scholarly journals Simulations on the survivability of Tidal Dwarf Galaxies

2014 ◽  
Vol 10 (S309) ◽  
pp. 157-158
Author(s):  
Sylvia Ploeckinger ◽  
Simone Recchi ◽  
Gerhard Hensler ◽  
Pavel Kroupa

AbstractWe present detailed numerical simulations of the evolution of Tidal Dwarf Galaxies (TDGs) after they kinematically decouple from the rest of the tidal arm to investigate their survivability. Both the short-term (500 Myr) response of TDGs to the stellar feedback of different underlying stellar populations as well as the long-term evolution that is dominated by a time dependent tidal field is examined. All simulated TDGs survive until the end of the simulation time of up to 3 Gyr, despite their lack of a stabilising dark matter component.

2003 ◽  
Vol 95 (6) ◽  
pp. 2614-2623 ◽  
Author(s):  
A. G. Zabka ◽  
G. S. Mitchell ◽  
E. B. Olson ◽  
M. Behan

Age and the estrus cycle affect time-dependent respiratory responses to episodic hypoxia in female rats. Respiratory long-term facilitation (LTF) is enhanced in middle-aged vs. young female rats ( 72 ). We tested the hypothesis that phrenic and hypoglossal (XII) LTF are diminished in acyclic geriatric rats when fluctuating sex hormone levels no longer establish conditions that enhance LTF. Chronic intermittent hypoxia (CIH) enhances LTF ( 41 ); thus we further predicted that CIH would restore LTF in geriatric female rats. LTF was measured in young (3-4 mo) and geriatric (20-22 mo) female Sasco Sprague-Dawley rats and in a group of geriatric rats exposed to 1 wk of nocturnal CIH (11 vs. 21% O2 at 5-min intervals, 12 h/night). In anesthetized, paralyzed, vagotomized, and ventilated rats, time-dependent hypoxic phrenic and XII responses were assessed. The short-term hypoxic response was measured during the first of three 5-min episodes of isocapnic hypoxia (arterial Po2 35-45 Torr). LTF was assessed 15, 30, and 60 min postepisodic hypoxia. Phrenic and XII short-term hypoxic response was not different among groups, regardless of CIH treatment ( P > 0.05). LTF in geriatric female rats was smaller than previously reported for middle-aged rats but comparable to that in young female rats. CIH augmented phrenic and XII LTF to levels similar to those of middle-aged female rats without CIH ( P < 0.05). The magnitude of phrenic and XII LTF in all groups was inversely related to the ratio of progesterone to estradiol serum levels ( P < 0.05). Thus CIH and sex hormones influence the magnitude of LTF in geriatric female rats.


1982 ◽  
Vol 62 (2) ◽  
pp. 215-220 ◽  
Author(s):  
P. Heyma ◽  
R. G. Larkins

1. The effect of glucocorticoids on the deiodination of thyroxine (T4) to 3,5,3′-tri-iodothyronine (T3) was studied in rat renal tubules prepared by collagenase digestion. 2. In short-term (6 h) experiments, cortisol and dexamethasone inhibited the conversion of T4 into T3 at concentrations of 2 × 10-4 mol/l and 2 × 10-5 mol/l respectively. The inhibition by cortisol and dexamethasone was time dependent and was prevented by actinomycin D and progesterone, suggesting that the inhibition is mediated by an effect on nuclear transcription dependent on binding to glucocorticoid receptors. 3. In long-term (16 h) experiments, cortisol and dexamethasone inhibited T4 to T3 conversion by the tubules at concentrations of 1 × 10-12 mol/l and above. In addition, physiological concentrations of corticosterone (1 × 10-8 mol/l) were able to decrease T3 generation from T4. 4. Our data provide strong evidence that physiological concentrations of glucocorticoids are able to affect T3 production from T4 directly and suggest that they may be important regulators of T4 deiodination.


2018 ◽  
Vol 844 ◽  
pp. 766-795 ◽  
Author(s):  
Sergei Y. Annenkov ◽  
Victor I. Shrira

