CI: 1.1-4.5), prolonged duration of labor more than 24hr (AOR=3.6; 95% CI: 1.7-7.4), patients presented with sepsis (AOR=2.9; 95% CI: 1.4-6.1), mothers who did not transfuse for blood during the case scenario (AOR=4; 95% CI: 2.1-7.9) and prolonged intra operative time (AOR=5.5; 95% CI: 2.8-10.8) were factors associated with poor management outcome of uterine rupture. Conclusion Poor management outcome of uterine rupture was high in the study area as compared to other studies. Lack of ANC follow up, longer duration of the surgical procedure, prolonged duration of labor, lack of blood transfusion and pre and postoperative complications are associated with poor management outcome. Therefore, proper ANC and early identification of the high-risk groups can prevent and decline the occurrence of uterine rupture and that enhance good outcome.

Prevalence of Vitamin A Deficiency And Associated Factors Among Children Aged 6-59 Months In Dera District, Northwest Ethiopia: A Cross-Sectional Study

2020 ◽  
Author(s):  
Yidrsail Hune ◽  
Hirut Asaye ◽  
Ayenew Negesse ◽  
Habtamu Temesgen ◽  
Tadesse Yirga ◽  
...  
Keyword(s):  
Vitamin A ◽  
Birth Interval ◽  
Associated Factors ◽  
Vitamin A Deficiency ◽  
Cross Sectional Study ◽  
Northwest Ethiopia ◽  
Sectional Study ◽  
Cross Sectional ◽  
Potential Health

Abstract Background: Vitamin A is a fat-soluble vitamin essential for the proper functioning of the immune system. It fondes both animal and plant sources in the form of retinol from animal sources or beta-carotene from plant source foods. Due to increased nutrient need and the severity of the potential health consequences are associated with vitamin A deficiency (VAD), preschool children and pregnant women are considered as the most at risk segments of the community. Hence, this study aimed to assess the prevalence of VAD and associated factors among children aged 6-59 months in Dera woreda, Northwest Ethiopia. Methods: Community based quantitative cross-sectional study was conducted among children aged 6-59 months in Dera woreda from December 1/2018 to January 1/2019. Multistage random sampling was used to select the required samples (267). Data were coded and entered into Epi-data version 3.1 and exported to SPSS (Statistical Package for Social Sciences) version 20 for analysis. Binary logistic regression was fitted. Both bivariable and multivariable analyses were used to identify factors associated with VAD. Those variables that were showed significant association in multivariable association at P value less than 0.05 declared as statistically significant factors of VAD among children age 6-59 months. Results: Two hundred sixty seven mother-children Pairs were included in the study making a response rate of 94.7%. The overall prevalence of Vitamin A deficiency among children age 6-59 months was 7.8% (95% CI (4.7, 11.3). Antenatal care follow up (AOR: 0.446,95 % CI (0.155, 0.980)); birth interval within 2 year (AOR: 0.392, 95 % CI (0.107, 0.839)), and age group of24-35 months (AOR; 1.206, 95 % CI (1.037, 6.129)) were significantly associated with vitamin-A deficiency. Conclusion: The overall prevalence of vitamin A deficiency in this study was found to be lower than the national and regional prevalence. According to this study, VAD is a mild public health problem. Age of children, birth interval, ANC follow up, remain the most important associated factors for vitamin A deficiency. Therefore to decrease the prevalence of VAD, ANC service should be strengthened and we should focus on older children birth interval and age- based food needs.

