scholarly journals Mobility-Resolved Ion Selection in Uniform Drift Field Ion Mobility Spectrometry/Mass Spectrometry: Dynamic Switching in Structures for Lossless Ion Manipulations

2014 ◽  
Vol 86 (19) ◽  
pp. 9632-9637 ◽  
Author(s):  
Ian K. Webb ◽  
Sandilya V. B. Garimella ◽  
Aleksey V. Tolmachev ◽  
Tsung-Chi Chen ◽  
Xinyu Zhang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Dynamic Switching ◽  
Drift Field ◽  
Uniform Drift

scholarly journals Use of Cyclic Ion Mobility Spectrometry (cIM)-Mass Spectrometry to Study the Intramolecular Transacylation of Diclofenac Acyl Glucuronide

2021 ◽  
Author(s):  
David Higton ◽  
Martin E. Palmer ◽  
Johannes P. C. Vissers ◽  
Lauren G. Mullin ◽  
Robert S. Plumb ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Acyl Glucuronide

scholarly journals Ion Mobility–Mass Spectrometry for Bioanalysis

Separations ◽  
2021 ◽  
Vol 8 (3) ◽  
pp. 33
Author(s):  
Xavier Garcia ◽  
Maria del Mar Sabaté ◽  
Jorge Aubets ◽  
Josep Maria Jansat ◽  
Sonia Sentellas
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Biological Samples ◽  
Ion Mobility Mass Spectrometry ◽  
Exogenous Compounds ◽  
Analytical Separation

This paper aims to cover the main strategies based on ion mobility spectrometry (IMS) for the analysis of biological samples. The determination of endogenous and exogenous compounds in such samples is important for the understanding of the health status of individuals. For this reason, the development of new approaches that can be complementary to the ones already established (mainly based on liquid chromatography coupled to mass spectrometry) is welcomed. In this regard, ion mobility spectrometry has appeared in the analytical scenario as a powerful technique for the separation and characterization of compounds based on their mobility. IMS has been used in several areas taking advantage of its orthogonality with other analytical separation techniques, such as liquid chromatography, gas chromatography, capillary electrophoresis, or supercritical fluid chromatography. Bioanalysis is not one of the areas where IMS has been more extensively applied. However, over the last years, the interest in using this approach for the analysis of biological samples has clearly increased. This paper introduces the reader to the principles controlling the separation in IMS and reviews recent applications using this technique in the field of bioanalysis.

Compensation voltage shifting in high-field asymmetric waveform ion mobility spectrometry-mass spectrometry

2006 ◽  
Vol 20 (22) ◽  
pp. 3319-3329 ◽  
Author(s):  
Beata M. Kolakowski ◽  
Margaret A. McCooeye ◽  
Zoltan Mester
Keyword(s):  
Mass Spectrometry ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
High Field ◽  
Compensation Voltage ◽  
Asymmetric Waveform

scholarly journals Rapid determination of N-methylpyrrolidine in cefepime by combining direct infusion electrospray ionisation-time-of-flight mass spectrometry with field asymmetric waveform ion mobility spectrometry

2015 ◽  
Vol 7 (1) ◽  
pp. 34-39 ◽  
Author(s):  
Robert W. Smith ◽  
Lisa B. Cox ◽  
Aswandi Yudin ◽  
James C. Reynolds ◽  
Mark Powell ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Rapid Determination ◽  
Time Of Flight ◽  
Asymmetric Waveform ◽  
Direct Infusion ◽  
Electrospray Ionisation ◽  
Flight Mass Spectrometry

FAIMS separation prior to mass spectrometry enables selective transmission of NMP in cefepime without interference from NMP formed by in-source CID.

Calculation of ion mobilities from electrospray ionization high-field asymmetric waveform ion mobility spectrometry mass spectrometry

2001 ◽  
Vol 114 (23) ◽  
pp. 10270-10277 ◽  
Author(s):  
Roger Guevremont ◽  
David A. Barnett ◽  
Randy W. Purves ◽  
Larry A. Viehland
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Ionization ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
High Field ◽  
Asymmetric Waveform
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