Kinetic equations are widely used in many branches of science to describe the evolution of random wave spectra. To examine the validity of these equations, we study numerically the long-term evolution of water wave spectra without wind input using three different models. The first model is the classical kinetic (Hasselmann) equation (KE). The second model is the generalised kinetic equation (gKE), derived employing the same statistical closure as the KE but without the assumption of quasistationarity. The third model, which we refer to as the DNS-ZE, is a direct numerical simulation algorithm based on the Zakharov integrodifferential equation, which plays the role of the primitive equation for a weakly nonlinear wave field. It does not employ any statistical assumptions. We perform a comparison of the spectral evolution of the same initial distributions without forcing, with/without a statistical closure and with/without the quasistationarity assumption. For the initial conditions, we choose two narrow-banded spectra with the same frequency distribution and different degrees of directionality. The short-term evolution ($O(10^{2})$ wave periods) of both spectra has been previously thoroughly studied experimentally and numerically using a variety of approaches. Our DNS-ZE results are validated both with existing short-term DNS by other methods and with available laboratory observations of higher-order moment (kurtosis) evolution. All three models demonstrate very close evolution of integral characteristics of the spectra, approaching with time the theoretical asymptotes of the self-similar stage of evolution. Both kinetic equations give almost identical spectral evolution, unless the spectrum is initially too narrow in angle. However, there are major differences between the DNS-ZE and gKE/KE predictions. First, the rate of angular broadening of initially narrow angular distributions is much larger for the gKE and KE than for the DNS-ZE, although the angular width does appear to tend to the same universal value at large times. Second, the shapes of the frequency spectra differ substantially (even when the nonlinearity is decreased), the DNS-ZE spectra being wider than the KE/gKE ones and having much lower spectral peaks. Third, the maximal rates of change of the spectra obtained with the DNS-ZE scale as the fourth power of nonlinearity, which corresponds to the dynamical time scale of evolution, rather than the sixth power of nonlinearity typical of the kinetic time scale exhibited by the KE. The gKE predictions fall in between. While the long-term DNS show excellent agreement with the KE predictions for integral characteristics of evolving wave spectra, the striking systematic discrepancies for a number of specific spectral characteristics call for revision of the fundamentals of the wave kinetic description.


2013 ◽  
Vol 10 (82) ◽  
pp. 20130026 ◽  
Author(s):  
Michael E. Palmer ◽  
Arnav Moudgil ◽  
Marcus W. Feldman

It has long been debated whether natural selection acts primarily upon individual organisms, or whether it also commonly acts upon higher-level entities such as lineages. Two arguments against the effectiveness of long-term selection on lineages have been (i) that long-term evolutionary outcomes will not be sufficiently predictable to support a meaningful long-term fitness and (ii) that short-term selection on organisms will almost always overpower long-term selection. Here, we use a computational model of protein folding and binding called ‘lattice proteins’. We quantify the long-term evolutionary success of lineages with two metrics called the k -fitness and k -survivability. We show that long-term outcomes are surprisingly predictable in this model: only a small fraction of the possible outcomes are ever realized in multiple replicates. Furthermore, the long-term fitness of a lineage depends only partly on its short-term fitness; other factors are also important, including the ‘evolvability’ of a lineage—its capacity to produce adaptive variation. In a system with a distinct short-term and long-term fitness, evolution need not be ‘short-sighted’: lineages may be selected for their long-term properties, sometimes in opposition to short-term selection. Similar evolutionary basins of attraction have been observed in vivo , suggesting that natural biological lineages will also have a predictive long-term fitness.


2006 ◽  
Vol 2 (S237) ◽  
pp. 323-330 ◽  
Author(s):  
Pierre-Alain Duc ◽  
Frédéric Bournaud ◽  
Médéric Boquien

AbstractStar formation may take place in a variety of locations in interacting systems: in the dense core of mergers, in the shock regions at the interface of the colliding galaxies and even within the tidal debris expelled into the intergalactic medium. Along tidal tails, objects may be formed with masses ranging from those of super-star clusters to dwarf galaxies: the so-called Tidal Dwarf Galaxies (TDGs). Based on a set of multi-wavelength observations and extensive numerical simulations, we show how TDGs may simultaneously be used as laboratories to study the process of star-formation (SFE, IMF) in a specific environment and as probes of various cosmological properties, such as the distribution of dark matter and satellites around galaxies.


2020 ◽  
Author(s):  
Lizz Ultee ◽  
Bryan Riel ◽  
Brent Minchew

&lt;p&gt;The rate of ice flux from the Greenland Ice Sheet to the ocean depends on the ice flow velocity through outlet glaciers. Ice flow velocity, in turn, evolves in response to multiple geographic and environmental forcings at different timescales. For example, velocity may vary daily in response to ocean tides, seasonally in response to surface air temperature, and multi-annually in response to long-term trends in climate. The satellite observations processed as part of the NASA MEaSUREs Greenland Ice Sheet Velocity Map allow us to analyse variations in ice surface velocity at multiple timescales. Here, we decompose short-term and long-term signals in time-dependent velocity fields for Greenland outlet glaciers based on the methods of Riel et al. (2018). Patterns found in short-term signals can constrain basal sliding relations and ice rheology, while the longer-term signals hint at decadal in/stability of outlet glaciers. We present example velocity time series for outlets including Sermeq Kujalleq (Jakobshavn Isbrae) and Helheim Glacier, and we highlight features indicative of dynamic drawdown or advective restabilization. Finally, we comment on the capabilities of a time series analysis software under development for glaciological applications.&lt;/p&gt;


