Effect of level of fish oil in the diet on flow of fatty acids to the small intestine in steers

2007 ◽  
Vol 2007 ◽  
pp. 151-151 ◽  
Author(s):  
E. J. Kim ◽  
J. D. Wood ◽  
I. Richardson ◽  
S. A. Huws ◽  
N. D. Scollan
Keyword(s):  
Fatty Acids ◽  
Small Intestine ◽  
Fatty Acid ◽  
Linoleic Acid ◽  
Beef Cattle ◽  
Fish Oil ◽  
Fatty Acid Metabolism ◽  
Acid Metabolism ◽  
Vaccenic Acid ◽  
Long Chain

Previous studies have shown that including fish oil (FO) in the diet of beef cattle resulted in increased long chain C20n-3 PUFA (C20:5n-3 and C22:6n-3) in muscle resulting in a lower n-6:n-3 ratio (Scollan et al., 2005). Fish oil is considered to be a good inhibitor of biohydrogenation in the rumen, resulting in increased production of C18:1 trans-11 (Vaccenic acid), the precursor for conjugated linoleic acid (CLA cis-9, trans-11) in muscle. This study investigated the effects of incremental levels of FO in the diet on fatty acid metabolism in the rumen.

scholarly journals Role of Serum Fatty Acids in Children with Henoch-Schönlein purpura by GC-MS analysis

2020 ◽  
Author(s):  
Min Wen ◽  
shipin feng ◽  
xiqiang dang ◽  
xuewei ding ◽  
zhiquan xu ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Fatty Acid Metabolism ◽  
Renal Damage ◽  
Acid Metabolism ◽  
Henoch Schonlein Purpura ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura ◽  
Long Chain ◽  
Serum Fatty Acids

Abstract BACKGROUND: The objectives of this work were to discover the changes of serum Medium- and Long-Chain fatty acids levels and its possible relationship with Henoch-Schönlein Purpura (HSP), also referred to as Immunoglobulin A vasculitis in children. METHODS: A total of 58 children with HSP and 28 healthy children were recruited for this study. Serum fatty acids were analyzed by gas chromatography with mass spectrometry (GC-MS). RESULTS: 31 species of Fatty acids were discovered to have a significant difference between HSP group and healthy control group (CON group). The contents of all detected 37 fatty acids in the HSP group were higher than the healthy group. Parts of fatty acids were found in our study having significant change according to the treatment. Palmitate (C16:0) and 18 carbon atoms (C18) of fatty acids were abundant in all three groups of HSP. Elaidate (C18:1T), cis-11,14,17-Eicosatrienoic acid ester (C20:1) and cis-15-tetracosenoate (C24:1) were found to have a correlation on renal damage of HSP. CONCLUSION: Our study provides clinical evidence to support that fatty acid metabolism is associated with HSP by GC-MS method. Glucocorticoid therapy has a certain relationship with fatty acid metabolism during HSP treatment. Meanwhile, long-chain MUFAs may have an impact on renal damage of HSP. In addition, we speculate that a low BMI may be a kind of manifestation of abnormal fatty acid metabolism in HSP. All in all, further study is needed to explore the specific mechanism of fatty acids and HSP.

The effects of fish oil supplementation on rumen metabolism and the biohydrogenation of unsaturated fatty acids in beef steers given diets containing sunflower oil

2005 ◽  
Vol 80 (3) ◽  
pp. 361-367 ◽  
Author(s):  
M. R. F. Lee ◽  
J. K. S. Tweed ◽  
A. P. Moloney ◽  
N. D. Scollan
Keyword(s):  
Fatty Acid ◽  
Linoleic Acid ◽  
Stearic Acid ◽  
Fish Oil ◽  
Sunflower Oil ◽  
Vaccenic Acid ◽  
Ruminal Ph ◽  
Chain Pufa ◽  
N Concentration ◽  
Long Chain

AbstractDuodenally and ruminally fistulated steers were offered grass silage and one of three concentrates at a ratio of 60: 40 (forage: concentrate on a dry-matter basis) : F0, F1 or F4 at 14 g/kg live weight. The concentrates were designed to be iso-lipid and to provide the same amount of sunflower oil but increasing amounts of fish oil : 0, 1 and 4 g per 100 g, respectively. Ruminal characteristics were measured along with fatty acid intakes and duodenal flows to determine the effect of fish oil on : ruminal pH, ammonia-N concentration, volatile fatty acid (VFA) concentration and polyunsaturated fatty acid (PUFA) metabolism. Fish oil had no significant effect on ruminal pH, ammonia-N concentration or the molar proportions of the major VFA, although total VFA concentration was significantly reduced at the highest level of fish oil inclusion. Fish oil significantly increased the flow of long chain PUFA, total conjugated linoleic acid and vaccenic acid to the duodenum and decreased the flow of stearic acid. Biohydrogenation, as determined by the net loss of fatty acid between the mouth and duodenum, of oleic and linolenic acid was not affected by fish oil inclusion and averaged 0·64 and 0·92, respectively. There was a small increase in the biohydrogenation of linoleic acid with increasing fish oil from 0·89 to 0·92 (P< 0·01) on F0 and F4, respectively. Biohydrogenation of the long chain PUFA C20 : 5(n-3) and C22 : 6(n-3) increased from 0·49 and 0·74 to 0·79 and 0·86 (P< 0·01), respectively when fish oil in the concentrate increased from 1 to 4 g per 100 g. The net effect of fish oil on lipid metabolism appears to inhibit the transition of vaccenic acid to stearic acid in the rumen resulting in a build up of this intermediate in the biohydrogenation pathway of C18 PUFA.

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