Prelacteal Feeding and Associated Factors Among Northwestern Ethiopian Women Having Children Less than Six Months Age: A Community Based Cross- Sectional Study

2020 ◽  
Author(s):  
Maezu G/slassie1 ◽  
Kiflay Mulugeta ◽  
Abraha Teklay Berhe
Keyword(s):  
Breast Feeding ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Prelacteal Feeding ◽  
Community Based ◽  
Cross Sectional ◽  
Timely Initiation ◽  
Factors Associated

Abstract Background: Prelacteal feeding is administration of any food or fluid other than breast milk before initiation of breast feeding. Optimal breastfeeding including discouraging prelacteal feeding could save 823,000 lives per year among children ages five years old and younger. Despite of this mothers give prelacteal feeding to their child in different part of Ethiopia; However, there is a paucity of information on prevalence of prelacteal feeding and associated factors in the study area. Thus, the current study aimed at determining of the prevalence of prelacteal feeding and associated factors among mothers of children aged less than six months in Gozamen district, East Gojjam zone, North West Ethiopia, 2019-2020Methods: A community -based cross-sectional study was conducted among 741 mothers of children aged less than six months in Gozamen district from August 2019 to Feb 2020. Stratified cluster sampling technique was used to select study participants. Data were collected by face to face interviewer-administered, pretested and semi-structured questionnaire. Descriptive analysis, bi-variable and multivariable logistic regression model were employed. Adjusted odds ratio with 95% confidence interval was used to identify factors associated with prelacteal feeding.Results: In this study the prevalence of prelacteal feeding was found to be 17.1%with 95%CI [14.3, 20]. Mothers who had no ANC follow up [AOR: 7.53, CI; 3.32, 17.05], those mothers who did not discard colostrum [AOR: 0.12, CI; 0.07, 0.12] time of breast feeding initiation [AOR: 3.53, CI; 2.05, 6.11] and mothers who had single ANC visit [AOR: 2.98, CI; 1.52, 5.85] were significant independent factors associated with prelacteal feeding.Conclusion: This study concluded that prelacteal feeding was high in the study area .Therefore, in order to tackle this problem strengthening antenatal follow up, timely initiation of breastfeeding, health education and awarenes creation of the communities are recommended interventions.

scholarly journals Sleep Quality and Associated Factors among Peoples with Epilepsy Who Have a Follow-Up at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia, 2019: An Institutional Based Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Kemeriya Adem ◽  
Tilahun Kassew ◽  
Addis Birhanu ◽  
Ayalew Abate
Keyword(s):  
Sleep Quality ◽  
Associated Factors ◽  
Addis Ababa ◽  
Cross Sectional Study ◽  
Poor Sleep ◽  
Sectional Study ◽  
Poor Sleep Quality ◽  
Cross Sectional ◽  
Specialized Hospital

Background. Sleep is an active cyclic biological phenomenon and necessary for survival. Individuals who suffer from sleep disturbance are less productive, decreased performance, and negative effects on mental health. Despite there are different studies on sleep quality in Ethiopia, no studies have been conducted on magnitude and predictors of sleep quality among people with epilepsy in the study setting. Objective. To assess sleep quality and associated factors among people with epilepsy who have a follow-up at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia, 2019. Method. An institution-based cross-sectional study was employed from May-June 2019. Systematic random sampling following face to face interview technique was employed. Epi-data version 3.1 and SPSS version 25 statistical packages were used for data entry and analysis, respectively. Frequencies, proportions, means, SDs, and cross-tabulations were used to summarize descriptive statistics of the data and tables, texts, and graphs were used for data presentation. To identify association and significant predictor with the outcome variable, binary logistic regression was fitted. The variable which has statistical significance was identified on the basis of p values ≤ 0.05 and AOR with 95% confident intervals. Results. A total of 423 participants have been enrolled to the study with a response rate of 98.1%. The prevalence of poor sleep quality among peoples live with epilepsy was found 65.4% (95% CI: 61.0, 69.9). Being female (AOR=2.94; (95% CI; 1.79, 4.85)), having stress full life events (AOR=2.38; (95% CI; 1.43, 3.97)), nonadherent to AED medication (AOR=1.86; (95% CI; 1.05, 2.78), poly-therapy treatment (AOR=2.24; (95% CI; 1.05, 2.78)), poor seizer control (AOR=2.4; (95% CI; 2.21, 12.46)), comorbid medical illness (AOR=2.6; (95% CI; 1.18, 5.61)), and anxiety (AOR=2.54; (95% CI; 1.52,4.24)) were factors significantly associated with poor sleep quality. Conclusion. This study revealed that more than half of the study participants were found to have poor sleep quality. So, considering the regular assessment of sleep quality and factors associated followed with appropriate intervention is recommended among peoples living with epilepsy.