2008 ◽  
Vol 4 (S255) ◽  
pp. 246-253
Author(s):  
Frédéric Galliano

AbstractThis paper presents the results of a study aimed at understanding the evolution of the dust properties, as a function of both the environmental conditions and the metal enrichment of the system. I first review the peculiar dust properties of dwarf galaxies, and discuss attempts to understand their origin. Then, I discuss the evolution of the PAH and dust abundances, constrained by the UV-to-radio SED of nearby galaxies, comparing the properties of low-metallicity environments and more evolved systems. I discuss the long term evolution of dust in galaxies, comparing the grain production by various stellar progenitors to their destruction by SN blast waves and in H ii regions. Finally, I will show how these models explain the paucity of PAHs in low-metallicity environments.


2018 ◽  
Vol 56 (4) ◽  
pp. 669-680 ◽  
Author(s):  
Seline Zurfluh ◽  
Manuela Nickler ◽  
Manuel Ottiger ◽  
Christian Steuer ◽  
Alexander Kutz ◽  
...  

Abstract Background: The release of hormones from the adrenal gland is vital in acute and chronic illnesses such as chronic obstructive pulmonary disease (COPD) involving recurrent exacerbations. Using a metabolomic approach, we aim to investigate associations of different adrenal hormone metabolites with short- and long-term mortality in COPD patients. Methods: We prospectively followed 172 COPD patients (median age 75 years, 62% male) from a previous Swiss multicenter trial. At baseline, we measured levels of a comprehensive spectrum of adrenal hormone metabolites, including glucocorticoid, mineralocorticoid and androgen hormones by liquid chromatography coupled with tandem mass spectrometry (MS). We calculated Cox regression models adjusted for gender, age, comorbidities and previous corticosteroid therapy. Results: Mortality was 6.4% after 30 days and increased to 61.6% after 6 years. Higher initial androgen hormones predicted lower long-term mortality with significant results for dehydroepiandrosterone (DHEA) [adjusted hazard ratio (HR), 0.82; 95% confidence interval (CI), 0.70–0.98; p=0.026] and dehydroepiandrosterone sulfate (DHEA-S) (adjusted HR, 0.68; 95% CI, 0.50–0.91; p=0.009). An activation of stress hormones (particularly cortisol and cortisone) showed a time-dependent effect with higher levels pointing towards higher mortality at short term, but lower mortality at long term. Activation of the mineralocorticoid axis tended to be associated with increased short-term mortality (adjusted HR of aldosterone, 2.76; 95% CI, 0.79–9.65; p=0.111). Conclusions: Independent of age, gender, corticosteroid exposure and exacerbation type, adrenal hormones are associated with mortality at short and long term in patients with COPD exacerbation with different time-dependent effects of glucocorticoids, androgens and mineralocorticoids. A better physiopathological understanding of the causality of these effects may have therapeutic implications.


2017 ◽  
Vol 50 (3) ◽  
pp. 1309
Author(s):  
R. Console

This presentation outlines methodological aspects of earthquake forecasting. The recurring debates concerning predictability of earthquakes clearly show how this problem is centred on the difficulty of systematically testing the numerous methodologies that in the years have been proposed and sustained by the supporters of prediction. This difficulty starts, sometimes, from the lack of a quantitative and rigorous definition of the concerned precursor, and other times from the lack of continuous observations, upon which statistical analyses could be based. After an introduction concerning the definition of earthquake precursors, the way how to validate forecast hypotheses and the cost associated to their operational application, I give two examples of time-dependent hazard models, for long-term and short-term earthquake forecasts respectively. Considering the long-term forecast modelling, the effect of stress change due to previous historical earthquakes on the probability of occurrence of future earthquakes on neighbouring faults is taken into account. Following a standard methodology developed a couple of decades ago, the probability of occurrence in the next 50 years for a characteristic earthquake on known seismogenic structures can be estimated by a time-dependent renewal model. Then, a physical model for the Coulomb stress change caused by previous earthquakes on these structures is applied. The influence of this stress change on the occurrence rate of characteristic earthquakes is computed taking into account the permanent perturbation (clock advance). The method so developed is applied to the computation of earthquake hazard of the main seismogenic structures recognized in the Southern Apennines region, for which both historical and paleoseismological data are available. A popular short-term time dependent hazard forecast model is the epidemic model. In this model earthquakes are regarded as the realization of a stochastic point process, and their magnitude distribution is described by the Gutenberg-Richter law with a constant b-value. The occurrence rate density is computed by the sum of two terms, one representing the independent, or spontaneous activity, and the other representing the activity induced by previous earthquakes. While the first term depends only on space, the second one is factored into three terms that respectively include the magnitude, time and location of the past earthquakes. An example of application of the epidemic model to the 2009 L’Aquila seismic series is shown.


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