The first week of October is the season to announce the winners of the Nobel Prizes of sciences such as Physics, Physiology or Medicine and Chemistry. CientMed celebrates this occasion by inviting two well known Venezuelan scientists to comment on the significance of the last two prizes, and share their corresponding deep knowledge and experience on the techniques, yes, techniques, based on the discoveries recognized this year. We are very fortunate to have among us, here in Caracas, Dr. Flor Pujol, a graduate in biology from Universidad Simón Bolívar, with an MSc and Phil. Sc., from the Venezuelan Institute of Scientific Research, IVIC. As a full Professor at IVIC, Flor is widely recognized as a leader on the molecular epidemiology and evolution of hepatitis viruses, with singular works on viruses infecting Amerindians from Venezuela. With such a background, Dr. Pujol is in a unique position to comment on the significance of the Nobel Prize of Medicine or Physiology awarded this year to, Harvey J Alter, Michael Houghton, and Charles M Rice, “For the discovery of hepatitis C virus”. On the same level of expertise but on the novel technique of CRISPR and the Nobel Prize of Chemistry this year, we also invited, Dr. José Luis Ramírez, a well known molecular biologist and a graduate from Universidad Central de Venezuela, with a Ph.D. from Johns Hopkins University, who for many years is recognized as the undisputed leader of genomic studies, on the telomeres of the parasite, Trypanosoma cruzi, the causative agent of Chagas Disease. The readers of ScienMed may remember the very first article of this journal, on August 5th, 2020, authored by Dr. Ramirez, which anticipated the Nobel Prize of Chemistry 2020, the CRISPR technologies, awarded jointly to, Emmanuelle Charpentier and Jennifer A. Doudna, “For the development of a method for genome editing”. We hope that our readers may enjoy both Commentaries by Drs. Pujol and Dr. Ramírez, respectively.