scholarly journals Prevalence of self-reported constipation in adults from the general population

2015 ◽  
Vol 49 (3) ◽  
pp. 440-449 ◽  
Author(s):  
Fernanda Mateus Queiroz Schmidt ◽  
Vera Lúcia Conceição de Gouveia Santos ◽  
Rita de Cássia Domansky ◽  
Elaine Barros ◽  
Mariana Alves Bandeira ◽  
...  
Keyword(s):  
General Population ◽  
Associated Factors ◽  
Secondary Analysis ◽  
Bowel Function ◽  
Population Based ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Sociodemographic Data ◽  
Brazilian Version ◽  
Study Population

OBJECTIVE To estimate the prevalence of self-reported constipation and associated factors in the general population of a Brazilian city. METHOD Secondary analysis of an epidemiological study, population-based, cross-sectional study, about bowel habits of Brazilian population. A total of 2,162 individuals were interviewed using two instruments: sociodemographic data and the adapted and validated Brazilian version of the "Bowel Function in the Community" tool. RESULTS There was a prevalence of 25.2% for the self-reported constipation, 37.2% among women and 10.2% among men. Stroke and old age were associated with constipation in the three statistical models used. CONCLUSION The prevalence found showed to be similar to the findings in the literature, although some associated factors obtained here have never been investigated.

scholarly journals Incident Reporting Behaviours and Associated Factors among Nurses Working in Gondar University Comprehensive Specialized Hospital, Northwest Ethiopia

Scientifica ◽  
2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Eshetu Haileselassie Engeda
Keyword(s):  
Odds Ratio ◽  
Associated Factors ◽  
Adjusted Odds Ratio ◽  
Sampling Technique ◽  
Simple Random Sampling ◽  
Healthcare Facility ◽  
Northwest Ethiopia ◽  
Incident Reporting ◽  
Multivariate Logistic Regression Model ◽  
Cross Sectional

Background. A comprehensive and systematic approach to incident reporting would help learn from errors and adverse events within a healthcare facility.Objective. The aim of the study was to assess incident reporting behaviours and associated factors among nurses.Methods. An institution-based cross-sectional study was conducted from April 14 to 29, 2015. Simple random sampling technique was used to select the study participants. Data were coded, entered into Epi Info 7, and exported to SPSS version 20 software for analysis. A multivariate logistic regression model was fitted and adjusted odds ratio with 95% confidence interval was used to determine the strength of association.Results. The proportion of nurses who reported incidents was 25.4%. Training on incident reporting (Adjusted Odds Ratio (AOR) [95% CI] 2.96 [1.34–6.26]), reason to report (to help patient) (AOR [95% CI] 3.08 [1.70–5.59]), fear of administrative sanctions (AOR [95% CI] 0.27 [0.12–0.58]), fear of legal penalty (AOR [95% CI] 0.09 [0.03–0.21]), and fear of loss of prestige among colleagues (AOR [95% CI] 0.25 [0.12–0.53]) were significantly associated factors with the incident reporting behaviour of nurses.Conclusion and Recommendation. The proportion of nurses who reported incidents was very low. Establishing a system which promotes incident reporting is vital.

scholarly journals Prevalence of Vitamin A Deficiency And Associated Factors Among Children Aged 6-59 Months In Dera District, Northwest Ethiopia: A Cross-Sectional Study

2021 ◽  
Vol 6 (2) ◽  
Keyword(s):  
Vitamin A ◽  
Birth Interval ◽  
Associated Factors ◽  
Vitamin A Deficiency ◽  
Cross Sectional Study ◽  
Northwest Ethiopia ◽  
Sectional Study ◽  
Cross Sectional ◽  
Natal Care

Background: Vitamin A is a fat-soluble vitamin. It comes retinol from animal sources or beta-carotene from plant source. Vitamin A contains breast milk after the post-weaning period and their increased nutrient demand of children from 6-59 months, they are considered highly affected segments of the community. Hence, study assesses vitamin A deficiency and associated factors among children aged 6-59 months in Dera district, Northwest Ethiopia. Methods: Cross-sectional study design was conducted via multistage sampling techniques. Data were coded and entered into Epi-data version 3.1 and exported to Statistical Package for the Social Sciences (SPSS) version 20 for analysis. The bivariate and multiple variable logistic regression analyses were fitted. Results: Total response rate 94.7%. Prevalence of vitamin A deficiency among children age from 6-59 months was 7.8% (95% CI: 4.7, 11.3). Anti natal care (ANC) follow-up (AOR =0.446:95 % CI; 0.155, 0.980), and birth interval (AOR= 0.392: 95 % CI; 0.107, 0.839), reduces the odds of developing vitamin A deficiency; whereas age group of 36–47 months (AOR= 1.911: 95 % CI; 1.305, 11.969) increases the odds of its deficiency. Conclusion: Age of children, birth interval, ANC follow-up, Post natal care (PNC) follow-up, and place of residence were associated factors for vitamin A deficiency. Therefore more efforts should be encouraged to produce and purchase a variety of foods rich in vitamin A.

scholarly journals Predictors of Polypharmacy Among Elderly Patients in China: The Role of Decision Involvement, Depression, and Taking Chinese Medicine Behavior

2021 ◽  
Vol 12 ◽  
Author(s):  
Chaoyi Chen ◽  
Zhanchun Feng ◽  
Qian Fu ◽  
Jia Wang ◽  
Zehao Zheng ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Chinese Medicine ◽  
Chronic Diseases ◽  
Inappropriate Prescribing ◽  
Cross Sectional Study ◽  
Cluster Sampling ◽  
Prescription Data ◽  
Cross Sectional ◽  
Old Patients ◽  
Important Challenge

Introduction: The prevalence of polypharmacy is gradually increasing in geriatrics, which may contribute to adverse effects, such as potential drug–drug and drug–disease interactions. These side effects remain an important challenge in patient safety, which has a significant impact on mortality and incidence rate.Aims: Therefore, this study aims to understand the epidemiology of polypharmacy and identify factors that have an impact on the management of potentially inappropriate prescribing.Methods: This study is a cross-sectional study, analyzing the prescription data from 720 hospitalized patients aged 50+ with a random cluster sampling method. We used inverse probability treatment weighting (IPTW) method to group and match polypharmacy and non-polypharmacy patients, and logistic regression was conducted to explore the factors associated with polypharmacy.Results: The prevalence of polypharmacy accounted for 50.14% among the old patients in this study. Female patients (67.34%) have more polypharmacy than male patients, and key predictors associated with polypharmacy in the logistic regression model included the following: domicile (AOR = 0.63, 95% CI 0.42–0.95), annual income (AOR = 0.38, 95% CI 0.20–0.70), the number of chronic diseases (AOR = 3.68, 95% CI 2.69–5.06), taking Chinese medicine (AOR = 1.70, 95% CI 1.22–2.36), decision involvement (AOR = 1.49 95% CI 1.10–2.03), and depression (AOR = 1.42, 95% CI 1.03–1.96).Conclusion: Polypharmacy is common among the participants with chronic diseases in Hubei province, China. The study emphasizes that gerontology practitioners should be prudent in applying clinical guidelines to provide personalized, comprehensive assessment of decision making of prescriptions, especially in socioeconomically deprived areas.

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